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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxc6

Z-value: 0.28

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Transcription factors associated with Hoxc6

Gene Symbol Gene ID Gene Info
ENSRNOG00000016442 homeo box C6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc6rn6_v1_chr7_+_144623555_1446235550.316.1e-01Click!

Activity profile of Hoxc6 motif

Sorted Z-values of Hoxc6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_59883839 0.33 ENSRNOT00000093579
aspartoacylase
chr17_+_78793336 0.30 ENSRNOT00000057898
metallothionein 1
chrX_+_136460215 0.22 ENSRNOT00000093538
Rho GTPase activating protein 36
chr9_+_25410669 0.16 ENSRNOT00000030912
ENSRNOT00000090920
transcription factor AP-2 beta
chr4_-_82173207 0.10 ENSRNOT00000074167
homeo box A5
chr2_-_96032722 0.08 ENSRNOT00000015746
proteasome subunit beta type 6-like
chr1_+_101541266 0.06 ENSRNOT00000028436
hydroxysteroid (17-beta) dehydrogenase 14
chr12_-_47919400 0.06 ENSRNOT00000073774
mevalonate kinase
chr7_+_79638046 0.05 ENSRNOT00000029419
zinc finger protein, multitype 2
chr7_+_38742051 0.05 ENSRNOT00000006070
decorin
chr12_+_40895515 0.05 ENSRNOT00000046323
protein tyrosine phosphatase, non-receptor type 11
chr5_+_147257678 0.04 ENSRNOT00000066268
ring finger protein 19B
chr7_+_34402738 0.03 ENSRNOT00000030985
coiled-coil domain containing 38
chr3_+_56766475 0.03 ENSRNOT00000078819
Sp5 transcription factor
chr13_+_89385859 0.03 ENSRNOT00000047434
Fc fragment of IgG receptor IIIa
chr7_-_145062956 0.03 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr14_+_9555264 0.03 ENSRNOT00000002928
NK6 homeobox 1
chr17_+_6667564 0.03 ENSRNOT00000025916
heterogeneous nuclear ribonucleoprotein K
chr14_+_91557601 0.03 ENSRNOT00000038733
hypothetical LOC289778
chr10_-_44147035 0.02 ENSRNOT00000041113
olfactory receptor 1424
chr11_-_70211701 0.02 ENSRNOT00000076114
mucin 13, cell surface associated
chr3_-_46601409 0.02 ENSRNOT00000079261
phospholipase A2 receptor 1
chr1_+_224933529 0.02 ENSRNOT00000088282
WD repeat domain 74
chr1_+_128606770 0.02 ENSRNOT00000073355
tetratricopeptide repeat domain 23
chr8_-_87245951 0.02 ENSRNOT00000015299
transmembrane protein 30A
chr8_+_116307141 0.02 ENSRNOT00000037375
Ras association domain family member 1
chr13_+_89386023 0.02 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr16_-_7412150 0.02 ENSRNOT00000047252
similar to ribosomal protein S24
chr1_+_167944448 0.02 ENSRNOT00000087667
olfactory receptor 56
chr6_+_50954631 0.02 ENSRNOT00000078953
component of oligomeric golgi complex 5
chr3_-_113342675 0.01 ENSRNOT00000020130
stereocilin
chr2_+_52431601 0.01 ENSRNOT00000023554
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr13_-_113872097 0.01 ENSRNOT00000010799
ENSRNOT00000084320
complement C3b/C4b receptor 1 like
chrX_-_83151511 0.01 ENSRNOT00000057378
highly divergent homeobox
chr9_-_30251388 0.01 ENSRNOT00000035033
succinate dehydrogenase complex assembly factor 4
chr19_-_62150423 0.01 ENSRNOT00000073524
ENSRNOT00000091209
coiled-coil domain containing 7
chr5_-_79008363 0.01 ENSRNOT00000010040
kinesin family member 12
chr2_-_23909016 0.01 ENSRNOT00000084044
secretory carrier membrane protein 1
chr9_-_4685383 0.01 ENSRNOT00000061896
sulfotransferase family 1C member 2
chr14_-_85484275 0.01 ENSRNOT00000083770
kringle containing transmembrane protein 1
chr4_-_176381477 0.00 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chr2_-_205426869 0.00 ENSRNOT00000023333
synaptonemal complex protein 1
chr2_-_61414038 0.00 ENSRNOT00000051910
ENSRNOT00000088202
threonyl-tRNA synthetase
chr14_+_37116492 0.00 ENSRNOT00000002921
sarcoglycan, beta
chr2_-_140334912 0.00 ENSRNOT00000015067
E74-like factor 2
chr5_+_10178302 0.00 ENSRNOT00000009679
syntrophin, gamma 1
chr1_+_227240383 0.00 ENSRNOT00000074127
membrane spanning 4-domains A6E
chr7_-_55604403 0.00 ENSRNOT00000088732
ataxin 7-like 3B
chr20_-_31402483 0.00 ENSRNOT00000033529
H2A histone family, member Y2
chr10_+_38661901 0.00 ENSRNOT00000009098
zinc finger CCHC-type containing 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046687 response to chromate(GO:0046687)
0.0 0.1 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.0 0.2 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0019767 IgE receptor activity(GO:0019767)