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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Mbd2
Z-value: 0.57
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Transcription factors associated with Mbd2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mbd2 | rn6_v1_chr18_+_65814026_65814026 | 0.50 | 3.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_78902063 Show fit | 0.35 |
ENSRNOT00000088469
|
protein phosphatase 2, regulatory subunit B, gamma |
|
| chr10_+_85301875 Show fit | 0.34 |
ENSRNOT00000080935
|
suppressor of cytokine signaling 7 |
|
| chr6_-_109162267 Show fit | 0.27 |
ENSRNOT00000077518
|
NIMA-related kinase 9 |
|
| chr1_-_267245636 Show fit | 0.24 |
ENSRNOT00000082799
|
SH3 and PX domains 2A |
|
| chr6_-_27190126 Show fit | 0.22 |
ENSRNOT00000068412
ENSRNOT00000013107 |
potassium two pore domain channel subfamily K member 3 |
|
| chr3_-_164095878 Show fit | 0.22 |
ENSRNOT00000079414
|
beta-1,4-galactosyltransferase 5 |
|
| chr16_+_19051965 Show fit | 0.21 |
ENSRNOT00000016399
|
solute carrier family 35, member E1 |
|
| chr19_-_53688597 Show fit | 0.20 |
ENSRNOT00000074448
|
zinc finger CCHC-type containing 14 |
|
| chr15_+_108908607 Show fit | 0.20 |
ENSRNOT00000089455
|
Zic family member 2 |
|
| chr8_+_117486083 Show fit | 0.19 |
ENSRNOT00000027552
ENSRNOT00000088705 |
protein kinase cAMP-dependent type 2 regulatory subunit alpha |
Network of associatons between targets according to the STRING database.
First level regulatory network of Mbd2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.3 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.1 | 0.2 | GO:1900095 | random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.0 | 0.2 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.0 | 0.2 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.0 | 0.2 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.0 | 0.2 | GO:1904717 | regulation of AMPA glutamate receptor clustering(GO:1904717) |
| 0.0 | 0.2 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.0 | 0.2 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 0.1 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.2 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 0.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.2 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.0 | 0.1 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.0 | 0.1 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.0 | 0.1 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.0 | 0.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 0.1 | GO:0051766 | inositol trisphosphate kinase activity(GO:0051766) |
| 0.0 | 0.0 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.2 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |