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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Maf_Nrl

Z-value: 0.35

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Transcription factors associated with Maf_Nrl

Gene Symbol Gene ID Gene Info
ENSRNOG00000012428 MAF bZIP transcription factor
ENSRNOG00000018528 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafrn6_v1_chr19_-_48196748_48196748-0.829.0e-02Click!
Nrlrn6_v1_chr15_-_34198921_341989210.079.1e-01Click!

Activity profile of Maf_Nrl motif

Sorted Z-values of Maf_Nrl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_73948583 0.24 ENSRNOT00000018097
myosin, light chain 1
chr5_-_153924896 0.24 ENSRNOT00000065247
grainyhead-like transcription factor 3
chr2_-_113616766 0.13 ENSRNOT00000016858
ENSRNOT00000074723
transmembrane protein 212
chr15_-_32888095 0.12 ENSRNOT00000012233
defender against cell death 1
chr20_-_5163247 0.11 ENSRNOT00000001135
allograft inflammatory factor 1
chrX_+_128897181 0.11 ENSRNOT00000008444
SH2 domain containing 1A
chr2_-_28799266 0.10 ENSRNOT00000089293
transmembrane protein 171
chrX_-_32153794 0.09 ENSRNOT00000005348
transmembrane protein 27
chr1_+_276659542 0.08 ENSRNOT00000019681
transcription factor 7 like 2
chr9_+_45605552 0.08 ENSRNOT00000059587
neuromedin S
chr12_+_50407843 0.08 ENSRNOT00000073763
crystallin, beta A4
chr17_-_389967 0.07 ENSRNOT00000023865
fructose-bisphosphatase 2
chr6_+_10533151 0.07 ENSRNOT00000020822
ras homolog family member Q
chr3_+_65815080 0.07 ENSRNOT00000006429
ubiquitin-conjugating enzyme E2E 3
chr10_+_71202456 0.06 ENSRNOT00000076893
HNF1 homeobox B
chr20_+_10438444 0.06 ENSRNOT00000071248
ENSRNOT00000075545
crystallin, alpha A
chr10_-_6870011 0.06 ENSRNOT00000003439
similar to CG4768-PA
chr3_+_112242270 0.06 ENSRNOT00000080533
ENSRNOT00000082876
calpain 3
chr6_+_73345392 0.06 ENSRNOT00000088378
Rho GTPase activating protein 5
chr1_+_32199810 0.06 ENSRNOT00000036714
solute carrier family 6 member 19
chr10_+_55924938 0.05 ENSRNOT00000087003
ENSRNOT00000057079
trafficking protein particle complex 1
chr11_-_28527890 0.05 ENSRNOT00000002138
claudin 8
chr4_+_70828894 0.05 ENSRNOT00000064892
T cell receptor beta, constant 2
chr5_+_124300477 0.05 ENSRNOT00000010100
complement C8 beta chain
chr4_-_67610710 0.05 ENSRNOT00000039067
mitochondrial ribosomal protein S33
chr9_-_73958480 0.05 ENSRNOT00000017838
myosin, light chain 1
chr16_+_83358116 0.05 ENSRNOT00000031109
RAB20, member RAS oncogene family
chr3_-_173839433 0.05 ENSRNOT00000075547

chr8_+_94693290 0.04 ENSRNOT00000013908
cytochrome b5 reductase 4
chr5_+_128881062 0.04 ENSRNOT00000057216
calreticulin 4
chr6_+_136358057 0.04 ENSRNOT00000092741
kinesin light chain 1
chr1_-_175676699 0.04 ENSRNOT00000030474
lymphatic vessel endothelial hyaluronan receptor 1
chr16_+_26906716 0.04 ENSRNOT00000064297
carboxypeptidase E
chr20_+_3744395 0.04 ENSRNOT00000086065
transcription factor 19
chr17_-_16695126 0.04 ENSRNOT00000021550
inhibitor of DNA binding 4, HLH protein
chr3_-_45210474 0.04 ENSRNOT00000091777
coiled-coil domain containing 148
chr7_-_96464049 0.04 ENSRNOT00000006517
hyaluronan synthase 2
chrX_+_35869538 0.04 ENSRNOT00000058947
protein phosphatase with EF-hand domain 1
chr20_+_34258791 0.04 ENSRNOT00000000468
solute carrier family 35, member F1
chr3_+_57770948 0.04 ENSRNOT00000038429

chr9_-_16934714 0.04 ENSRNOT00000061503
cysteine-rich protein 3
chr14_+_33010300 0.04 ENSRNOT00000002809
insulin-like growth factor binding protein 7
chr4_-_178168690 0.03 ENSRNOT00000020729
SRY box 5
chrX_-_23139694 0.03 ENSRNOT00000033656
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_-_8432195 0.03 ENSRNOT00000089800
Rho GTPase activating protein 24
chr11_+_17538063 0.03 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr10_-_88152064 0.03 ENSRNOT00000019477
keratin 16
chrX_-_138435391 0.03 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chr4_+_176994129 0.03 ENSRNOT00000018734
cytidine monophosphate N-acetylneuraminic acid synthetase
chr12_+_19680712 0.03 ENSRNOT00000081310

chr10_+_97647111 0.03 ENSRNOT00000055062
G protein subunit alpha 13
chr13_-_42885440 0.03 ENSRNOT00000038020
NCK-associated protein 5
chr4_-_97784842 0.03 ENSRNOT00000007698
growth arrest and DNA-damage-inducible, alpha
chr8_+_69121682 0.03 ENSRNOT00000013461
ribosomal protein L4
chr10_+_90985653 0.03 ENSRNOT00000093364
coiled-coil domain containing 103
chr3_-_8659102 0.03 ENSRNOT00000050908
zinc finger, DHHC-type containing 12
chr10_-_20622600 0.03 ENSRNOT00000020554
fibrillarin-like 1
chrX_+_110818716 0.03 ENSRNOT00000086308
ring finger protein 128, E3 ubiquitin protein ligase
chr10_-_88144468 0.03 ENSRNOT00000084619
type I keratin KA11
chr9_+_100076958 0.03 ENSRNOT00000084297
dual specificity phosphatase 28
chr20_-_5469966 0.02 ENSRNOT00000092362
TAP binding protein
chr13_+_27032048 0.02 ENSRNOT00000031789
serpin family B member 13
chr6_+_146394456 0.02 ENSRNOT00000007683
similar to hypothetical protein
chr6_-_7421456 0.02 ENSRNOT00000006725
zinc finger protein 36, C3H type-like 2
chr6_+_27975849 0.02 ENSRNOT00000060810
dystrobrevin, beta
chr5_+_136014017 0.02 ENSRNOT00000025346
bestrophin 4
chr5_+_76150840 0.02 ENSRNOT00000020702
DnaJ heat shock protein family (Hsp40) member C25
chr12_-_19254527 0.02 ENSRNOT00000089349

chrX_-_135250519 0.02 ENSRNOT00000044487
E74 like ETS transcription factor 4
chr8_-_68312909 0.02 ENSRNOT00000066106
similar to ENSANGP00000021391
chr1_-_101514547 0.02 ENSRNOT00000079633
protein phosphatase 1, regulatory subunit 15A
chr1_+_22364551 0.02 ENSRNOT00000043157
trace amine-associated receptor 8a
chr1_-_141533908 0.02 ENSRNOT00000020117
mesoderm posterior bHLH transcription factor 1
chr3_-_5693147 0.02 ENSRNOT00000008660
family with sequence similarity 163, member B
chr10_+_53818818 0.02 ENSRNOT00000057260
myosin heavy chain 8
chr11_+_27208564 0.02 ENSRNOT00000002158
MAP3K7 C-terminal like
chr1_+_169562247 0.02 ENSRNOT00000023124
olfactory receptor 153
chr5_+_28395296 0.02 ENSRNOT00000009375
transmembrane protein 55A
chr18_-_26211445 0.02 ENSRNOT00000027739
neuronal regeneration related protein
chrX_+_131381134 0.02 ENSRNOT00000007474

