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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Isl2

Z-value: 0.72

Motif logo

Transcription factors associated with Isl2

Gene Symbol Gene ID Gene Info
ENSRNOG00000015336 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Isl2rn6_v1_chr8_+_60117729_601177290.444.5e-01Click!

Activity profile of Isl2 motif

Sorted Z-values of Isl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_91054974 0.23 ENSRNOT00000091089
C-reactive protein
chr7_+_144503534 0.23 ENSRNOT00000021543
tubulin folding cofactor A
chr13_-_83457888 0.22 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr7_+_2300434 0.21 ENSRNOT00000071785

chr8_+_130366775 0.20 ENSRNOT00000071152
natural killer cell triggering receptor
chr11_+_15081774 0.19 ENSRNOT00000009911
ubiquitin carboxyl-terminal hydrolase 25-like
chr1_-_252808380 0.18 ENSRNOT00000025856
cholesterol 25-hydroxylase
chr9_+_73378057 0.18 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr4_+_61814974 0.16 ENSRNOT00000074951
aldo-keto reductase family 1 member B10
chr2_+_86996497 0.16 ENSRNOT00000042058
zinc finger protein 455
chr1_+_192379543 0.16 ENSRNOT00000078705
protein kinase C, beta
chr3_+_63379031 0.16 ENSRNOT00000068199
oxysterol binding protein-like 6
chr4_-_155690869 0.15 ENSRNOT00000012216
complement C3a receptor 1
chr1_+_145770135 0.15 ENSRNOT00000015320
StAR-related lipid transfer domain containing 5
chr1_-_78180216 0.14 ENSRNOT00000071576
complement component 5a receptor 2
chr2_+_23289374 0.14 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr3_-_60765645 0.14 ENSRNOT00000050513
activating transcription factor 2
chr18_-_75207306 0.14 ENSRNOT00000021717
SET binding protein 1
chr18_+_1723565 0.14 ENSRNOT00000033468
growth regulation by estrogen in breast cancer 1 like
chr14_+_17228856 0.14 ENSRNOT00000003082
C-X-C motif chemokine ligand 9
chr15_+_87722221 0.14 ENSRNOT00000082688
sciellin
chr2_-_27343998 0.13 ENSRNOT00000091418
DNA polymerase kappa
chr16_+_84465656 0.13 ENSRNOT00000043188
LRRGT00175
chr18_+_74299931 0.13 ENSRNOT00000078403
ectopic P-granules autophagy protein 5 homolog
chr9_+_66889028 0.13 ENSRNOT00000087194
calcium responsive transcription factor
chr14_-_77810147 0.13 ENSRNOT00000035427
cytokine like 1
chr3_-_165700489 0.12 ENSRNOT00000017008
zinc finger protein 93
chr3_+_113918629 0.12 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr1_-_38538987 0.12 ENSRNOT00000090406
ENSRNOT00000071275
zinc finger protein 728-like
chr2_+_86996798 0.12 ENSRNOT00000070821
zinc finger protein 455
chr3_+_48626038 0.11 ENSRNOT00000009697
grancalcin
chr12_+_25435567 0.11 ENSRNOT00000092982
general transcription factor II I
chr12_-_35979193 0.11 ENSRNOT00000071104
transmembrane protein 132B
chr9_+_73418607 0.11 ENSRNOT00000092547
microtubule-associated protein 2
chr1_+_116604550 0.11 ENSRNOT00000083587
ubiquitin protein ligase E3A
chr3_-_138683318 0.11 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr9_+_61823531 0.11 ENSRNOT00000070844
methionyl-tRNA synthetase 2, mitochondrial
chr6_-_111477090 0.11 ENSRNOT00000016389
alkB homolog 1, histone H2A dioxygenase
chr7_+_24638208 0.10 ENSRNOT00000009135
mitochondrial transcription termination factor 2
chr1_+_253221812 0.10 ENSRNOT00000085880
ENSRNOT00000054753
kinesin family member 20B
chr1_+_101603222 0.10 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr1_-_43638161 0.10 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr3_+_48096954 0.10 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr10_-_36323055 0.10 ENSRNOT00000081026
zinc finger protein 354C
chr4_+_66090209 0.10 ENSRNOT00000031193
tetratricopeptide repeat domain 26
chr9_-_80166807 0.10 ENSRNOT00000079493
insulin-like growth factor binding protein 5
chr5_-_19559244 0.10 ENSRNOT00000014289
ENSRNOT00000089666
neutral sphingomyelinase activation associated factor
chr3_+_131351587 0.10 ENSRNOT00000010835
BTB domain containing 3
chr1_+_61786900 0.09 ENSRNOT00000090287

chr4_+_88694583 0.09 ENSRNOT00000009202
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr13_+_98311827 0.09 ENSRNOT00000082844
CDC42 binding protein kinase alpha
chrX_+_14019961 0.09 ENSRNOT00000004785
synaptotagmin-like 5
chr16_+_10417185 0.09 ENSRNOT00000082186
annexin A8
chr7_+_42304534 0.09 ENSRNOT00000085097
KIT ligand
chr15_-_55209342 0.09 ENSRNOT00000021752
RB transcriptional corepressor 1
chr7_-_139649286 0.09 ENSRNOT00000080056
SUMO1/sentrin specific peptidase 1
chr7_+_15422479 0.09 ENSRNOT00000066520
zinc finger protein 563
chr1_+_252409268 0.09 ENSRNOT00000026219
lipase, family member M
chr15_-_88670349 0.09 ENSRNOT00000012881
ring finger protein 219
chr6_-_42002819 0.09 ENSRNOT00000032417
growth regulation by estrogen in breast cancer 1
chr10_+_84966989 0.09 ENSRNOT00000013580
secernin 2
chr1_+_80028928 0.09 ENSRNOT00000012082
F-box protein 46
chr8_-_21519013 0.09 ENSRNOT00000042903
zinc finger protein 266
chr2_+_209661244 0.09 ENSRNOT00000091973

chr4_+_31229913 0.09 ENSRNOT00000077134
ENSRNOT00000087897
sterile alpha motif domain containing 9-like
chr6_-_108329464 0.08 ENSRNOT00000016040
ATP binding cassette subfamily D member 4
chr8_+_133197032 0.08 ENSRNOT00000075564
chemokine (C-C motif) receptor 5
chr13_+_34365147 0.08 ENSRNOT00000093066
cytoplasmic linker associated protein 1
chr17_+_45467015 0.08 ENSRNOT00000081408
glutathione peroxidase 5
chr17_+_53965562 0.08 ENSRNOT00000090387
geranylgeranyl diphosphate synthase 1
chr12_-_1195591 0.08 ENSRNOT00000001446
StAR-related lipid transfer domain containing 13
chr3_-_66885085 0.08 ENSRNOT00000084299
ENSRNOT00000090547
phosphodiesterase 1A
chr2_+_2729829 0.08 ENSRNOT00000017068
spermatogenesis associated 9
chr6_+_18880737 0.08 ENSRNOT00000003432
alkB homolog 8, tRNA methyltransferase
chr10_-_10881844 0.08 ENSRNOT00000087118
ENSRNOT00000004416
mahogunin ring finger 1
chr13_+_105684420 0.08 ENSRNOT00000040543
G patch domain containing 2
chr17_-_56068125 0.08 ENSRNOT00000022462
mitochondrial poly(A) polymerase
chr9_-_91100482 0.07 ENSRNOT00000064642
ubiquitin carboxyl-terminal hydrolase 40-like
chr2_+_248398917 0.07 ENSRNOT00000045855
guanylate binding protein 1
chr8_+_19888667 0.07 ENSRNOT00000078593
zinc finger protein 317
chr5_-_16799776 0.07 ENSRNOT00000011721
PLAG1 zinc finger
chr10_-_52290657 0.07 ENSRNOT00000005293
mitogen activated protein kinase kinase 4
chr17_-_87826421 0.07 ENSRNOT00000068156
Rho GTPase activating protein 21
chr2_-_157035483 0.07 ENSRNOT00000076491
similar to RalA binding protein 1
chr9_+_64434904 0.07 ENSRNOT00000075508
methionine--tRNA ligase, mitochondrial-like
chr16_-_25192675 0.07 ENSRNOT00000032289
membrane associated ring-CH-type finger 1
chr17_+_78764506 0.07 ENSRNOT00000077953
suppressor of variegation 3-9 homolog 2
chr1_-_87825333 0.07 ENSRNOT00000072689
zinc finger protein 74
chr8_-_102149912 0.07 ENSRNOT00000011263
similar to Ab2-095
chr8_-_21481735 0.07 ENSRNOT00000038069
zinc finger protein 426
chr3_+_8430829 0.07 ENSRNOT00000090440
ENSRNOT00000060969
cerebral endothelial cell adhesion molecule
chr14_+_79205466 0.07 ENSRNOT00000085534
TBC1 domain family, member 14
chr5_+_163867961 0.07 ENSRNOT00000081495

chr9_-_14550625 0.07 ENSRNOT00000078227
O-acyl-ADP-ribose deacylase 1
chr9_+_66888393 0.07 ENSRNOT00000023536
calcium responsive transcription factor
chr11_+_67101714 0.07 ENSRNOT00000078936
CD86 molecule
chr13_-_82295123 0.07 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr10_-_34242985 0.07 ENSRNOT00000046438
similar to novel protein
chr7_-_120770435 0.06 ENSRNOT00000077000
DEAD-box helicase 17
chr18_-_43945273 0.06 ENSRNOT00000088900
DTW domain containing 2
chr11_-_14160697 0.06 ENSRNOT00000081096
heat shock protein 70 family, member 13
chr18_-_26656879 0.06 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chr15_-_29548400 0.06 ENSRNOT00000078176

chr2_+_220432037 0.06 ENSRNOT00000021988
ferric-chelate reductase 1
chr4_-_176606382 0.06 ENSRNOT00000065576
RecQ like helicase
chr15_+_56666012 0.06 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr2_+_30664639 0.06 ENSRNOT00000076372
ENSRNOT00000076294
ENSRNOT00000076434
ENSRNOT00000076484
TATA-box binding protein associated factor 9
chr15_-_55424024 0.06 ENSRNOT00000077733
nudix hydrolase 15
chr1_-_53802658 0.06 ENSRNOT00000032667
afadin, adherens junction formation factor
chr6_+_8284878 0.06 ENSRNOT00000009581
solute carrier family 3 member 1
chr7_-_107768072 0.06 ENSRNOT00000093189
N-myc downstream regulated 1
chr17_+_84881414 0.06 ENSRNOT00000034157
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr12_-_38916237 0.06 ENSRNOT00000074517
transmembrane protein 120B
chr19_-_22194740 0.06 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr1_+_154446156 0.06 ENSRNOT00000093052
phosphatidylinositol binding clathrin assembly protein
chrX_+_33884499 0.06 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr4_-_51943519 0.05 ENSRNOT00000060459
protection of telomeres 1
chr18_+_30487264 0.05 ENSRNOT00000040125
protocadherin beta 10
chr6_-_108076186 0.05 ENSRNOT00000014814
family with sequence similarity 161, member B
chrX_-_128268285 0.05 ENSRNOT00000009755
ENSRNOT00000081880
THO complex 2
chr1_+_164706276 0.05 ENSRNOT00000024311
olfactory receptor 36
chrM_+_3904 0.05 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr5_+_36555109 0.05 ENSRNOT00000061128
F-box and leucine-rich repeat protein 4
chr6_-_3355339 0.05 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr7_-_124929025 0.05 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr2_-_30664163 0.05 ENSRNOT00000024801
RAD17 checkpoint clamp loader component
chr1_+_61382118 0.05 ENSRNOT00000050119
zinc finger protein 52
chr3_-_45169118 0.05 ENSRNOT00000086371
coiled-coil domain containing 148
chr14_-_45859908 0.05 ENSRNOT00000086994
phosphoglucomutase 2
chr1_-_64147251 0.05 ENSRNOT00000088502
CCR4-NOT transcription complex, subunit 3
chr19_-_49510901 0.05 ENSRNOT00000082929
ENSRNOT00000079969
hypothetical protein LOC687399
chr14_+_39663421 0.05 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr19_+_46455761 0.05 ENSRNOT00000034012
ENSRNOT00000093392
nudix hydrolase 7
chr4_+_176606649 0.05 ENSRNOT00000084700
golgi transport 1B
chr14_-_34561696 0.05 ENSRNOT00000059763
steroid 5 alpha-reductase 3
chr5_+_58995249 0.05 ENSRNOT00000023411
coiled-coil domain containing 107
chrX_+_77143892 0.05 ENSRNOT00000085227
ATPase copper transporting alpha
chr17_-_53713408 0.04 ENSRNOT00000022445
AT-rich interactive domain-containing protein 4B-like
chr7_+_125189827 0.04 ENSRNOT00000080152
ENSRNOT00000082805
parvin, beta
chr3_+_110442637 0.04 ENSRNOT00000010471
p21 (RAC1) activated kinase 6
chr15_+_39779648 0.04 ENSRNOT00000084505
calcium binding protein 39-like
chr10_+_59000397 0.04 ENSRNOT00000021134
MYB binding protein 1a
chr18_-_4294136 0.04 ENSRNOT00000091909
oxysterol binding protein-like 1A
chr8_+_64610952 0.04 ENSRNOT00000015963
myosin IXA
chr5_+_142986526 0.04 ENSRNOT00000012811
R-spondin 1
chr19_-_37796089 0.04 ENSRNOT00000024891
RAN binding protein 10
chrX_+_73390903 0.04 ENSRNOT00000077002
zinc finger protein 449
chrX_+_84064427 0.04 ENSRNOT00000046364
zinc finger protein 711
chr3_-_104018861 0.04 ENSRNOT00000008387
cholinergic receptor, muscarinic 5
chr3_+_8547349 0.04 ENSRNOT00000079108
ENSRNOT00000091697
spectrin, alpha, non-erythrocytic 1
chr5_+_120568242 0.04 ENSRNOT00000050597
leptin receptor
chr5_-_12172009 0.04 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_-_130338325 0.04 ENSRNOT00000071697
SEC22 homolog C, vesicle trafficking protein
chr3_+_151688454 0.04 ENSRNOT00000026856
reactive oxygen species modulator 1
chr3_+_107142762 0.04 ENSRNOT00000006177
similar to CDNA sequence BC052040
chr13_-_76049363 0.04 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr5_-_93244202 0.04 ENSRNOT00000075474
protein tyrosine phosphatase, receptor type, D
chr14_+_2892753 0.04 ENSRNOT00000061630
ecotropic viral integration site 5
chr1_+_30863217 0.04 ENSRNOT00000015421
ring finger protein 146
chr5_-_113532878 0.04 ENSRNOT00000010173
caspase activity and apoptosis inhibitor 1
chr17_-_76281660 0.04 ENSRNOT00000058070
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_-_148437961 0.04 ENSRNOT00000082907
arachidonate 5-lipoxygenase
chr3_+_93909156 0.04 ENSRNOT00000090365
LIM domain only 2
chr6_-_103935122 0.03 ENSRNOT00000058354
hypothetical protein LOC500684
chr5_+_144106802 0.03 ENSRNOT00000035637
ENSRNOT00000079779
LSM10, U7 small nuclear RNA associated
chr7_+_15247681 0.03 ENSRNOT00000006044
zinc finger protein 472
chr13_+_43818010 0.03 ENSRNOT00000005532
centrosomal protein of 170 kDa-like
chr4_-_66955732 0.03 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr4_-_150829913 0.03 ENSRNOT00000041571
calcium voltage-gated channel subunit alpha1 C
chr12_-_5685448 0.03 ENSRNOT00000077167
FRY microtubule binding protein
chr4_-_150829741 0.03 ENSRNOT00000051846
ENSRNOT00000052017
calcium voltage-gated channel subunit alpha1 C
chr9_+_11064605 0.03 ENSRNOT00000075121
signal transducing adaptor family member 2
chr12_+_41316764 0.03 ENSRNOT00000090867
2'-5'-oligoadenylate synthetase 3
chr1_-_67094567 0.03 ENSRNOT00000073583

chr1_+_201337416 0.03 ENSRNOT00000067742
BTB domain containing 16
chr10_-_86645529 0.03 ENSRNOT00000011947
mediator complex subunit 24
chr1_-_62114672 0.03 ENSRNOT00000072607

chr2_-_60461458 0.03 ENSRNOT00000024285
BRX1, biogenesis of ribosomes
chr13_-_94859390 0.03 ENSRNOT00000005467
ENSRNOT00000079763

chr20_+_8312792 0.03 ENSRNOT00000083108
cap methyltransferase 1
chr2_-_35870578 0.03 ENSRNOT00000066069
ring finger protein 180
chr1_-_167698263 0.03 ENSRNOT00000093046
tripartite motif-containing 21
chr1_-_126211439 0.03 ENSRNOT00000014988
tight junction protein 1
chr18_-_6782757 0.03 ENSRNOT00000068150
aquaporin 4
chr7_+_117456039 0.03 ENSRNOT00000051754
maestro heat-like repeat family member 1
chr13_+_78979321 0.03 ENSRNOT00000003857
ankyrin repeat domain 45
chrX_+_123751089 0.03 ENSRNOT00000092384
NFKB activating protein
chr8_-_40883880 0.03 ENSRNOT00000075593
disks large homolog 5-like
chr2_-_187786700 0.03 ENSRNOT00000092257
ENSRNOT00000092612
ENSRNOT00000068360
solute carrier family 25, member 44
chr6_+_76079880 0.03 ENSRNOT00000009304
similar to 1110008L16Rik protein
chr8_+_127702534 0.03 ENSRNOT00000075793
CTD small phosphatase like
chr5_-_113880911 0.03 ENSRNOT00000029441
equatorin
chr14_+_10786399 0.03 ENSRNOT00000003006
lin-54 DREAM MuvB core complex component
chr9_-_11027506 0.03 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr20_+_49319307 0.03 ENSRNOT00000057078
autophagy related 5
chr20_+_20259254 0.03 ENSRNOT00000085985
ENSRNOT00000077620
ENSRNOT00000090273
ankyrin 3
chr18_-_44141865 0.03 ENSRNOT00000083407
NACHT and WD repeat domain-containing protein 2-like
chr14_+_115396017 0.03 ENSRNOT00000067393
ankyrin repeat and SOCS box-containing 3
chr16_+_23447366 0.03 ENSRNOT00000068629
pleckstrin and Sec7 domain containing 3
chr1_-_227441442 0.03 ENSRNOT00000028433
membrane spanning 4-domains A1

Network of associatons between targets according to the STRING database.

First level regulatory network of Isl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:2000458 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0070662 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:1902962 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.0 GO:0046356 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0042262 dGTP catabolic process(GO:0006203) DNA protection(GO:0042262)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0032429 negative regulation of phospholipase activity(GO:0010519) regulation of phospholipase A2 activity(GO:0032429)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.0 GO:1904959 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0070401 NADP-retinol dehydrogenase activity(GO:0052650) NADP+ binding(GO:0070401)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0071791 chemokine (C-C motif) ligand 5 binding(GO:0071791)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0032551 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway