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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Lhx3

Z-value: 0.34

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Transcription factors associated with Lhx3

Gene Symbol Gene ID Gene Info
ENSRNOG00000018427 LIM homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx3rn6_v1_chr3_-_3661810_36618100.951.2e-02Click!

Activity profile of Lhx3 motif

Sorted Z-values of Lhx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 0.30 ENSRNOT00000001313
Purkinje cell protein 2
chr1_-_264975132 0.12 ENSRNOT00000021748
ladybird homeobox 1
chr2_+_145174876 0.10 ENSRNOT00000040631
mab-21 like 1
chr15_-_93765498 0.09 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chrX_-_40086870 0.08 ENSRNOT00000010027
small muscle protein, X-linked
chr9_+_73418607 0.06 ENSRNOT00000092547
microtubule-associated protein 2
chr8_+_19888667 0.06 ENSRNOT00000078593
zinc finger protein 317
chr7_+_42304534 0.06 ENSRNOT00000085097
KIT ligand
chr10_+_103206014 0.05 ENSRNOT00000004081
tweety family member 2
chr8_-_7426611 0.05 ENSRNOT00000031492
Rho GTPase activating protein 42
chr13_-_83457888 0.05 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr12_+_25435567 0.05 ENSRNOT00000092982
general transcription factor II I
chr5_-_16799776 0.05 ENSRNOT00000011721
PLAG1 zinc finger
chr1_+_238222521 0.05 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr19_-_37528011 0.05 ENSRNOT00000059628
agouti related neuropeptide
chr9_+_66888393 0.05 ENSRNOT00000023536
calcium responsive transcription factor
chr8_-_119012671 0.04 ENSRNOT00000028435
parathyroid hormone 1 receptor
chr17_-_89923423 0.04 ENSRNOT00000076964
acyl-CoA binding domain containing 5
chr14_+_7026769 0.04 ENSRNOT00000071955
secretory calcium-binding phosphoprotein proline-glutamine rich 1-like
chr18_-_43945273 0.04 ENSRNOT00000088900
DTW domain containing 2
chr18_+_16146447 0.04 ENSRNOT00000022117
polypeptide N-acetylgalactosaminyltransferase 1
chr1_+_101603222 0.04 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr2_-_149444548 0.04 ENSRNOT00000018600
purinergic receptor P2Y12
chrX_+_151103576 0.04 ENSRNOT00000015401
SLIT and NTRK-like family, member 2
chr15_-_54528480 0.04 ENSRNOT00000066888
fibronectin type III domain containing 3a
chr3_-_71845232 0.04 ENSRNOT00000078645
calcitonin receptor like receptor
chr2_+_86996497 0.03 ENSRNOT00000042058
zinc finger protein 455
chr2_+_95320283 0.03 ENSRNOT00000015537
hes-related family bHLH transcription factor with YRPW motif 1
chr9_-_88086488 0.03 ENSRNOT00000019579
insulin receptor substrate 1
chr13_+_84474319 0.03 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
immunoglobulin-like domain containing receptor 2
chr14_+_36047144 0.03 ENSRNOT00000003088
ligand of numb-protein X 1
chrX_-_29648359 0.03 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr6_+_64789940 0.02 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr6_+_2216623 0.02 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr20_+_3155652 0.02 ENSRNOT00000042882
RT1 class Ib, locus S2
chr1_-_101095594 0.02 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr1_-_78180216 0.02 ENSRNOT00000071576
complement component 5a receptor 2
chr10_+_61685645 0.02 ENSRNOT00000003933
MAX network transcriptional repressor
chrX_-_111191932 0.02 ENSRNOT00000088050
ENSRNOT00000083613
MORC family CW-type zinc finger 4
chr3_+_148108539 0.02 ENSRNOT00000010149
RRAD and GEM like GTPase 1
chr9_-_42839837 0.02 ENSRNOT00000038610
neuralized E3 ubiquitin protein ligase 3
chr16_+_6048004 0.02 ENSRNOT00000020750
ARP8 actin-related protein 8 homolog
chr15_-_57651041 0.02 ENSRNOT00000072138
spermatid associated
chr12_-_39641285 0.02 ENSRNOT00000001729
anaphase promoting complex subunit 7
chr15_+_62406873 0.01 ENSRNOT00000047572
olfactomedin 4
chr2_-_31753528 0.01 ENSRNOT00000075057
phosphoinositide-3-kinase regulatory subunit 1
chr20_-_4542073 0.01 ENSRNOT00000000477
complement factor B
chr7_+_120923274 0.01 ENSRNOT00000049247
GTP binding protein 1
chr4_+_181315444 0.01 ENSRNOT00000044147
PPFIA binding protein 1
chr2_+_86996798 0.01 ENSRNOT00000070821
zinc finger protein 455
chr10_+_67810810 0.01 ENSRNOT00000079156
proteasome 26S subunit, non-ATPase 11
chr5_+_6373583 0.01 ENSRNOT00000084749

chr17_-_78812111 0.01 ENSRNOT00000021506
DNA cross-link repair 1C
chr19_-_29968424 0.01 ENSRNOT00000024981
inositol polyphosphate-4-phosphatase type II B
chr1_-_101819478 0.01 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr4_-_148437961 0.01 ENSRNOT00000082907
arachidonate 5-lipoxygenase
chr2_+_30685840 0.01 ENSRNOT00000031385
coiled-coil domain containing 125
chr9_+_73378057 0.01 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr7_-_105592804 0.01 ENSRNOT00000006789
adenylate cyclase 8
chr11_+_47061354 0.01 ENSRNOT00000039997
PEST proteolytic signal containing nuclear protein
chr8_+_117297670 0.01 ENSRNOT00000082628
glutaminyl-tRNA synthetase
chr14_+_39964588 0.01 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr10_+_67810655 0.01 ENSRNOT00000064285
proteasome 26S subunit, non-ATPase 11
chr18_+_59748444 0.01 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_+_23447366 0.01 ENSRNOT00000068629
pleckstrin and Sec7 domain containing 3
chr11_-_60547201 0.01 ENSRNOT00000093151
B and T lymphocyte associated
chr9_-_121725716 0.01 ENSRNOT00000087405
adenylate cyclase activating polypeptide 1
chr15_-_93307420 0.01 ENSRNOT00000012195
SLIT and NTRK-like family, member 1
chr3_+_102925471 0.00 ENSRNOT00000040364
olfactory receptor 772
chr18_+_55666027 0.00 ENSRNOT00000045950
similar to CDNA sequence BC023105
chr5_-_136166786 0.00 ENSRNOT00000026201
ring finger protein 220
chr6_+_18880737 0.00 ENSRNOT00000003432
alkB homolog 8, tRNA methyltransferase
chr7_-_140291620 0.00 ENSRNOT00000088323
adenylate cyclase 6
chr3_+_119561290 0.00 ENSRNOT00000015843
biliverdin reductase A
chr1_+_79631668 0.00 ENSRNOT00000083546
ENSRNOT00000035286
MHC I like leukocyte 1
chr9_+_38536920 0.00 ENSRNOT00000060452
primase (DNA) subunit 2
chrX_-_9999401 0.00 ENSRNOT00000060992
G protein-coupled receptor 82
chr17_+_53965562 0.00 ENSRNOT00000090387
geranylgeranyl diphosphate synthase 1
chr2_-_233743866 0.00 ENSRNOT00000087062
glutamyl aminopeptidase

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0070662 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.0 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)