chr3_+_91191837 0.02 ENSRNOT00000006097
recombination activating 2
chr3_+_37545238 0.02 ENSRNOT00000070792
TNF alpha induced protein 6
chr1_+_264507985 0.02 ENSRNOT00000085811
paired box 2
chr1_+_85003280 0.02 ENSRNOT00000057122
Fc fragment of IgG binding protein
chr19_+_10167797 0.02 ENSRNOT00000085440
cyclic nucleotide gated channel beta 1
chr10_-_109774639 0.02 ENSRNOT00000054955
Aly/REF export factor
chr16_-_47163898 0.02 ENSRNOT00000074490
coiled-coil domain containing 110
chr19_+_27404712 0.02 ENSRNOT00000023657
myosin light chain kinase 3
chr8_+_48718329 0.02 ENSRNOT00000089763
solute carrier family 37 member 4
chr9_+_81566074 0.02 ENSRNOT00000074131
ENSRNOT00000046229
ENSRNOT00000090383
paroxysmal nonkinesigenic dyskinesia
chr1_-_240601744 0.02 ENSRNOT00000024093
aldehyde dehydrogenase family 1, subfamily A7
chr20_+_295250 0.02 ENSRNOT00000000955
chloride intracellular channel 2
chr5_+_171297850 0.02 ENSRNOT00000034284
leucine rich repeat containing 47
chr1_+_102915191 0.02 ENSRNOT00000017851
lactate dehydrogenase C
chr4_+_6931495 0.02 ENSRNOT00000079770
WD repeat domain 86
chr4_-_113886994 0.02 ENSRNOT00000037333
HtrA serine peptidase 2
chr14_-_2371883 0.02 ENSRNOT00000000077
phosphodiesterase 6B
chr4_-_56656980 0.02 ENSRNOT00000009278
opsin 1 (cone pigments), short-wave-sensitive
chr12_+_22165486 0.01 ENSRNOT00000001890
motile sperm domain containing 3
chr4_+_7282948 0.01 ENSRNOT00000011052
cyclin-dependent kinase 5
chr19_-_37675077 0.01 ENSRNOT00000031033
enkurin domain containing 1
chr16_+_8823872 0.01 ENSRNOT00000027186
dorsal root ganglia homeobox
chr5_-_12172009 0.01 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr14_-_81426496 0.01 ENSRNOT00000018073
adducin 1
chr9_+_42620006 0.01 ENSRNOT00000019966
heparan sulfate 6-O-sulfotransferase 1
chr18_-_57031459 0.01 ENSRNOT00000026583
prenylcysteine oxidase 1 like
chr15_+_2766710 0.01 ENSRNOT00000017483
dual specificity phosphatase and pro isomerase domain containing 1
chr3_-_7498555 0.01 ENSRNOT00000017725
BarH-like homeobox 1
chr18_-_57515834 0.01 ENSRNOT00000026098
adrenoceptor beta 2
chr1_-_157494008 0.01 ENSRNOT00000013552
PCF11 cleavage and polyadenylation factor subunit
chr15_-_3544685 0.01 ENSRNOT00000015179
ENSRNOT00000085126
vinculin
chr3_-_133894569 0.01 ENSRNOT00000084221

chr4_-_40385349 0.01 ENSRNOT00000039005
G protein-coupled receptor 85
chr13_-_53137253 0.01 ENSRNOT00000011368
G protein-coupled receptor 25
chr15_-_27819376 0.01 ENSRNOT00000067400
RIKEN cDNA A930018M24 gene
chr3_+_120728688 0.01 ENSRNOT00000022596
BCL2 like 11
chr2_+_18392142 0.01 ENSRNOT00000043196
hyaluronan and proteoglycan link protein 1
chr13_+_52413241 0.01 ENSRNOT00000035157

chr20_+_37876650 0.01 ENSRNOT00000001054
gap junction protein, alpha 1
chr2_+_148722231 0.01 ENSRNOT00000018022
eukaryotic translation initiation factor 2A
chr2_-_138833933 0.01 ENSRNOT00000013343
protocadherin 18
chr9_-_19372673 0.01 ENSRNOT00000073667
ENSRNOT00000079517
chloride intracellular channel 5
chr10_-_98469799 0.01 ENSRNOT00000087502
ENSRNOT00000088646
ATP binding cassette subfamily A member 9
chr11_-_84037938 0.01 ENSRNOT00000002327
ATP binding cassette subfamily F member 3
chr5_-_117612123 0.01 ENSRNOT00000065112
dedicator of cytokinesis 7
chr6_-_114488880 0.01 ENSRNOT00000087560

chr1_+_164225934 0.01 ENSRNOT00000034389
microtubule-associated protein 6
chr17_+_11683862 0.01 ENSRNOT00000024766
msh homeobox 2
chr4_+_88584242 0.01 ENSRNOT00000008973
PIGY upstream reading frame
chr19_+_52077501 0.01 ENSRNOT00000079240
oxidative stress induced growth inhibitor 1
chr2_+_11658568 0.01 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr18_+_29386809 0.01 ENSRNOT00000082079
ENSRNOT00000024825
eukaryotic translation initiation factor 4E binding protein 3
chr3_-_110249627 0.01 ENSRNOT00000009866
signal recognition particle 14
chr5_+_156810991 0.01 ENSRNOT00000055904

chr1_-_8885967 0.01 ENSRNOT00000016102
gap junction protein, epsilon 1
chr10_+_65161152 0.01 ENSRNOT00000011608
crystallin, beta A1
chr5_-_147584038 0.01 ENSRNOT00000010983
zinc finger and BTB domain containing 8a
chr11_-_33003021 0.01 ENSRNOT00000084134
runt-related transcription factor 1
chr9_+_18564927 0.01 ENSRNOT00000061014
runt-related transcription factor 2
chr18_-_63488027 0.01 ENSRNOT00000023763
protein tyrosine phosphatase, non-receptor type 2
chr10_-_63240332 0.00 ENSRNOT00000005125
bleomycin hydrolase
chr3_-_10144388 0.00 ENSRNOT00000042495
ABL proto-oncogene 1, non-receptor tyrosine kinase
chr1_+_238222521 0.00 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr14_+_83560541 0.00 ENSRNOT00000057738
ENSRNOT00000085228
phosphoinositide-3-kinase interacting protein 1
chr6_+_132510757 0.00 ENSRNOT00000080230
Enah/Vasp-like
chr2_+_127845034 0.00 ENSRNOT00000044804
La ribonucleoprotein domain family, member 1B
chr20_-_3822754 0.00 ENSRNOT00000000541
ENSRNOT00000077357
solute carrier family 39 member 7
chr2_-_148722263 0.00 ENSRNOT00000017868
stress-associated endoplasmic reticulum protein 1
chr9_-_99659425 0.00 ENSRNOT00000051686
olfactory receptor 1343
chr11_-_87924816 0.00 ENSRNOT00000031819
serpin family D member 1
chr18_+_40596166 0.00 ENSRNOT00000087984
eukaryotic translation initiation factor 1A
chr1_-_101514974 0.00 ENSRNOT00000044788
protein phosphatase 1, regulatory subunit 15A
chr1_-_214844858 0.00 ENSRNOT00000046344
toll interacting protein
chr7_-_23948202 0.00 ENSRNOT00000044252
achaete-scute family bHLH transcription factor 4
chr7_+_28412198 0.00 ENSRNOT00000081822
ENSRNOT00000038780
ENSRNOT00000005995
insulin-like growth factor 1
chr1_+_256955652 0.00 ENSRNOT00000020411
leucine-rich, glioma inactivated 1
chr4_-_82141385 0.00 ENSRNOT00000008447
homeobox A3
chr5_-_171327450 0.00 ENSRNOT00000088710
coiled-coil domain containing 27
chr15_+_83707735 0.00 ENSRNOT00000057843
Kruppel-like factor 5
chr11_+_27101227 0.00 ENSRNOT00000002173
ubiquitin specific peptidase 16
chr3_-_110140756 0.00 ENSRNOT00000007882
G protein-coupled receptor 176

Network of associatons between targets according to the STRING database.

First level regulatory network of Maf_Nrl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.0 0.1 GO:0048619 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0061017 regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) hepatoblast differentiation(GO:0061017)
0.0 0.1 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)