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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxb3

Z-value: 0.29

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Transcription factors associated with Hoxb3

Gene Symbol Gene ID Gene Info
ENSRNOG00000008313 homeo box B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb3rn6_v1_chr10_+_84182118_841821180.741.5e-01Click!

Activity profile of Hoxb3 motif

Sorted Z-values of Hoxb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_9855443 0.24 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chr10_-_88670430 0.13 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr17_+_11683862 0.12 ENSRNOT00000024766
msh homeobox 2
chr6_-_106971250 0.12 ENSRNOT00000010926
double PHD fingers 3
chr9_+_117795132 0.10 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr15_+_11298478 0.10 ENSRNOT00000007672
leucine rich repeat containing 3B
chr5_-_151459037 0.10 ENSRNOT00000064472
ENSRNOT00000087836
synaptotagmin-like 1
chr12_+_38965063 0.09 ENSRNOT00000074936
MORN repeat containing 3
chr10_+_103395511 0.09 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr16_+_54332660 0.09 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr1_-_184188911 0.08 ENSRNOT00000055124
ENSRNOT00000014948
calcitonin-related polypeptide alpha
chr17_-_43776460 0.07 ENSRNOT00000089055
histone cluster 2, H3c2
chr7_+_59200918 0.07 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr2_+_207262934 0.07 ENSRNOT00000016833
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr12_-_19167015 0.07 ENSRNOT00000001797
gap junction protein, gamma 3
chr1_+_184271590 0.07 ENSRNOT00000014764
calcitonin-related polypeptide, beta
chr4_-_82141385 0.05 ENSRNOT00000008447
homeobox A3
chr4_+_148782479 0.05 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr5_-_12526962 0.05 ENSRNOT00000092104
suppression of tumorigenicity 18
chr3_-_11417546 0.04 ENSRNOT00000018776
lipocalin 2
chr6_-_7058314 0.04 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr1_-_198450047 0.04 ENSRNOT00000027360
major vault protein
chr14_-_115052450 0.04 ENSRNOT00000067998
acylphosphatase 2
chr17_-_14627937 0.04 ENSRNOT00000020532
osteoglycin
chr9_-_16848503 0.04 ENSRNOT00000024815
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr2_+_188583664 0.03 ENSRNOT00000045477
dolichyl-phosphate mannosyltransferase subunit 3
chr12_-_52658275 0.03 ENSRNOT00000041981
zinc finger protein 605
chr20_+_7409401 0.03 ENSRNOT00000000586
small nuclear ribonucleoprotein polypeptide C
chr1_-_101085884 0.03 ENSRNOT00000085352
reticulocalbin 3
chr4_+_171748273 0.03 ENSRNOT00000009998
deoxyribose-phosphate aldolase
chr20_+_44680449 0.03 ENSRNOT00000000728
Traf3 interacting protein 2
chr7_-_83670356 0.03 ENSRNOT00000005584
syntabulin
chr19_-_37938857 0.03 ENSRNOT00000026730
solute carrier family 12 member 4
chr1_-_101086198 0.03 ENSRNOT00000027917
reticulocalbin 3
chr4_-_168656673 0.03 ENSRNOT00000009341
G protein-coupled receptor 19
chr14_-_29232537 0.03 ENSRNOT00000087499

chr1_-_252808380 0.03 ENSRNOT00000025856
cholesterol 25-hydroxylase
chr7_-_2712723 0.03 ENSRNOT00000004363
interleukin 23 subunit alpha
chr4_-_132296413 0.03 ENSRNOT00000052326
similar to macrophage migration inhibitory factor
chr6_-_44363915 0.03 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr20_+_1749716 0.03 ENSRNOT00000048856
olfactory receptor 1735
chr2_+_248398917 0.03 ENSRNOT00000045855
guanylate binding protein 1
chr12_+_24761210 0.03 ENSRNOT00000002003
claudin 4
chr16_+_74785281 0.03 ENSRNOT00000064316
ENSRNOT00000017106
ENSRNOT00000090646
NIMA-related kinase 3
chr4_+_117962319 0.02 ENSRNOT00000057441
transforming growth factor alpha
chrX_+_6273733 0.02 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr3_+_102925471 0.02 ENSRNOT00000040364
olfactory receptor 772
chr20_-_1099336 0.02 ENSRNOT00000071766
olfactory receptor-like protein-like
chr19_+_37873515 0.02 ENSRNOT00000026163
ENSRNOT00000089921
protein serine kinase H1
chr13_+_87966758 0.02 ENSRNOT00000079593
regulator of G-protein signaling 5
chr10_+_34402482 0.02 ENSRNOT00000072317
putative olfactory receptor
chr10_+_5199226 0.02 ENSRNOT00000003544
dexamethasone-induced transcript
chr5_+_14890408 0.02 ENSRNOT00000033116
SRY box 17
chrX_+_33884499 0.02 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr15_+_33108671 0.02 ENSRNOT00000015468
LDL receptor related protein 10
chr1_-_38538987 0.02 ENSRNOT00000090406
ENSRNOT00000071275
zinc finger protein 728-like
chr3_+_14889510 0.02 ENSRNOT00000080760
DAB2 interacting protein
chr8_-_19917396 0.02 ENSRNOT00000032963
olfactory receptor 1158
chrX_+_144994139 0.02 ENSRNOT00000071783
pre-mRNA-splicing factor CWC22 homolog
chr4_-_62860446 0.02 ENSRNOT00000015752
family with sequence similarity 180, member A
chr7_-_44121130 0.02 ENSRNOT00000005706
neurotensin
chr12_+_52397792 0.02 ENSRNOT00000085661
ENSRNOT00000056694
ENSRNOT00000056693
ENSRNOT00000056692
ENSRNOT00000081447
purinergic receptor P2X 2
chr17_-_22678253 0.02 ENSRNOT00000083122
LRRGT00112-like
chr9_-_121972055 0.02 ENSRNOT00000089735
clusterin-like protein 1
chr10_+_11046221 0.02 ENSRNOT00000005109
NmrA like redox sensor 1
chr1_-_226353611 0.02 ENSRNOT00000037624
diacylglycerol lipase, alpha
chr2_+_185846232 0.02 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr16_-_23156962 0.02 ENSRNOT00000018543
SH2 domain containing 4A
chr19_+_45938915 0.02 ENSRNOT00000065508
MON1 homolog B, secretory trafficking associated
chr5_-_154222702 0.02 ENSRNOT00000080069
proline-rich nuclear receptor coactivator 2
chr10_-_43931094 0.02 ENSRNOT00000039778
olfactory receptor 1415
chr1_-_101095594 0.02 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr19_-_49448072 0.02 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr12_-_11785493 0.02 ENSRNOT00000039687
zinc finger protein 498
chr1_+_64480929 0.02 ENSRNOT00000087016
olfactory receptor 1-like
chr8_-_113937097 0.02 ENSRNOT00000046816
NIMA-related kinase 11
chr2_+_187951344 0.02 ENSRNOT00000027123
signal sequence receptor, beta
chr2_+_148765412 0.02 ENSRNOT00000018248
ENSRNOT00000084662
selenoprotein T
chr16_+_7035241 0.02 ENSRNOT00000084977
NIMA-related kinase 4
chr5_-_151473750 0.02 ENSRNOT00000011357
transmembrane protein 222
chr3_-_102826379 0.02 ENSRNOT00000073423
olfactory receptor 769
chr16_+_84465656 0.02 ENSRNOT00000043188
LRRGT00175
chr20_-_11721838 0.02 ENSRNOT00000001636
ubiquitin-conjugating enzyme E2G 2
chr4_-_174180729 0.02 ENSRNOT00000011376
phospholipase C, zeta 1
chr4_-_176909075 0.02 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr14_+_76732650 0.02 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chr7_-_83701447 0.01 ENSRNOT00000088893

chr5_-_154223536 0.01 ENSRNOT00000012258
proline-rich nuclear receptor coactivator 2
chr16_-_29936307 0.01 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr4_-_165026414 0.01 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr1_-_189182306 0.01 ENSRNOT00000021249
glycoprotein 2
chr8_-_114617466 0.01 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr12_-_50400765 0.01 ENSRNOT00000071613
crystallin, beta B1
chr10_-_81587858 0.01 ENSRNOT00000003582
UTP18 small subunit processome component
chr18_+_30581530 0.01 ENSRNOT00000048166
protocadherin beta 20
chr5_+_107712579 0.01 ENSRNOT00000090739
methylthioadenosine phosphorylase
chr1_+_169590308 0.01 ENSRNOT00000023147
olfactory receptor 155
chr17_+_9797907 0.01 ENSRNOT00000021638
lectin, mannose-binding 2
chr3_-_44501115 0.01 ENSRNOT00000087071
activin A receptor type 1
chr8_+_128792707 0.01 ENSRNOT00000083329
solute carrier family 25, member 38
chr12_-_31249118 0.01 ENSRNOT00000058586
ENSRNOT00000073105
adhesion G protein-coupled receptor D1
chr2_-_158133861 0.01 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr1_-_220938814 0.01 ENSRNOT00000028081
ovo like transcriptional repressor 1
chr10_-_90127600 0.01 ENSRNOT00000028368
LSM12 homolog
chr16_+_51748970 0.01 ENSRNOT00000059182
a disintegrin and metallopeptidase domain 26A
chr1_+_88113445 0.01 ENSRNOT00000056955
gametogenetin
chr4_-_21920651 0.01 ENSRNOT00000066211
transmembrane protein 243
chr2_+_4989295 0.01 ENSRNOT00000041541
family with sequence similarity 172, member A
chr1_-_261179790 0.01 ENSRNOT00000074420
ENSRNOT00000072073
exosome component 1
chr1_-_189181901 0.01 ENSRNOT00000092022
glycoprotein 2
chr20_+_6211420 0.01 ENSRNOT00000000624
potassium channel tetramerization domain containing 20
chr4_-_164406146 0.01 ENSRNOT00000090110
killer cell lectin-like receptor subfamily A, member 22
chr1_-_61686944 0.01 ENSRNOT00000059638
vomeronasal 1 receptor 23
chr12_-_35979193 0.01 ENSRNOT00000071104
transmembrane protein 132B
chr2_+_196120580 0.01 ENSRNOT00000068528
regulatory factor X5
chr3_-_124879216 0.01 ENSRNOT00000028886
transmembrane protein 230
chr14_+_22517774 0.01 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr17_+_76002275 0.01 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr18_-_25997555 0.01 ENSRNOT00000027755
StAR-related lipid transfer domain containing 4
chr2_-_209001895 0.01 ENSRNOT00000055960
similar to Hypothetical protein MGC58999
chr8_+_128027958 0.01 ENSRNOT00000045049
acetyl-Coenzyme A acyltransferase 1B
chr1_-_84168044 0.01 ENSRNOT00000084586
ENSRNOT00000028348
Sh3kbp1 binding protein 1
chr20_+_1809078 0.01 ENSRNOT00000084853
olfactory receptor 1739
chr4_+_68635581 0.01 ENSRNOT00000016217
single stranded DNA binding protein 1
chr1_-_99135977 0.01 ENSRNOT00000056515
vomeronasal 2 receptor, 38
chr19_-_42180362 0.01 ENSRNOT00000089515
polyamine modulated factor 1 binding protein 1
chr14_-_16903242 0.01 ENSRNOT00000003001
shroom family member 3
chr9_-_113328428 0.01 ENSRNOT00000086340
VAMP associated protein A
chr20_+_45458558 0.01 ENSRNOT00000000713
cyclin-dependent kinase 19
chr12_+_19328957 0.01 ENSRNOT00000033288
canopy FGF signaling regulator 4
chr15_+_87722221 0.01 ENSRNOT00000082688
sciellin
chr4_-_88684415 0.01 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)
chr7_+_38900593 0.01 ENSRNOT00000072166
epiphycan
chr20_+_1736377 0.01 ENSRNOT00000047035
olfactory receptor 1734
chr12_-_43940798 0.01 ENSRNOT00000001485
similar to hypothetical protein FLJ21415
chrX_-_29556610 0.01 ENSRNOT00000068113
trafficking protein particle complex 2
chr4_+_149970237 0.01 ENSRNOT00000019529
heterogeneous nuclear ribonucleoprotein F
chr4_-_165317573 0.01 ENSRNOT00000087529
ENSRNOT00000080017
killer cell lectin-like receptor, subfamily A, member 5
chr10_+_91200874 0.01 ENSRNOT00000004272
hexamethylene bis-acetamide inducible 1
chr1_-_206394346 0.01 ENSRNOT00000038122
hypothetical LOC100302465
chr20_-_3344286 0.01 ENSRNOT00000091505
protein phosphatase 1, regulatory subunit 10
chr17_+_2690062 0.01 ENSRNOT00000024937
olfactory receptor 1653
chr8_+_116318963 0.01 ENSRNOT00000036556
tumor suppressor candidate 2
chr1_-_178367828 0.01 ENSRNOT00000050823

chr11_+_74057361 0.01 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr12_-_47438931 0.01 ENSRNOT00000050782
similar to RIKEN cDNA 2210016L21 gene
chr8_-_46694613 0.01 ENSRNOT00000084514

chr10_+_61685645 0.01 ENSRNOT00000003933
MAX network transcriptional repressor
chrX_+_110016995 0.01 ENSRNOT00000093542
Nik related kinase
chr3_+_3389612 0.01 ENSRNOT00000041984
ribosomal protein L8
chr19_+_653510 0.01 ENSRNOT00000048221
NEDD8 activating enzyme E1 subunit 1
chr18_+_16544508 0.01 ENSRNOT00000020601
elongator acetyltransferase complex subunit 2
chr1_+_16819170 0.01 ENSRNOT00000019734
ENSRNOT00000086756
HBS1-like translational GTPase
chr10_-_34361212 0.01 ENSRNOT00000072557
olfactory receptor 1385
chr18_+_63203063 0.01 ENSRNOT00000024144
PRELI domain containing 3A
chr4_+_3959640 0.01 ENSRNOT00000009439
PAX interacting protein 1
chr14_-_7863664 0.01 ENSRNOT00000061162
protein tyrosine phosphatase, non-receptor type 13
chr2_+_23385183 0.01 ENSRNOT00000014860
arylsulfatase B
chr4_+_139670092 0.01 ENSRNOT00000008879
leucine rich repeat neuronal 1
chr7_+_15628665 0.01 ENSRNOT00000071081
olfactory receptor 1091
chr5_+_28485619 0.01 ENSRNOT00000093341
ENSRNOT00000093129
uncharacterized LOC100912373
chr1_+_80279706 0.01 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr6_-_104290579 0.01 ENSRNOT00000066014
enhancer of rudimentary homolog (Drosophila)
chr9_+_44491177 0.01 ENSRNOT00000075242
mitochondrial ribosomal protein L30
chr1_-_84008293 0.01 ENSRNOT00000002053
small nuclear ribonucleoprotein polypeptide A
chr11_+_82415995 0.01 ENSRNOT00000051772

chr9_+_98438439 0.01 ENSRNOT00000027220
selenocysteine lyase
chr13_-_79899479 0.00 ENSRNOT00000035815
similar to hypothetical protein
chr20_-_2224463 0.00 ENSRNOT00000001019
tripartite motif-containing 26
chr10_+_55492404 0.00 ENSRNOT00000005588
ENSRNOT00000078038
ribosomal protein L26
chr8_-_12355091 0.00 ENSRNOT00000009318
centrosomal protein 57
chr10_-_5344121 0.00 ENSRNOT00000003479
nucleotide binding protein 1
chr17_+_11856525 0.00 ENSRNOT00000014546
serine palmitoyltransferase, long chain base subunit 1
chr2_+_257626383 0.00 ENSRNOT00000080993
zinc finger, ZZ-type containing 3
chr1_+_255579474 0.00 ENSRNOT00000024465
B-TFIID TATA-box binding protein associated factor 1
chr6_+_80108655 0.00 ENSRNOT00000006137
gem (nuclear organelle) associated protein 2
chr10_-_34333305 0.00 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr12_-_11175917 0.00 ENSRNOT00000079573
zinc finger with KRAB and SCAN domains 5
chr1_-_198104109 0.00 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr1_+_229416489 0.00 ENSRNOT00000028617
olfactory receptor 336
chr8_-_59239954 0.00 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr11_-_62067655 0.00 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr5_+_78384444 0.00 ENSRNOT00000034978
similar to hypothetical protein 4933430I17
chr1_+_190200324 0.00 ENSRNOT00000001933
ATP-binding cassette, subfamily A (ABC1), member 16
chr18_-_43945273 0.00 ENSRNOT00000088900
DTW domain containing 2
chr8_+_117820538 0.00 ENSRNOT00000028075
coiled-coil domain containing 51
chr10_+_14519164 0.00 ENSRNOT00000079543
ENSRNOT00000046884
coiled-coil domain containing 154
chr4_+_78618737 0.00 ENSRNOT00000043790
diamine oxidase-like protein 2
chr1_-_100926335 0.00 ENSRNOT00000020304
adaptor-related protein complex 2, alpha 1 subunit
chr20_+_31761405 0.00 ENSRNOT00000000661
neurogenin 3
chr5_+_36566783 0.00 ENSRNOT00000077650
F-box and leucine-rich repeat protein 4
chr14_-_45859908 0.00 ENSRNOT00000086994
phosphoglucomutase 2
chr3_-_56113857 0.00 ENSRNOT00000011303
methyltransferase like 5
chr7_+_99609191 0.00 ENSRNOT00000012883
squalene epoxidase
chr17_-_55300998 0.00 ENSRNOT00000064331
supervillin
chr16_+_85331866 0.00 ENSRNOT00000019615
DNA ligase 4
chr5_+_187312 0.00 ENSRNOT00000030857
zinc finger protein 120-like
chr7_+_117456039 0.00 ENSRNOT00000051754
maestro heat-like repeat family member 1
chr5_-_161981441 0.00 ENSRNOT00000020316
podoplanin
chr11_-_81757813 0.00 ENSRNOT00000002462
DnaJ heat shock protein family (Hsp40) member B11

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)