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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hoxb5
Z-value: 0.45
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Transcription factors associated with Hoxb5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hoxb5 | rn6_v1_chr10_+_84152152_84152152 | 0.39 | 5.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_6679878 Show fit | 0.58 |
ENSRNOT00000075989
ENSRNOT00000067875 |
secreted phosphoprotein 1 |
|
| chr2_+_164549455 Show fit | 0.22 |
ENSRNOT00000017151
|
myeloid leukemia factor 1 |
|
| chr20_+_5067330 Show fit | 0.15 |
ENSRNOT00000037482
|
lymphocyte antigen 6 complex, locus G6E |
|
| chr5_-_38923095 Show fit | 0.13 |
ENSRNOT00000009146
|
|
|
| chr12_-_38782010 Show fit | 0.12 |
ENSRNOT00000001813
|
WD repeat domain 66 |
|
| chr4_+_7173961 Show fit | 0.11 |
ENSRNOT00000017854
|
gastrulation brain homeobox 1 |
|
| chr10_-_13115294 Show fit | 0.11 |
ENSRNOT00000005899
|
FLYWCH family member 2 |
|
| chr12_+_2170630 Show fit | 0.10 |
ENSRNOT00000071928
|
PET100 homolog |
|
| chr10_-_83898527 Show fit | 0.10 |
ENSRNOT00000009815
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) |
|
| chr2_+_187740531 Show fit | 0.10 |
ENSRNOT00000092653
|
progestin and adipoQ receptor family member 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hoxb5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.0 | 0.2 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.0 | 0.1 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.0 | 0.1 | GO:0097374 | proprioception(GO:0019230) sensory neuron axon guidance(GO:0097374) |
| 0.0 | 0.1 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 0.0 | 0.1 | GO:0033386 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.0 | 0.1 | GO:0035772 | interleukin-13-mediated signaling pathway(GO:0035772) |
| 0.0 | 0.1 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623) |
| 0.0 | 0.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.1 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.1 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.0 | 0.1 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |