ISMARA results: Hoxa11

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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa11_Hoxc12

Z-value: 0.38

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Transcription factors associated with Hoxa11_Hoxc12

Gene Symbol	Gene ID	Gene Info
Hoxa11 NCBI RGD Ensembl	ENSRNOG00000059870	homeobox A11
Hoxa11 NCBI RGD Ensembl	ENSRNOG00000053884	homeobox A11
Hoxc12 NCBI RGD Ensembl	ENSRNOG00000016116	homeo box C12

Activity profile of Hoxa11_Hoxc12 motif

Sorted Z-values of Hoxa11_Hoxc12 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_+_4362717 Show fit	0.28	ENSRNOT00000002887	Barhl2 NCBI RGD Ensembl Show fit	BarH-like homeobox 2
chr4_-_82173207 Show fit	0.22	ENSRNOT00000074167	Hoxa5 NCBI RGD Ensembl Show fit	homeo box A5
chr7_-_13751271 Show fit	0.20	ENSRNOT00000009931	Slc1a6 NCBI RGD Ensembl Show fit	solute carrier family 1 member 6
chr10_+_84152152 Show fit	0.19	ENSRNOT00000010724	Hoxb5 NCBI RGD Ensembl Show fit	homeo box B5
chr5_+_152533349 Show fit	0.13	ENSRNOT00000067524	Trim63 NCBI RGD Ensembl Show fit	tripartite motif containing 63
chr5_-_156734541 Show fit	0.10	ENSRNOT00000021036	LOC100909857 NCBI RGD Ensembl Show fit	cytidine deaminase-like
chr3_-_64554953 Show fit	0.10	ENSRNOT00000067452	LOC102553814 NCBI RGD Ensembl Show fit	serine/arginine repetitive matrix protein 1-like
chr15_-_37831031 Show fit	0.09	ENSRNOT00000091562	Eef1akmt1 NCBI RGD Ensembl Show fit	eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr1_+_154606490 Show fit	0.08	ENSRNOT00000024095	Ccdc89 NCBI RGD Ensembl Show fit	coiled-coil domain containing 89
chr4_+_66276835 Show fit	0.08	ENSRNOT00000007544	Fmc1 NCBI RGD Ensembl Show fit	formation of mitochondrial complex V assembly factor 1

Showing 1 to 10 of 134 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa11_Hoxc12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.0	GO:0033128	negative regulation of histone phosphorylation(GO:0033128) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0	0.0	GO:1990737	negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0	0.0	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.0	0.0	GO:0071250	cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033)

Showing 1 to 10 of 11 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:1990590	Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	GO:0031432	titin binding(GO:0031432)
0.1	GO:0001155	TFIIIA-class transcription factor binding(GO:0001155)

Showing 1 to 6 of 6 entries

Results for Hoxa11_Hoxc12

Z-value: 0.38

Motif logo

Transcription factors associated with Hoxa11_Hoxc12

Activity profile of Hoxa11_Hoxc12 motif

Sorted Z-values of Hoxa11_Hoxc12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa11_Hoxc12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: