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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hnf4a
Z-value: 0.40
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Transcription factors associated with Hnf4a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hnf4a | rn6_v1_chr3_+_159902441_159902524 | -0.67 | 2.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_123638702 Show fit | 0.34 |
ENSRNOT00000082473
ENSRNOT00000044470 ENSRNOT00000092017 |
cytochrome P450, family 2, subfamily d, polypeptide 1 |
|
| chr4_+_88832178 Show fit | 0.12 |
ENSRNOT00000088983
|
ATP-binding cassette, subfamily G (WHITE), member 2 |
|
| chr10_+_11373346 Show fit | 0.10 |
ENSRNOT00000044624
|
coronin-7-like |
|
| chr2_-_219741886 Show fit | 0.10 |
ENSRNOT00000085122
|
solute carrier family 35 member A3 |
|
| chr2_-_207300854 Show fit | 0.09 |
ENSRNOT00000018061
|
Mov10 RISC complex RNA helicase |
|
| chr6_+_79254339 Show fit | 0.09 |
ENSRNOT00000073970
|
somatostatin receptor 1 |
|
| chr1_+_220428481 Show fit | 0.08 |
ENSRNOT00000027335
|
ras and Rab interactor 1 |
|
| chr11_+_87058616 Show fit | 0.08 |
ENSRNOT00000002576
ENSRNOT00000082855 |
proline dehydrogenase 1 |
|
| chr4_+_100218661 Show fit | 0.08 |
ENSRNOT00000079415
|
transmembrane protein 150A |
|
| chr11_-_70833577 Show fit | 0.08 |
ENSRNOT00000002428
|
oxysterol binding protein-like 11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hnf4a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.0 | 0.1 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.0 | 0.1 | GO:1904612 | glucuronoside metabolic process(GO:0019389) response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612) |
| 0.0 | 0.1 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 0.0 | 0.1 | GO:0072237 | metanephric proximal tubule development(GO:0072237) |
| 0.0 | 0.1 | GO:2001106 | fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 0.1 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.0 | 0.1 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.0 | 0.1 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 0.1 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.0 | 0.1 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.0 | 0.1 | GO:0015168 | polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168) |
| 0.0 | 0.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.0 | 0.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.0 | 0.1 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.1 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.0 | 0.1 | GO:0042731 | PH domain binding(GO:0042731) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |