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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa13

Z-value: 0.94

Motif logo

Transcription factors associated with Hoxa13

Gene Symbol Gene ID Gene Info
ENSRNOG00000057061 homeo box A13

Activity profile of Hoxa13 motif

Sorted Z-values of Hoxa13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_27862868 2.92 ENSRNOT00000004877
gamma-aminobutyric acid type A receptor alpha 6 subunit
chr4_+_170149029 0.85 ENSRNOT00000073287
histone H2A.J
chr17_-_61332391 0.63 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr3_-_64554953 0.52 ENSRNOT00000067452
serine/arginine repetitive matrix protein 1-like
chr20_-_5064469 0.52 ENSRNOT00000001120
lymphocyte antigen 6 complex, locus G6D
chr2_+_198359754 0.44 ENSRNOT00000048582
histone cluster 2 H2A family member b
chr10_-_59888198 0.43 ENSRNOT00000093482
ENSRNOT00000049311
ENSRNOT00000093230
aspartoacylase
chr1_-_124803363 0.41 ENSRNOT00000066380
Kruppel-like factor 13
chrX_+_33884499 0.36 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr7_-_136997050 0.36 ENSRNOT00000009143
developing brain homeobox 2
chr4_-_727691 0.35 ENSRNOT00000008497
sonic hedgehog
chr3_+_79613171 0.34 ENSRNOT00000011467
ATP/GTP binding protein-like 2
chr6_-_106971250 0.33 ENSRNOT00000010926
double PHD fingers 3
chr4_+_78263866 0.32 ENSRNOT00000033807
expressed sequence AI854703
chr10_-_40953467 0.31 ENSRNOT00000092189
glycine receptor, alpha 1
chr4_-_179512471 0.30 ENSRNOT00000012588
KRAS proto-oncogene, GTPase
chr19_-_37916813 0.29 ENSRNOT00000026585
lecithin cholesterol acyltransferase
chr2_-_198339130 0.28 ENSRNOT00000028767
bolA family member 1
chr2_-_210116038 0.28 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr7_+_123168811 0.27 ENSRNOT00000007091
cold shock domain containing C2
chr2_-_198360678 0.27 ENSRNOT00000051917
histone cluster 2 H2A family member c
chr5_+_139963002 0.27 ENSRNOT00000048506
collagen type IX alpha 2 chain
chr7_+_38742051 0.26 ENSRNOT00000006070
decorin
chr16_+_54332660 0.26 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr17_-_78561613 0.25 ENSRNOT00000020220
family with sequence similarity 107, member B
chr13_+_36532758 0.25 ENSRNOT00000083007
engrailed 1
chr4_+_66276835 0.25 ENSRNOT00000007544
formation of mitochondrial complex V assembly factor 1
chr4_+_157726941 0.25 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr19_+_25123724 0.24 ENSRNOT00000007407
hypothetical protein LOC686013
chr15_-_23969011 0.23 ENSRNOT00000014821
GTP cyclohydrolase 1
chr4_-_10329241 0.23 ENSRNOT00000017232
fibrinogen-like 2
chr18_+_70970596 0.21 ENSRNOT00000025217
ENSRNOT00000039203
ribosomal protein L17
chr4_-_51199570 0.21 ENSRNOT00000010788
solute carrier family 13 member 1
chr1_-_69835185 0.21 ENSRNOT00000020757
spindle assembly abnormal protein 6 homolog
chr5_-_150167077 0.20 ENSRNOT00000088493
ENSRNOT00000013761
ENSRNOT00000067349
ENSRNOT00000051097
ENSRNOT00000067189
erythrocyte membrane protein band 4.1
chr4_-_170860225 0.20 ENSRNOT00000007577
matrix Gla protein
chr4_-_130659697 0.20 ENSRNOT00000072374
rCG56280-like
chr4_+_155313671 0.20 ENSRNOT00000020812
microfibrillar associated protein 5
chr11_-_87081950 0.20 ENSRNOT00000002574
DiGeorge syndrome critical region gene 6
chr4_+_170766900 0.19 ENSRNOT00000044446
H2A histone family, member J
chr9_-_79545024 0.19 ENSRNOT00000021152
melanoregulin
chr10_-_56558487 0.19 ENSRNOT00000023256
solute carrier family 2 member 4
chr3_+_131351587 0.19 ENSRNOT00000010835
BTB domain containing 3
chr3_+_79713567 0.19 ENSRNOT00000012110
C1q and tumor necrosis factor related protein 4
chr13_-_61070599 0.18 ENSRNOT00000005251
regulator of G-protein signaling 1
chr11_-_46369577 0.18 ENSRNOT00000049859
ENSRNOT00000047817
ENSRNOT00000002220
ENSRNOT00000002223
ENSRNOT00000063864
ENSRNOT00000070871
ENSRNOT00000072140
ABI family member 3 binding protein
chr1_-_93949187 0.17 ENSRNOT00000018956
zinc finger protein 536
chr9_+_98668231 0.17 ENSRNOT00000027528
ankyrin repeat and SOCS box-containing 1
chrX_-_123474154 0.17 ENSRNOT00000092415
ENSRNOT00000092455
similar to hypothetical protein FLJ22965
chr10_+_54155876 0.17 ENSRNOT00000072855
growth arrest specific 7
chr8_+_22458899 0.17 ENSRNOT00000066007
ENSRNOT00000010947
ENSRNOT00000065028
dynamin 2
chr11_+_72705129 0.17 ENSRNOT00000073330
apolipoprotein D
chr2_+_200603426 0.17 ENSRNOT00000072189
zinc finger protein 697-like
chr4_-_82141385 0.17 ENSRNOT00000008447
homeobox A3
chr2_-_205212681 0.17 ENSRNOT00000022575
thyroid stimulating hormone, beta
chr10_+_72272248 0.16 ENSRNOT00000003908
carbonic anhydrase 4
chr1_+_124477164 0.16 ENSRNOT00000048744
high mobility group nucleosome binding domain 5B
chr11_+_80255790 0.16 ENSRNOT00000002522
B-cell CLL/lymphoma 6
chr2_+_200572502 0.16 ENSRNOT00000074666
zinc finger protein 697
chr1_-_67065797 0.16 ENSRNOT00000048152
vomeronasal 1 receptor 46
chrX_-_14890606 0.16 ENSRNOT00000049864
similar to RIKEN cDNA B630019K06
chr2_+_38230757 0.16 ENSRNOT00000048598
similar to 60S ribosomal protein L23a
chr4_+_3959640 0.16 ENSRNOT00000009439
PAX interacting protein 1
chr6_-_78817641 0.16 ENSRNOT00000072117

chr14_+_5928737 0.16 ENSRNOT00000071877
ENSRNOT00000040985
ENSRNOT00000074889
macrophage activation 2 like
chr15_-_37831031 0.15 ENSRNOT00000091562
eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr12_-_2438817 0.15 ENSRNOT00000037059
C-C motif chemokine ligand 25
chr1_-_222242644 0.15 ENSRNOT00000050891
vascular endothelial growth factor B
chr17_+_9289189 0.15 ENSRNOT00000015632
H2A histone family, member Y
chr2_-_208215187 0.15 ENSRNOT00000047836
RAP1A, member of RAS oncogene family
chr20_+_26534535 0.14 ENSRNOT00000000423
transmembrane protein 167B
chr4_-_180234804 0.14 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr5_-_150949931 0.14 ENSRNOT00000067905
sphingomyelin phosphodiesterase, acid-like 3B
chr14_-_20920286 0.14 ENSRNOT00000004391
solute carrier family 4 member 4
chr4_+_180062799 0.14 ENSRNOT00000021623
Ras association domain family member 8
chr7_-_74328603 0.14 ENSRNOT00000079159
ATM interactor
chr15_-_76789298 0.14 ENSRNOT00000077853

chr17_-_80860195 0.14 ENSRNOT00000038651
tRNA aspartic acid methyltransferase 1
chr2_+_8732932 0.14 ENSRNOT00000072849
arrestin domain containing 3
chr3_+_114772603 0.14 ENSRNOT00000073569
hypothetical LOC302884
chr10_+_46314375 0.14 ENSRNOT00000088300
mediator complex subunit 9
chr15_+_61673560 0.13 ENSRNOT00000093661
mitochondrial translation release factor 1
chr3_+_145764932 0.13 ENSRNOT00000075257

chrX_+_6273733 0.13 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr4_+_153217782 0.13 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chr11_+_36634662 0.13 ENSRNOT00000050178
Beta-1,3-galactosyltransferase 5
chr19_+_52515022 0.13 ENSRNOT00000022091
kelch-like family member 36
chr9_-_9702306 0.13 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr20_+_248410 0.13 ENSRNOT00000049573
trimethyllysine hydroxylase, epsilon
chr16_+_50152008 0.13 ENSRNOT00000019237
kallikrein B1
chr1_+_251633199 0.12 ENSRNOT00000084785

chr11_-_59110562 0.12 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chr1_-_89369960 0.12 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr20_+_1749716 0.12 ENSRNOT00000048856
olfactory receptor 1735
chr16_-_20860767 0.12 ENSRNOT00000027275
ENSRNOT00000092417
growth differentiation factor 1
ceramide synthase 1
chr5_-_146973932 0.12 ENSRNOT00000007761
zinc finger protein 362
chr3_-_8766433 0.12 ENSRNOT00000021865
kynurenine aminotransferase 1
chrX_+_71528988 0.12 ENSRNOT00000075963
O-linked N-acetylglucosamine (GlcNAc) transferase
chr7_+_79638046 0.12 ENSRNOT00000029419
zinc finger protein, multitype 2
chr5_-_174921 0.12 ENSRNOT00000056239
TIMELESS interacting protein like 1
chr8_+_117906014 0.12 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chr8_+_99568958 0.12 ENSRNOT00000073400
phospholipid scramblase family, member 5
chr3_+_149624712 0.12 ENSRNOT00000018581
BPI fold containing family A, member 1
chr4_+_165732643 0.12 ENSRNOT00000034403
hypothetical protein LOC690326
chr8_+_118066988 0.11 ENSRNOT00000056161
microtubule-associated protein 4
chr5_-_113880911 0.11 ENSRNOT00000029441
equatorin
chr2_+_188583664 0.11 ENSRNOT00000045477
dolichyl-phosphate mannosyltransferase subunit 3
chr3_+_61658245 0.11 ENSRNOT00000033511
homeo box D3
chr17_-_42127678 0.11 ENSRNOT00000024196
glycosylphosphatidylinositol specific phospholipase D1
chr1_+_204959174 0.11 ENSRNOT00000023257
zinc finger RANBP2-type containing 1
chr4_-_176679815 0.11 ENSRNOT00000090122
glycogen synthase 2
chr12_-_13668515 0.11 ENSRNOT00000086847
fascin actin-bundling protein 1
chr3_+_160935709 0.11 ENSRNOT00000019688
dysbindin domain containing 2
chr1_+_279798187 0.11 ENSRNOT00000024065
pancreatic lipase
chr20_+_6877091 0.11 ENSRNOT00000093654
similar to GI:13385412-like protein splice form I
chr5_-_139853247 0.11 ENSRNOT00000056644
exonuclease 5
chr18_+_3565166 0.11 ENSRNOT00000039377
RIO kinase 3
chrX_-_73766885 0.11 ENSRNOT00000091325
ring finger protein, LIM domain interacting
chr10_+_58784660 0.11 ENSRNOT00000019925
uncharacterized LOC100912483
chr6_+_55812747 0.11 ENSRNOT00000008106
sclerostin domain containing 1
chr12_+_51878153 0.11 ENSRNOT00000056798
HscB mitochondrial iron-sulfur cluster co-chaperone
chr2_-_96509424 0.10 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr7_-_70319346 0.10 ENSRNOT00000071543
Ts translation elongation factor, mitochondrial
chr6_+_56846789 0.10 ENSRNOT00000032108
alkylglycerol monooxygenase
chr15_-_39705208 0.10 ENSRNOT00000015412
PHD finger protein 11
chr7_-_15856676 0.10 ENSRNOT00000086553

chr17_-_29895386 0.10 ENSRNOT00000048757
chromodomain Y-like
chr10_-_97756521 0.10 ENSRNOT00000045902
solute carrier family 16, member 6
chr6_+_137889261 0.10 ENSRNOT00000034995
testis expressed 22
chr1_+_207508414 0.10 ENSRNOT00000054896
neuropeptide S
chr13_+_90533365 0.10 ENSRNOT00000082469
DDB1 and CUL4 associated factor 8
chrX_+_112769645 0.10 ENSRNOT00000064478
collagen type IV alpha 5 chain
chr2_+_196277978 0.10 ENSRNOT00000028625
vacuolar protein sorting 72 homolog
chr5_+_144054452 0.10 ENSRNOT00000011565
mitochondrial ribosomal protein S15
chr5_-_139748489 0.09 ENSRNOT00000078741
nuclear transcription factor Y subunit gamma
chr17_-_44643362 0.09 ENSRNOT00000091041
zinc finger protein 184
chr3_-_64364101 0.09 ENSRNOT00000089065
zinc finger protein 385B
chr1_+_197813963 0.09 ENSRNOT00000045531
ribosomal protein L36-like
chr15_+_17775692 0.09 ENSRNOT00000061169
similar to RIKEN cDNA 4933406L09
chr11_-_4397361 0.09 ENSRNOT00000046370
cell adhesion molecule 2
chr8_+_91820783 0.09 ENSRNOT00000043351
similar to mitochondrial ribosomal protein L41
chr8_-_96985558 0.09 ENSRNOT00000018553
similar to UPF0258 protein KIAA1024
chr2_-_148807813 0.09 ENSRNOT00000047649

chr13_-_93677377 0.09 ENSRNOT00000004917
fumarate hydratase
chr4_-_6978073 0.09 ENSRNOT00000045311
negative regulator of ubiquitin-like proteins 1
chr10_-_47546345 0.09 ENSRNOT00000077461
aldehyde dehydrogenase 3 family, member A2
chr20_+_2088533 0.09 ENSRNOT00000001012
ENSRNOT00000079021
zinc ribbon domain containing 1
chr9_+_52023295 0.09 ENSRNOT00000004956
collagen type III alpha 1 chain
chr9_+_51298426 0.09 ENSRNOT00000065212
GULP, engulfment adaptor PTB domain containing 1
chr3_+_151126591 0.09 ENSRNOT00000025859
myosin heavy chain 7B
chr5_+_50381244 0.09 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chrX_+_90588124 0.08 ENSRNOT00000045685
TGFB-induced factor homeobox 2-like, X-linked 2
chrX_-_153080915 0.08 ENSRNOT00000091365
X-linked lymphocyte-regulated 4A
chr3_+_108944141 0.08 ENSRNOT00000034950
family with sequence similarity 98, member B
chr4_+_64088900 0.08 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr10_-_62184874 0.08 ENSRNOT00000004229
replication protein A1
chr1_-_89483988 0.08 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr18_+_79406381 0.08 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr18_+_29951094 0.08 ENSRNOT00000027402
protocadherin alpha-1-like
chr5_+_5279296 0.08 ENSRNOT00000045373
translocation associated membrane protein 1
chr4_-_157486844 0.08 ENSRNOT00000038281
ENSRNOT00000022874
COP9 signalosome subunit 7A
chr7_+_35309265 0.08 ENSRNOT00000080291
transmembrane and coiled-coil domain family 3
chr6_+_72124417 0.08 ENSRNOT00000040548
sec1 family domain containing 1
chr17_-_23792353 0.08 ENSRNOT00000019089
TBC1 domain family, member 7
chr10_+_80953006 0.08 ENSRNOT00000035567
heterogeneous nuclear ribonucleoprotein A3
chr2_+_237755673 0.08 ENSRNOT00000083937
TBC1 domain containing kinase
chr11_+_7422272 0.08 ENSRNOT00000075964
1,4-alpha-glucan branching enzyme 1
chr9_+_94324793 0.08 ENSRNOT00000092493
eukaryotic translation initiation factor 4E family member 2
chr11_+_68198709 0.08 ENSRNOT00000003048
disrupted in renal carcinoma 2
chr2_-_88553086 0.08 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr9_+_73529612 0.07 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chr4_+_61850348 0.07 ENSRNOT00000013423
aldo-keto reductase family 1, member B7
chr19_-_43911057 0.07 ENSRNOT00000026017
chymotrypsinogen B1
chr13_+_53283855 0.07 ENSRNOT00000043590
similar to ribosomal protein L31
chr2_+_30685840 0.07 ENSRNOT00000031385
coiled-coil domain containing 125
chr2_+_68821004 0.07 ENSRNOT00000083713
epidermal growth factor
chr3_-_40477754 0.07 ENSRNOT00000091168

chr7_-_73883812 0.07 ENSRNOT00000065722
serine/threonine kinase 3
chr3_-_154490851 0.07 ENSRNOT00000017213
TELO2 interacting protein 1
chr9_-_18371856 0.07 ENSRNOT00000027293
SPT3 homolog, SAGA and STAGA complex component
chrX_-_1718637 0.07 ENSRNOT00000064309
cyclin-dependent kinase 16
chr11_+_85508300 0.07 ENSRNOT00000038646

chr11_+_46184871 0.07 ENSRNOT00000048417
Trk-fused gene
chr18_+_35489274 0.07 ENSRNOT00000073952
ENSRNOT00000076060
decapping mRNA 2
chr3_-_151224123 0.07 ENSRNOT00000026091
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr7_-_11266630 0.07 ENSRNOT00000027926
cactin, spliceosome C complex subunit
chr1_+_218003018 0.07 ENSRNOT00000028343
fibroblast growth factor 3
chr10_+_764421 0.07 ENSRNOT00000084608
ENSRNOT00000087567
myosin heavy chain 11
chr9_-_88534710 0.07 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr4_+_162493908 0.07 ENSRNOT00000072064
C-type lectin domain family 2, member D
chr14_+_82769642 0.07 ENSRNOT00000065393
C-terminal binding protein 1
chr2_-_45518502 0.07 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr1_-_266862842 0.07 ENSRNOT00000027496
up-regulated during skeletal muscle growth protein 5
chr1_-_227932603 0.07 ENSRNOT00000033795
membrane spanning 4-domains A6A
chr2_+_23770721 0.07 ENSRNOT00000014795
lipoma HMGIC fusion partner-like 2
chr15_+_48030973 0.07 ENSRNOT00000085487
ENSRNOT00000029757
kinesin family member 13B
chr16_-_20873344 0.07 ENSRNOT00000027381
coatomer protein complex, subunit epsilon
chr14_+_84211600 0.07 ENSRNOT00000005996
pescadillo ribosomal biogenesis factor 1
chr19_+_38643108 0.06 ENSRNOT00000087392
ribosomal protein L28-like
chr7_-_11406771 0.06 ENSRNOT00000047450
eukaryotic translation elongation factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0065001 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) specification of axis polarity(GO:0065001) negative regulation of cholesterol efflux(GO:0090370) negative regulation of dopaminergic neuron differentiation(GO:1904339) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.1 GO:0071282 cellular response to iron(II) ion(GO:0071282)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970) positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.0 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.3 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) high-density lipoprotein particle assembly(GO:0034380)
0.0 0.1 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.6 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.0 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 1.7 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671) cellular response to fluoride(GO:1902618)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.0 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0001842 neural fold formation(GO:0001842)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.0 GO:1903422 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.0 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:0044332 STAT protein import into nucleus(GO:0007262) Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.2 GO:0070821 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.3 GO:0030977 taurine binding(GO:0030977)
0.1 0.3 GO:0019002 GMP binding(GO:0019002)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.0 GO:0031997 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening