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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Meox1

Z-value: 0.50

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Transcription factors associated with Meox1

Gene Symbol Gene ID Gene Info
ENSRNOG00000020803 mesenchyme homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meox1rn6_v1_chr10_-_89816491_898164910.424.8e-01Click!

Activity profile of Meox1 motif

Sorted Z-values of Meox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_123106694 0.71 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr5_+_50381244 0.48 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr1_+_87224677 0.32 ENSRNOT00000028070
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr1_+_80279706 0.16 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr7_-_143353925 0.16 ENSRNOT00000068533
keratin 71
chr2_-_25235275 0.14 ENSRNOT00000061580
F2R like trypsin receptor 1
chr6_+_34155017 0.14 ENSRNOT00000073663
tetratricopeptide repeat domain 32
chr18_-_24735349 0.13 ENSRNOT00000036537
G protein-coupled receptor 17
chr6_-_123577695 0.12 ENSRNOT00000006604
forkhead box N3
chr20_+_40769586 0.12 ENSRNOT00000001079
fatty acid binding protein 7
chr10_-_44746549 0.11 ENSRNOT00000003841
family with sequence similarity 183, member B
chr8_-_78233430 0.11 ENSRNOT00000083220
cingulin-like 1
chr4_-_157304653 0.11 ENSRNOT00000051613
leucine rich repeat containing 23
chr20_-_10013190 0.11 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr9_+_20241062 0.11 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr12_+_47179664 0.11 ENSRNOT00000001551
calcium binding protein 1
chr12_-_13668515 0.10 ENSRNOT00000086847
fascin actin-bundling protein 1
chr17_-_2705123 0.09 ENSRNOT00000024940
olfactory receptor 1652
chr14_-_34218961 0.08 ENSRNOT00000072588
similar to Exocyst complex component 1 (Exocyst complex component Sec3)
chr20_+_31234493 0.08 ENSRNOT00000000675
neuropeptide FF receptor 1
chr5_+_76182121 0.08 ENSRNOT00000020707
G protein subunit gamma 10
chr8_+_126975833 0.08 ENSRNOT00000088348

chr3_-_154627257 0.08 ENSRNOT00000018328
transglutaminase 2
chr2_+_158097843 0.08 ENSRNOT00000016541
pentraxin 3
chr10_-_93675991 0.08 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr20_-_30947484 0.07 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr1_-_154170409 0.07 ENSRNOT00000089014
Hikeshi, heat shock protein nuclear import factor
chrX_-_69218526 0.07 ENSRNOT00000092321
ENSRNOT00000074071
ENSRNOT00000092571
praja ring finger ubiquitin ligase 1
chr5_-_173233188 0.06 ENSRNOT00000055343
transmembrane protein 88B
chr11_-_32550539 0.06 ENSRNOT00000002715
regulator of calcineurin 1
chr1_-_15374850 0.06 ENSRNOT00000016728
peroxisomal biogenesis factor 7
chr3_+_63510293 0.06 ENSRNOT00000058093
deafness, autosomal recessive 59
chr20_-_10013559 0.06 ENSRNOT00000091623
radial spoke head 1 homolog
chrX_+_111396995 0.06 ENSRNOT00000087634
PIH1 domain containing 3
chr1_+_40879747 0.06 ENSRNOT00000083702
A-kinase anchoring protein 12
chr7_-_29171783 0.06 ENSRNOT00000079235
myosin binding protein C, slow type
chr9_-_23493081 0.05 ENSRNOT00000072144
Rh-associated glycoprotein
chr11_-_62067655 0.05 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr3_+_72395218 0.05 ENSRNOT00000057616
proteoglycan 3, pro eosinophil major basic protein 2
chr12_+_22165486 0.05 ENSRNOT00000001890
motile sperm domain containing 3
chr2_+_185846232 0.05 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr6_+_22296128 0.05 ENSRNOT00000087805
dpy-30 histone methyltransferase complex regulatory subunit
chr1_+_89408935 0.05 ENSRNOT00000075068
protein FAM187B-like
chr8_+_87205311 0.05 ENSRNOT00000014449
LRRGT00022-like
chr1_+_248428099 0.05 ENSRNOT00000050984
mannose binding lectin 2
chr18_-_67224566 0.04 ENSRNOT00000064947
DCC netrin 1 receptor
chr12_-_9998779 0.04 ENSRNOT00000001265
ribosomal protein L21
chr7_+_133856101 0.04 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr1_-_67065797 0.04 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr11_-_14304603 0.04 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr14_-_10694164 0.04 ENSRNOT00000080099

chr18_+_51523758 0.04 ENSRNOT00000078518
GRAM domain containing 3
chr3_-_101547478 0.04 ENSRNOT00000006203
fin bud initiation factor homolog (zebrafish)
chr7_-_107203897 0.04 ENSRNOT00000086263
leucine rich repeat containing 6
chr5_+_15043955 0.04 ENSRNOT00000047093
retinitis pigmentosa 1
chrX_-_29556610 0.04 ENSRNOT00000068113
trafficking protein particle complex 2
chr5_-_161981441 0.04 ENSRNOT00000020316
podoplanin
chr1_-_252461461 0.04 ENSRNOT00000026093
ankyrin repeat domain 22
chr4_-_100252755 0.04 ENSRNOT00000017301
vesicle-associated membrane protein 8
chr1_+_88113445 0.04 ENSRNOT00000056955
gametogenetin
chr7_+_72924799 0.04 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr9_-_80167033 0.04 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr12_+_22727335 0.04 ENSRNOT00000077293
zinc finger, HIT-type containing 1
chr4_-_165026414 0.04 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr19_-_49448072 0.03 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr4_+_78458625 0.03 ENSRNOT00000049891
transmembrane protein 176A
chr7_+_2504695 0.03 ENSRNOT00000003965
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_-_145062956 0.03 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr7_-_143497108 0.03 ENSRNOT00000048613
keratin 76
chr8_+_103938520 0.03 ENSRNOT00000067835
glycerol kinase 5 (putative)
chr9_+_92681078 0.03 ENSRNOT00000034152
SP100 nuclear antigen
chr6_+_101532518 0.03 ENSRNOT00000075054
gephyrin
chr15_-_28517335 0.03 ENSRNOT00000060514
ENSRNOT00000090378
heterogeneous nuclear ribonucleoproteins C1/C2-like
chrX_-_123980357 0.03 ENSRNOT00000049435
reproductive homeobox 8
chr2_+_187951344 0.03 ENSRNOT00000027123
signal sequence receptor, beta
chr2_+_208900103 0.03 ENSRNOT00000055966
chitinase 3-like 3
chr11_+_70056624 0.03 ENSRNOT00000002447

chr7_+_120161091 0.03 ENSRNOT00000013764
nucleolar protein 12
chr15_+_27875911 0.03 ENSRNOT00000013582
purine nucleoside phosphorylase
chr11_-_82893845 0.03 ENSRNOT00000075306
eukaryotic translation initiation factor 4 gamma 1-like
chr14_+_88543630 0.03 ENSRNOT00000060515
heterogeneous nuclear ribonucleoprotein C
chr6_+_132510757 0.03 ENSRNOT00000080230
Enah/Vasp-like
chr17_-_54678710 0.03 ENSRNOT00000046013
zinc finger E-box binding homeobox 1
chr1_-_212633304 0.03 ENSRNOT00000025611
olfactory receptor 286
chr7_-_140356209 0.03 ENSRNOT00000077856
Rho family GTPase 1
chr3_-_46942966 0.03 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr4_+_61924013 0.03 ENSRNOT00000090717
bisphosphoglycerate mutase
chr14_+_22517774 0.03 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr8_-_82533689 0.03 ENSRNOT00000014124
tropomodulin 2
chr2_-_158133861 0.03 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr1_+_225037737 0.03 ENSRNOT00000077959
BSCL2, seipin lipid droplet biogenesis associated
chr4_+_55720010 0.03 ENSRNOT00000063987
fascin actin-bundling protein 3
chr1_+_219390523 0.03 ENSRNOT00000054852
G protein-coupled receptor 152
chr3_-_7498555 0.03 ENSRNOT00000017725
BarH-like homeobox 1
chr2_+_80269661 0.02 ENSRNOT00000015975

chr7_+_120153184 0.02 ENSRNOT00000013538
galectin 1
chr1_+_265157379 0.02 ENSRNOT00000022426
beta-transducin repeat containing E3 ubiquitin protein ligase
chr8_+_26432514 0.02 ENSRNOT00000081574
septin 7
chr6_+_124123228 0.02 ENSRNOT00000005329
proteasome 26S subunit, ATPase 1
chr7_-_59882077 0.02 ENSRNOT00000068774
myelin regulatory factor-like
chr1_+_69841998 0.02 ENSRNOT00000072231
zinc finger protein 773, pseudogene 1
chr17_-_43537293 0.02 ENSRNOT00000091749
solute carrier family 17 member 3
chr6_-_127319362 0.02 ENSRNOT00000012256
DEAD-box helicase 24
chr10_+_55492404 0.02 ENSRNOT00000005588
ENSRNOT00000078038
ribosomal protein L26
chr3_-_52849907 0.02 ENSRNOT00000041096
sodium voltage-gated channel alpha subunit 7
chr11_+_43194348 0.02 ENSRNOT00000075303
olfactory receptor 1532
chr15_-_35113678 0.02 ENSRNOT00000059677
cathepsin G
chr15_+_4554603 0.02 ENSRNOT00000075153
potassium two pore domain channel subfamily K member 5
chr13_+_82438697 0.02 ENSRNOT00000003759
selectin P
chr10_+_103956019 0.02 ENSRNOT00000045875
mitochondrial ribosomal protein L58
chr14_-_64476796 0.02 ENSRNOT00000029104
glucosidase, beta, acid 3
chr11_-_69316848 0.02 ENSRNOT00000033420
coiled-coil domain containing 14
chr4_+_70977556 0.02 ENSRNOT00000031984
hypothetical protein LOC680112
chr7_+_144080614 0.02 ENSRNOT00000077687
poly(rC) binding protein 2
chr2_+_22950018 0.02 ENSRNOT00000071804
homer scaffolding protein 1
chr1_+_169590308 0.02 ENSRNOT00000023147
olfactory receptor 155
chrX_-_70835089 0.02 ENSRNOT00000076351
testis expressed 11
chr2_+_178117466 0.02 ENSRNOT00000065115
ENSRNOT00000084198
similar to hypothetical protein FLJ25371
chr2_-_60657712 0.02 ENSRNOT00000040348
retinoic acid induced 14
chr9_-_44419998 0.02 ENSRNOT00000091397
ENSRNOT00000083747
testis specific 10
chr19_-_24614019 0.02 ENSRNOT00000005124
short coiled-coil protein
chr14_+_22375955 0.02 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr10_+_104582955 0.02 ENSRNOT00000009733
unkempt family zinc finger
chr11_+_43143882 0.02 ENSRNOT00000041445
olfactory receptor 1528
chr5_+_64476317 0.02 ENSRNOT00000017217
collagen alpha-1(XV) chain-like
chr10_+_88227360 0.02 ENSRNOT00000041033
eukaryotic translation initiation factor 1
chr1_+_22332090 0.02 ENSRNOT00000091252
trace amine-associated receptor 8c (Taar8c), mRNA
chr3_-_26056818 0.02 ENSRNOT00000044209
LDL receptor related protein 1B
chr1_+_59156251 0.01 ENSRNOT00000017442
limb and CNS expressed 1
chr8_+_44136496 0.01 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr7_-_76294663 0.01 ENSRNOT00000064513
neurocalcin delta
chr2_+_54466280 0.01 ENSRNOT00000033112
complement C6
chr4_+_115416580 0.01 ENSRNOT00000018303
ATPase H+ transporting V1 subunit B1
chr19_-_11263980 0.01 ENSRNOT00000025086
nucleoporin 93
chr4_+_181874861 0.01 ENSRNOT00000002527
coiled-coil domain containing 91
chr14_+_22091777 0.01 ENSRNOT00000072483
sulfotransferase family 1D, member 1
chr8_+_36850324 0.01 ENSRNOT00000060448
prostate and testis expressed 2
chr10_-_110274768 0.01 ENSRNOT00000054931
secreted and transmembrane 1A
chr1_+_255579474 0.01 ENSRNOT00000024465
B-TFIID TATA-box binding protein associated factor 1
chr2_-_219262901 0.01 ENSRNOT00000037068
G-protein coupled receptor 88
chr9_+_71247781 0.01 ENSRNOT00000049654
cAMP responsive element binding protein 1
chr18_-_69780922 0.01 ENSRNOT00000079093
malic enzyme 2
chr17_-_44841382 0.01 ENSRNOT00000080119
histone cluster 1, H2ak
chr1_-_103760913 0.01 ENSRNOT00000049722
MAS-related GPR, member X2
chr5_-_157059508 0.01 ENSRNOT00000022282
von Willebrand factor A domain containing 5B1
chr7_+_380741 0.01 ENSRNOT00000091013
nidogen-2-like
chr18_+_4084228 0.01 ENSRNOT00000071392
calcium binding tyrosine phosphorylation regulated
chr5_-_102743417 0.01 ENSRNOT00000067389
basonuclin 2
chr1_+_273854248 0.01 ENSRNOT00000044827
ENSRNOT00000017600
ENSRNOT00000086496
adducin 3
chr3_-_114251647 0.01 ENSRNOT00000024245
dual oxidase maturation factor 1
chr13_-_89545182 0.01 ENSRNOT00000078402
Purkinje cell protein 4-like 1
chr6_+_22167919 0.01 ENSRNOT00000007655
NLR family, CARD domain containing 4
chr6_-_78549669 0.01 ENSRNOT00000009940
forkhead box A1
chr7_-_36660141 0.01 ENSRNOT00000012363
nudix hydrolase 4
chr3_+_56056925 0.01 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chrX_+_6273733 0.01 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr8_+_22648323 0.01 ENSRNOT00000013165
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr17_+_82430836 0.01 ENSRNOT00000083164
MAM and LDL receptor class A domain containing 1
chr20_-_3751994 0.01 ENSRNOT00000072288
POU class 5 homeobox 1
chrX_+_5825711 0.01 ENSRNOT00000037360
EF-hand domain containing 2
chr1_+_227892956 0.01 ENSRNOT00000028483

chr3_-_72895740 0.01 ENSRNOT00000012568
fatty acid desaturase 2-like 1
chr8_-_87419564 0.01 ENSRNOT00000015365
filamin A interacting protein 1
chr16_-_74496731 0.01 ENSRNOT00000015790
mitochondrial ribosomal protein S31
chr1_+_185863043 0.01 ENSRNOT00000079072
SRY box 6
chr11_+_88376256 0.01 ENSRNOT00000081776
pre-B lymphocyte 1
chr7_-_76488216 0.01 ENSRNOT00000080024
neurocalcin delta
chr3_+_149802621 0.00 ENSRNOT00000071772
similar to Vomeromodulin
chr2_+_145174876 0.00 ENSRNOT00000040631
mab-21 like 1
chr3_-_8348746 0.00 ENSRNOT00000064638
TruB pseudouridine synthase family member 2
chrX_+_66314418 0.00 ENSRNOT00000035405
G protein-coupled receptor 15-like
chr1_-_23556241 0.00 ENSRNOT00000072943
syntaxin-7-like
chr1_+_97777685 0.00 ENSRNOT00000030895
similar to F49E2.5d
chr9_+_98438439 0.00 ENSRNOT00000027220
selenocysteine lyase
chr3_-_21904133 0.00 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr13_+_47935163 0.00 ENSRNOT00000006768
eukaryotic translation initiation factor 2D
chr3_-_37803112 0.00 ENSRNOT00000059461
nebulin
chr3_+_95233874 0.00 ENSRNOT00000079743
hypothetical protein LOC691083
chr1_+_166141954 0.00 ENSRNOT00000042524
FCH and double SH3 domains 2
chr5_+_137257287 0.00 ENSRNOT00000037160
ELOVL fatty acid elongase 1
chr16_+_23553647 0.00 ENSRNOT00000041994
pleckstrin and Sec7 domain containing 3
chr1_-_218810118 0.00 ENSRNOT00000065950
ENSRNOT00000020886
protein phosphatase 6, regulatory subunit 3
chr1_-_84950210 0.00 ENSRNOT00000083050

chr10_-_43931094 0.00 ENSRNOT00000039778
olfactory receptor 1415
chr1_+_163398891 0.00 ENSRNOT00000020513
guanylate cyclase 2E
chr14_-_82658891 0.00 ENSRNOT00000006841
UV-stimulated scaffold protein A

Network of associatons between targets according to the STRING database.

First level regulatory network of Meox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0045575 basophil activation(GO:0045575)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:1902276 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.0 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) urate biosynthetic process(GO:0034418) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones