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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Klf12_Klf14_Sp4

Z-value: 0.71

Motif logo

Transcription factors associated with Klf12_Klf14_Sp4

Gene Symbol Gene ID Gene Info
ENSRNOG00000009145 Kruppel-like factor 12
ENSRNOG00000027557 Kruppel-like factor 14
ENSRNOG00000005472 Sp4 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf12rn6_v1_chr15_-_84748525_84748525-0.771.3e-01Click!
Klf14rn6_v1_chr4_-_58250798_582507980.741.5e-01Click!
Sp4rn6_v1_chr6_-_146195819_146195819-0.158.1e-01Click!

Activity profile of Klf12_Klf14_Sp4 motif

Sorted Z-values of Klf12_Klf14_Sp4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_78212350 1.50 ENSRNOT00000071098
InaF-motif containing 1
chr10_-_56962161 0.89 ENSRNOT00000026038
arachidonate 15-lipoxygenase
chr3_-_14395362 0.62 ENSRNOT00000092787
RAB14, member RAS oncogene family
chr20_-_29511382 0.57 ENSRNOT00000085026
DNA-damage-inducible transcript 4
chr14_-_82055290 0.56 ENSRNOT00000058062
RGD1560394
chr3_-_9037942 0.55 ENSRNOT00000036770
immediate early response 5-like
chr12_-_16934706 0.46 ENSRNOT00000001720
MAF bZIP transcription factor K
chr20_-_56197025 0.44 ENSRNOT00000073028
CD99 molecule
chrX_-_155862363 0.39 ENSRNOT00000089847
dyskerin pseudouridine synthase 1
chr20_+_12429315 0.37 ENSRNOT00000001675
poly(rC) binding protein 3
chr16_+_20352480 0.36 ENSRNOT00000025956
arrestin domain containing 2
chr12_+_12227010 0.35 ENSRNOT00000060843
ENSRNOT00000092610
BAI1-associated protein 2-like 1
chr1_+_80279706 0.33 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr20_+_5049496 0.32 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr2_-_25235275 0.32 ENSRNOT00000061580
F2R like trypsin receptor 1
chr7_+_120580743 0.31 ENSRNOT00000017181
MAF bZIP transcription factor F
chr12_-_30304036 0.30 ENSRNOT00000001218
nuclear protein 2, transcriptional regulator
chr4_-_123510217 0.29 ENSRNOT00000080734
solute carrier family 41, member 3
chr5_+_151413382 0.29 ENSRNOT00000012626
CD164 molecule like 2
chr5_-_153625869 0.28 ENSRNOT00000024464
chloride intracellular channel 4
chr9_-_9702306 0.27 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr16_-_20860767 0.26 ENSRNOT00000027275
ENSRNOT00000092417
growth differentiation factor 1
ceramide synthase 1
chr12_+_22641104 0.26 ENSRNOT00000001916
serpin family E member 1
chr8_+_64364741 0.26 ENSRNOT00000082840
CUGBP, Elav-like family member 6
chr20_+_6351458 0.26 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr3_-_14538241 0.26 ENSRNOT00000025904
stomatin
chr7_-_11648322 0.26 ENSRNOT00000026871
growth arrest and DNA-damage-inducible, beta
chr1_-_107373807 0.25 ENSRNOT00000056024
small VCP interacting protein
chr10_-_15166457 0.25 ENSRNOT00000026676
meteorin, glial cell differentiation regulator
chr15_+_40937708 0.23 ENSRNOT00000018407
spermatogenesis associated 13
chr2_+_122877286 0.23 ENSRNOT00000033080
arylsulfatase E
chr1_+_220826560 0.22 ENSRNOT00000027891
FOS like 1, AP-1 transcription factor subunit
chr1_-_47213749 0.22 ENSRNOT00000024656
dynein light chain Tctex-type 1
chr7_+_11414446 0.22 ENSRNOT00000027441
protein inhibitor of activated STAT, 4
chr10_+_55707164 0.22 ENSRNOT00000009757
hes family bHLH transcription factor 7
chr18_-_28454756 0.21 ENSRNOT00000040091
spermatogenesis associated 24
chr20_+_6102277 0.21 ENSRNOT00000033064
patatin-like phospholipase domain containing 1
chr14_-_83776863 0.21 ENSRNOT00000026481
smoothelin
chr12_-_24046814 0.21 ENSRNOT00000001961
cytochrome p450 oxidoreductase
chr7_-_18554227 0.21 ENSRNOT00000036172
ENSRNOT00000011047
heterogeneous nuclear ribonucleoprotein M
chr10_-_38782419 0.21 ENSRNOT00000073964
ubiquinol-cytochrome c reductase, complex III subunit VII
chr11_+_87204175 0.20 ENSRNOT00000000306
solute carrier family 25 member 1
chr1_+_163445527 0.20 ENSRNOT00000020520
leucine rich repeat containing 32
chr11_-_36479868 0.20 ENSRNOT00000075762
non-histone chromosomal protein HMG-14-like
chr7_+_12974169 0.20 ENSRNOT00000010555
C2 calcium-dependent domain containing 4C
chr16_-_8564379 0.19 ENSRNOT00000060975
hypothetical protein LOC680885
chr1_+_71416110 0.19 ENSRNOT00000084899
zinc finger protein 787
chr12_+_18531990 0.19 ENSRNOT00000036606
acetylserotonin O-methyltransferase-like
chr12_-_13668515 0.19 ENSRNOT00000086847
fascin actin-bundling protein 1
chr12_-_50383496 0.19 ENSRNOT00000000831
tyrosylprotein sulfotransferase 2
chr14_-_1461543 0.19 ENSRNOT00000075656
cytokine receptor-like factor 2
chr17_-_31411957 0.18 ENSRNOT00000060132
proteasome assembly chaperone 4
chr12_-_18530724 0.18 ENSRNOT00000078999
A-kinase anchoring protein 17A
chr16_-_8685529 0.18 ENSRNOT00000092751
solute carrier family 18 member A3
chr1_-_83990588 0.18 ENSRNOT00000002052
RAB4B, member RAS oncogene family
chr17_+_9653561 0.18 ENSRNOT00000018899
PDZ and LIM domain 7
chr19_-_9931930 0.18 ENSRNOT00000085144
coiled-coil domain containing 113
chr1_-_216663720 0.18 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr1_+_266075782 0.18 ENSRNOT00000026471
F-box and leucine-rich repeat protein 15
chr1_-_101175570 0.18 ENSRNOT00000073918
golgi-associated, olfactory signaling regulator
chr2_-_202816562 0.18 ENSRNOT00000020401
family with sequence similarity 46, member C
chr1_+_219345918 0.17 ENSRNOT00000025018
cyclin-dependent kinase 2 associated protein 2
chr20_-_2701815 0.17 ENSRNOT00000061950
heat shock protein family A (Hsp70) member 1A
chr16_-_20890949 0.17 ENSRNOT00000081977
homer scaffolding protein 3
chr14_+_83752393 0.17 ENSRNOT00000081123
selenoprotein M
chr10_-_91047177 0.17 ENSRNOT00000003986
complement C1q like 1
chr3_+_13838304 0.17 ENSRNOT00000025067
heat shock protein family A member 5
chr12_-_18540166 0.16 ENSRNOT00000001792
interleukin 3 receptor subunit alpha
chr3_+_171832500 0.16 ENSRNOT00000007554
VAMP associated protein B and C
chr1_-_80544825 0.16 ENSRNOT00000057802
ENSRNOT00000040060
ENSRNOT00000067049
ENSRNOT00000052387
ENSRNOT00000073352
RELB proto-oncogene, NF-kB subunit
chr8_-_22874637 0.16 ENSRNOT00000064551
ENSRNOT00000090424
dedicator of cytokinesis 6
chr12_+_22229079 0.15 ENSRNOT00000001911
G protein subunit beta 2
chr12_+_47218969 0.15 ENSRNOT00000081343
ENSRNOT00000038395
unc-119 lipid binding chaperone B
chr17_+_76002275 0.15 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr4_+_121612332 0.15 ENSRNOT00000077374
ENSRNOT00000084494
thioredoxin reductase 3
chr1_+_199655660 0.15 ENSRNOT00000027032
armadillo repeat containing 5
chr7_+_12619774 0.15 ENSRNOT00000015257
mediator complex subunit 16
chr3_+_11921715 0.15 ENSRNOT00000021689
family with sequence similarity 129, member B
chr1_+_81474553 0.15 ENSRNOT00000083493
pleckstrin homology-like domain, family B, member 3
chr12_-_4474729 0.15 ENSRNOT00000001418
ceramide synthase 4
chr17_+_31441630 0.15 ENSRNOT00000083705
ENSRNOT00000023582
tubulin, beta 2B class IIb
chr1_-_88686615 0.14 ENSRNOT00000070921
tubulin folding cofactor B
chr10_+_106812739 0.14 ENSRNOT00000074225
synaptogyrin 2
chr4_+_7662019 0.14 ENSRNOT00000014023
family with sequence similarity 126, member A
chr20_-_2701637 0.14 ENSRNOT00000049667
heat shock protein family A (Hsp70) member 1A
chr12_+_47551935 0.14 ENSRNOT00000056932
RGD1560398
chr5_-_173222440 0.14 ENSRNOT00000024897
von Willebrand factor A domain containing 1
chr13_+_52588917 0.14 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr18_+_24570762 0.13 ENSRNOT00000021738
RNA polymerase II subunit D
chr19_+_10731855 0.13 ENSRNOT00000022277
plasmolipin
chr1_-_101360971 0.13 ENSRNOT00000028164
lin-7 homolog B, crumbs cell polarity complex component
chr1_+_36320461 0.13 ENSRNOT00000023659
steroid 5 alpha-reductase 1
chr1_+_79831534 0.13 ENSRNOT00000057965
NOVA alternative splicing regulator 2
chr16_-_14348046 0.13 ENSRNOT00000018630
cadherin-related family member 1
chr20_-_4879779 0.13 ENSRNOT00000081924
heat shock protein family A (Hsp70) member 1B
chr16_+_19051965 0.13 ENSRNOT00000016399
solute carrier family 35, member E1
chr1_+_101178104 0.13 ENSRNOT00000028072
parathyroid hormone 2
chr10_+_49299125 0.13 ENSRNOT00000074853
trans-golgi network vesicle protein 23 homolog B
chrX_-_14890606 0.13 ENSRNOT00000049864
similar to RIKEN cDNA B630019K06
chr16_-_19894591 0.13 ENSRNOT00000085940
anoctamin 8
chr19_+_57047830 0.13 ENSRNOT00000080860
polypeptide N-acetylgalactosaminyltransferase 2
chr12_+_48481750 0.13 ENSRNOT00000000886
coronin 1C
chr1_+_261229347 0.13 ENSRNOT00000018485
ubiquitin domain containing 1
chr1_-_80580662 0.13 ENSRNOT00000024779
cleft lip and palate associated transmembrane protein 1
chr3_-_82368357 0.13 ENSRNOT00000000052
Cd82 molecule
chr12_-_38995570 0.13 ENSRNOT00000001806
ORAI calcium release-activated calcium modulator 1
chr8_+_22050222 0.12 ENSRNOT00000028096
intercellular adhesion molecule 5
chr10_+_55940533 0.12 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr3_+_171037957 0.12 ENSRNOT00000008764
RNA binding motif protein 38
chr1_+_101412736 0.12 ENSRNOT00000067468
luteinizing hormone beta polypeptide
chr2_-_195907450 0.12 ENSRNOT00000089402
tuftelin 1
chr4_+_171748273 0.12 ENSRNOT00000009998
deoxyribose-phosphate aldolase
chr2_-_195908037 0.12 ENSRNOT00000079776
tuftelin 1
chr20_+_5050327 0.12 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr16_-_7758189 0.12 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr7_+_11992543 0.12 ENSRNOT00000024576
abhydrolase domain containing 17A
chr5_-_136706936 0.12 ENSRNOT00000081925
ENSRNOT00000068130
coiled-coil domain containing 24
chr5_-_136002900 0.12 ENSRNOT00000025197
polo-like kinase 3
chr4_+_180961142 0.12 ENSRNOT00000002500
mediator complex subunit 21
chr5_+_157642751 0.12 ENSRNOT00000083577
ENSRNOT00000010308
capping actin protein of muscle Z-line beta subunit
chr19_-_25961666 0.12 ENSRNOT00000004091
calreticulin
chr16_+_83358116 0.12 ENSRNOT00000031109
RAB20, member RAS oncogene family
chr19_+_20607507 0.12 ENSRNOT00000000011
cerebellin 1 precursor
chr6_-_109004598 0.12 ENSRNOT00000007790
placental growth factor
chr9_-_10047507 0.12 ENSRNOT00000072118
alkB homolog 7
chr4_-_179477070 0.12 ENSRNOT00000030680
cancer susceptibility candidate 1
chr5_-_153790157 0.12 ENSRNOT00000025051
RCAN family member 3
chr17_+_78817529 0.12 ENSRNOT00000021918
meiosis/spermiogenesis associated 1
chr10_-_91117889 0.12 ENSRNOT00000031498
dephospho-CoA kinase domain containing
chr3_-_111080705 0.12 ENSRNOT00000079339
ras homolog family member V
chr10_-_56403188 0.12 ENSRNOT00000019947
cholinergic receptor nicotinic beta 1 subunit
chr1_-_91074294 0.12 ENSRNOT00000075236
similar to Cytochrome c oxidase polypeptide VIIa-heart, mitochondrial precursor (Cytochrome c oxidase subunit VIIa-H) (COX VIIa-M)
chr1_-_64099277 0.11 ENSRNOT00000084846
tRNA splicing endonuclease subunit 34
chr7_+_143629455 0.11 ENSRNOT00000073951
keratin 18
chr3_+_164424515 0.11 ENSRNOT00000083876
CCAAT/enhancer binding protein beta
chr10_+_7041510 0.11 ENSRNOT00000003514
calcium regulated heat stable protein 1
chr16_+_19767264 0.11 ENSRNOT00000051802
ENSRNOT00000092073
occludin/ELL domain containing 1
chr3_+_151553578 0.11 ENSRNOT00000045484
ERGIC and golgi 3
chr12_+_40619377 0.11 ENSRNOT00000001822
ENSRNOT00000081016
endoplasmic reticulum protein 29
chr8_+_96564877 0.11 ENSRNOT00000017879
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr1_-_190965115 0.11 ENSRNOT00000023483

chr18_+_79406381 0.11 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr8_+_119382011 0.11 ENSRNOT00000056060
LRR binding FLII interacting protein 2
chr3_+_15379109 0.11 ENSRNOT00000036495
MORN repeat containing 5
chr20_+_13156241 0.11 ENSRNOT00000050531
protein arginine methyltransferase 2
chr10_-_46593009 0.11 ENSRNOT00000047053
sterol regulatory element binding transcription factor 1
chr7_+_11215328 0.11 ENSRNOT00000061194
hypothetical protein LOC690617
chr8_+_53678777 0.11 ENSRNOT00000045944
dopamine receptor D2
chr1_+_274245184 0.10 ENSRNOT00000018889
dual specificity phosphatase 5
chr5_+_157282669 0.10 ENSRNOT00000022827
phospholipase A2 group IIA
chr19_+_26106838 0.10 ENSRNOT00000035987
hook microtubule-tethering protein 2
chr1_+_88182585 0.10 ENSRNOT00000044145
Yip1 interacting factor homolog B, membrane trafficking protein
chr3_+_150323116 0.10 ENSRNOT00000023429
ENSRNOT00000080485
RALY heterogeneous nuclear ribonucleoprotein
chr19_-_19509087 0.10 ENSRNOT00000019301
naked cuticle homolog 1
chr7_+_12314848 0.10 ENSRNOT00000028969
guanidinoacetate N-methyltransferase
chr10_-_102200596 0.10 ENSRNOT00000081519
family with sequence similarity 104, member A
chr5_+_159845774 0.10 ENSRNOT00000012328
Eph receptor A2
chr12_-_11265865 0.10 ENSRNOT00000001315
actin related protein 2/3 complex, subunit 1B
chr2_+_187737770 0.10 ENSRNOT00000036143
ENSRNOT00000092611
ENSRNOT00000092620
progestin and adipoQ receptor family member 6
chr1_-_221281180 0.10 ENSRNOT00000028379
CDC42 effector protein 2
chr1_+_91042635 0.10 ENSRNOT00000028211
tubulin-folding cofactor B
chr17_+_54280851 0.10 ENSRNOT00000024022
Rho GTPase activating protein 12
chr3_+_151032952 0.10 ENSRNOT00000064013
acyl-CoA synthetase short-chain family member 2
chr10_-_55642681 0.10 ENSRNOT00000057157

chr14_-_2297155 0.10 ENSRNOT00000000071
polycomb group ring finger 3
chr1_+_221448661 0.10 ENSRNOT00000072493
sororin-like
chr1_+_198690794 0.10 ENSRNOT00000023999
zinc finger protein 771
chr1_-_89329185 0.10 ENSRNOT00000078284
CD22 molecule
chr19_-_52499433 0.10 ENSRNOT00000021954
coactosin-like F-actin binding protein 1
chr16_-_75648538 0.09 ENSRNOT00000048414
defensin beta 14
chr4_-_113610243 0.09 ENSRNOT00000008813
hexokinase 2
chr2_+_251453644 0.09 ENSRNOT00000041897
zinc finger, HIT-type containing 6
chr16_-_19942343 0.09 ENSRNOT00000087162
ENSRNOT00000091906
bone marrow stromal cell antigen 2
chr10_-_45543897 0.09 ENSRNOT00000003926
guanylate kinase 1
chr12_+_22165486 0.09 ENSRNOT00000001890
motile sperm domain containing 3
chr2_+_190073815 0.09 ENSRNOT00000015473
S100 calcium binding protein A8
chrX_-_113584459 0.09 ENSRNOT00000025923
potassium voltage-gated channel subfamily E regulatory subunit 5
chr1_+_218632764 0.09 ENSRNOT00000019861
testis expressed metallothionein like protein
chr3_-_11410732 0.09 ENSRNOT00000034930
similar to Hypothetical UPF0184 protein C9orf16 homolog
chr7_+_11545024 0.09 ENSRNOT00000073221
solute carrier family 39 member 3
chr19_+_55094585 0.09 ENSRNOT00000068452
zinc finger protein, multitype 1
chr16_+_21288876 0.09 ENSRNOT00000027990
cartilage intermediate layer protein 2
chr6_-_6842758 0.09 ENSRNOT00000006094
potassium voltage-gated channel modifier subfamily G member 3
chr4_+_145580799 0.09 ENSRNOT00000013727
von Hippel-Lindau tumor suppressor
chr7_+_12471824 0.09 ENSRNOT00000068197
strawberry notch homolog 2
chr9_-_3965939 0.09 ENSRNOT00000088289

chr1_+_72732668 0.09 ENSRNOT00000024251
HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1
chr1_+_282134981 0.09 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr4_-_100883038 0.09 ENSRNOT00000041880
thymosin, beta 10-like
chr9_+_113699170 0.09 ENSRNOT00000017915
twisted gastrulation BMP signaling modulator 1
chr12_+_47074200 0.09 ENSRNOT00000014910
dynein light chain LC8-type 1
chr19_+_24747178 0.09 ENSRNOT00000038879
ENSRNOT00000079106
DnaJ heat shock protein family (Hsp40) member B1
chr12_+_47698947 0.09 ENSRNOT00000001586
transient receptor potential cation channel, subfamily V, member 4
chr7_-_70842405 0.08 ENSRNOT00000047449
neurexophilin 4
chr4_-_158010166 0.08 ENSRNOT00000026633
CD9 molecule
chr17_-_66397653 0.08 ENSRNOT00000024098
actinin alpha 2
chrX_+_29525256 0.08 ENSRNOT00000050018
RAB9A, member RAS oncogene family
chr12_-_13210758 0.08 ENSRNOT00000001438
KDEL endoplasmic reticulum protein retention receptor 2
chr1_-_88112683 0.08 ENSRNOT00000090615
sprouty-related, EVH1 domain containing 3
chr3_-_147809919 0.08 ENSRNOT00000085849
RANBP2-type and C3HC4-type zinc finger containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf12_Klf14_Sp4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0031439 positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
0.1 0.4 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.4 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.2 GO:0021539 subthalamus development(GO:0021539)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.6 GO:0045176 apical protein localization(GO:0045176)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.1 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.2 GO:0015746 citrate transport(GO:0015746)
0.0 0.1 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0 0.6 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.0 0.1 GO:0002397 MHC class I protein complex assembly(GO:0002397)
0.0 0.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.0 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:1904587 response to glycoprotein(GO:1904587)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.2 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0072566 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:1901491 notochord formation(GO:0014028) negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0098749 cerebellar neuron development(GO:0098749)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0052428 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0035934 corticosterone secretion(GO:0035934)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1901423 response to benzene(GO:1901423)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.6 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0071865 mammary gland bud morphogenesis(GO:0060648) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.0 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.1 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.0 0.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.0 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.0 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.0 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.0 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.0 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.0 GO:1904528 positive regulation of microtubule binding(GO:1904528)
0.0 0.2 GO:0034030 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.0 GO:0043096 purine nucleobase salvage(GO:0043096)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.1 GO:0006702 androgen biosynthetic process(GO:0006702) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.0 GO:0035976 AP1 complex(GO:0035976)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.0 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0031249 denatured protein binding(GO:0031249)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0046911 metal chelating activity(GO:0046911)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.0 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.0 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.0 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.0 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle