Project
GSE49485: Hypoxia transcriptome sequencing of rat brain.
Navigation
Downloads
Results for Lef1
Z-value: 0.39
Motif logo
Transcription factors associated with Lef1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Lef1 | rn6_v1_chr2_+_236233239_236233239 | 0.55 | 3.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_28515025 Show fit | 0.17 |
ENSRNOT00000088033
ENSRNOT00000005317 ENSRNOT00000081141 |
DnaJ heat shock protein family (Hsp40) member C27 |
|
| chr3_+_147585947 Show fit | 0.16 |
ENSRNOT00000006833
|
scratch family transcriptional repressor 2 |
|
| chr16_-_74264142 Show fit | 0.16 |
ENSRNOT00000026067
|
dickkopf WNT signaling pathway inhibitor 4 |
|
| chr7_-_93826665 Show fit | 0.16 |
ENSRNOT00000011344
|
TNF receptor superfamily member 11B |
|
| chr2_+_150756185 Show fit | 0.14 |
ENSRNOT00000088461
ENSRNOT00000036808 |
muscleblind-like splicing regulator 1 |
|
| chr10_-_27179254 Show fit | 0.13 |
ENSRNOT00000004619
|
gamma-aminobutyric acid type A receptor gamma 2 subunit |
|
| chr2_-_142686577 Show fit | 0.13 |
ENSRNOT00000014562
|
NHL repeat containing 3 |
|
| chr3_+_47677720 Show fit | 0.12 |
ENSRNOT00000065340
|
T-box, brain, 1 |
|
| chr11_+_9642365 Show fit | 0.12 |
ENSRNOT00000087080
ENSRNOT00000042384 |
roundabout guidance receptor 1 |
|
| chr7_-_98098268 Show fit | 0.12 |
ENSRNOT00000010361
|
F-box protein 32 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Lef1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth(GO:0042489) |
| 0.0 | 0.2 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 0.0 | 0.2 | GO:0051799 | negative regulation of hair follicle development(GO:0051799) |
| 0.0 | 0.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.0 | 0.1 | GO:0021836 | chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.0 | 0.1 | GO:0072720 | response to dithiothreitol(GO:0072720) |
| 0.0 | 0.1 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.0 | 0.1 | GO:0099553 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 0.0 | 0.1 | GO:0060849 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.0 | 0.1 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.0 | 0.1 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.0 | GO:0043511 | inhibin complex(GO:0043511) |
| 0.0 | 0.0 | GO:0098855 | HCN channel complex(GO:0098855) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.1 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.0 | 0.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.0 | 0.1 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.0 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.0 | 0.0 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.0 | 0.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.0 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |