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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa9_Hoxb9

Z-value: 0.60

Motif logo

Transcription factors associated with Hoxa9_Hoxb9

Gene Symbol Gene ID Gene Info
ENSRNOG00000048146 homeobox A9
ENSRNOG00000007573 homeo box B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb9rn6_v1_chr10_+_84119884_84119884-0.326.0e-01Click!

Activity profile of Hoxa9_Hoxb9 motif

Sorted Z-values of Hoxa9_Hoxb9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_14360555 0.44 ENSRNOT00000065460
hypothetical gene supported by AF152002
chr14_+_39368530 0.24 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr9_-_7891514 0.17 ENSRNOT00000072684
protection of telomeres 1B
chr6_+_93563446 0.15 ENSRNOT00000050558
ENSRNOT00000011056
similar to Protein KIAA0586
chr20_-_3401273 0.14 ENSRNOT00000089257
ENSRNOT00000078451
ENSRNOT00000001085
nurim (nuclear envelope membrane protein)
chr9_+_66888393 0.13 ENSRNOT00000023536
calcium responsive transcription factor
chr4_-_129515435 0.13 ENSRNOT00000039353
EGF domain specific O-linked N-acetylglucosamine transferase
chr2_-_231409496 0.13 ENSRNOT00000055615
ENSRNOT00000015386
ENSRNOT00000068415
ankyrin 2
chr4_-_22424862 0.12 ENSRNOT00000082359
ATP binding cassette subfamily B member 1A
chr2_-_231409988 0.11 ENSRNOT00000080637
ENSRNOT00000037255
ENSRNOT00000074002
ankyrin 2
chr9_-_95108739 0.10 ENSRNOT00000070819
ubiquitin specific peptidase 40
chr8_-_69466618 0.10 ENSRNOT00000042925
iduronate 2-sulfatase
chr3_-_61488696 0.10 ENSRNOT00000083045
lunapark, ER junction formation factor
chr2_+_23289374 0.10 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr10_+_106712127 0.10 ENSRNOT00000040629
trinucleotide repeat containing 6C
chr1_+_234252757 0.10 ENSRNOT00000091814
RAR-related orphan receptor B
chr3_-_60166013 0.10 ENSRNOT00000024922
WAS/WASL interacting protein family, member 1
chr9_+_66889028 0.09 ENSRNOT00000087194
calcium responsive transcription factor
chr16_+_22361998 0.08 ENSRNOT00000016193
solute carrier family 18 member A1
chr17_+_45078556 0.08 ENSRNOT00000088280
zinc finger protein 192
chr18_+_30864216 0.08 ENSRNOT00000027015
protocadherin gamma subfamily A, 7
chr9_+_65534704 0.08 ENSRNOT00000016730
CASP8 and FADD-like apoptosis regulator
chr1_-_198900375 0.08 ENSRNOT00000024969
zinc finger protein 689
chr12_+_6403940 0.08 ENSRNOT00000083484
beta 3-glucosyltransferase
chr10_+_65552897 0.08 ENSRNOT00000056217
sperm associated antigen 5
chr18_-_75207306 0.08 ENSRNOT00000021717
SET binding protein 1
chr17_-_53713408 0.08 ENSRNOT00000022445
AT-rich interactive domain-containing protein 4B-like
chr16_+_31734944 0.08 ENSRNOT00000059673
palladin, cytoskeletal associated protein
chr5_-_154965027 0.08 ENSRNOT00000080881
ENSRNOT00000055992
lysine demethylase 1A
chr14_+_69800156 0.07 ENSRNOT00000072746
ligand dependent nuclear receptor corepressor-like
chr2_+_197715761 0.07 ENSRNOT00000083069
golgi phosphoprotein 3-like
chr9_+_66058047 0.07 ENSRNOT00000071819
cyclin-dependent kinase 15
chr12_+_19231092 0.07 ENSRNOT00000045379
zinc finger with KRAB and SCAN domains 1
chrX_-_70978714 0.07 ENSRNOT00000076336
solute carrier family 7 member 3
chr20_+_41266566 0.07 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr10_-_58771908 0.07 ENSRNOT00000018808
similar to 4933427D14Rik protein
chr2_-_31753528 0.07 ENSRNOT00000075057
phosphoinositide-3-kinase regulatory subunit 1
chr3_+_108795235 0.07 ENSRNOT00000007028
sprouty-related, EVH1 domain containing 1
chr14_-_20920286 0.06 ENSRNOT00000004391
solute carrier family 4 member 4
chr2_+_231941794 0.06 ENSRNOT00000091475

chr16_-_3762877 0.06 ENSRNOT00000052224
double homeobox B-like 1
chr1_+_61786900 0.06 ENSRNOT00000090287

chr3_+_9366053 0.06 ENSRNOT00000073999
fibrinogen C domain containing 1-like 1
chr15_-_93748742 0.06 ENSRNOT00000093370
MYC binding protein 2, E3 ubiquitin protein ligase
chr9_-_52238564 0.06 ENSRNOT00000005073
collagen type V alpha 2 chain
chr6_-_91250138 0.06 ENSRNOT00000052408
ninein-like
chr7_-_101138860 0.06 ENSRNOT00000077137

chr2_+_55835151 0.06 ENSRNOT00000018634
FYN binding protein
chr15_-_61648267 0.06 ENSRNOT00000071805
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr7_+_44146237 0.06 ENSRNOT00000058842
Ras association domain family member 9
chr1_-_87825333 0.06 ENSRNOT00000072689
zinc finger protein 74
chr10_-_16731898 0.05 ENSRNOT00000028186
CREB3 regulatory factor
chr10_-_70337532 0.05 ENSRNOT00000055963
schlafen family member 13
chr12_+_51960262 0.05 ENSRNOT00000084214
E1A binding protein p400
chr1_+_99616447 0.05 ENSRNOT00000029197
kallikrein related-peptidase 14
chr2_+_22910236 0.05 ENSRNOT00000078266
homer scaffolding protein 1
chr20_-_6257604 0.05 ENSRNOT00000092489
serine/threonine kinase 38
chr8_+_82037977 0.05 ENSRNOT00000082288
myosin VA
chr14_+_8080275 0.04 ENSRNOT00000065965
ENSRNOT00000092542
mitogen activated protein kinase 10
chr14_+_8080565 0.04 ENSRNOT00000092395
mitogen activated protein kinase 10
chr2_-_54963448 0.04 ENSRNOT00000017886
prostaglandin E receptor 4
chr6_+_30074303 0.04 ENSRNOT00000070908
family with sequence similarity 228, member A
chr10_-_87954055 0.04 ENSRNOT00000018048
keratin 34
chr8_-_109560747 0.04 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_15996958 0.04 ENSRNOT00000039726
archaelysin family metallopeptidase 1
chr9_-_11027506 0.04 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr10_-_91661558 0.04 ENSRNOT00000043156

chr3_+_67538289 0.04 ENSRNOT00000009839
DnaJ heat shock protein family (Hsp40) member C10
chr18_+_30880020 0.04 ENSRNOT00000060468
protocadherin gamma subfamily B, 5
chr8_+_82878941 0.04 ENSRNOT00000014846
bone morphogenetic protein 5
chr2_-_173087648 0.04 ENSRNOT00000091079
IQ motif containing J
chr17_+_42168263 0.04 ENSRNOT00000047422
ribosomal protein L37-like
chr2_-_197814808 0.04 ENSRNOT00000074156
ADAMTS-like 4
chr2_+_257633425 0.04 ENSRNOT00000071770
zinc finger, ZZ-type containing 3
chr13_+_44424689 0.04 ENSRNOT00000005206
aminocarboxymuconate semialdehyde decarboxylase
chr3_+_9998458 0.04 ENSRNOT00000012927
fibrinogen C domain containing 1
chr3_-_40477754 0.04 ENSRNOT00000091168

chr7_-_59547174 0.04 ENSRNOT00000085836
CCR4-NOT transcription complex, subunit 2
chrM_+_3904 0.04 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr5_+_117586103 0.04 ENSRNOT00000084640
ubiquitin specific peptidase 1
chr13_+_113373578 0.04 ENSRNOT00000009900
plexin A2
chr13_+_56513286 0.04 ENSRNOT00000015596
zinc finger and BTB domain containing 41
chr5_+_74766636 0.03 ENSRNOT00000030913

chr8_+_64610952 0.03 ENSRNOT00000015963
myosin IXA
chr4_-_168517177 0.03 ENSRNOT00000009151
dual specificity phosphatase 16
chr17_+_5311274 0.03 ENSRNOT00000067020
spermatogenesis-associated protein 31D1-like
chr4_-_148437961 0.03 ENSRNOT00000082907
arachidonate 5-lipoxygenase
chr2_+_257626383 0.03 ENSRNOT00000080993
zinc finger, ZZ-type containing 3
chr16_-_74700815 0.03 ENSRNOT00000081297
thrombospondin type 1 domain containing 1
chr13_-_71276497 0.03 ENSRNOT00000029773
regulator of G-protein signaling like 1
chr4_+_182483194 0.03 ENSRNOT00000002528
fatty acyl CoA reductase 2
chr16_+_32457521 0.03 ENSRNOT00000083579
chloride voltage-gated channel 3
chr2_-_196270826 0.03 ENSRNOT00000028609
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
chr2_-_22096949 0.03 ENSRNOT00000089325
zinc finger FYVE-type containing 16
chr5_-_64818813 0.03 ENSRNOT00000009111
ENSRNOT00000086505
aldolase, fructose-bisphosphate B
chr18_+_59748444 0.03 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr7_-_143228060 0.03 ENSRNOT00000088923
ENSRNOT00000012640
keratin 75
chr9_+_111233147 0.03 ENSRNOT00000056439
diphosphoinositol pentakisphosphate kinase 2
chr3_-_177095597 0.03 ENSRNOT00000029386
sterile alpha motif domain containing 10
chr1_+_154131926 0.03 ENSRNOT00000035257
ferritin light chain 1-like
chr8_-_63750531 0.03 ENSRNOT00000009496
neogenin 1
chr8_-_102149912 0.03 ENSRNOT00000011263
similar to Ab2-095
chr19_-_22194740 0.03 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr3_-_7796385 0.03 ENSRNOT00000082489
netrin G2
chr9_-_91100482 0.02 ENSRNOT00000064642
ubiquitin carboxyl-terminal hydrolase 40-like
chr2_+_243840134 0.02 ENSRNOT00000093355
eukaryotic translation initiation factor 4E
chr4_-_150829913 0.02 ENSRNOT00000041571
calcium voltage-gated channel subunit alpha1 C
chr6_+_76745981 0.02 ENSRNOT00000076784
breast cancer metastasis-suppressor 1-like
chr4_-_150829741 0.02 ENSRNOT00000051846
ENSRNOT00000052017
calcium voltage-gated channel subunit alpha1 C
chr5_-_164502469 0.02 ENSRNOT00000051887
RGD1565622
chr19_+_39063998 0.02 ENSRNOT00000081116
hyaluronan synthase 3
chr2_+_30360100 0.02 ENSRNOT00000024456
survival of motor neuron 1, telomeric
chr4_+_25635765 0.02 ENSRNOT00000009340
GTP binding protein 10
chr4_+_57925323 0.02 ENSRNOT00000085798
carboxypeptidase A5
chr19_+_9895121 0.02 ENSRNOT00000033953
protease, serine, 54
chr2_-_185005572 0.02 ENSRNOT00000093291
family with sequence similarity 160, member A1
chr1_+_242959488 0.02 ENSRNOT00000015668
dedicator of cytokinesis 8
chr8_+_102304095 0.02 ENSRNOT00000011358
solute carrier family 9 member A9
chr9_+_20048121 0.02 ENSRNOT00000014791
meprin 1 subunit alpha
chr1_-_193700673 0.02 ENSRNOT00000071314
polyadenylate-binding protein-interacting protein 2-like 1
chr7_+_123364312 0.02 ENSRNOT00000056048
coiled-coil domain containing 134
chr2_-_21437193 0.02 ENSRNOT00000084002
creatine kinase, mitochondrial 2
chr1_-_163117235 0.02 ENSRNOT00000019370
calpain 5
chr3_+_138174054 0.02 ENSRNOT00000007946
barrier to autointegration factor 2
chr1_+_204959174 0.02 ENSRNOT00000023257
zinc finger RANBP2-type containing 1
chr1_+_93242050 0.02 ENSRNOT00000013741
similar to 60S ribosomal protein L27a
chr20_-_4542073 0.02 ENSRNOT00000000477
complement factor B
chr1_+_277355619 0.02 ENSRNOT00000022788
NHL repeat containing 2
chr4_+_56981283 0.01 ENSRNOT00000010989
tetraspanin 33
chr4_+_68849033 0.01 ENSRNOT00000016912
maltase-glucoamylase
chr8_+_44136496 0.01 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr16_-_48692476 0.01 ENSRNOT00000013118
interferon regulatory factor 2
chr6_-_26314844 0.01 ENSRNOT00000006658
zinc finger protein 512
chr5_-_24489468 0.01 ENSRNOT00000081395
integrator complex subunit 8
chr18_-_57866741 0.01 ENSRNOT00000025790
F-box protein 38
chr17_-_18590536 0.01 ENSRNOT00000078992
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr8_+_107508351 0.01 ENSRNOT00000081594
centrosomal protein 70
chr4_+_178617401 0.01 ENSRNOT00000042619

chr14_-_115391652 0.01 ENSRNOT00000002094
ChaC cation transport regulator 2
chr10_-_87529599 0.01 ENSRNOT00000074099
keratin associated protein 2-1
chr10_+_53621375 0.01 ENSRNOT00000004147
myosin heavy chain 3
chr15_-_48284548 0.01 ENSRNOT00000038336
homeobox containing 1
chr8_-_60570058 0.01 ENSRNOT00000009169
S-phase cyclin A-associated protein in the ER
chr5_+_57657909 0.01 ENSRNOT00000073017
similar to ribosomal protein S13
chr10_+_39655455 0.01 ENSRNOT00000058817
acyl-CoA synthetase long-chain family member 6
chr3_+_93648343 0.01 ENSRNOT00000091164

chr1_+_114679537 0.01 ENSRNOT00000019498
OCA2 melanosomal transmembrane protein
chr4_-_178441547 0.01 ENSRNOT00000087434
ENSRNOT00000055542
SRY box 5
chr16_-_69176036 0.01 ENSRNOT00000018369
proline synthetase co-transcribed homolog (bacterial)
chr18_-_35780519 0.01 ENSRNOT00000079667
mutated in colorectal cancers
chr2_-_250862419 0.01 ENSRNOT00000017943
chloride channel accessory 4
chr1_+_229642412 0.01 ENSRNOT00000017109
leupaxin
chr6_-_38007162 0.01 ENSRNOT00000044583

chr10_-_88019967 0.01 ENSRNOT00000047580
keratin 36
chr8_+_130009573 0.01 ENSRNOT00000026106
trafficking kinesin protein 1
chr7_-_101138373 0.01 ENSRNOT00000043257
Ab1-152
chr2_+_248398917 0.01 ENSRNOT00000045855
guanylate binding protein 1
chr3_+_111298713 0.00 ENSRNOT00000043677
developmental pluripotency-associated 3
chr16_-_81693000 0.00 ENSRNOT00000092353
lysosomal-associated membrane protein 1
chr19_+_6046665 0.00 ENSRNOT00000084126
cadherin 8
chr14_-_28967980 0.00 ENSRNOT00000048175
adhesion G protein-coupled receptor L3
chr13_+_90260783 0.00 ENSRNOT00000050547
CD84 molecule
chr3_-_154490851 0.00 ENSRNOT00000017213
TELO2 interacting protein 1
chr10_-_66848388 0.00 ENSRNOT00000018891
oligodendrocyte-myelin glycoprotein
chr5_-_113880911 0.00 ENSRNOT00000029441
equatorin
chr1_-_220136470 0.00 ENSRNOT00000026812
actinin alpha 3
chr3_-_21904133 0.00 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr3_+_140024043 0.00 ENSRNOT00000086409
Ras and Rab interactor 2
chr18_-_11789697 0.00 ENSRNOT00000077304
ENSRNOT00000064554
desmocollin 3
chr14_-_84662143 0.00 ENSRNOT00000057529
ENSRNOT00000080078
HORMA domain containing 2
chr11_+_85508300 0.00 ENSRNOT00000038646

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:1905231 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.0 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0021502 neural fold elevation formation(GO:0021502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)