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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxb8_Pdx1

Z-value: 0.31

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Transcription factors associated with Hoxb8_Pdx1

Gene Symbol Gene ID Gene Info
ENSRNOG00000007585 homeo box B8
ENSRNOG00000046458 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb8rn6_v1_chr10_+_84131495_841314950.138.4e-01Click!

Activity profile of Hoxb8_Pdx1 motif

Sorted Z-values of Hoxb8_Pdx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_82133605 0.20 ENSRNOT00000008023
homeobox A2
chr10_+_84200880 0.13 ENSRNOT00000011213
homeobox B2
chr7_+_37812831 0.09 ENSRNOT00000005910
BTG anti-proliferation factor 1
chrX_+_136460215 0.09 ENSRNOT00000093538
Rho GTPase activating protein 36
chr14_+_39368530 0.08 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr3_+_159368273 0.08 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr5_-_2803855 0.08 ENSRNOT00000009490
ribosomal protein S8-like
chr11_+_80358211 0.08 ENSRNOT00000002519
somatostatin
chr7_-_145062956 0.07 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr3_+_160908769 0.07 ENSRNOT00000030054
Sys1 golgi trafficking protein
chr10_-_87407634 0.07 ENSRNOT00000016657
keratin 23
chr11_+_53140599 0.07 ENSRNOT00000083438
BBX, HMG-box containing
chr16_-_11214948 0.07 ENSRNOT00000023369
similar to 60S ribosomal protein L38
chrX_+_124894466 0.07 ENSRNOT00000080894
MCTS1, re-initiation and release factor
chr14_+_32257805 0.07 ENSRNOT00000039626

chr11_+_17538063 0.06 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr1_-_141655417 0.06 ENSRNOT00000068084
adaptor-related protein complex 3, sigma 2 subunit
chr14_-_62595854 0.05 ENSRNOT00000003024
Yip1 domain family, member 7
chr1_-_155955173 0.05 ENSRNOT00000079345

chr14_-_14390699 0.05 ENSRNOT00000046639
annexin A3
chr1_+_264893162 0.05 ENSRNOT00000021714
T-cell leukemia, homeobox 1
chrX_-_123486814 0.05 ENSRNOT00000016993
similar to hypothetical protein FLJ22965
chr19_-_37427989 0.05 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr9_+_53440272 0.05 ENSRNOT00000059159
hypothetical protein LOC685203
chr16_-_7412150 0.05 ENSRNOT00000047252
similar to ribosomal protein S24
chr2_+_212247451 0.05 ENSRNOT00000027813
vav guanine nucleotide exchange factor 3
chr5_-_22769907 0.05 ENSRNOT00000047805
ENSRNOT00000076167
ENSRNOT00000076507
ENSRNOT00000076113
ENSRNOT00000083779
aspartate-beta-hydroxylase
chr3_+_114900343 0.05 ENSRNOT00000068129
sulfide quinone reductase-like (yeast)
chr3_-_161131812 0.05 ENSRNOT00000067008
WAP four-disulfide core domain 11
chrX_+_119390013 0.05 ENSRNOT00000074269
angiotensin II receptor, type 2
chr14_-_72970329 0.05 ENSRNOT00000006325
protein phosphatase 2C-like domain containing 1
chr8_-_104155775 0.05 ENSRNOT00000042885
60S ribosomal protein L31-like
chrX_+_35869538 0.04 ENSRNOT00000058947
protein phosphatase with EF-hand domain 1
chrX_+_112311251 0.04 ENSRNOT00000086698

chr5_-_12172009 0.04 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chrX_+_124894706 0.04 ENSRNOT00000066677
MCTS1, re-initiation and release factor
chr4_-_159192526 0.04 ENSRNOT00000026731
potassium voltage-gated channel subfamily A member 1
chr10_-_18506337 0.04 ENSRNOT00000043036
gamma-aminobutyric acid type A receptor pi subunit
chr7_-_1738642 0.04 ENSRNOT00000075554

chr1_-_67094567 0.04 ENSRNOT00000073583

chr7_+_130542202 0.04 ENSRNOT00000079501
ENSRNOT00000045647
acrosin
chr5_-_164348713 0.04 ENSRNOT00000087044
similar to casein kinase 1, gamma 3 isoform 2
chr16_-_52127591 0.04 ENSRNOT00000033652
tripartite motif family-like 2
chr1_+_15834779 0.04 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr9_-_4685383 0.04 ENSRNOT00000061896
sulfotransferase family 1C member 2
chr4_+_166601960 0.04 ENSRNOT00000073394

chr8_+_99632803 0.04 ENSRNOT00000087190
phospholipid scramblase 1
chr3_-_45169118 0.04 ENSRNOT00000086371
coiled-coil domain containing 148
chr14_-_91979500 0.04 ENSRNOT00000073892
dopa decarboxylase
chr8_+_130350510 0.04 ENSRNOT00000073376
SS18 like 2
chr8_-_49227273 0.04 ENSRNOT00000050878
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr8_-_92942076 0.03 ENSRNOT00000056937
family with sequence similarity 46, member A
chr8_+_117906014 0.03 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chrX_-_45284341 0.03 ENSRNOT00000045436
odorant binding protein I f
chr4_-_132111079 0.03 ENSRNOT00000013719
eukaryotic translation initiation factor 4E family member 3
chr15_-_44442875 0.03 ENSRNOT00000017939
gonadotropin releasing hormone 1
chr9_+_15313523 0.03 ENSRNOT00000070805
translocase of outer mitochondrial membrane 6
chr18_-_85980833 0.03 ENSRNOT00000058179
suppressor of cytokine signaling 6
chr8_-_77599781 0.03 ENSRNOT00000087980
aquaporin 9
chr15_+_1054937 0.03 ENSRNOT00000008154

chr14_+_7949239 0.03 ENSRNOT00000044617
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4-like 1
chr15_+_28439317 0.03 ENSRNOT00000060519
similar to ribosomal protein L31
chrX_+_105134498 0.03 ENSRNOT00000002058
transmembrane protein 35
chr5_-_58106706 0.03 ENSRNOT00000019561
dynactin subunit 3
chrX_+_31984612 0.03 ENSRNOT00000005181
BMX non-receptor tyrosine kinase
chr17_+_69960160 0.03 ENSRNOT00000023887
urocortin 3
chrX_-_142248369 0.03 ENSRNOT00000091330
fibroblast growth factor 13
chr4_-_181348799 0.03 ENSRNOT00000033743
hypothetical protein LOC690783
chr10_-_87521514 0.03 ENSRNOT00000084668
ENSRNOT00000071705
keratin associated protein 2-4-like
chr2_+_210045161 0.03 ENSRNOT00000024455
solute carrier family 16, member 4
chr4_-_82263302 0.03 ENSRNOT00000082933
homeobox protein Hox-A6-like
chrX_+_54553878 0.03 ENSRNOT00000040231
spermatogenesis associated multipass transmembrane protein 3
chr8_-_77398156 0.03 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr10_-_87954055 0.03 ENSRNOT00000018048
keratin 34
chr13_-_36022197 0.03 ENSRNOT00000091280
cilia and flagella associated protein 221
chr6_-_127620296 0.03 ENSRNOT00000012577
serpin family A member 1
chr19_+_25983169 0.03 ENSRNOT00000004404
synaptonemal complex central element protein 2
chr4_-_58250798 0.03 ENSRNOT00000048436
Kruppel-like factor 14
chr14_-_72122158 0.03 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chr6_-_51018050 0.03 ENSRNOT00000082691
G protein-coupled receptor 22
chr2_-_259382765 0.03 ENSRNOT00000091407
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr2_-_123972356 0.03 ENSRNOT00000023348
interleukin 21
chr11_+_88376256 0.03 ENSRNOT00000081776
pre-B lymphocyte 1
chr3_-_47025128 0.03 ENSRNOT00000011682
RNA binding motif, single stranded interacting protein 1
chr3_-_61581598 0.03 ENSRNOT00000002156
even-skipped homeobox 2
chr1_-_1889236 0.03 ENSRNOT00000087944

chr2_-_252451999 0.03 ENSRNOT00000021861
deoxyribonuclease 2 beta
chr8_-_63291966 0.03 ENSRNOT00000077762

chr7_+_125288081 0.03 ENSRNOT00000085216
parvin, gamma
chr3_+_31802999 0.03 ENSRNOT00000041305

chr19_+_43163129 0.03 ENSRNOT00000073721
C-type lectin domain family 18, member A
chr3_-_23020441 0.02 ENSRNOT00000017651
nuclear receptor subfamily 5, group A, member 1
chr16_-_31301880 0.02 ENSRNOT00000084847
ENSRNOT00000083943

chr3_-_151363115 0.02 ENSRNOT00000073492
eukaryotic translation initiation factor 6
chr3_+_118317761 0.02 ENSRNOT00000012700
fibroblast growth factor 7
chr16_-_29936307 0.02 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_-_128446725 0.02 ENSRNOT00000011272
basic transcription factor 3-like 4
chr1_+_85485289 0.02 ENSRNOT00000026182
delta like canonical Notch ligand 3
chr5_+_133864798 0.02 ENSRNOT00000091977
TAL bHLH transcription factor 1, erythroid differentiation factor
chr7_-_144837583 0.02 ENSRNOT00000055289
chromobox 5
chrX_-_83864150 0.02 ENSRNOT00000073734
odorant binding protein I f
chr14_+_22107416 0.02 ENSRNOT00000060179
ENSRNOT00000080114
sulfotransferase family 1D, member 1
chr1_+_46978458 0.02 ENSRNOT00000024211
general transcription factor IIH subunit 5
chr13_+_108642156 0.02 ENSRNOT00000004783
SET and MYND domain containing 2
chr14_+_79013807 0.02 ENSRNOT00000091068
biogenesis of lysosomal organelles complex 1 subunit 4
chr18_-_81682206 0.02 ENSRNOT00000058219
hypothetical protein LOC100359752
chr4_-_162856663 0.02 ENSRNOT00000077791
C-type lectin domain family 2, member E
chr3_+_51883559 0.02 ENSRNOT00000007197
cysteine and serine rich nuclear protein 3
chr19_+_34616768 0.02 ENSRNOT00000051194
ribosomal protein S27a, pseudogene 6
chr7_+_117519075 0.02 ENSRNOT00000029768
scleraxis bHLH transcription factor
chr16_+_61926586 0.02 ENSRNOT00000058884

chr6_-_75670135 0.02 ENSRNOT00000007300
sorting nexin 6
chr10_+_46018659 0.02 ENSRNOT00000040865
ENSRNOT00000004357
myosin phosphatase Rho interacting protein
chr4_+_117594805 0.02 ENSRNOT00000074924
EKC/KEOPS complex subunit Tprkb
chr4_-_170860225 0.02 ENSRNOT00000007577
matrix Gla protein
chr17_-_71897972 0.02 ENSRNOT00000065942
Scm-like with four mbt domains 2
chr3_-_134696654 0.02 ENSRNOT00000006454
fibronectin leucine rich transmembrane protein 3
chr3_-_176548208 0.02 ENSRNOT00000084339
cholinergic receptor nicotinic alpha 4 subunit
chr20_-_25826658 0.02 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr1_+_84280945 0.02 ENSRNOT00000057190
SERTA domain containing 3
chr4_-_84131030 0.02 ENSRNOT00000012196
carboxypeptidase, vitellogenic-like
chr14_+_42007312 0.02 ENSRNOT00000063985
ATPase phospholipid transporting 8A1
chr2_+_240461505 0.02 ENSRNOT00000019507
3-hydroxybutyrate dehydrogenase 2
chr18_-_36893797 0.02 ENSRNOT00000043544
G protein-coupled receptor 151
chr12_-_13133219 0.02 ENSRNOT00000092292
diacylglycerol lipase, beta
chr9_+_67699379 0.02 ENSRNOT00000091237
ENSRNOT00000088183
cytotoxic T-lymphocyte-associated protein 4
chr4_+_57925323 0.02 ENSRNOT00000085798
carboxypeptidase A5
chr2_+_147496229 0.02 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr1_-_101095594 0.02 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr2_-_203680083 0.02 ENSRNOT00000021268
Cd2 molecule
chr17_-_90218013 0.02 ENSRNOT00000072803
inositol monophosphatase domain containing 1
chr16_+_61130755 0.02 ENSRNOT00000042609

chr8_-_27973980 0.02 ENSRNOT00000037757
beta-galactosidase-like protein
chr17_-_15519060 0.02 ENSRNOT00000093624
asporin-like 1
chr9_-_121972055 0.02 ENSRNOT00000089735
clusterin-like protein 1
chr2_-_210738378 0.02 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr1_+_61374379 0.02 ENSRNOT00000015343
zinc finger protein 53
chr9_+_94928489 0.02 ENSRNOT00000087366
ENSRNOT00000085770
ENSRNOT00000024733
S-antigen visual arrestin
chr14_+_19319299 0.02 ENSRNOT00000086542
ankyrin repeat domain 17
chr5_-_100970043 0.02 ENSRNOT00000013950
zinc finger, DHHC-type containing 21
chr5_+_133865331 0.02 ENSRNOT00000035409
TAL bHLH transcription factor 1, erythroid differentiation factor
chr20_+_47395014 0.02 ENSRNOT00000057116
osteopetrosis associated transmembrane protein 1
chr4_-_170740274 0.02 ENSRNOT00000012212
guanylate cyclase 2C
chr3_+_4867233 0.02 ENSRNOT00000006754
ribosomal protein L7a
chr5_-_50138475 0.02 ENSRNOT00000011969
solute carrier family 35 member A1
chr8_-_128521109 0.02 ENSRNOT00000034025
sodium voltage-gated channel alpha subunit 11
chr1_+_98425903 0.02 ENSRNOT00000024170
hypothetical protein LOC690483
chr4_+_14039977 0.02 ENSRNOT00000091249
ENSRNOT00000075878
CD36 molecule
chr11_+_86421106 0.02 ENSRNOT00000002599
serine/threonine-protein phosphatase 2A catalytic subunit alpha-like
chr4_-_164900857 0.02 ENSRNOT00000078690
Ly49 inhibitory receptor 2
chr5_+_8876044 0.02 ENSRNOT00000008877
COP9 signalosome subunit 5
chrM_+_11736 0.02 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr1_-_276012351 0.02 ENSRNOT00000045642

chrX_-_42329232 0.02 ENSRNOT00000045705
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr10_-_88107232 0.02 ENSRNOT00000019330
ENSRNOT00000076770
keratin 9
chr7_+_121930615 0.02 ENSRNOT00000091270
ENSRNOT00000033975
trinucleotide repeat containing 6B
chr4_-_148761547 0.02 ENSRNOT00000018050
zinc finger protein 422
chr5_+_165724027 0.02 ENSRNOT00000018000
castor zinc finger 1
chr4_-_132740938 0.02 ENSRNOT00000007185
RING1 and YY1 binding protein
chr16_+_70778913 0.02 ENSRNOT00000019281
hook microtubule-tethering protein 3
chr3_+_61658245 0.02 ENSRNOT00000033511
homeo box D3
chr15_+_18322327 0.02 ENSRNOT00000009650
family with sequence similarity 3, member D
chr7_-_18180705 0.02 ENSRNOT00000065954
zinc finger protein 494
chr20_-_5166252 0.02 ENSRNOT00000001138
allograft inflammatory factor 1
chr4_-_162230859 0.01 ENSRNOT00000042872
similar to osteoclast inhibitory lectin
chr3_+_160410757 0.01 ENSRNOT00000055172
poly(A) binding protein, cytoplasmic 1-like
chr1_+_167870452 0.01 ENSRNOT00000025027
olfactory receptor 63
chr2_+_62198562 0.01 ENSRNOT00000087636
zinc finger RNA binding protein
chr2_+_166856784 0.01 ENSRNOT00000035765
otolin 1
chr18_+_27632786 0.01 ENSRNOT00000073564
ENSRNOT00000078969
receptor accessory protein 2
chr12_-_19592000 0.01 ENSRNOT00000001855
galactose-3-O-sulfotransferase 4
chr2_+_55835151 0.01 ENSRNOT00000018634
FYN binding protein
chr4_-_23119005 0.01 ENSRNOT00000048061
STEAP4 metalloreductase
chr17_-_43537293 0.01 ENSRNOT00000091749
solute carrier family 17 member 3
chr6_-_67084234 0.01 ENSRNOT00000050372
NOVA alternative splicing regulator 1
chr6_-_10592454 0.01 ENSRNOT00000020600
phosphatidylinositol glycan anchor biosynthesis, class F
chr4_-_181348038 0.01 ENSRNOT00000082879
hypothetical protein LOC690783
chr8_+_132828091 0.01 ENSRNOT00000008269
C-C motif chemokine receptor 9
chr2_+_237679792 0.01 ENSRNOT00000064628
GIMAP family P-loop NTPase domain containing 1
chr5_-_25750826 0.01 ENSRNOT00000022249
family with sequence similarity 92 member A
chr12_-_50213400 0.01 ENSRNOT00000048541
trichohyalin-like
chr14_+_45062662 0.01 ENSRNOT00000059124
toll-like receptor 10
chrY_-_1398030 0.01 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked
chr5_+_137243094 0.01 ENSRNOT00000067237
mediator complex subunit 8
chr9_+_67774150 0.01 ENSRNOT00000091060
inducible T-cell co-stimulator
chr10_+_91217079 0.01 ENSRNOT00000004218
hexamethylene bis-acetamide inducible 2
chr19_-_43848937 0.01 ENSRNOT00000044844
lactate dehydrogenase D
chr1_+_100501676 0.01 ENSRNOT00000043724
family with sequence similarity 71, member E1
chr11_+_66713888 0.01 ENSRNOT00000003340
F-box protein 40
chr15_-_18096039 0.01 ENSRNOT00000042545
prostaglandin D2 receptor
chr7_-_29171783 0.01 ENSRNOT00000079235
myosin binding protein C, slow type
chr16_+_72010106 0.01 ENSRNOT00000058330
ADAM metallopeptidase domain 5
chr8_-_39734594 0.01 ENSRNOT00000076872
solute carrier family 37 member 2
chr10_-_8498422 0.01 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr1_-_85517360 0.01 ENSRNOT00000026114
EP300 interacting inhibitor of differentiation 2
chr3_+_122803772 0.01 ENSRNOT00000009564
NOP56 ribonucleoprotein
chr4_-_50312608 0.01 ENSRNOT00000010019
Fez family zinc finger 1
chr2_+_205488182 0.01 ENSRNOT00000024270
suppressor of IKBKE 1
chr2_-_172459165 0.01 ENSRNOT00000057473
schwannomin interacting protein 1
chr1_+_248723397 0.01 ENSRNOT00000072188
mannose-binding protein C-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb8_Pdx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.0 0.0 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0015265 urea channel activity(GO:0015265)