ISMARA results: Msx3

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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Msx3

Z-value: 0.42

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Transcription factors associated with Msx3

Gene Symbol	Gene ID	Gene Info
Msx3 NCBI RGD Ensembl	ENSRNOG00000046776	msh homeobox 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Msx3	rn6_v1_chr1_-_212517151_212517151	0.13	8.3e-01	Click!

Activity profile of Msx3 motif

Sorted Z-values of Msx3 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chrM_+_9870 Show fit	0.13	ENSRNOT00000044582	Mt-nd4l NCBI RGD Ensembl Show fit	mitochondrially encoded NADH 4L dehydrogenase
chr3_-_90751055 Show fit	0.12	ENSRNOT00000040741	LOC499843 NCBI RGD Ensembl Show fit	LRRGT00091
chr4_+_147832136 Show fit	0.12	ENSRNOT00000064603	Rho NCBI RGD Ensembl Show fit	rhodopsin
chr5_+_6373583 Show fit	0.12	ENSRNOT00000084749	AABR07046778.1 NCBI RGD Ensembl Show fit
chr6_-_76552559 Show fit	0.12	ENSRNOT00000065230	Ralgapa1 NCBI RGD Ensembl Show fit	Ral GTPase activating protein catalytic alpha subunit 1
chr9_+_73378057 Show fit	0.11	ENSRNOT00000043627 ENSRNOT00000045766 ENSRNOT00000092445 ENSRNOT00000037974	Map2 NCBI RGD Ensembl Show fit	microtubule-associated protein 2
chr2_-_219262901 Show fit	0.11	ENSRNOT00000037068	Gpr88 NCBI RGD Ensembl Show fit	G-protein coupled receptor 88
chr3_-_165700489 Show fit	0.10	ENSRNOT00000017008	Zfp93 NCBI RGD Ensembl Show fit	zinc finger protein 93
chr13_+_96303703 Show fit	0.09	ENSRNOT00000084718 ENSRNOT00000029723	Efcab2 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 2
chr15_-_55209342 Show fit	0.08	ENSRNOT00000021752	Rb1 NCBI RGD Ensembl Show fit	RB transcriptional corepressor 1

Showing 1 to 10 of 68 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.1	GO:1903944	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	GO:0061743	motor learning(GO:0061743)
0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.0	GO:0051684	maintenance of Golgi location(GO:0051684)

Showing 1 to 6 of 6 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.1	GO:0009378	four-way junction helicase activity(GO:0009378)

Showing 1 to 4 of 4 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins

Showing 1 to 1 of 1 entries

Results for Msx3

Z-value: 0.42

Motif logo

Transcription factors associated with Msx3

Activity-expression correlation:

Activity profile of Msx3 motif

Sorted Z-values of Msx3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: