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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Mybl1
Z-value: 0.99
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Transcription factors associated with Mybl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mybl1 | rn6_v1_chr5_+_9279970_9279970 | 0.20 | 7.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_15540177 Show fit | 0.47 |
ENSRNOT00000022113
|
transthyretin |
|
| chrM_+_9870 Show fit | 0.39 |
ENSRNOT00000044582
|
mitochondrially encoded NADH 4L dehydrogenase |
|
| chr5_+_6373583 Show fit | 0.37 |
ENSRNOT00000084749
|
|
|
| chr20_-_3793985 Show fit | 0.37 |
ENSRNOT00000049540
ENSRNOT00000086293 |
RT1 class I, locus CE16 |
|
| chr8_-_55696601 Show fit | 0.31 |
ENSRNOT00000016127
|
RGD1562914 |
|
| chr1_+_213583606 Show fit | 0.30 |
ENSRNOT00000088899
|
|
|
| chr2_+_118547190 Show fit | 0.29 |
ENSRNOT00000083676
ENSRNOT00000090301 ENSRNOT00000013410 |
potassium calcium-activated channel subfamily M regulatory beta subunit 2 |
|
| chr9_-_9143189 Show fit | 0.27 |
ENSRNOT00000089904
|
similar to RIKEN cDNA 1700001E04 |
|
| chr6_-_114488880 Show fit | 0.25 |
ENSRNOT00000087560
|
|
|
| chr8_-_96547568 Show fit | 0.25 |
ENSRNOT00000078343
|
similar to RIKEN cDNA 4930579C12 gene |
Network of associatons between targets according to the STRING database.
First level regulatory network of Mybl1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 0.3 | GO:0006431 | methionyl-tRNA aminoacylation(GO:0006431) |
| 0.0 | 0.3 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.3 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.1 | 0.2 | GO:0061091 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 0.2 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.1 | 0.2 | GO:1904612 | glucuronoside metabolic process(GO:0019389) response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) |
| 0.1 | 0.2 | GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.1 | GO:1903767 | sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768) |
| 0.0 | 0.1 | GO:0045025 | mitochondrial degradosome(GO:0045025) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.4 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.3 | GO:0004825 | methionine-tRNA ligase activity(GO:0004825) |
| 0.1 | 0.3 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.0 | 0.3 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.1 | 0.2 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
| 0.1 | 0.2 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.2 | GO:0036137 | kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) |
| 0.0 | 0.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.1 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.4 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.3 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.2 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.2 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |