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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxd8

Z-value: 0.26

Motif logo

Transcription factors associated with Hoxd8

Gene Symbol Gene ID Gene Info
ENSRNOG00000042480 homeobox D8

Activity profile of Hoxd8 motif

Sorted Z-values of Hoxd8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_73418607 0.12 ENSRNOT00000092547
microtubule-associated protein 2
chrX_-_40086870 0.11 ENSRNOT00000010027
small muscle protein, X-linked
chr2_+_145174876 0.11 ENSRNOT00000040631
mab-21 like 1
chr10_+_61685645 0.09 ENSRNOT00000003933
MAX network transcriptional repressor
chr5_-_12199283 0.08 ENSRNOT00000007769
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr2_-_96509424 0.08 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr16_+_31734944 0.07 ENSRNOT00000059673
palladin, cytoskeletal associated protein
chr10_+_103206014 0.06 ENSRNOT00000004081
tweety family member 2
chr15_+_24078280 0.06 ENSRNOT00000015511
ENSRNOT00000063807
mitogen-activated protein kinase 1 interacting protein 1-like
chr5_-_166116516 0.06 ENSRNOT00000079919
ENSRNOT00000080888
kinesin family member 1B
chr1_-_90149991 0.06 ENSRNOT00000076987
similar to RIKEN cDNA 4931406P16
chr16_+_84465656 0.06 ENSRNOT00000043188
LRRGT00175
chr9_+_71915421 0.06 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr2_-_33025271 0.06 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr10_+_764421 0.05 ENSRNOT00000084608
ENSRNOT00000087567
myosin heavy chain 11
chr3_+_63379031 0.05 ENSRNOT00000068199
oxysterol binding protein-like 6
chr12_+_25435567 0.05 ENSRNOT00000092982
general transcription factor II I
chr1_-_164977633 0.05 ENSRNOT00000029629
ring finger protein 169
chr6_-_98666007 0.05 ENSRNOT00000082695

chr11_+_65743892 0.05 ENSRNOT00000085226

chr13_+_105684420 0.05 ENSRNOT00000040543
G patch domain containing 2
chr15_+_39638510 0.05 ENSRNOT00000037800
RCC1 and BTB domain containing protein 1
chr7_+_42304534 0.05 ENSRNOT00000085097
KIT ligand
chr10_-_87286387 0.05 ENSRNOT00000044206
keratin 28
chr1_-_128287151 0.05 ENSRNOT00000084946
ENSRNOT00000089723
myocyte enhancer factor 2a
chr4_-_66955732 0.05 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr18_-_43945273 0.05 ENSRNOT00000088900
DTW domain containing 2
chr2_-_200003443 0.05 ENSRNOT00000024900
ENSRNOT00000088041
phosphodiesterase 4D interacting protein
chr4_-_151428894 0.05 ENSRNOT00000010556
adiponectin receptor 2
chr14_-_82171480 0.04 ENSRNOT00000021952
nuclear receptor binding SET domain protein 2
chr2_-_231521052 0.04 ENSRNOT00000089534
ENSRNOT00000080470
ENSRNOT00000084756
ankyrin 2
chr17_-_89923423 0.04 ENSRNOT00000076964
acyl-CoA binding domain containing 5
chr5_+_116420690 0.04 ENSRNOT00000087089
nuclear factor I/A
chr2_+_127525285 0.04 ENSRNOT00000093247
inturned planar cell polarity protein
chr19_-_22194740 0.04 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr2_-_113345577 0.04 ENSRNOT00000034096
fibronectin type III domain containing 3B
chr1_+_248132090 0.04 ENSRNOT00000022056
interleukin 33
chr3_+_48106099 0.04 ENSRNOT00000007218
solute carrier family 4 member 10
chr13_-_100450209 0.04 ENSRNOT00000090712
lamin B receptor
chr15_-_93765498 0.04 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chr13_-_94859390 0.04 ENSRNOT00000005467
ENSRNOT00000079763

chr17_+_54298409 0.04 ENSRNOT00000084919
Rho GTPase activating protein 12
chr13_+_43818010 0.04 ENSRNOT00000005532
centrosomal protein of 170 kDa-like
chr9_+_52687868 0.04 ENSRNOT00000083864
WD repeat domain 75
chr13_-_83457888 0.03 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr7_-_73883812 0.03 ENSRNOT00000065722
serine/threonine kinase 3
chr11_-_37253776 0.03 ENSRNOT00000002215
DS cell adhesion molecule
chr17_-_79085076 0.03 ENSRNOT00000057851
family with sequence similarity 171, member A1
chr18_+_63599425 0.03 ENSRNOT00000023145
centrosomal protein 192
chr9_+_73378057 0.03 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr11_-_83300409 0.03 ENSRNOT00000029255
VPS8 CORVET complex subunit
chr7_-_15073052 0.03 ENSRNOT00000037708
zinc finger protein 799
chr16_-_9658484 0.03 ENSRNOT00000065216
mitogen-activated protein kinase 8
chrX_+_123770337 0.02 ENSRNOT00000092554
NFKB activating protein
chr7_-_70319346 0.02 ENSRNOT00000071543
Ts translation elongation factor, mitochondrial
chr8_+_133210473 0.02 ENSRNOT00000082774
chemokine (C-C motif) receptor 5
chr3_+_161121697 0.02 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr5_-_100977902 0.02 ENSRNOT00000077429
zinc finger, DHHC-type containing 21
chr10_+_70136855 0.02 ENSRNOT00000084076
DNA ligase 3
chr12_+_47590154 0.02 ENSRNOT00000045946
GIT ArfGAP 2
chr19_-_37796089 0.02 ENSRNOT00000024891
RAN binding protein 10
chr18_+_47456327 0.02 ENSRNOT00000020030
serum response factor binding protein 1
chr12_-_2245324 0.02 ENSRNOT00000001332
ENSRNOT00000001333
Fc fragment of IgE receptor II
chr3_+_113918629 0.02 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr7_+_70987861 0.02 ENSRNOT00000072906
nuclear envelope integral membrane protein 1
chr8_-_21453190 0.02 ENSRNOT00000078192
zinc finger protein 26
chr19_-_29968424 0.02 ENSRNOT00000024981
inositol polyphosphate-4-phosphatase type II B
chr2_-_166682325 0.02 ENSRNOT00000091198
ENSRNOT00000012422
serine palmitoyltransferase, small subunit B
chr9_+_10941613 0.02 ENSRNOT00000070794
semaphorin 6B
chr10_+_67810655 0.02 ENSRNOT00000064285
proteasome 26S subunit, non-ATPase 11
chr13_+_27465930 0.02 ENSRNOT00000003314
serpin family B member 10
chr5_+_147185474 0.02 ENSRNOT00000000134
adenylate kinase 2
chr17_+_36691875 0.02 ENSRNOT00000074314
similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a)
chrX_-_82743753 0.01 ENSRNOT00000003512
ribosomal protein S6 kinase A6
chr18_-_85980833 0.01 ENSRNOT00000058179
suppressor of cytokine signaling 6
chr1_+_15642153 0.01 ENSRNOT00000079845
microtubule-associated protein 7
chr1_+_273854248 0.01 ENSRNOT00000044827
ENSRNOT00000017600
ENSRNOT00000086496
adducin 3
chr3_-_37854561 0.01 ENSRNOT00000076095
nebulin
chr10_+_67810810 0.01 ENSRNOT00000079156
proteasome 26S subunit, non-ATPase 11
chr6_-_38007162 0.01 ENSRNOT00000044583

chr3_-_104018861 0.01 ENSRNOT00000008387
cholinergic receptor, muscarinic 5
chr4_+_68635581 0.01 ENSRNOT00000016217
single stranded DNA binding protein 1
chr5_-_56567320 0.01 ENSRNOT00000066081
TOP1 binding arginine/serine rich protein
chr1_+_107262659 0.01 ENSRNOT00000022499
growth arrest-specific 2
chr13_+_96303703 0.01 ENSRNOT00000084718
ENSRNOT00000029723
EF-hand calcium binding domain 2
chr16_+_70081035 0.01 ENSRNOT00000016098
ubiquitin carboxyl-terminal hydrolase 12-like
chr2_+_220432037 0.01 ENSRNOT00000021988
ferric-chelate reductase 1
chr9_-_11108741 0.01 ENSRNOT00000072357
coiled-coil domain containing 94
chr4_+_65112944 0.01 ENSRNOT00000083672
aldo-keto reductase family 1, member D1
chr8_-_126390801 0.01 ENSRNOT00000089732

chr12_+_38377034 0.01 ENSRNOT00000088002
CAP-GLY domain containing linker protein 1
chr12_-_46493203 0.01 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chr1_+_88955440 0.01 ENSRNOT00000091101
proline dehydrogenase 2
chr17_-_27279260 0.01 ENSRNOT00000018508
small nuclear ribonucleoprotein U11/U12 subunit 48
chr8_-_118436894 0.01 ENSRNOT00000073395
ATR-interacting protein-like
chr12_-_10967326 0.01 ENSRNOT00000042095
ubiquitin carboxyl-terminal hydrolase 12-like
chr14_+_6221085 0.01 ENSRNOT00000068215

chrX_+_144994139 0.01 ENSRNOT00000071783
pre-mRNA-splicing factor CWC22 homolog
chr11_-_60547201 0.01 ENSRNOT00000093151
B and T lymphocyte associated
chr6_+_18880737 0.01 ENSRNOT00000003432
alkB homolog 8, tRNA methyltransferase
chr1_+_213511874 0.01 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_30685840 0.00 ENSRNOT00000031385
coiled-coil domain containing 125
chr3_-_45169118 0.00 ENSRNOT00000086371
coiled-coil domain containing 148
chr3_-_22459257 0.00 ENSRNOT00000091747
DENN domain containing 1A
chr2_+_86996497 0.00 ENSRNOT00000042058
zinc finger protein 455
chr14_+_81858737 0.00 ENSRNOT00000029784
ENSRNOT00000058068
ENSRNOT00000058067
DNA polymerase nu
chr8_+_1459526 0.00 ENSRNOT00000034503
kelch repeat and BTB domain containing 3
chr5_+_103251986 0.00 ENSRNOT00000008757
centlein
chr18_+_17043903 0.00 ENSRNOT00000068139
formin homology 2 domain containing 3
chrX_-_76925195 0.00 ENSRNOT00000087977
ATRX, chromatin remodeler
chr13_-_90405591 0.00 ENSRNOT00000006849
VANGL planar cell polarity protein 2
chrX_+_54390733 0.00 ENSRNOT00000004977
similar to chromosome X open reading frame 21
chr13_-_67206688 0.00 ENSRNOT00000003630
ENSRNOT00000090693
phospholipase A2 group IVA
chr19_+_6046665 0.00 ENSRNOT00000084126
cadherin 8
chr8_+_100260049 0.00 ENSRNOT00000011090

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.0 GO:0070666 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.0 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)