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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Mafb
Z-value: 0.71
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Transcription factors associated with Mafb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mafb | rn6_v1_chr3_-_156340913_156340913 | -0.75 | 1.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_50404550 Show fit | 0.19 |
ENSRNOT00000073072
|
crystallin, beta B1 |
|
| chr2_-_199479309 Show fit | 0.17 |
ENSRNOT00000042661
|
ribosomal protein L38 |
|
| chrX_+_13441558 Show fit | 0.17 |
ENSRNOT00000030170
|
similar to Ferritin light chain (Ferritin L subunit) |
|
| chrX_+_136460215 Show fit | 0.17 |
ENSRNOT00000093538
|
Rho GTPase activating protein 36 |
|
| chr14_-_21709084 Show fit | 0.17 |
ENSRNOT00000087477
|
submaxillary gland androgen regulated protein 3B |
|
| chr6_+_86131242 Show fit | 0.16 |
ENSRNOT00000039337
|
FAU, ubiquitin like and ribosomal protein S30 fusion |
|
| chr5_+_16845631 Show fit | 0.16 |
ENSRNOT00000047889
|
coiled-coil-helix-coiled-coil-helix domain containing 7 |
|
| chr1_-_103323476 Show fit | 0.16 |
ENSRNOT00000019051
|
MAS related GPR family member X3 |
|
| chr8_-_40883880 Show fit | 0.15 |
ENSRNOT00000075593
|
disks large homolog 5-like |
|
| chr2_-_14701903 Show fit | 0.15 |
ENSRNOT00000051895
|
cytochrome c oxidase subunit 7C |
Network of associatons between targets according to the STRING database.
First level regulatory network of Mafb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0055073 | cadmium ion homeostasis(GO:0055073) |
| 0.0 | 0.2 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.0 | 0.2 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 0.1 | GO:0035566 | regulation of metanephros size(GO:0035566) |
| 0.0 | 0.1 | GO:0007571 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.0 | 0.1 | GO:0001788 | antibody-dependent cellular cytotoxicity(GO:0001788) |
| 0.0 | 0.1 | GO:0071038 | nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049) |
| 0.0 | 0.1 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.0 | 0.1 | GO:0002465 | peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of interferon-gamma biosynthetic process(GO:0045077) |
| 0.0 | 0.1 | GO:1904815 | negative regulation of histone phosphorylation(GO:0033128) negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.2 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.1 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.1 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.1 | GO:0001740 | Barr body(GO:0001740) |
| 0.0 | 0.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.1 | GO:0071547 | piP-body(GO:0071547) |
| 0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.2 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.0 | 0.2 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.0 | 0.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.2 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.1 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.0 | 0.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.0 | 0.1 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.1 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.1 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |