ISMARA results: Hsf2

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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hsf2

Z-value: 0.68

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Transcription factors associated with Hsf2

Gene Symbol	Gene ID	Gene Info
Hsf2 NCBI RGD Ensembl	ENSRNOG00000000808	heat shock transcription factor 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Hsf2	rn6_v1_chr20_+_38935820_38935820	-0.09	8.9e-01	Click!

Activity profile of Hsf2 motif

Sorted Z-values of Hsf2 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr20_-_9855443 Show fit	0.32	ENSRNOT00000090275 ENSRNOT00000066266	Tff3 NCBI RGD Ensembl Show fit	trefoil factor 3
chr15_-_108898703 Show fit	0.27	ENSRNOT00000067577	Zic5 NCBI RGD Ensembl Show fit	Zic family member 5
chr19_+_41482728 Show fit	0.25	ENSRNOT00000022943	Calb2 NCBI RGD Ensembl Show fit	calbindin 2
chr4_-_482645 Show fit	0.23	ENSRNOT00000062073 ENSRNOT00000071713	Cnpy1 NCBI RGD Ensembl Show fit	canopy FGF signaling regulator 1
chr14_-_6679878 Show fit	0.22	ENSRNOT00000075989 ENSRNOT00000067875	Spp1 NCBI RGD Ensembl Show fit	secreted phosphoprotein 1
chr1_-_145870912 Show fit	0.20	ENSRNOT00000016289	Il16 NCBI RGD Ensembl Show fit	interleukin 16
chr10_+_103395511 Show fit	0.19	ENSRNOT00000004256	Gprc5c NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member C
chr1_+_145770135 Show fit	0.15	ENSRNOT00000015320	Stard5 NCBI RGD Ensembl Show fit	StAR-related lipid transfer domain containing 5
chr7_+_144647587 Show fit	0.15	ENSRNOT00000022398	Hoxc4 NCBI RGD Ensembl Show fit	homeo box C4
chr6_+_64808238 Show fit	0.14	ENSRNOT00000093195	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0006710	androgen catabolic process(GO:0006710)
0.0	0.2	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.2	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.1	GO:1990790	response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.0	0.1	GO:0035759	mesangial cell-matrix adhesion(GO:0035759)
0.0	0.1	GO:0009609	response to symbiotic bacterium(GO:0009609)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0002572	pro-T cell differentiation(GO:0002572)

Showing 1 to 10 of 35 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.0	0.1	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0	0.1	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)

Showing 1 to 8 of 8 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.3	GO:0071837	HMG box domain binding(GO:0071837)
0.2	GO:0032052	bile acid binding(GO:0032052)
0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	GO:0015489	ornithine decarboxylase inhibitor activity(GO:0008073) polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1	GO:0048030	disaccharide binding(GO:0048030)

Showing 1 to 10 of 20 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events

Showing 1 to 1 of 1 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation

Showing 1 to 2 of 2 entries

Results for Hsf2

Z-value: 0.68

Motif logo

Transcription factors associated with Hsf2

Activity-expression correlation:

Activity profile of Hsf2 motif

Sorted Z-values of Hsf2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: