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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxc4_Arx_Otp_Esx1_Phox2b

Z-value: 0.92

Motif logo

Transcription factors associated with Hoxc4_Arx_Otp_Esx1_Phox2b

Gene Symbol Gene ID Gene Info
ENSRNOG00000016613 homeo box C4
ENSRNOG00000053562 aristaless related homeobox
ENSRNOG00000010560 orthopedia homeobox
ENSRNOG00000048011 ESX homeobox 1
ENSRNOG00000051929 paired-like homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arxrn6_v1_chrX_+_62363953_623639530.951.2e-02Click!
Otprn6_v1_chr2_+_24546536_245465360.385.2e-01Click!
Hoxc4rn6_v1_chr7_+_144647587_1446475870.237.1e-01Click!
Phox2brn6_v1_chr14_+_42714315_427143150.108.7e-01Click!

Activity profile of Hoxc4_Arx_Otp_Esx1_Phox2b motif

Sorted Z-values of Hoxc4_Arx_Otp_Esx1_Phox2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_2174131 2.26 ENSRNOT00000001313
Purkinje cell protein 2
chr1_-_190370499 1.35 ENSRNOT00000084389

chr10_-_88670430 1.12 ENSRNOT00000025547
hypocretin neuropeptide precursor
chrX_+_144994139 0.83 ENSRNOT00000071783
pre-mRNA-splicing factor CWC22 homolog
chr2_+_127525285 0.83 ENSRNOT00000093247
inturned planar cell polarity protein
chr15_+_37790141 0.72 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr4_+_169161585 0.61 ENSRNOT00000079785
epithelial membrane protein 1
chrX_-_40086870 0.59 ENSRNOT00000010027
small muscle protein, X-linked
chr2_+_158097843 0.56 ENSRNOT00000016541
pentraxin 3
chr10_+_61685645 0.48 ENSRNOT00000003933
MAX network transcriptional repressor
chr2_+_122877286 0.44 ENSRNOT00000033080
arylsulfatase E
chr2_+_145174876 0.40 ENSRNOT00000040631
mab-21 like 1
chr3_+_159368273 0.39 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr4_+_169147243 0.35 ENSRNOT00000011580
epithelial membrane protein 1
chr18_-_55891710 0.29 ENSRNOT00000064686
synaptopodin
chr10_+_43601689 0.29 ENSRNOT00000029238
mitochondrial ribosomal protein L22
chrX_-_138118696 0.27 ENSRNOT00000084130
FERM domain containing 7
chr15_-_34198921 0.27 ENSRNOT00000024991
neural retina leucine zipper
chr14_+_34446616 0.26 ENSRNOT00000002976
clock circadian regulator
chr19_-_43192208 0.24 ENSRNOT00000025179
exosome component 6
chr4_+_29535852 0.23 ENSRNOT00000087619
collagen, type I, alpha 2
chr16_+_7035241 0.22 ENSRNOT00000084977
NIMA-related kinase 4
chr6_+_28382962 0.22 ENSRNOT00000016976
proopiomelanocortin
chr6_-_104290579 0.21 ENSRNOT00000066014
enhancer of rudimentary homolog (Drosophila)
chr5_-_2982603 0.21 ENSRNOT00000045460
potassium voltage-gated channel subfamily B member 2
chr6_+_104291071 0.20 ENSRNOT00000006798
solute carrier family 39, member 9
chr4_-_18396035 0.20 ENSRNOT00000034692
semaphorin 3A
chr14_-_115052450 0.20 ENSRNOT00000067998
acylphosphatase 2
chr10_+_103206014 0.20 ENSRNOT00000004081
tweety family member 2
chr17_-_79085076 0.19 ENSRNOT00000057851
family with sequence similarity 171, member A1
chr2_-_198706428 0.19 ENSRNOT00000085006
RNA polymerase III subunit G like
chr4_+_168752133 0.19 ENSRNOT00000010289
apolipoprotein L domain containing 1
chr1_-_278042312 0.17 ENSRNOT00000018693
actin-binding LIM protein 1
chr3_+_163552166 0.17 ENSRNOT00000049082
TP53 regulating kinase
chr5_+_187312 0.17 ENSRNOT00000030857
zinc finger protein 120-like
chr7_+_28654733 0.16 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr3_+_3389612 0.15 ENSRNOT00000041984
ribosomal protein L8
chr14_-_16903242 0.15 ENSRNOT00000003001
shroom family member 3
chr16_+_70081035 0.14 ENSRNOT00000016098
ubiquitin carboxyl-terminal hydrolase 12-like
chr9_+_71915421 0.13 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr8_+_71914867 0.13 ENSRNOT00000023372
death-associated protein kinase 2
chr12_+_49665282 0.13 ENSRNOT00000086397
G protein-coupled receptor kinase 3
chr1_+_80279706 0.13 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr13_-_102857551 0.13 ENSRNOT00000080309
microtubule affinity regulating kinase 1
chr20_+_3176107 0.12 ENSRNOT00000001036
RT1 class Ib, locus S3
chr4_-_180505916 0.12 ENSRNOT00000086465

chr6_+_101532518 0.12 ENSRNOT00000075054
gephyrin
chr10_-_67401836 0.12 ENSRNOT00000073071
cytokine receptor-like factor 3
chr17_-_14627937 0.12 ENSRNOT00000020532
osteoglycin
chr20_+_3155652 0.12 ENSRNOT00000042882
RT1 class Ib, locus S2
chr20_+_42966140 0.12 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr2_+_30685840 0.12 ENSRNOT00000031385
coiled-coil domain containing 125
chr8_-_83280888 0.11 ENSRNOT00000052341
GDNF family receptor alpha like
chrX_+_111735820 0.11 ENSRNOT00000086948
FERM and PDZ domain containing 3
chr12_-_10967326 0.11 ENSRNOT00000042095
ubiquitin carboxyl-terminal hydrolase 12-like
chr16_-_20562399 0.11 ENSRNOT00000031692
leucine rich repeat containing 25
chr5_-_161981441 0.10 ENSRNOT00000020316
podoplanin
chr7_-_143967484 0.10 ENSRNOT00000081758
Sp7 transcription factor
chr13_-_50514151 0.10 ENSRNOT00000003951
renin
chr2_+_240642847 0.10 ENSRNOT00000079694
ubiquitin-conjugating enzyme E2D 3
chr3_-_57607683 0.10 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr14_+_45982244 0.10 ENSRNOT00000076881
ENSRNOT00000002984
RELT-like 1
chr15_-_80713153 0.10 ENSRNOT00000063800
kelch-like family member 1
chr18_-_43945273 0.10 ENSRNOT00000088900
DTW domain containing 2
chr4_+_88328061 0.10 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr20_+_3246739 0.09 ENSRNOT00000061299
RT1 class I, locus T24, gene 2
chr17_-_87826421 0.09 ENSRNOT00000068156
Rho GTPase activating protein 21
chr4_-_168656673 0.09 ENSRNOT00000009341
G protein-coupled receptor 19
chr12_+_25435567 0.09 ENSRNOT00000092982
general transcription factor II I
chr5_+_28485619 0.08 ENSRNOT00000093341
ENSRNOT00000093129
uncharacterized LOC100912373
chr20_+_44680449 0.08 ENSRNOT00000000728
Traf3 interacting protein 2
chr11_-_62067655 0.08 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr8_-_126390801 0.08 ENSRNOT00000089732

chr1_-_215284548 0.08 ENSRNOT00000090375
cortactin
chr5_+_50381244 0.08 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr6_+_104291340 0.08 ENSRNOT00000089313
solute carrier family 39, member 9
chr13_-_111581018 0.08 ENSRNOT00000083072
ENSRNOT00000077981
SERTA domain containing 4
chr6_-_7058314 0.08 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr4_+_180291389 0.08 ENSRNOT00000002465
sarcospan
chr17_-_22678253 0.08 ENSRNOT00000083122
LRRGT00112-like
chr4_+_24612205 0.08 ENSRNOT00000057382
EWS RNA-binding protein 1
chr10_-_29026002 0.08 ENSRNOT00000005070
pituitary tumor-transforming 1
chrX_+_74200972 0.07 ENSRNOT00000076956
cysteine-rich hydrophobic domain 1
chrX_-_77559348 0.07 ENSRNOT00000047823
fibronectin type III domain containing 3C1
chr20_+_4966817 0.07 ENSRNOT00000081527
ENSRNOT00000081265
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_83084975 0.07 ENSRNOT00000017947
Rho guanine nucleotide exchange factor 7
chr3_-_111087347 0.07 ENSRNOT00000018277
ras homolog family member V
chr12_-_35979193 0.07 ENSRNOT00000071104
transmembrane protein 132B
chr6_+_47940183 0.07 ENSRNOT00000011951
acireductone dioxygenase 1
chr19_+_39229754 0.07 ENSRNOT00000050612
vacuolar protein sorting 4 homolog A
chr10_-_4257868 0.07 ENSRNOT00000035886
TNF receptor superfamily member 17
chr13_-_32427177 0.07 ENSRNOT00000044628
cadherin 19
chr17_-_90071408 0.06 ENSRNOT00000071978
decaprenyl diphosphate synthase subunit 1
chr1_+_88113445 0.06 ENSRNOT00000056955
gametogenetin
chr3_-_120076788 0.06 ENSRNOT00000047158
potassium voltage-gated channel interacting protein 3
chr7_-_28711761 0.06 ENSRNOT00000006249
PARP1 binding protein
chr6_-_26241337 0.06 ENSRNOT00000006525
solute carrier family 4 member 1 adaptor protein
chr9_+_10941613 0.06 ENSRNOT00000070794
semaphorin 6B
chr12_-_46493203 0.06 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chr13_+_57243877 0.06 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr7_+_2458833 0.06 ENSRNOT00000085092
nascent polypeptide-associated complex alpha subunit
chr2_+_80269661 0.06 ENSRNOT00000015975

chr9_+_61692154 0.06 ENSRNOT00000082300
heat shock protein family E member 1
chr10_+_29033989 0.06 ENSRNOT00000088322
SLU7 homolog, splicing factor
chr19_+_40855433 0.06 ENSRNOT00000023823
interleukin 34
chr2_-_185852759 0.06 ENSRNOT00000049461
mab-21 like 2
chr1_-_215033460 0.06 ENSRNOT00000044565
dual specificity phosphatase 8
chr17_+_22984844 0.06 ENSRNOT00000078310
neural precursor cell expressed, developmentally down-regulated 9
chr9_+_27546528 0.06 ENSRNOT00000051403
KH homology domain containing 1
chrX_+_15113878 0.06 ENSRNOT00000007464
WD repeat domain 13
chr17_-_43776460 0.05 ENSRNOT00000089055
histone cluster 2, H3c2
chr9_-_105693357 0.05 ENSRNOT00000066968
nudix hydrolase 12
chr4_-_72143748 0.05 ENSRNOT00000024428
TRPM8 channel-associated factor 1
chr8_+_40009691 0.05 ENSRNOT00000042679
V-set and immunoglobulin domain containing 2
chr5_-_119564846 0.05 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr11_+_36851038 0.05 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr4_+_155321553 0.05 ENSRNOT00000089614
microfibrillar associated protein 5
chr20_+_3230052 0.05 ENSRNOT00000078454
RT1 class I, locus T24, gene 3
chr3_+_14889510 0.05 ENSRNOT00000080760
DAB2 interacting protein
chr9_+_20241062 0.05 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr8_+_106449321 0.05 ENSRNOT00000018622
retinol binding protein 1
chr1_-_107373807 0.05 ENSRNOT00000056024
small VCP interacting protein
chr4_-_157304653 0.05 ENSRNOT00000051613
leucine rich repeat containing 23
chr11_+_46184871 0.05 ENSRNOT00000048417
Trk-fused gene
chr4_-_115208026 0.05 ENSRNOT00000084388
ENSRNOT00000066678
deoxyguanosine kinase
chr14_+_82769642 0.05 ENSRNOT00000065393
C-terminal binding protein 1
chr3_-_154627257 0.05 ENSRNOT00000018328
transglutaminase 2
chr16_+_2537248 0.05 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr17_-_89923423 0.05 ENSRNOT00000076964
acyl-CoA binding domain containing 5
chr3_-_37854561 0.05 ENSRNOT00000076095
nebulin
chr1_+_229416489 0.05 ENSRNOT00000028617
olfactory receptor 336
chr8_-_39460844 0.04 ENSRNOT00000048875
PBX/knotted 1 homeobox 2
chr18_-_37819097 0.04 ENSRNOT00000025880
dihydropyrimidinase-like 3
chr2_+_219598162 0.04 ENSRNOT00000020297
leucine rich repeat containing 39
chr9_+_117538009 0.04 ENSRNOT00000022878
erythrocyte membrane protein band 4.1-like 3
chr2_+_239415046 0.04 ENSRNOT00000072196
CXXC finger protein 4
chr18_-_60002529 0.04 ENSRNOT00000081014
ENSRNOT00000024264
ENSRNOT00000059162
asparaginyl-tRNA synthetase
chr15_+_108318664 0.04 ENSRNOT00000057469
UBA domain containing 2
chr12_-_37538403 0.04 ENSRNOT00000001402
small nuclear ribonucleoprotein U11/U12 subunit 35
chr7_-_58365313 0.04 ENSRNOT00000005443
THAP domain containing 2
chr4_-_180234804 0.04 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr4_-_170932618 0.04 ENSRNOT00000007779
Rho GDP dissociation inhibitor beta
chr1_-_15374850 0.04 ENSRNOT00000016728
peroxisomal biogenesis factor 7
chr7_+_120923274 0.04 ENSRNOT00000049247
GTP binding protein 1
chr1_-_217631862 0.04 ENSRNOT00000078514
ENSRNOT00000079805
cortactin
chr2_-_33025271 0.04 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr12_-_23727535 0.04 ENSRNOT00000085911
ENSRNOT00000001950
deltex E3 ubiquitin ligase 2
chr4_-_66955732 0.04 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr1_-_228014924 0.04 ENSRNOT00000042091
oocyte secreted protein 2
chr12_-_45801842 0.04 ENSRNOT00000078837

chr2_-_186245342 0.04 ENSRNOT00000057062
ENSRNOT00000022292
doublecortin-like kinase 2
chr9_+_79630604 0.04 ENSRNOT00000021539
ENSRNOT00000083979
transmembrane protein 169
chr4_-_80395502 0.04 ENSRNOT00000014437
neuropeptide VF precursor
chr18_+_29951094 0.04 ENSRNOT00000027402
protocadherin alpha-1-like
chr8_+_22559098 0.04 ENSRNOT00000041091
hypothetical protein LOC691141
chr1_+_251633199 0.04 ENSRNOT00000084785

chr2_-_147392062 0.04 ENSRNOT00000021535
transmembrane 4 L six family member 1
chr7_-_120770435 0.03 ENSRNOT00000077000
DEAD-box helicase 17
chr17_-_78499881 0.03 ENSRNOT00000079260
family with sequence similarity 107, member B
chr20_+_19325121 0.03 ENSRNOT00000058151
phytanoyl-CoA 2-hydroxylase interacting protein-like
chrX_+_37329779 0.03 ENSRNOT00000038352
ENSRNOT00000088802
pyruvate dehydrogenase (lipoamide) alpha 1
chr19_+_46465647 0.03 ENSRNOT00000093714
nudix hydrolase 7
chr10_+_83476107 0.03 ENSRNOT00000075733
prohibitin
chr5_+_114516889 0.03 ENSRNOT00000011767
FGGY carbohydrate kinase domain containing
chr2_-_96509424 0.03 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr10_-_62184874 0.03 ENSRNOT00000004229
replication protein A1
chr16_-_29936307 0.03 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_+_153269526 0.03 ENSRNOT00000091494
SYF2 pre-mRNA-splicing factor
chr5_+_135354700 0.03 ENSRNOT00000021850
intracisternal A particle-promoted polypeptide
chr7_-_29171783 0.03 ENSRNOT00000079235
myosin binding protein C, slow type
chr13_+_84474319 0.03 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
immunoglobulin-like domain containing receptor 2
chr7_+_2752680 0.03 ENSRNOT00000033726
citrate synthase
chr2_-_123972356 0.03 ENSRNOT00000023348
interleukin 21
chr2_+_248398917 0.03 ENSRNOT00000045855
guanylate binding protein 1
chr18_+_70739492 0.03 ENSRNOT00000085601
acetyl-CoA acyltransferase 2
chrX_-_104932508 0.03 ENSRNOT00000075325
NADPH oxidase 1
chr16_+_46731403 0.03 ENSRNOT00000017624
teneurin transmembrane protein 3
chr5_+_139790395 0.03 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chrX_+_78042859 0.03 ENSRNOT00000003286
lysophosphatidic acid receptor 4
chr16_+_39145230 0.03 ENSRNOT00000092942
ADAM metallopeptidase domain 21
chr4_-_100252755 0.03 ENSRNOT00000017301
vesicle-associated membrane protein 8
chr3_+_7884822 0.03 ENSRNOT00000019157
mediator complex subunit 27
chr16_+_7758996 0.03 ENSRNOT00000061063
biotinidase
chr8_-_121973125 0.03 ENSRNOT00000012114
programmed cell death 6 interacting protein
chr13_+_90260783 0.03 ENSRNOT00000050547
CD84 molecule
chr1_+_213636093 0.02 ENSRNOT00000019642
proteasome 26S subunit, non-ATPase 13
chr5_-_17061361 0.02 ENSRNOT00000089318
proenkephalin
chr10_-_65502936 0.02 ENSRNOT00000089615
SPT6 homolog, histone chaperone
chr1_-_185569190 0.02 ENSRNOT00000090773
similar to sid2057p
chr10_+_83201311 0.02 ENSRNOT00000006179
solute carrier family 35, member B1
chr10_+_69412017 0.02 ENSRNOT00000009448
C-C motif chemokine ligand 2
chr11_+_47061354 0.02 ENSRNOT00000039997
PEST proteolytic signal containing nuclear protein
chr5_-_166116516 0.02 ENSRNOT00000079919
ENSRNOT00000080888
kinesin family member 1B
chr14_+_22375955 0.02 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr6_+_26241672 0.02 ENSRNOT00000006543
SPT7-like STAGA complex gamma subunit
chr16_+_25773602 0.02 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr13_+_49005405 0.02 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr4_-_146954159 0.02 ENSRNOT00000010397
TAM41 mitochondrial translocator assembly and maintenance homolog
chr8_-_78096302 0.02 ENSRNOT00000086185
ENSRNOT00000077999
myocardial zonula adherens protein
chr10_-_82117109 0.02 ENSRNOT00000079711
ATP binding cassette subfamily C member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc4_Arx_Otp_Esx1_Phox2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.2 0.6 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 1.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.9 GO:0032060 bleb assembly(GO:0032060)
0.1 0.2 GO:0021886 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375)
0.0 0.1 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.1 GO:0046154 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0032679 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.2 GO:0034475 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.1 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.0 0.1 GO:0099628 establishment of synaptic specificity at neuromuscular junction(GO:0007529) gamma-aminobutyric acid receptor clustering(GO:0097112) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0002003 angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.0 0.1 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.0 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0034031 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0099571 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008940 nitrate reductase activity(GO:0008940)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis