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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Mecom

Z-value: 0.26

Motif logo

Transcription factors associated with Mecom

Gene Symbol Gene ID Gene Info
ENSRNOG00000012645 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mecomrn6_v1_chr2_-_117454769_117454769-0.484.2e-01Click!

Activity profile of Mecom motif

Sorted Z-values of Mecom motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_50381244 0.11 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr1_-_20155960 0.07 ENSRNOT00000061389
sterile alpha motif domain containing 3
chr8_+_14060394 0.06 ENSRNOT00000014827
single-pass membrane protein with coiled-coil domains 4
chr5_+_173148884 0.06 ENSRNOT00000041753
hCG1994130-like
chr16_+_75966352 0.05 ENSRNOT00000022774
angiopoietin 2
chr2_-_77784522 0.05 ENSRNOT00000030328
similar to RIKEN cDNA 0610040D20
chr17_+_11101306 0.05 ENSRNOT00000030893
dopamine receptor D1
chr8_+_71514281 0.05 ENSRNOT00000022256
NS5A (hepatitis C virus) transactivated protein 9
chr16_-_82439441 0.05 ENSRNOT00000040315

chr2_-_256154584 0.05 ENSRNOT00000072487

chr1_+_93242050 0.04 ENSRNOT00000013741
similar to 60S ribosomal protein L27a
chr7_+_12471824 0.04 ENSRNOT00000068197
strawberry notch homolog 2
chr6_+_99356509 0.03 ENSRNOT00000008416
A-kinase anchoring protein 5
chr1_+_42121636 0.03 ENSRNOT00000025616
myc target 1
chr10_-_66873948 0.03 ENSRNOT00000039261
ecotropic viral integration site 2A
chr9_-_76768770 0.03 ENSRNOT00000087779
ENSRNOT00000057849
IKAROS family zinc finger 2
chr3_-_148312420 0.03 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2-like 1
chr13_-_107831014 0.03 ENSRNOT00000003684
potassium two pore domain channel subfamily K member 2
chr3_-_107760550 0.03 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr11_+_64601029 0.02 ENSRNOT00000004138
Rho GTPase activating protein 31
chr3_-_44177689 0.02 ENSRNOT00000006387
cytohesin 1 interacting protein
chr4_-_131694755 0.02 ENSRNOT00000013271
forkhead box P1
chr5_+_154265097 0.02 ENSRNOT00000012342
cannabinoid receptor 2
chr9_-_26932201 0.02 ENSRNOT00000017081
minichromosome maintenance complex component 3
chr12_+_41636994 0.01 ENSRNOT00000001882
serine dehydratase-like
chr14_+_63095720 0.01 ENSRNOT00000006071
PPARG coactivator 1 alpha
chr10_+_57251253 0.01 ENSRNOT00000043171
60S ribosomal protein L36a
chr1_-_167765552 0.01 ENSRNOT00000024954
Bcl2-like 1, pseudogene 1
chr11_+_44877859 0.01 ENSRNOT00000060838
collagen type VIII alpha 1 chain
chr2_-_196582997 0.01 ENSRNOT00000081672

chr20_+_1787174 0.01 ENSRNOT00000072824
ENSRNOT00000041883
olfactory receptor 1738
chr5_+_69851171 0.01 ENSRNOT00000047780

chr1_-_93949187 0.01 ENSRNOT00000018956
zinc finger protein 536
chr1_+_128924966 0.01 ENSRNOT00000019267
insulin-like growth factor 1 receptor
chr2_-_3124543 0.01 ENSRNOT00000036547
family with sequence similarity 81, member B
chr4_-_58250798 0.01 ENSRNOT00000048436
Kruppel-like factor 14
chr13_+_89826254 0.01 ENSRNOT00000006141
F11 receptor
chr2_-_187786700 0.01 ENSRNOT00000092257
ENSRNOT00000092612
ENSRNOT00000068360
solute carrier family 25, member 44
chr19_+_38846201 0.01 ENSRNOT00000030768
ENSRNOT00000063977
transport and golgi organization 6 homolog
chr15_-_27726646 0.01 ENSRNOT00000082139
cyclin B1 interacting protein 1
chr8_+_113603533 0.01 ENSRNOT00000017280
mitochondrial ribosomal protein L3
chrX_+_21696772 0.01 ENSRNOT00000043559
hydroxysteroid (17-beta) dehydrogenase 10
chr4_+_142780987 0.01 ENSRNOT00000056570
glutamate metabotropic receptor 7
chr3_-_4341771 0.00 ENSRNOT00000034694
similar to ribosomal protein S13
chr11_+_60383431 0.00 ENSRNOT00000093295
Cd200 molecule
chr13_-_35048444 0.00 ENSRNOT00000009963
GLI family zinc finger 2
chr18_-_5314511 0.00 ENSRNOT00000022637
ENSRNOT00000079682
zinc finger protein 521
chr19_-_38344845 0.00 ENSRNOT00000072666

chr10_+_34519790 0.00 ENSRNOT00000052360
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_-_12330929 0.00 ENSRNOT00000001336
brain protein I3
chr4_+_52147641 0.00 ENSRNOT00000009458
hyaluronoglucosaminidase 4
chr5_-_77408323 0.00 ENSRNOT00000046857
ENSRNOT00000046760
alpha-2u globulin PGCL5
major urinary protein 4
chr17_+_15852548 0.00 ENSRNOT00000022203
caspase recruitment domain family, member 19
chr3_+_260653 0.00 ENSRNOT00000006710

chr8_-_109560747 0.00 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr7_-_124172979 0.00 ENSRNOT00000074960
ADP-ribosylation factor GTPase activating protein 3
chr7_+_97559841 0.00 ENSRNOT00000007326
zinc fingers and homeoboxes 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.0 GO:0071348 cellular response to interleukin-11(GO:0071348)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones