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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Mef2b

Z-value: 0.33

Motif logo

Transcription factors associated with Mef2b

Gene Symbol Gene ID Gene Info
ENSRNOG00000020400 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2brn6_v1_chr16_-_21017163_210171630.484.1e-01Click!

Activity profile of Mef2b motif

Sorted Z-values of Mef2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_15274917 0.39 ENSRNOT00000019650
progastricsin
chr7_+_142912316 0.27 ENSRNOT00000010171
nuclear receptor subfamily 4, group A, member 1
chr1_+_101178104 0.14 ENSRNOT00000028072
parathyroid hormone 2
chrX_+_13117239 0.13 ENSRNOT00000088998

chr3_-_170040953 0.12 ENSRNOT00000005866
cerebellin 4 precursor
chr2_-_45518502 0.11 ENSRNOT00000014627
heat shock protein family B (small) member 3
chrX_-_40086870 0.09 ENSRNOT00000010027
small muscle protein, X-linked
chr3_+_147358858 0.08 ENSRNOT00000012951
R-spondin 4
chr2_+_196334626 0.08 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr1_+_31531143 0.08 ENSRNOT00000034704
leucine rich repeat containing 14B
chrX_-_13116743 0.08 ENSRNOT00000004305
MID1 interacting protein 1
chr13_+_53283855 0.08 ENSRNOT00000043590
similar to ribosomal protein L31
chr18_+_55505993 0.07 ENSRNOT00000043736
similar to interferon-inducible GTPase
chr17_+_57075218 0.07 ENSRNOT00000089536
cAMP responsive element modulator
chr18_+_55463308 0.06 ENSRNOT00000073388
interferon-inducible GTPase 1-like
chr1_-_199624783 0.06 ENSRNOT00000026908
cytochrome c oxidase subunit 6A2
chr11_-_1983513 0.06 ENSRNOT00000000907
5-hydroxytryptamine receptor 1F
chr3_+_56868167 0.06 ENSRNOT00000087134
glutamate decarboxylase 1
chr2_-_53185926 0.06 ENSRNOT00000081558
growth hormone receptor
chr17_-_389967 0.06 ENSRNOT00000023865
fructose-bisphosphatase 2
chr10_-_70871066 0.06 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr11_+_46184871 0.06 ENSRNOT00000048417
Trk-fused gene
chr5_+_151776004 0.06 ENSRNOT00000009683
nuclear receptor subfamily 0, group B, member 2
chr17_-_43807540 0.06 ENSRNOT00000074763
similar to CG31613-PA
chr1_-_47307488 0.06 ENSRNOT00000090033
ezrin
chr10_+_54352270 0.06 ENSRNOT00000036752
dehydrogenase/reductase 7C
chr10_+_90217924 0.06 ENSRNOT00000028388
ankyrin repeat and SOCS box-containing 16
chr1_-_153752541 0.05 ENSRNOT00000080927
protease, serine, 23
chr5_-_114014277 0.05 ENSRNOT00000011731
Jun proto-oncogene, AP-1 transcription factor subunit
chr9_+_98490608 0.05 ENSRNOT00000027232
kelch-like family member 30
chr5_-_152473868 0.05 ENSRNOT00000022130
family with sequence similarity 110, member D
chr18_-_26211445 0.05 ENSRNOT00000027739
neuronal regeneration related protein
chr4_+_7258176 0.05 ENSRNOT00000061992
transmembrane and ubiquitin-like domain containing 1
chr10_+_3218466 0.05 ENSRNOT00000093629
ENSRNOT00000093338
ENSRNOT00000077695
N-terminal asparagine amidase
chr14_-_17171580 0.05 ENSRNOT00000085525
ADP-ribosyltransferase 3
chr14_-_19072677 0.04 ENSRNOT00000060548
similar to alpha-fetoprotein
chr5_+_145188323 0.04 ENSRNOT00000038888
transmembrane protein 35B
chr1_-_20155960 0.04 ENSRNOT00000061389
sterile alpha motif domain containing 3
chr6_-_60124274 0.04 ENSRNOT00000059823
leucine-rich single-pass membrane protein 1
chr17_+_76002275 0.04 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr2_+_198772937 0.04 ENSRNOT00000028812
integrin subunit alpha 10
chr1_+_80279706 0.04 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr19_+_56272162 0.04 ENSRNOT00000030399
AFG3(ATPase family gene 3)-like 1 (S. cerevisiae)
chr5_-_22769907 0.04 ENSRNOT00000047805
ENSRNOT00000076167
ENSRNOT00000076507
ENSRNOT00000076113
ENSRNOT00000083779
aspartate-beta-hydroxylase
chr1_+_55219773 0.04 ENSRNOT00000041610
similar to putative protein kinase
chr16_+_54386513 0.04 ENSRNOT00000080696

chr3_+_79918969 0.04 ENSRNOT00000016306
Spi-1 proto-oncogene
chr11_-_34526931 0.04 ENSRNOT00000002291
holocarboxylase synthetase
chr4_+_153874852 0.04 ENSRNOT00000079744
solute carrier family 6 member 13
chrM_-_14061 0.04 ENSRNOT00000051268
mitochondrially encoded NADH dehydrogenase 6
chr1_+_169590308 0.04 ENSRNOT00000023147
olfactory receptor 155
chr2_+_185846232 0.03 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr19_+_10731855 0.03 ENSRNOT00000022277
plasmolipin
chr2_-_172361779 0.03 ENSRNOT00000085876
schwannomin interacting protein 1
chr4_+_88328061 0.03 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr5_+_147257678 0.03 ENSRNOT00000066268
ring finger protein 19B
chr4_-_50312608 0.03 ENSRNOT00000010019
Fez family zinc finger 1
chr10_-_43512287 0.03 ENSRNOT00000036481
fatty acid hydroxylase domain containing 2
chr13_-_81214494 0.03 ENSRNOT00000004950
ENSRNOT00000082385
paired related homeobox 1
chr4_+_119680112 0.03 ENSRNOT00000013282
glycoprotein IX (platelet)
chr17_-_43422846 0.03 ENSRNOT00000050526
histone cluster 1 H2A family member a
chr4_-_49422824 0.03 ENSRNOT00000077889
family with sequence similarity 3, member C
chr5_-_64818813 0.03 ENSRNOT00000009111
ENSRNOT00000086505
aldolase, fructose-bisphosphate B
chr12_-_9864791 0.03 ENSRNOT00000073026
general transcription factor III A
chr16_+_51748970 0.03 ENSRNOT00000059182
a disintegrin and metallopeptidase domain 26A
chr17_+_10559680 0.03 ENSRNOT00000023320
NOP16 nucleolar protein
chr3_+_5709236 0.03 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr4_-_157486844 0.03 ENSRNOT00000038281
ENSRNOT00000022874
COP9 signalosome subunit 7A
chr4_+_148782479 0.03 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr17_+_72218769 0.03 ENSRNOT00000041346
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr5_+_116973159 0.03 ENSRNOT00000046475
uncharacterized LOC100912024
chr2_+_204512302 0.03 ENSRNOT00000021846
calsequestrin 2
chr1_+_122981755 0.03 ENSRNOT00000013468
necdin, MAGE family member
chr5_-_17061361 0.03 ENSRNOT00000089318
proenkephalin
chr10_-_4257868 0.03 ENSRNOT00000035886
TNF receptor superfamily member 17
chr15_+_61673560 0.03 ENSRNOT00000093661
mitochondrial translation release factor 1
chr18_+_55391388 0.02 ENSRNOT00000071612
interferon-inducible GTPase 1-like
chr3_-_36660758 0.02 ENSRNOT00000006111
Rho family GTPase 3
chr18_-_67224566 0.02 ENSRNOT00000064947
DCC netrin 1 receptor
chr5_+_147476221 0.02 ENSRNOT00000010730
syncoilin, intermediate filament protein
chr13_-_72063347 0.02 ENSRNOT00000090544
ENSRNOT00000003869
calcium voltage-gated channel subunit alpha1 E
chr3_+_150323116 0.02 ENSRNOT00000023429
ENSRNOT00000080485
RALY heterogeneous nuclear ribonucleoprotein
chr13_+_90692666 0.02 ENSRNOT00000010028
immunoglobulin superfamily, member 8
chr14_-_21748356 0.02 ENSRNOT00000002670
calcium binding protein, spermatid associated 1
chr1_-_199270627 0.02 ENSRNOT00000026063
syntaxin 1B
chr15_+_17834635 0.02 ENSRNOT00000085530
similar to RIKEN cDNA 4933406L09
chr12_+_41600005 0.02 ENSRNOT00000001872
phospholipase B domain containing 2
chr10_-_56591364 0.02 ENSRNOT00000032481
elongator acetyltransferase complex subunit 5
chr4_-_164049599 0.02 ENSRNOT00000078267

chr2_+_188784222 0.02 ENSRNOT00000028095
phosphomevalonate kinase
chr1_+_101324652 0.02 ENSRNOT00000028116
histidine rich calcium binding protein
chr4_+_88271061 0.02 ENSRNOT00000087374
vomeronasal 1 receptor 86
chr2_+_256964860 0.02 ENSRNOT00000073547
interferon-induced protein 44-like
chr6_+_107460668 0.02 ENSRNOT00000013515
acyl-CoA thioesterase 2
chr18_+_61563053 0.02 ENSRNOT00000022845
gastrin releasing peptide
chr9_-_50820290 0.02 ENSRNOT00000050748
uncharacterized LOC102548013
chr15_+_19603288 0.02 ENSRNOT00000035491
REST corepressor 2-like
chr6_-_108120579 0.02 ENSRNOT00000041163
ectonucleoside triphosphate diphosphohydrolase 5
chr16_+_49266903 0.02 ENSRNOT00000014704
solute carrier family 25 member 4
chr2_-_261337163 0.02 ENSRNOT00000030341
TNNI3 interacting kinase
chrX_+_33895769 0.02 ENSRNOT00000085993
ENSRNOT00000079365
RALBP1 associated Eps domain containing protein 2
chr10_+_82032656 0.02 ENSRNOT00000067751
ankyrin repeat domain 40
chr3_+_43271596 0.02 ENSRNOT00000088589
glycerol-3-phosphate dehydrogenase 2
chr1_-_253186695 0.02 ENSRNOT00000080928

chrX_-_62690806 0.02 ENSRNOT00000018147
DNA polymerase alpha 1, catalytic subunit
chr2_-_216443518 0.02 ENSRNOT00000022496
amylase, alpha 1A
chr19_+_9622611 0.02 ENSRNOT00000061498
solute carrier family 38, member 7
chr13_-_90602365 0.02 ENSRNOT00000009344
calsequestrin 1
chr1_-_224921092 0.02 ENSRNOT00000025196
solute carrier family 3 member 2
chr1_+_15180328 0.02 ENSRNOT00000050656
interleukin 20 receptor subunit alpha
chr16_+_2537248 0.02 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr11_-_14304603 0.02 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_-_61470348 0.02 ENSRNOT00000083841
N-alpha-acetyltransferase 50-like
chr13_+_67545430 0.02 ENSRNOT00000003405
phosducin
chr6_+_132246602 0.02 ENSRNOT00000009896
cytochrome P450, family 46, subfamily a, polypeptide 1
chr2_+_198721724 0.02 ENSRNOT00000043535
ankyrin repeat domain 34A
chr9_-_50762082 0.01 ENSRNOT00000015492
methyltransferase like 21C
chr18_-_74688551 0.01 ENSRNOT00000078016
solute carrier family 14 member 2
chr13_+_92264231 0.01 ENSRNOT00000066509
ENSRNOT00000004716
spectrin, alpha, erythrocytic 1
chr6_-_136550371 0.01 ENSRNOT00000065971
retinal degeneration 3-like
chr13_-_77896697 0.01 ENSRNOT00000003452
tenascin N
chr2_+_208541361 0.01 ENSRNOT00000021288
transmembrane and immunoglobulin domain containing 3
chr4_-_81241152 0.01 ENSRNOT00000015325
ENSRNOT00000015152
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_-_101138427 0.01 ENSRNOT00000058615
Fras1 related extracellular matrix 1
chr9_+_71247781 0.01 ENSRNOT00000049654
cAMP responsive element binding protein 1
chr8_+_110982777 0.01 ENSRNOT00000010992
kyphoscoliosis peptidase
chr10_+_77755216 0.01 ENSRNOT00000087765
monocyte to macrophage differentiation-associated
chr2_-_5577369 0.01 ENSRNOT00000093420
nuclear receptor subfamily 2, group F, member 1
chr7_-_104486710 0.01 ENSRNOT00000084764
gasdermin C
chr15_-_65507968 0.01 ENSRNOT00000046240
calmodulin 2
chr1_+_84411726 0.01 ENSRNOT00000025303
AKT serine/threonine kinase 2
chr15_-_37325178 0.01 ENSRNOT00000011699
gap junction protein, alpha 3
chr8_+_1459526 0.01 ENSRNOT00000034503
kelch repeat and BTB domain containing 3
chr20_+_20577561 0.01 ENSRNOT00000081113
cyclin-dependent kinase 1
chr6_-_136145837 0.01 ENSRNOT00000015122
creatine kinase B
chr15_-_28314459 0.01 ENSRNOT00000042055
ENSRNOT00000040540
NDRG family member 2
chr18_+_35574002 0.01 ENSRNOT00000093442
ENSRNOT00000070817
ENSRNOT00000093356
myotilin
chr1_-_259287684 0.01 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr12_-_29952196 0.01 ENSRNOT00000086175
transmembrane protein 248
chrX_-_136150209 0.01 ENSRNOT00000048498
ecto-NOX disulfide-thiol exchanger 2
chr3_+_56056925 0.01 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr8_+_22750336 0.01 ENSRNOT00000013496
low density lipoprotein receptor
chrX_-_62698830 0.01 ENSRNOT00000076359
DNA polymerase alpha 1, catalytic subunit
chr15_-_45550285 0.01 ENSRNOT00000012948
guanylate cyclase 1 soluble subunit beta 2
chr4_-_23718047 0.01 ENSRNOT00000011359
similar to RIKEN cDNA 4921511H03
chr5_+_154598758 0.01 ENSRNOT00000015776
transcription elongation factor A3
chr3_-_14112851 0.01 ENSRNOT00000092736
complement C5
chr13_-_30800451 0.01 ENSRNOT00000046791
ribosomal protein L21
chr5_+_135442031 0.01 ENSRNOT00000090852
ENSRNOT00000034464
coiled-coil domain containing 17
chr1_-_56683731 0.01 ENSRNOT00000014552
thrombospondin 2
chr2_+_226563050 0.01 ENSRNOT00000065111
breast cancer anti-estrogen resistance 3
chr17_-_10559627 0.01 ENSRNOT00000023515
HIG1 hypoxia inducible domain family, member 2A
chr9_+_37727942 0.01 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr10_+_89459650 0.01 ENSRNOT00000028149
ENSRNOT00000077942
NBR1, autophagy cargo receptor
chr6_+_29061618 0.01 ENSRNOT00000092223
ATPase family, AAA domain containing 2B
chr5_+_15043955 0.01 ENSRNOT00000047093
retinitis pigmentosa 1
chr9_+_118586179 0.01 ENSRNOT00000022351
DLG associated protein 1
chr1_-_64090017 0.01 ENSRNOT00000086622
ENSRNOT00000091654
ribosomal protein S9
chr8_-_132919110 0.01 ENSRNOT00000008747
X-C motif chemokine receptor 1
chr16_-_31301880 0.01 ENSRNOT00000084847
ENSRNOT00000083943

chr10_+_34383396 0.01 ENSRNOT00000047186
olfactory receptor 1386
chr5_+_33097654 0.01 ENSRNOT00000008087
cyclic nucleotide gated channel beta 3
chrX_-_64726210 0.01 ENSRNOT00000076012
ENSRNOT00000086265
ankyrin repeat and SOCS box-containing 12
chr13_-_84694575 0.01 ENSRNOT00000066609
flavin-containing monooxygenase 13
chr3_+_72063504 0.01 ENSRNOT00000066606
BTB domain containing 18
chr1_+_218945508 0.01 ENSRNOT00000034240
similar to RIKEN cDNA 1810055G02
chr17_-_27279260 0.01 ENSRNOT00000018508
small nuclear ribonucleoprotein U11/U12 subunit 48
chr10_-_25847994 0.01 ENSRNOT00000082076
methionine adenosyltransferase 2B
chrX_-_104814145 0.01 ENSRNOT00000004909
synaptotagmin-like 4
chr1_-_166912524 0.01 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr7_+_40316639 0.00 ENSRNOT00000080150
similar to hypothetical protein FLJ35821
chrX_-_135041027 0.00 ENSRNOT00000006484
zinc finger, DHHC-type containing 9
chr12_+_30655898 0.00 ENSRNOT00000079144
zinc finger protein 11
chr1_-_64350338 0.00 ENSRNOT00000078444
calcium voltage-gated channel auxiliary subunit gamma 8
chr2_+_198655437 0.00 ENSRNOT00000028781
hemochromatosis type 2 (juvenile)
chr17_-_47394231 0.00 ENSRNOT00000079368
ENSRNOT00000079216
secreted frizzled-related protein 4
chr14_-_72025137 0.00 ENSRNOT00000080604
C1q and tumor necrosis factor related protein 7
chr13_+_93751759 0.00 ENSRNOT00000065706
WD repeat domain 64
chr1_-_217902473 0.00 ENSRNOT00000028329
anoctamin 1
chr7_-_107391184 0.00 ENSRNOT00000056793
transmembrane protein 71
chr1_+_167944448 0.00 ENSRNOT00000087667
olfactory receptor 56
chr10_-_71439540 0.00 ENSRNOT00000087769
transcriptional adaptor 2A
chr8_+_117062884 0.00 ENSRNOT00000082452
ENSRNOT00000071540
nicolin 1
chr4_-_62840357 0.00 ENSRNOT00000059892
solute carrier family 13 member 4
chr10_-_15459897 0.00 ENSRNOT00000027518
2,4-dienoyl-CoA reductase 2
chr13_-_80819218 0.00 ENSRNOT00000072922
flavin containing monooxygenase 6
chr17_+_18031228 0.00 ENSRNOT00000081708
thiopurine S-methyltransferase
chr2_+_119197239 0.00 ENSRNOT00000048030
ubiquitin specific peptidase 13
chr10_-_51576376 0.00 ENSRNOT00000004829
Rho GTPase activating protein 44
chr15_+_42653148 0.00 ENSRNOT00000022095
clusterin
chr9_+_88110731 0.00 ENSRNOT00000088677
rhomboid domain containing 1
chr9_-_63641400 0.00 ENSRNOT00000087684
SATB homeobox 2
chr3_-_173944396 0.00 ENSRNOT00000079019
synaptonemal complex protein 2
chr1_+_78800754 0.00 ENSRNOT00000084601
dishevelled-binding antagonist of beta-catenin 3
chr15_+_39779648 0.00 ENSRNOT00000084505
calcium binding protein 39-like
chr18_+_28594892 0.00 ENSRNOT00000067702
ubiquitin-conjugating enzyme E2D 2
chr18_-_31082101 0.00 ENSRNOT00000084735
ENSRNOT00000060417
histone deacetylase 3
chr5_+_58995249 0.00 ENSRNOT00000023411
coiled-coil domain containing 107
chr15_+_50891127 0.00 ENSRNOT00000020728
stanniocalcin 1
chrX_+_65566047 0.00 ENSRNOT00000092103
hephaestin

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0035878 nail development(GO:0035878)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0044393 TCR signalosome(GO:0036398) microspike(GO:0044393)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)