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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hoxd1
Z-value: 0.52
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Transcription factors associated with Hoxd1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hoxd1 | rn6_v1_chr3_+_61685619_61685619 | -0.54 | 3.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_84465656 Show fit | 0.30 |
ENSRNOT00000043188
|
LRRGT00175 |
|
| chr6_-_3355339 Show fit | 0.27 |
ENSRNOT00000084602
|
mitogen-activated protein kinase kinase kinase kinase 3 |
|
| chr5_-_168734296 Show fit | 0.23 |
ENSRNOT00000066120
|
calmodulin binding transcription activator 1 |
|
| chr12_-_35979193 Show fit | 0.23 |
ENSRNOT00000071104
|
transmembrane protein 132B |
|
| chr1_+_141767940 Show fit | 0.22 |
ENSRNOT00000064034
|
zinc finger protein 710 |
|
| chr9_+_73378057 Show fit | 0.20 |
ENSRNOT00000043627
ENSRNOT00000045766 ENSRNOT00000092445 ENSRNOT00000037974 |
microtubule-associated protein 2 |
|
| chr3_+_56125924 Show fit | 0.19 |
ENSRNOT00000011380
|
ubiquitin protein ligase E3 component n-recognin 3 |
|
| chr14_+_42015347 Show fit | 0.19 |
ENSRNOT00000044017
|
ATPase phospholipid transporting 8A1 |
|
| chr16_-_10802512 Show fit | 0.18 |
ENSRNOT00000079554
|
bone morphogenetic protein receptor type 1A |
|
| chr12_-_45801842 Show fit | 0.18 |
ENSRNOT00000078837
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of Hoxd1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.2 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 0.2 | GO:0048378 | lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382) regulation of cardiac ventricle development(GO:1904412) |
| 0.1 | 0.2 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.0 | 0.2 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.0 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.2 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.0 | 0.2 | GO:0001302 | replicative cell aging(GO:0001302) |
| 0.0 | 0.2 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.2 | GO:0042048 | olfactory behavior(GO:0042048) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.2 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.0 | 0.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.1 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.1 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.0 | 0.0 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.2 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.0 | 0.2 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 0.1 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 0.0 | 0.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |