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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Meox2
Z-value: 0.59
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Transcription factors associated with Meox2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Meox2 | rn6_v1_chr6_+_56625650_56625650 | 0.66 | 2.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrM_+_9870 Show fit | 0.51 |
ENSRNOT00000044582
|
mitochondrially encoded NADH 4L dehydrogenase |
|
| chr5_+_6373583 Show fit | 0.40 |
ENSRNOT00000084749
|
|
|
| chrM_+_9451 Show fit | 0.25 |
ENSRNOT00000041241
|
mitochondrially encoded NADH dehydrogenase 3 |
|
| chrM_+_11736 Show fit | 0.20 |
ENSRNOT00000048767
|
mitochondrially encoded NADH dehydrogenase 5 |
|
| chr10_+_31647898 Show fit | 0.19 |
ENSRNOT00000066536
|
similar to kidney injury molecule 1 |
|
| chrM_+_10160 Show fit | 0.18 |
ENSRNOT00000042928
|
mitochondrially encoded NADH dehydrogenase 4 |
|
| chr1_+_228684136 Show fit | 0.17 |
ENSRNOT00000028608
|
olfactory receptor 337 |
|
| chr1_-_225631468 Show fit | 0.16 |
ENSRNOT00000072579
|
|
|
| chr16_+_74810938 Show fit | 0.16 |
ENSRNOT00000058091
|
NIMA-related kinase 5 |
|
| chr18_+_62852303 Show fit | 0.15 |
ENSRNOT00000087673
|
G protein subunit alpha L |
Network of associatons between targets according to the STRING database.
First level regulatory network of Meox2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 0.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.3 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.0 | 0.1 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.0 | 0.1 | GO:0018283 | metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) |
| 0.0 | 0.1 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.0 | 0.1 | GO:0002838 | negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 0.0 | 0.1 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.0 | 0.1 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 0.1 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.0 | 0.0 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.3 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.2 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 0.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.0 | 0.1 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.0 | 0.1 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 0.0 | 0.1 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.0 | 0.1 | GO:0001642 | group III metabotropic glutamate receptor activity(GO:0001642) |
| 0.0 | 0.1 | GO:0071886 | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886) |
| 0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |