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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa10

Z-value: 0.32

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Transcription factors associated with Hoxa10

Gene Symbol Gene ID Gene Info
ENSRNOG00000057650 homeobox A10

Activity profile of Hoxa10 motif

Sorted Z-values of Hoxa10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_64224861 0.16 ENSRNOT00000093159
ENSRNOT00000093664
patatin-like phospholipase domain containing 8
chr10_+_14136883 0.15 ENSRNOT00000082295

chr13_-_83425641 0.14 ENSRNOT00000063870
T-box 19
chr2_+_231941794 0.11 ENSRNOT00000091475

chr8_+_130366775 0.11 ENSRNOT00000071152
natural killer cell triggering receptor
chr6_+_106052212 0.10 ENSRNOT00000010626
signal-induced proliferation-associated 1 like 1
chr9_-_65736852 0.10 ENSRNOT00000087458
trafficking kinesin protein 2
chr18_-_32670665 0.10 ENSRNOT00000019409
nuclear receptor subfamily 3, group C, member 1
chr7_-_101138860 0.10 ENSRNOT00000077137

chr8_-_94920441 0.10 ENSRNOT00000014165
centrosomal protein 162
chr3_-_119405453 0.09 ENSRNOT00000090355
signal peptide peptidase-like 2A
chr3_-_146396299 0.09 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr18_+_30904498 0.09 ENSRNOT00000026969
protocadherin gamma subfamily A, 11
chr10_-_27179254 0.09 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr4_-_125958112 0.09 ENSRNOT00000071315
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr9_-_65737538 0.09 ENSRNOT00000014939
trafficking kinesin protein 2
chr1_-_246010594 0.09 ENSRNOT00000023762
regulatory factor X3
chr2_+_242882306 0.08 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr7_+_133457255 0.08 ENSRNOT00000080621
contactin 1
chr15_-_76789298 0.08 ENSRNOT00000077853

chr2_-_40386669 0.08 ENSRNOT00000014074
ELOVL fatty acid elongase 7
chr14_-_82171480 0.07 ENSRNOT00000021952
nuclear receptor binding SET domain protein 2
chr16_-_9658484 0.07 ENSRNOT00000065216
mitogen-activated protein kinase 8
chr14_-_28856214 0.07 ENSRNOT00000044659
adhesion G protein-coupled receptor L3
chr13_+_98231326 0.07 ENSRNOT00000003837
CDC42 binding protein kinase alpha
chr3_+_113918629 0.06 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr3_-_66279155 0.06 ENSRNOT00000079887
ceramide kinase-like
chr1_-_90151405 0.06 ENSRNOT00000028688
similar to RIKEN cDNA 4931406P16
chr12_+_38368693 0.06 ENSRNOT00000083261
CAP-GLY domain containing linker protein 1
chr19_-_22194740 0.06 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr17_-_86657473 0.06 ENSRNOT00000078827

chr9_-_43454078 0.06 ENSRNOT00000023550
transmembrane protein 131
chr10_-_104482838 0.05 ENSRNOT00000007246
RecQ like helicase 5
chr18_+_30496318 0.05 ENSRNOT00000027179
protocadherin beta 11
chr18_-_77317969 0.05 ENSRNOT00000090369
nuclear factor of activated T-cells 1
chr2_+_123597340 0.05 ENSRNOT00000058552
similar to RIKEN cDNA D630029K19
chr3_+_112390106 0.05 ENSRNOT00000081197
similar to Centrosomal protein of 27 kDa (Cep27 protein)
chr16_+_54319377 0.05 ENSRNOT00000090266
microtubule associated tumor suppressor 1
chr13_-_51784639 0.05 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr7_-_104801045 0.05 ENSRNOT00000079524
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr8_+_122197027 0.05 ENSRNOT00000013050
upstream binding protein 1 (LBP-1a)
chr17_+_81922329 0.04 ENSRNOT00000031542
calcium voltage-gated channel auxiliary subunit beta 2
chr2_+_4989295 0.04 ENSRNOT00000041541
family with sequence similarity 172, member A
chr9_-_52238564 0.04 ENSRNOT00000005073
collagen type V alpha 2 chain
chr5_+_116420690 0.04 ENSRNOT00000087089
nuclear factor I/A
chr11_+_62584959 0.04 ENSRNOT00000071065
GRAM domain containing 1C
chr14_-_21128505 0.04 ENSRNOT00000004776
RUN and FYVE domain containing 3
chr3_-_119405300 0.04 ENSRNOT00000015568
signal peptide peptidase-like 2A
chr15_-_13228607 0.04 ENSRNOT00000042010
ENSRNOT00000088214
protein tyrosine phosphatase, receptor type, G
chr14_+_39964588 0.04 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr3_-_71798531 0.04 ENSRNOT00000088170
calcitonin receptor like receptor
chr1_-_250626844 0.04 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr2_+_231884337 0.04 ENSRNOT00000014695
zinc finger, GRF-type containing 1
chr3_-_25212049 0.04 ENSRNOT00000040023
LDL receptor related protein 1B
chr5_+_147257678 0.04 ENSRNOT00000066268
ring finger protein 19B
chr3_-_176197753 0.03 ENSRNOT00000013189
death inducer-obliterator 1
chr4_+_160020472 0.03 ENSRNOT00000078802
poly (ADP-ribose) polymerase family, member 11
chr8_-_58253688 0.03 ENSRNOT00000010956
cullin 5
chr17_+_26478315 0.03 ENSRNOT00000021669
solute carrier family 35 member B3
chr7_+_74350479 0.03 ENSRNOT00000089034

chr5_-_58198782 0.03 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr7_-_122329443 0.03 ENSRNOT00000032232
megakaryoblastic leukemia (translocation) 1
chr16_-_2602103 0.03 ENSRNOT00000018413
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
chr11_-_37253776 0.03 ENSRNOT00000002215
DS cell adhesion molecule
chr7_+_132378273 0.03 ENSRNOT00000010990
hypothetical protein LOC690142
chr13_-_82295123 0.03 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr2_-_147819335 0.03 ENSRNOT00000057909
ankyrin repeat and ubiquitin domain containing 1
chr5_-_128839433 0.03 ENSRNOT00000065280
oxysterol binding protein-like 9
chr17_-_18421861 0.03 ENSRNOT00000060500
ENSRNOT00000036560
family with sequence similarity 8, member A1
chr19_+_56803382 0.03 ENSRNOT00000036042
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr15_+_39644851 0.03 ENSRNOT00000081373
RCC1 and BTB domain containing protein 1
chr14_+_42007312 0.03 ENSRNOT00000063985
ATPase phospholipid transporting 8A1
chr16_-_48692476 0.03 ENSRNOT00000013118
interferon regulatory factor 2
chr1_+_266844480 0.03 ENSRNOT00000027482
TATA-box binding protein associated factor 5
chr3_+_60026747 0.03 ENSRNOT00000081881
secernin 3
chr4_+_91373942 0.02 ENSRNOT00000043827
coiled-coil serine-rich protein 1
chr13_+_90260783 0.02 ENSRNOT00000050547
CD84 molecule
chr2_+_66940057 0.02 ENSRNOT00000043050
cadherin 9
chr8_+_64610952 0.02 ENSRNOT00000015963
myosin IXA
chr1_-_197801634 0.02 ENSRNOT00000090200
nuclear factor of activated T-cells 2 interacting protein
chr5_-_113880911 0.02 ENSRNOT00000029441
equatorin
chr3_+_158997834 0.02 ENSRNOT00000000211
von Willebrand factor A domain-containing protein 5A
chrX_+_84064427 0.02 ENSRNOT00000046364
zinc finger protein 711
chr3_-_64543100 0.02 ENSRNOT00000025803
zinc finger protein 385B
chr13_-_74923402 0.02 ENSRNOT00000033324
RAS protein activator like 2
chr1_+_256226179 0.02 ENSRNOT00000054748
exocyst complex component 6
chr16_-_7412150 0.02 ENSRNOT00000047252
similar to ribosomal protein S24
chr16_+_71242470 0.02 ENSRNOT00000030489
leucine zipper and EF-hand containing transmembrane protein 2
chr10_-_91661558 0.02 ENSRNOT00000043156

chr8_+_96551245 0.02 ENSRNOT00000039850
BCL2-related protein A1
chr20_+_3167079 0.02 ENSRNOT00000001035
RT1 class Ib, locus N3
chr8_+_31497639 0.02 ENSRNOT00000020041
sorting nexin 19
chr3_-_153321352 0.02 ENSRNOT00000064824
RB transcriptional corepressor like 1
chr3_-_60166013 0.02 ENSRNOT00000024922
WAS/WASL interacting protein family, member 1
chr3_-_150960030 0.02 ENSRNOT00000024714
nuclear receptor coactivator 6
chr19_-_11669578 0.02 ENSRNOT00000026373
G protein subunit alpha o1
chr14_-_45863877 0.02 ENSRNOT00000002977
phosphoglucomutase 2
chrX_+_88298266 0.02 ENSRNOT00000041508

chr2_+_196139755 0.02 ENSRNOT00000040501
phosphatidylinositol 4-kinase beta
chr3_+_47995959 0.01 ENSRNOT00000082775
solute carrier family 4 member 10
chr2_-_43067956 0.01 ENSRNOT00000090616
GC-rich promoter binding protein 1
chrX_+_77076106 0.01 ENSRNOT00000091527
ENSRNOT00000089381
ATPase copper transporting alpha
chr7_-_70319346 0.01 ENSRNOT00000071543
Ts translation elongation factor, mitochondrial
chr8_+_42443442 0.01 ENSRNOT00000015986
von Willebrand factor A domain containing 5A
chr1_-_197821936 0.01 ENSRNOT00000055027
CD19 molecule
chr2_-_53313884 0.01 ENSRNOT00000046951
growth hormone receptor
chr4_+_182483194 0.01 ENSRNOT00000002528
fatty acyl CoA reductase 2
chr14_-_62595854 0.01 ENSRNOT00000003024
Yip1 domain family, member 7
chr6_+_73358112 0.01 ENSRNOT00000041373
Rho GTPase activating protein 5
chr4_+_34237762 0.01 ENSRNOT00000084163
meiosis regulator for oocyte development
chr14_+_83889089 0.01 ENSRNOT00000078980
MORC family CW-type zinc finger 2
chr8_-_47094352 0.01 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chrX_+_44907521 0.01 ENSRNOT00000004901
transducin (beta)-like 1 X-linked
chr5_+_135354700 0.01 ENSRNOT00000021850
intracisternal A particle-promoted polypeptide
chr13_-_84759098 0.01 ENSRNOT00000058683
similar to flavin containing monooxygenase 5
chr2_+_248398917 0.01 ENSRNOT00000045855
guanylate binding protein 1
chr20_+_3146856 0.01 ENSRNOT00000050159
RT1 class Ib, locus N2
chr3_+_151335292 0.01 ENSRNOT00000073642
matrix metallopeptidase 24
chr7_-_15852930 0.01 ENSRNOT00000009270
similar to zinc finger protein 101
chr13_+_110372164 0.01 ENSRNOT00000049634
similar to ribosomal protein L37
chr12_+_2140203 0.01 ENSRNOT00000084906
calmodulin regulated spectrin-associated protein family, member 3
chr4_+_162493908 0.01 ENSRNOT00000072064
C-type lectin domain family 2, member D
chr6_+_1516158 0.01 ENSRNOT00000062031
uncharacterized LOC103692531
chr18_-_72649915 0.01 ENSRNOT00000072205

chr16_+_54332660 0.01 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr11_+_85508300 0.01 ENSRNOT00000038646

chr4_-_176909075 0.01 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr3_-_13896838 0.01 ENSRNOT00000025399
F-box and WD repeat domain containing 2
chr3_-_102151489 0.00 ENSRNOT00000006349
anoctamin 3
chr13_+_79269973 0.00 ENSRNOT00000003969
tumor necrosis factor superfamily member 4
chr1_-_7443863 0.00 ENSRNOT00000088558
phosphatase and actin regulator 2
chr7_-_101138373 0.00 ENSRNOT00000043257
Ab1-152
chr9_+_27408333 0.00 ENSRNOT00000088416
glutathione S-transferase alpha 3
chr9_+_113534326 0.00 ENSRNOT00000066793
protein phosphatase 4, regulatory subunit 1
chr8_-_32431987 0.00 ENSRNOT00000048460
similar to 60S ribosomal protein L32
chr6_+_55465782 0.00 ENSRNOT00000006682
anterior gradient 2, protein disulphide isomerase family member
chr17_-_15566332 0.00 ENSRNOT00000093743
extracellular matrix protein 2
chr1_-_134871167 0.00 ENSRNOT00000076300
chromodomain helicase DNA binding protein 2
chr5_-_73986373 0.00 ENSRNOT00000064043
ENSRNOT00000032299
transmembrane protein 245
chr19_+_39126589 0.00 ENSRNOT00000027561
syntrophin, beta 2
chr18_-_27452420 0.00 ENSRNOT00000037888
cell division cycle 23
chr10_-_67401836 0.00 ENSRNOT00000073071
cytokine receptor-like factor 3
chr9_-_88534710 0.00 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr1_+_164705604 0.00 ENSRNOT00000051450
ENSRNOT00000071384
olfactory receptor 36
chr14_+_21041621 0.00 ENSRNOT00000086571
G-rich RNA sequence binding factor 1
chr1_+_167944448 0.00 ENSRNOT00000087667
olfactory receptor 56
chrX_-_37705263 0.00 ENSRNOT00000043666
mitogen-activated protein kinase kinase kinase 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)