Project
GSE49485: Hypoxia transcriptome sequencing of rat brain.
Navigation
Downloads
Results for Hoxb2_Dlx2
Z-value: 0.51
Motif logo
Transcription factors associated with Hoxb2_Dlx2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hoxb2 | rn6_v1_chr10_+_84200880_84200880 | 0.80 | 1.1e-01 | Click! |
| Dlx2 | rn6_v1_chr3_-_58181971_58181971 | 0.12 | 8.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_2174131 Show fit | 1.87 |
ENSRNOT00000001313
|
Purkinje cell protein 2 |
|
| chr3_-_66417741 Show fit | 1.09 |
ENSRNOT00000007662
|
neuronal differentiation 1 |
|
| chr10_-_88670430 Show fit | 0.42 |
ENSRNOT00000025547
|
hypocretin neuropeptide precursor |
|
| chr12_-_17186679 Show fit | 0.41 |
ENSRNOT00000001730
|
UNC homeobox |
|
| chr2_+_145174876 Show fit | 0.40 |
ENSRNOT00000040631
|
mab-21 like 1 |
|
| chr4_+_94696965 Show fit | 0.36 |
ENSRNOT00000064696
|
glutamate ionotropic receptor delta type subunit 2 |
|
| chr17_+_11683862 Show fit | 0.30 |
ENSRNOT00000024766
|
msh homeobox 2 |
|
| chr6_-_125723732 Show fit | 0.22 |
ENSRNOT00000084815
|
fibulin 5 |
|
| chr2_-_185852759 Show fit | 0.22 |
ENSRNOT00000049461
|
mab-21 like 2 |
|
| chr3_+_95715193 Show fit | 0.21 |
ENSRNOT00000089525
|
paired box 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hoxb2_Dlx2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.2 | 1.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.1 | 0.4 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.1 | 0.4 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.4 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 0.3 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.1 | 0.2 | GO:0003322 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
| 0.1 | 0.2 | GO:0060764 | cell-cell signaling involved in mammary gland development(GO:0060764) |
| 0.0 | 0.2 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.2 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 0.1 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.0 | 0.1 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.1 | GO:1990005 | granular vesicle(GO:1990005) |
| 0.0 | 0.1 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.0 | 0.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.4 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.0 | 0.2 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.0 | 0.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 0.1 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
| 0.0 | 0.1 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 0.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.0 | 0.0 | GO:0008940 | nitrate reductase activity(GO:0008940) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |