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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Msx2_Hoxd4

Z-value: 0.27

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Transcription factors associated with Msx2_Hoxd4

Gene Symbol Gene ID Gene Info
ENSRNOG00000018355 msh homeobox 2
ENSRNOG00000001578 homeo box D4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Msx2rn6_v1_chr17_+_11683862_11683862-0.414.9e-01Click!

Activity profile of Msx2_Hoxd4 motif

Sorted Z-values of Msx2_Hoxd4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_86671515 0.07 ENSRNOT00000082869

chr2_+_72006099 0.06 ENSRNOT00000034044
cadherin 12
chr6_-_76552559 0.06 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr9_-_30844199 0.06 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr2_-_31753528 0.05 ENSRNOT00000075057
phosphoinositide-3-kinase regulatory subunit 1
chr20_+_25990656 0.05 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr19_+_25043680 0.05 ENSRNOT00000043971
adhesion G protein-coupled receptor L1
chr5_-_168734296 0.05 ENSRNOT00000066120
calmodulin binding transcription activator 1
chrX_+_908044 0.04 ENSRNOT00000072087
zinc finger protein 300
chr15_+_56666012 0.04 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr1_-_166912524 0.04 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr13_-_76049363 0.04 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr6_+_64789940 0.03 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr6_+_27887797 0.03 ENSRNOT00000015827
additional sex combs like 2, transcriptional regulator
chr14_+_38192870 0.03 ENSRNOT00000077080
nuclear transcription factor, X-box binding-like 1
chr9_+_52687868 0.03 ENSRNOT00000083864
WD repeat domain 75
chr19_-_22194740 0.03 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr1_+_47032113 0.03 ENSRNOT00000024412
tubby like protein 4
chr11_-_29710849 0.03 ENSRNOT00000029345
keratin associated protein 11-1
chr3_-_25212049 0.03 ENSRNOT00000040023
LDL receptor related protein 1B
chr2_-_35104963 0.03 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr18_-_1828606 0.03 ENSRNOT00000033312
establishment of sister chromatid cohesion N-acetyltransferase 1
chr2_+_127489771 0.03 ENSRNOT00000093581
inturned planar cell polarity protein
chr9_-_63641400 0.03 ENSRNOT00000087684
SATB homeobox 2
chr15_-_71779033 0.03 ENSRNOT00000017765
protocadherin 20
chrX_+_84064427 0.03 ENSRNOT00000046364
zinc finger protein 711
chr3_-_90751055 0.02 ENSRNOT00000040741
LRRGT00091
chr2_-_33025271 0.02 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr13_+_46169963 0.02 ENSRNOT00000005212
thrombospondin type 1 domain containing 7B
chr11_-_90406797 0.02 ENSRNOT00000073049
snail family transcriptional repressor 2
chr13_+_90533365 0.02 ENSRNOT00000082469
DDB1 and CUL4 associated factor 8
chr8_+_70317586 0.02 ENSRNOT00000016260
DENN domain containing 4A
chr7_+_122818975 0.02 ENSRNOT00000000206
E1A binding protein p300
chr12_-_35979193 0.02 ENSRNOT00000071104
transmembrane protein 132B
chr2_-_30634243 0.02 ENSRNOT00000077537
MARVEL domain containing 2
chr5_+_104698040 0.02 ENSRNOT00000009127
ADAMTS-like 1
chr20_+_27975549 0.02 ENSRNOT00000092075
LIM zinc finger domain containing 1
chr14_+_48768537 0.02 ENSRNOT00000082599
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_42304534 0.02 ENSRNOT00000085097
KIT ligand
chr2_+_196013799 0.02 ENSRNOT00000084023
pogo transposable element with ZNF domain
chr5_-_154363329 0.02 ENSRNOT00000064596
elongin A
chr16_-_54137660 0.02 ENSRNOT00000085435
pericentriolar material 1
chr19_+_32308236 0.02 ENSRNOT00000015508
methylmalonic aciduria (cobalamin deficiency) cblA type
chr2_-_196377883 0.02 ENSRNOT00000028661
GA binding protein transcription factor, beta subunit 2
chr19_+_43163129 0.01 ENSRNOT00000073721
C-type lectin domain family 18, member A
chr8_-_96266342 0.01 ENSRNOT00000078891
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_94834908 0.01 ENSRNOT00000006284
trans-L-3-hydroxyproline dehydratase
chr6_+_69971227 0.01 ENSRNOT00000075349
forkhead box G1
chr10_-_90940118 0.01 ENSRNOT00000093143
elongation factor Tu GTP binding domain containing 2
chr11_-_782954 0.01 ENSRNOT00000040065
Eph receptor A3
chr3_-_52447622 0.01 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr5_-_48436531 0.01 ENSRNOT00000060914
peptidase M20 domain containing 2
chr17_-_53713408 0.01 ENSRNOT00000022445
AT-rich interactive domain-containing protein 4B-like
chrX_-_106607352 0.01 ENSRNOT00000082858

chrM_+_8599 0.01 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr14_-_45859908 0.01 ENSRNOT00000086994
phosphoglucomutase 2
chr2_-_181531978 0.01 ENSRNOT00000072029
neuropeptide Y receptor Y2
chr4_-_129619142 0.01 ENSRNOT00000047453
leiomodin 3
chr11_+_61605937 0.01 ENSRNOT00000093455
ENSRNOT00000093242
GRAM domain containing 1C
chr2_+_165805144 0.01 ENSRNOT00000073716
RAB interacting factor
chr2_-_210766501 0.01 ENSRNOT00000025800
glutathione S-transferase mu 3
chr20_+_9948908 0.01 ENSRNOT00000001541
ubiquitin associated and SH3 domain containing, A
chr2_-_219262901 0.00 ENSRNOT00000037068
G-protein coupled receptor 88
chr10_-_87521514 0.00 ENSRNOT00000084668
ENSRNOT00000071705
keratin associated protein 2-4-like
chr5_-_12172009 0.00 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr16_+_50049828 0.00 ENSRNOT00000034448
family with sequence similarity 149, member A
chr2_+_54466280 0.00 ENSRNOT00000033112
complement C6
chrM_+_7006 0.00 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr10_+_65733991 0.00 ENSRNOT00000013698
solute carrier family 46 member 1
chrM_+_7919 0.00 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr1_+_22364551 0.00 ENSRNOT00000043157
trace amine-associated receptor 8a
chr16_+_61926586 0.00 ENSRNOT00000058884

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx2_Hoxd4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)