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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Meox1
Z-value: 0.50
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Transcription factors associated with Meox1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Meox1 | rn6_v1_chr10_-_89816491_89816491 | 0.42 | 4.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_123106694 Show fit | 0.71 |
ENSRNOT00000028829
|
oxytocin/neurophysin 1 prepropeptide |
|
| chr5_+_50381244 Show fit | 0.48 |
ENSRNOT00000012385
|
glycoprotein hormones, alpha polypeptide |
|
| chr1_+_87224677 Show fit | 0.32 |
ENSRNOT00000028070
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A |
|
| chr1_+_80279706 Show fit | 0.16 |
ENSRNOT00000047105
|
protein phosphatase 1, regulatory subunit 13 like |
|
| chr7_-_143353925 Show fit | 0.16 |
ENSRNOT00000068533
|
keratin 71 |
|
| chr2_-_25235275 Show fit | 0.14 |
ENSRNOT00000061580
|
F2R like trypsin receptor 1 |
|
| chr6_+_34155017 Show fit | 0.14 |
ENSRNOT00000073663
|
tetratricopeptide repeat domain 32 |
|
| chr18_-_24735349 Show fit | 0.13 |
ENSRNOT00000036537
|
G protein-coupled receptor 17 |
|
| chr6_-_123577695 Show fit | 0.12 |
ENSRNOT00000006604
|
forkhead box N3 |
|
| chr20_+_40769586 Show fit | 0.12 |
ENSRNOT00000001079
|
fatty acid binding protein 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Meox1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.7 | GO:0043134 | hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) |
| 0.0 | 0.5 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.0 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568) |
| 0.0 | 0.1 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 0.0 | 0.1 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.0 | 0.1 | GO:0045575 | basophil activation(GO:0045575) |
| 0.0 | 0.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.0 | 0.1 | GO:0045917 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.0 | 0.0 | GO:1902276 | pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595) |
| 0.0 | 0.0 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.1 | GO:0044393 | microspike(GO:0044393) |
| 0.0 | 0.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.1 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.0 | 0.0 | GO:0005534 | galactose binding(GO:0005534) |
| 0.0 | 0.0 | GO:0002060 | purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |