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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hsf4

Z-value: 0.61

Motif logo

Transcription factors associated with Hsf4

Gene Symbol Gene ID Gene Info
ENSRNOG00000015253 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf4rn6_v1_chr19_+_37229120_372291200.866.5e-02Click!

Activity profile of Hsf4 motif

Sorted Z-values of Hsf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_12952906 0.36 ENSRNOT00000078193
hypothetical protein LOC100360362
chr5_-_153924896 0.34 ENSRNOT00000065247
grainyhead-like transcription factor 3
chr1_+_83003841 0.31 ENSRNOT00000057384
carcinoembryonic antigen-related cell adhesion molecule 4
chr16_-_19942343 0.30 ENSRNOT00000087162
ENSRNOT00000091906
bone marrow stromal cell antigen 2
chr4_-_482645 0.30 ENSRNOT00000062073
ENSRNOT00000071713
canopy FGF signaling regulator 1
chr20_-_9855443 0.30 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chr12_-_23841049 0.29 ENSRNOT00000031555
heat shock protein family B (small) member 1
chr1_+_80135391 0.25 ENSRNOT00000021893
G protein-coupled receptor 4
chr2_-_187668677 0.24 ENSRNOT00000056898
ENSRNOT00000092563
TSSK6 activating co-chaperone
chr8_+_55178289 0.24 ENSRNOT00000059127
crystallin, alpha B
chr1_+_81643816 0.23 ENSRNOT00000027214
carcinoembryonic antigen-related cell adhesion molecule 1-like
chr4_-_161757447 0.23 ENSRNOT00000008737
FK506 binding protein 4
chr3_+_154043873 0.22 ENSRNOT00000072502
ENSRNOT00000034166
neuronatin
chr11_-_36479868 0.21 ENSRNOT00000075762
non-histone chromosomal protein HMG-14-like
chr1_+_90948976 0.20 ENSRNOT00000056877
succinate dehydrogenase assembly factor 1, mitochondrial
chr1_-_145931583 0.20 ENSRNOT00000016433
cilia and flagella associated protein 161
chr6_-_135112775 0.20 ENSRNOT00000086310
heat shock protein HSP 90-alpha
chr5_-_61410812 0.18 ENSRNOT00000015270
insulin-like growth factor binding protein-like 1
chr17_-_44834305 0.17 ENSRNOT00000084303
histone cluster 1, H2bd
chr1_+_279798187 0.17 ENSRNOT00000024065
pancreatic lipase
chr1_-_21854763 0.17 ENSRNOT00000089196
ENSRNOT00000020528
connective tissue growth factor
chr5_-_139864393 0.17 ENSRNOT00000030016
zinc finger protein 69
chr20_-_4921348 0.16 ENSRNOT00000082497
ENSRNOT00000041151
RT1 class I, locus CE4
chr9_+_10446699 0.16 ENSRNOT00000075344
hypothetical LOC301124
chr8_-_49301125 0.16 ENSRNOT00000091190
CD3e molecule
chr9_+_38456468 0.15 ENSRNOT00000016948
Bcl2-associated athanogene 2
chr8_+_48571323 0.15 ENSRNOT00000059776
coiled-coil domain containing 153
chr20_-_46305157 0.15 ENSRNOT00000000340
coiled-coil domain containing 162
chr10_-_105787803 0.15 ENSRNOT00000064671
jumonji domain containing 6
chr3_+_94035905 0.15 ENSRNOT00000014767
similar to RIKEN cDNA A930018P22
chr11_+_37798370 0.15 ENSRNOT00000002679
beta-site APP-cleaving enzyme 2
chr10_-_57436368 0.15 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr11_-_61530567 0.15 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_-_7051953 0.15 ENSRNOT00000013473
similar to hypothetical protein MGC29761
chr1_-_222293148 0.14 ENSRNOT00000028743
stress-induced phosphoprotein 1
chr13_+_96195836 0.14 ENSRNOT00000042547
similar to basic transcription factor 3
chr1_-_154170409 0.14 ENSRNOT00000089014
Hikeshi, heat shock protein nuclear import factor
chr1_+_81373340 0.14 ENSRNOT00000026814
zinc finger protein 428
chr20_+_295250 0.14 ENSRNOT00000000955
chloride intracellular channel 2
chr5_+_162351001 0.14 ENSRNOT00000065471
hypothetical protein LOC691162
chr14_+_22706901 0.13 ENSRNOT00000088798
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr5_+_169357517 0.13 ENSRNOT00000000079
acyl-CoA thioesterase 7
chr1_+_89162639 0.13 ENSRNOT00000028508
ATPase H+/K+ transporting alpha subunit
chr7_-_59763219 0.13 ENSRNOT00000041210
similar to 60S ribosomal protein L12
chrX_+_157095937 0.13 ENSRNOT00000091792
B-cell receptor-associated protein 31
chr6_+_99817431 0.12 ENSRNOT00000009621
churchill domain containing 1
chr1_-_164308317 0.12 ENSRNOT00000022983
serpin family H member 1
chr3_+_124088157 0.12 ENSRNOT00000028876
spermine oxidase
chr7_-_11754508 0.12 ENSRNOT00000026341
ornithine decarboxylase antizyme 1
chr20_-_29558321 0.12 ENSRNOT00000000702
anaphase promoting complex subunit 16
chr1_-_24190896 0.12 ENSRNOT00000016121
serum/glucocorticoid regulated kinase 1
chr5_+_116973159 0.12 ENSRNOT00000046475
uncharacterized LOC100912024
chr5_+_160095427 0.12 ENSRNOT00000077609

chr6_+_98284170 0.12 ENSRNOT00000031979
ras homolog family member J
chr8_-_87213627 0.11 ENSRNOT00000066084
cytochrome c oxidase subunit 7A2
chr7_-_125497691 0.11 ENSRNOT00000049445

chr5_-_127273656 0.11 ENSRNOT00000057341
DMRT-like family B with proline-rich C-terminal, 1
chr14_-_43143973 0.11 ENSRNOT00000003248
ubiquitin C-terminal hydrolase L1
chr15_+_32386816 0.11 ENSRNOT00000060322

chr8_+_99632803 0.11 ENSRNOT00000087190
phospholipid scramblase 1
chr2_-_84678790 0.11 ENSRNOT00000015886
chaperonin containing TCP1 subunit 5
chr1_-_190914610 0.11 ENSRNOT00000023189
cerebellar degeneration-related protein 2
chr10_-_13542077 0.10 ENSRNOT00000008736
ATPase H+ transporting V0 subunit C
chr11_+_30363280 0.10 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr10_+_105787935 0.10 ENSRNOT00000000266
methyltransferase like 23
chr11_+_39482408 0.10 ENSRNOT00000075126
high mobility group nucleosome binding domain 1
chr3_-_111087347 0.10 ENSRNOT00000018277
ras homolog family member V
chr6_-_127656603 0.10 ENSRNOT00000015516
serpin family A member 11
chrX_-_83864150 0.10 ENSRNOT00000073734
odorant binding protein I f
chr7_+_40318490 0.10 ENSRNOT00000081374
similar to hypothetical protein FLJ35821
chr3_+_111135021 0.10 ENSRNOT00000018970
delta like canonical Notch ligand 4
chr11_+_67221359 0.10 ENSRNOT00000086097
calcium-sensing receptor
chr5_-_155258392 0.10 ENSRNOT00000017065
complement C1q C chain
chr19_+_55381565 0.09 ENSRNOT00000018923
chromatin licensing and DNA replication factor 1
chr3_+_149706075 0.09 ENSRNOT00000034798
BPI fold containing family B, member 5
chrX_-_121731543 0.09 ENSRNOT00000018788
kelch-like family member 13
chr12_-_22021851 0.09 ENSRNOT00000039280
TSC22 domain family, member 4
chrX_+_111122552 0.09 ENSRNOT00000083566
ENSRNOT00000085078
ENSRNOT00000090928
claudin 2
chr1_+_82452469 0.09 ENSRNOT00000028026
exosome component 5
chr10_-_107539658 0.09 ENSRNOT00000089346
RNA binding protein, fox-1 homolog 3
chr1_+_193187972 0.09 ENSRNOT00000090172
ENSRNOT00000065342
solute carrier family 5 member 11
chr8_+_76426335 0.09 ENSRNOT00000085496
general transcription factor2A subunit 2
chr2_+_200397967 0.09 ENSRNOT00000025821
regenerating family member 4
chr1_-_220746224 0.09 ENSRNOT00000027734
barrier to autointegration factor 1
chr1_-_175676699 0.09 ENSRNOT00000030474
lymphatic vessel endothelial hyaluronan receptor 1
chr17_-_43776460 0.09 ENSRNOT00000089055
histone cluster 2, H3c2
chr9_+_81518176 0.09 ENSRNOT00000078317
ENSRNOT00000019265
ENSRNOT00000088246
ENSRNOT00000084682
actin related protein 2/3 complex, subunit 2
chr2_+_88344527 0.09 ENSRNOT00000059467
RGD1565641
chr2_+_60461551 0.09 ENSRNOT00000024557
RAD1 checkpoint DNA exonuclease
chr4_-_183426439 0.09 ENSRNOT00000083310
family with sequence similarity 60, member A
chr14_+_107767392 0.09 ENSRNOT00000012847
chaperonin containing TCP1 subunit 4
chr19_-_56677084 0.09 ENSRNOT00000024084
actin, alpha 1, skeletal muscle
chr16_-_48437223 0.09 ENSRNOT00000013005
ENSRNOT00000059401
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr4_+_170958196 0.09 ENSRNOT00000007905
phosphodiesterase 6H
chr1_-_30917882 0.09 ENSRNOT00000015440
ethylmalonyl-CoA decarboxylase 1
chr15_+_33632416 0.09 ENSRNOT00000068212

chr20_+_29558689 0.09 ENSRNOT00000085229
activating signal cointegrator 1 complex subunit 1
chr18_-_86279680 0.08 ENSRNOT00000006169
hypothetical protein LOC689166
chr14_+_88543630 0.08 ENSRNOT00000060515
heterogeneous nuclear ribonucleoprotein C
chr6_-_94980004 0.08 ENSRNOT00000006373
reticulon 1
chr7_+_72772440 0.08 ENSRNOT00000009989
metadherin
chr2_+_27713880 0.08 ENSRNOT00000083143
glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
chr10_-_57243435 0.08 ENSRNOT00000005050
cholinergic receptor nicotinic epsilon subunit
chr7_-_59882077 0.08 ENSRNOT00000068774
myelin regulatory factor-like
chr4_-_170932618 0.08 ENSRNOT00000007779
Rho GDP dissociation inhibitor beta
chr14_+_18983853 0.08 ENSRNOT00000003836
Ras association domain family member 6
chr20_-_5469966 0.08 ENSRNOT00000092362
TAP binding protein
chrX_-_45284341 0.08 ENSRNOT00000045436
odorant binding protein I f
chr8_+_45561390 0.08 ENSRNOT00000047820

chr5_-_58078545 0.08 ENSRNOT00000075777
ciliary neurotrophic factor receptor
chr20_-_5037022 0.08 ENSRNOT00000091022
ENSRNOT00000060762
mutS homolog 5
chr17_+_36771639 0.08 ENSRNOT00000015147
G protein-coupled receptor 50
chr8_+_54993859 0.08 ENSRNOT00000013093
interleukin 18
chr16_+_72216326 0.08 ENSRNOT00000051363
indoleamine 2,3-dioxygenase 1
chrX_+_15049462 0.08 ENSRNOT00000007015
emopamil binding protein (sterol isomerase)
chr10_+_3227160 0.07 ENSRNOT00000088075
N-terminal asparagine amidase
chr16_-_20807070 0.07 ENSRNOT00000072536
cartilage oligomeric matrix protein
chr14_-_64535170 0.07 ENSRNOT00000082338
glucosidase, beta, acid 3
chr1_-_100865894 0.07 ENSRNOT00000027580
prostate tumor overexpressed 1
chr7_+_143060597 0.07 ENSRNOT00000087481
keratin 7
chr20_-_30327361 0.07 ENSRNOT00000000689
solute carrier family 29 member 3
chr20_+_4087618 0.07 ENSRNOT00000000522
ENSRNOT00000060327
ENSRNOT00000080590
RT1 class II, locus Db1
chr8_+_69121682 0.07 ENSRNOT00000013461
ribosomal protein L4
chr5_-_125345726 0.07 ENSRNOT00000011244
similar to 60S ribosomal protein L32
chr1_-_48033343 0.07 ENSRNOT00000019531
ENSRNOT00000076422
t-complex 1
chr1_-_170397191 0.07 ENSRNOT00000090181
amyloid beta precursor protein binding family B member 1
chr4_-_113957774 0.07 ENSRNOT00000011921
INO80 complex subunit B
chr20_+_4966817 0.07 ENSRNOT00000081527
ENSRNOT00000081265
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr1_+_217039755 0.07 ENSRNOT00000091603
actin-like
chr6_-_55647665 0.07 ENSRNOT00000007414
basic leucine zipper and W2 domains 2
chr19_-_41161765 0.07 ENSRNOT00000023117
Hydin, axonemal central pair apparatus protein
chr5_+_129257429 0.07 ENSRNOT00000072396
tetratricopeptide repeat domain 39A
chr3_+_170994038 0.07 ENSRNOT00000081823
SPO11, initiator of meiotic double stranded breaks
chrX_+_128493614 0.07 ENSRNOT00000044240
stromal antigen 2
chr14_+_70164650 0.07 ENSRNOT00000004385
quinoid dihydropteridine reductase
chrX_-_73766885 0.07 ENSRNOT00000091325
ring finger protein, LIM domain interacting
chr11_-_81379640 0.07 ENSRNOT00000002484
eukaryotic translation initiation factor 4A2
chr15_+_87886783 0.07 ENSRNOT00000065710
SLAIN motif family, member 1
chr2_-_187258140 0.07 ENSRNOT00000017735
papillary renal cell carcinoma (translocation-associated)
chr11_-_38088753 0.06 ENSRNOT00000002713
transmembrane protease, serine 2
chr2_+_104290726 0.06 ENSRNOT00000017387
DnaJ heat shock protein family (Hsp40) member C5 beta
chr10_-_89199736 0.06 ENSRNOT00000027782
cytochrome C oxidase assembly factor 3
chrX_+_157150655 0.06 ENSRNOT00000090795
pregnancy up-regulated nonubiquitous CaM kinase
chr5_-_164747083 0.06 ENSRNOT00000010433
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr6_-_91518996 0.06 ENSRNOT00000005835
DNA polymerase epsilon 2, accessory subunit
chr1_+_165506361 0.06 ENSRNOT00000024156
uncoupling protein 2
chr12_+_4248808 0.06 ENSRNOT00000042410

chr1_-_88780425 0.06 ENSRNOT00000074494
succinate dehydrogenase complex assembly factor 1
chr16_+_6434468 0.06 ENSRNOT00000012906
calsequestrin-1-like
chr17_-_14627937 0.06 ENSRNOT00000020532
osteoglycin
chrX_-_74847379 0.06 ENSRNOT00000067009
ring finger protein, LIM domain interacting
chr20_-_32133431 0.06 ENSRNOT00000000443
serglycin
chr4_-_85174931 0.06 ENSRNOT00000014324
ENSRNOT00000088085
nucleotide-binding oligomerization domain containing 1
chrX_+_13441558 0.06 ENSRNOT00000030170
similar to Ferritin light chain (Ferritin L subunit)
chr10_-_77512032 0.06 ENSRNOT00000003295
phosphatidylcholine transfer protein
chr20_+_21316826 0.06 ENSRNOT00000000785
similar to RIKEN cDNA 1700040L02
chr1_-_102780381 0.06 ENSRNOT00000080132
serum amyloid A4
chr9_-_85626094 0.06 ENSRNOT00000020919
serpin family E member 2
chr7_-_141185710 0.06 ENSRNOT00000085033
Fas apoptotic inhibitory molecule 2
chr8_-_109576353 0.06 ENSRNOT00000010320
protein phosphatase 2, regulatory subunit B'', alpha
chr7_-_107203897 0.06 ENSRNOT00000086263
leucine rich repeat containing 6
chr19_-_37952501 0.06 ENSRNOT00000026809
dipeptidase 3
chr2_-_53413638 0.06 ENSRNOT00000021081
growth hormone receptor
chr7_-_123586919 0.06 ENSRNOT00000011484
NADH:ubiquinone oxidoreductase subunit A6
chr10_+_43601689 0.06 ENSRNOT00000029238
mitochondrial ribosomal protein L22
chr9_+_116652530 0.06 ENSRNOT00000029210
l(3)mbt-like 4 (Drosophila)
chr13_+_76962504 0.06 ENSRNOT00000076581
ring finger and WD repeat domain 2
chr4_+_52147641 0.06 ENSRNOT00000009458
hyaluronoglucosaminidase 4
chr1_-_227175096 0.05 ENSRNOT00000054811

chr19_+_24747178 0.05 ENSRNOT00000038879
ENSRNOT00000079106
DnaJ heat shock protein family (Hsp40) member B1
chr8_-_111965889 0.05 ENSRNOT00000032376
beaded filament structural protein 2
chr8_+_128790348 0.05 ENSRNOT00000025142
solute carrier family 25, member 38
chrX_-_1346181 0.05 ENSRNOT00000042736
60S ribosomal protein L12-like
chrX_-_112159458 0.05 ENSRNOT00000087403
testis expressed 13B
chr7_+_11737293 0.05 ENSRNOT00000046059
leucine rich repeat and Ig domain containing 3
chr17_-_27969433 0.05 ENSRNOT00000073967
neuritin 1
chr3_+_2877293 0.05 ENSRNOT00000061855
lipocalin 5
chr19_-_26006970 0.05 ENSRNOT00000004570
glutaryl-CoA dehydrogenase
chr12_-_31323810 0.05 ENSRNOT00000001247
RAN, member RAS oncogene family
chr1_+_214317682 0.05 ENSRNOT00000032904
transmembrane protein 80
chr14_+_3058993 0.05 ENSRNOT00000002807
growth factor independent 1 transcriptional repressor
chr6_-_128690741 0.05 ENSRNOT00000035826
spectrin repeat containing, nuclear envelope family member 3
chr5_-_151768123 0.05 ENSRNOT00000079380
nuclear distribution C, dynein complex regulator
chr1_-_252461461 0.05 ENSRNOT00000026093
ankyrin repeat domain 22
chr19_-_26082719 0.05 ENSRNOT00000083159
ribonuclease H2, subunit A
chr9_+_95161157 0.05 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr12_+_22153983 0.05 ENSRNOT00000080775
ENSRNOT00000001894
procollagen C-endopeptidase enhancer
chr6_+_55648021 0.05 ENSRNOT00000064822
ENSRNOT00000091488
ankyrin repeat and MYND domain containing 2
chr3_+_11396070 0.05 ENSRNOT00000037399
CDKN1A interacting zinc finger protein 1
chr7_-_30105132 0.05 ENSRNOT00000091227
nuclear receptor subfamily 1, group H, member 4
chr1_+_90729274 0.05 ENSRNOT00000047207
similar to NADH:ubiquinone oxidoreductase B15 subunit
chr12_+_17252093 0.05 ENSRNOT00000047634
zinc finger AN1-type containing 2A
chr2_+_25041185 0.05 ENSRNOT00000040983
zinc finger, BED-type containing 3
chr1_-_102741581 0.05 ENSRNOT00000016254
similar to Serum amyloid A-3 protein precursor
chr1_-_86923575 0.05 ENSRNOT00000027029
mitochondrial ribosomal protein S12
chr5_+_57028467 0.05 ENSRNOT00000010061
DnaJ heat shock protein family (Hsp40) member A1
chr2_+_198312428 0.05 ENSRNOT00000028758
splicing factor 3b, subunit 4
chr3_+_122928964 0.05 ENSRNOT00000074724
rCG26795-like
chr20_+_26999795 0.05 ENSRNOT00000057872
myopalladin
chr1_+_214317965 0.05 ENSRNOT00000078754
transmembrane protein 80

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901252 negative regulation of dendritic cell cytokine production(GO:0002731) regulation of intracellular transport of viral material(GO:1901252)
0.1 0.3 GO:1903544 cellular response to interleukin-11(GO:0071348) response to butyrate(GO:1903544)
0.1 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.3 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.0 0.4 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163) regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0002666 positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0002397 MHC class I protein complex assembly(GO:0002397)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0090131 skeletal muscle thin filament assembly(GO:0030240) mesenchyme migration(GO:0090131)
0.0 0.1 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.0 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.0 GO:1904252 histone H3-R17 methylation(GO:0034971) negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:2000371 phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:0034475 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365) negative regulation of mRNA modification(GO:0090367)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.0 GO:1990091 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) sodium-dependent self proteolysis(GO:1990091)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0002501 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0017042 glycosylceramidase activity(GO:0017042)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0001565 phorbol ester receptor activity(GO:0001565)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse