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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Isl2
Z-value: 0.72
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Transcription factors associated with Isl2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Isl2 | rn6_v1_chr8_+_60117729_60117729 | 0.44 | 4.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_+_91054974 Show fit | 0.23 |
ENSRNOT00000091089
|
C-reactive protein |
|
| chr7_+_144503534 Show fit | 0.23 |
ENSRNOT00000021543
|
tubulin folding cofactor A |
|
| chr13_-_83457888 Show fit | 0.22 |
ENSRNOT00000076289
ENSRNOT00000004065 |
SFT2 domain containing 2 |
|
| chr7_+_2300434 Show fit | 0.21 |
ENSRNOT00000071785
|
|
|
| chr8_+_130366775 Show fit | 0.20 |
ENSRNOT00000071152
|
natural killer cell triggering receptor |
|
| chr11_+_15081774 Show fit | 0.19 |
ENSRNOT00000009911
|
ubiquitin carboxyl-terminal hydrolase 25-like |
|
| chr1_-_252808380 Show fit | 0.18 |
ENSRNOT00000025856
|
cholesterol 25-hydroxylase |
|
| chr9_+_73378057 Show fit | 0.18 |
ENSRNOT00000043627
ENSRNOT00000045766 ENSRNOT00000092445 ENSRNOT00000037974 |
microtubule-associated protein 2 |
|
| chr4_+_61814974 Show fit | 0.16 |
ENSRNOT00000074951
|
aldo-keto reductase family 1 member B10 |
|
| chr2_+_86996497 Show fit | 0.16 |
ENSRNOT00000042058
|
zinc finger protein 455 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Isl2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0006431 | methionyl-tRNA aminoacylation(GO:0006431) |
| 0.1 | 0.2 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 0.1 | 0.2 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.0 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.2 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.0 | 0.2 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.0 | 0.1 | GO:0002462 | tolerance induction to nonself antigen(GO:0002462) |
| 0.0 | 0.1 | GO:0090024 | negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) |
| 0.0 | 0.1 | GO:0006579 | amino-acid betaine catabolic process(GO:0006579) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.1 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.0 | 0.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.0 | 0.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.1 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 0.1 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.0 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.3 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.1 | 0.2 | GO:0004825 | methionine-tRNA ligase activity(GO:0004825) |
| 0.1 | 0.2 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0070401 | NADP-retinol dehydrogenase activity(GO:0052650) NADP+ binding(GO:0070401) |
| 0.0 | 0.1 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.0 | 0.1 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 0.1 | GO:0071791 | chemokine (C-C motif) ligand 5 binding(GO:0071791) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |