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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Mafa

Z-value: 0.40

Motif logo

Transcription factors associated with Mafa

Gene Symbol Gene ID Gene Info
ENSRNOG00000007668 MAF bZIP transcription factor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafarn6_v1_chr7_-_116781766_116781766-0.247.0e-01Click!

Activity profile of Mafa motif

Sorted Z-values of Mafa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_145931583 0.17 ENSRNOT00000016433
cilia and flagella associated protein 161
chr10_+_14828597 0.16 ENSRNOT00000025434
tektin 4
chr15_+_50891127 0.13 ENSRNOT00000020728
stanniocalcin 1
chrX_-_111102464 0.13 ENSRNOT00000084176
ripply transcriptional repressor 1
chr10_-_46145548 0.12 ENSRNOT00000033483
phospholipase D family, member 6
chr20_-_12938891 0.12 ENSRNOT00000017141
similar to Protein C21orf58
chr2_-_187160373 0.10 ENSRNOT00000018961
neurotrophic receptor tyrosine kinase 1
chr15_-_61873406 0.09 ENSRNOT00000045115
LRRGT00053-like
chr6_+_102392828 0.09 ENSRNOT00000089162
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr1_-_254735548 0.09 ENSRNOT00000025258
ankyrin repeat domain 1
chr1_-_215858034 0.08 ENSRNOT00000027656
insulin 2
chr8_-_48774898 0.08 ENSRNOT00000016303
uroplakin 2
chr10_+_94170766 0.07 ENSRNOT00000010627
angiotensin I converting enzyme
chr5_+_3955227 0.07 ENSRNOT00000009908
musculin
chr1_-_197770669 0.07 ENSRNOT00000023563
linker for activation of T cells
chr1_+_245237736 0.06 ENSRNOT00000035814
very low density lipoprotein receptor
chr8_+_32018560 0.06 ENSRNOT00000007358
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr20_+_10438444 0.06 ENSRNOT00000071248
ENSRNOT00000075545
crystallin, alpha A
chr8_-_58542844 0.06 ENSRNOT00000012041
ELMO domain containing 1
chr20_-_7930929 0.06 ENSRNOT00000000607
TEA domain transcription factor 3
chr2_-_26870421 0.05 ENSRNOT00000088791

chr1_-_224974203 0.05 ENSRNOT00000065694
transmembrane protein 179B
chr2_-_27949066 0.05 ENSRNOT00000081472
ENSRNOT00000022138
NSA2 ribosome biogenesis homolog
chr10_+_83081168 0.05 ENSRNOT00000035023
tachykinin 4 (hemokinin)
chr3_-_60813869 0.05 ENSRNOT00000058234
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr11_+_17538063 0.05 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr15_+_45834302 0.05 ENSRNOT00000051307
serpin family E member 3
chr8_-_107602263 0.04 ENSRNOT00000017658
extended synaptotagmin 3
chrX_+_123913072 0.04 ENSRNOT00000071376
reproductive homeobox 5
chr5_+_26493212 0.04 ENSRNOT00000061328
triple QxxK/R motif containing
chr1_-_87221826 0.04 ENSRNOT00000046611
ENSRNOT00000028006
serine peptidase inhibitor, Kunitz type, 2
chr10_+_73333119 0.04 ENSRNOT00000004736
T-box 4
chr3_-_117766120 0.04 ENSRNOT00000056022
fibrillin 1
chrX_+_17823554 0.04 ENSRNOT00000004118
myc-like oncogene, s-myc protein
chr19_-_37525762 0.04 ENSRNOT00000023606
ATPase H+ transporting V0 subunit D1
chr19_-_11341863 0.03 ENSRNOT00000025694
metallothionein 4
chr4_+_7282948 0.03 ENSRNOT00000011052
cyclin-dependent kinase 5
chr18_+_65814026 0.03 ENSRNOT00000016112
methyl-CpG binding domain protein 2
chr3_-_7203420 0.03 ENSRNOT00000015236
growth factor independent 1B transcriptional repressor
chr6_-_12554439 0.03 ENSRNOT00000022481
luteinizing hormone/choriogonadotropin receptor
chr20_-_11556312 0.03 ENSRNOT00000091856
similar to chromosome 21 open reading frame 29
chr15_+_61873056 0.03 ENSRNOT00000017086
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr1_-_101741441 0.03 ENSRNOT00000028570
sulfotransferase family 2B member 1
chrX_-_10413984 0.03 ENSRNOT00000039551
ENSRNOT00000091448
DEAD-box helicase 3, X-linked
chr17_-_15478343 0.03 ENSRNOT00000078029
osteomodulin
chrX_-_115908693 0.03 ENSRNOT00000091423
transient receptor potential cation channel, subfamily C, member 5
chr20_-_21689553 0.03 ENSRNOT00000038095
transmembrane protein 26
chr17_-_14637832 0.03 ENSRNOT00000074323
osteomodulin
chr8_+_132828091 0.02 ENSRNOT00000008269
C-C motif chemokine receptor 9
chr7_+_4951747 0.02 ENSRNOT00000061482

chr13_-_74276964 0.02 ENSRNOT00000005726
torsin family 3, member A
chr1_-_52495582 0.02 ENSRNOT00000067142
phosphodiesterase 10A
chrX_+_156911345 0.02 ENSRNOT00000080945
L1 cell adhesion molecule
chrX_-_62903530 0.02 ENSRNOT00000076652
ENSRNOT00000017370
pyruvate dehydrogenase kinase 3
chr9_-_65693822 0.02 ENSRNOT00000038431
amyotrophic lateral sclerosis 2 chromosome region, candidate 12
chr4_-_144318580 0.02 ENSRNOT00000007591
ssu-2 homolog
chr13_-_25262469 0.02 ENSRNOT00000019921
ring finger protein 152
chr18_+_30172740 0.02 ENSRNOT00000027340
protocadherin alpha 4
chr18_+_44810388 0.02 ENSRNOT00000021646
ENSRNOT00000089750
hydroxysteroid (17-beta) dehydrogenase 4
chr1_-_167210919 0.01 ENSRNOT00000027507
cholinergic receptor nicotinic alpha 10 subunit
chr13_+_63526486 0.01 ENSRNOT00000003788
BMP/retinoic acid inducible neural specific 3
chr10_+_53818818 0.01 ENSRNOT00000057260
myosin heavy chain 8
chr10_+_89174684 0.01 ENSRNOT00000043754
vacuolar protein sorting 25
chr9_+_16543688 0.01 ENSRNOT00000021868
canopy FGF signaling regulator 3
chr5_-_13097341 0.01 ENSRNOT00000061884
RB1-inducible coiled-coil 1
chrX_+_105134498 0.01 ENSRNOT00000002058
transmembrane protein 35
chr12_+_11215886 0.01 ENSRNOT00000076896
ENSRNOT00000060924
pentatricopeptide repeat domain 1
chr9_-_45505767 0.01 ENSRNOT00000033964
LON peptidase N-terminal domain and ring finger 2
chr3_+_171213936 0.01 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr14_+_114126943 0.01 ENSRNOT00000041638
ENSRNOT00000006443
ENSRNOT00000006957
reticulon 4
chr1_-_213987053 0.01 ENSRNOT00000072774
p53-induced protein with a death domain-like
chr12_-_22726982 0.01 ENSRNOT00000001921
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr7_-_124423832 0.01 ENSRNOT00000013994
malonyl-CoA-acyl carrier protein transacylase
chr4_+_57715946 0.00 ENSRNOT00000079059
ENSRNOT00000034429
kelch domain containing 10
chr1_+_199225100 0.00 ENSRNOT00000088606
SET domain containing 1A
chr10_+_89181180 0.00 ENSRNOT00000078931
ENSRNOT00000027770
WNK lysine deficient protein kinase 4
chr1_-_225128740 0.00 ENSRNOT00000026897
retinal outer segment membrane protein 1
chr12_+_46615649 0.00 ENSRNOT00000086531
ENSRNOT00000089494
BICD family like cargo adaptor 1
chr5_-_58113553 0.00 ENSRNOT00000046589
AT-rich interaction domain 3C
chr10_-_88677055 0.00 ENSRNOT00000025590
GH3 domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1903596 regulation of gap junction assembly(GO:1903596)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.0 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)