ISMARA results: Irx5

Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Irx5

Z-value: 0.45

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Transcription factors associated with Irx5

Gene Symbol	Gene ID	Gene Info
Irx5 NCBI RGD Ensembl	ENSRNOG00000011180	iroquois homeobox 5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Irx5	rn6_v1_chr19_+_16415636_16415636	-0.52	3.7e-01	Click!

Activity profile of Irx5 motif

Sorted Z-values of Irx5 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_-_123638702 Show fit	0.32	ENSRNOT00000082473 ENSRNOT00000044470 ENSRNOT00000092017	Cyp2d1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_-_123630045 Show fit	0.22	ENSRNOT00000050002	Cyp2d1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily d, polypeptide 1
chr2_-_220838905 Show fit	0.19	ENSRNOT00000078914	AABR07013065.1 NCBI RGD Ensembl Show fit
chr5_-_166116516 Show fit	0.17	ENSRNOT00000079919 ENSRNOT00000080888	Kif1b NCBI RGD Ensembl Show fit	kinesin family member 1B
chr10_-_55997299 Show fit	0.16	ENSRNOT00000074505	Cyb5d1 NCBI RGD Ensembl Show fit	cytochrome b5 domain containing 1
chr2_+_251200686 Show fit	0.15	ENSRNOT00000019210	Col24a1 NCBI RGD Ensembl Show fit	collagen type XXIV alpha 1 chain
chr20_-_19479325 Show fit	0.14	ENSRNOT00000051491	Fam13c NCBI RGD Ensembl Show fit	family with sequence similarity 13, member C
chr9_-_45206427 Show fit	0.11	ENSRNOT00000042227	Aff3 NCBI RGD Ensembl Show fit	AF4/FMR2 family, member 3
chr12_-_29743705 Show fit	0.11	ENSRNOT00000001185	Caln1 NCBI RGD Ensembl Show fit	calneuron 1
chr17_-_86657473 Show fit	0.11	ENSRNOT00000078827	AABR07028795.1 NCBI RGD Ensembl Show fit

Showing 1 to 10 of 67 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.5	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.2	GO:0019520	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	GO:0032472	Golgi calcium ion transport(GO:0032472)

Showing 1 to 6 of 6 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.2	GO:0071821	FANCM-MHF complex(GO:0071821)
0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	GO:0097598	sperm cytoplasmic droplet(GO:0097598)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.5	GO:0070330	aromatase activity(GO:0070330)
0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)

Showing 1 to 5 of 5 entries

Results for Irx5

Z-value: 0.45

Motif logo

Transcription factors associated with Irx5

Activity-expression correlation:

Activity profile of Irx5 motif

Sorted Z-values of Irx5 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: