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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Mybl2
Z-value: 0.50
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Transcription factors associated with Mybl2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mybl2 | rn6_v1_chr3_+_159421671_159421671 | 0.24 | 7.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_88964525 Show fit | 0.35 |
ENSRNOT00000068236
|
dynein assembly factor with WD repeats 1 |
|
| chr13_+_83681322 Show fit | 0.23 |
ENSRNOT00000004206
|
mitochondrial pyruvate carrier 2 |
|
| chr2_+_58724855 Show fit | 0.22 |
ENSRNOT00000089609
|
calcyphosine-like |
|
| chr8_+_52829085 Show fit | 0.22 |
ENSRNOT00000007754
|
similar to hypothetical protein FLJ20010 |
|
| chr1_-_166943592 Show fit | 0.21 |
ENSRNOT00000026962
|
folate receptor 1 |
|
| chr10_+_14828597 Show fit | 0.17 |
ENSRNOT00000025434
|
tektin 4 |
|
| chr10_-_56531483 Show fit | 0.15 |
ENSRNOT00000022343
|
eukaryotic translation initiation factor 5A |
|
| chr2_+_197682000 Show fit | 0.15 |
ENSRNOT00000066821
|
HORMA domain containing 1 |
|
| chr2_+_127538659 Show fit | 0.15 |
ENSRNOT00000093483
ENSRNOT00000058476 |
solute carrier family 25 member 31 |
|
| chr9_-_30251388 Show fit | 0.15 |
ENSRNOT00000035033
|
succinate dehydrogenase complex assembly factor 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Mybl2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0045144 | meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) |
| 0.1 | 0.2 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 0.2 | GO:0060974 | cell migration involved in heart formation(GO:0060974) |
| 0.0 | 0.2 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.0 | 0.2 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.0 | 0.2 | GO:0045901 | regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901) |
| 0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.1 | GO:0061740 | protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) |
| 0.0 | 0.1 | GO:0046066 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066) |
| 0.0 | 0.1 | GO:0061741 | vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.1 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
| 0.0 | 0.1 | GO:1990826 | nucleoplasmic periphery of the nuclear pore complex(GO:1990826) |
| 0.0 | 0.1 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.1 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) lysosomal matrix(GO:1990836) |
| 0.0 | 0.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.0 | 0.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.0 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.1 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.0 | 0.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.0 | 0.1 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.0 | 0.1 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.0 | 0.1 | GO:0032551 | UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 0.1 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |