ISMARA results: Hoxa7

Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa7_Hoxc8

Z-value: 0.47

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Transcription factors associated with Hoxa7_Hoxc8

Gene Symbol	Gene ID	Gene Info
Hoxa7 NCBI RGD Ensembl	ENSRNOG00000049858	homeobox A7
Hoxc8 NCBI RGD Ensembl	ENSRNOG00000028619	homeobox C8

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Hoxa7	rn6_v1_chr4_-_82271893_82271893	0.57	3.2e-01	Click!
Hoxc8	rn6_v1_chr7_+_144605058_144605058	-0.47	4.3e-01	Click!

Activity profile of Hoxa7_Hoxc8 motif

Sorted Z-values of Hoxa7_Hoxc8 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr18_+_14757679 Show fit	0.22	ENSRNOT00000071364	Mapre2 NCBI RGD Ensembl Show fit	microtubule-associated protein, RP/EB family, member 2
chr1_+_141767940 Show fit	0.21	ENSRNOT00000064034	Zfp710 NCBI RGD Ensembl Show fit	zinc finger protein 710
chr2_-_33025271 Show fit	0.14	ENSRNOT00000074941	NEWGENE_1310139 NCBI RGD Ensembl Show fit	microtubule associated serine/threonine kinase family member 4
chr10_+_61685645 Show fit	0.13	ENSRNOT00000003933	Mnt NCBI RGD Ensembl Show fit	MAX network transcriptional repressor
chr6_+_64789940 Show fit	0.13	ENSRNOT00000085979 ENSRNOT00000059739 ENSRNOT00000051908 ENSRNOT00000082793 ENSRNOT00000078583 ENSRNOT00000091677 ENSRNOT00000093241	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule
chr5_+_25725683 Show fit	0.13	ENSRNOT00000087602	LOC679087 NCBI RGD Ensembl Show fit	similar to swan
chr15_+_62406873 Show fit	0.13	ENSRNOT00000047572	Olfm4 NCBI RGD Ensembl Show fit	olfactomedin 4
chr1_+_99505677 Show fit	0.12	ENSRNOT00000024645	Zfp719 NCBI RGD Ensembl Show fit	zinc finger protein 719
chr1_+_217345545 Show fit	0.12	ENSRNOT00000071741	Shank2 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 2
chr9_+_67234303 Show fit	0.11	ENSRNOT00000050179	Abi2 NCBI RGD Ensembl Show fit	abl-interactor 2

Showing 1 to 10 of 113 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa7_Hoxc8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	GO:0021888	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) facioacoustic ganglion development(GO:1903375)
0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	GO:1901856	negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873)
0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)

Showing 1 to 10 of 11 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	GO:0031209	SCAR complex(GO:0031209)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	GO:0015292	uniporter activity(GO:0015292)
0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)

Showing 1 to 6 of 6 entries

Results for Hoxa7_Hoxc8

Z-value: 0.47

Motif logo

Transcription factors associated with Hoxa7_Hoxc8

Activity-expression correlation:

Activity profile of Hoxa7_Hoxc8 motif

Sorted Z-values of Hoxa7_Hoxc8 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa7_Hoxc8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: