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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hnf1a
Z-value: 0.48
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Transcription factors associated with Hnf1a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hnf1a | rn6_v1_chr12_+_47407811_47407811 | 0.12 | 8.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_32153794 Show fit | 0.32 |
ENSRNOT00000005348
|
transmembrane protein 27 |
|
| chr14_-_19132208 Show fit | 0.30 |
ENSRNOT00000060535
|
afamin |
|
| chr14_+_84231639 Show fit | 0.14 |
ENSRNOT00000066362
|
galactose-3-O-sulfotransferase 1 |
|
| chr19_-_39267928 Show fit | 0.14 |
ENSRNOT00000027686
|
transmembrane p24 trafficking protein 6 |
|
| chr8_+_22856539 Show fit | 0.13 |
ENSRNOT00000015381
|
angiopoietin-like 8 |
|
| chr4_+_66670618 Show fit | 0.11 |
ENSRNOT00000010796
|
thromboxane A synthase 1 |
|
| chr6_-_127534247 Show fit | 0.11 |
ENSRNOT00000012500
|
serpin family A member 6 |
|
| chr5_-_68059933 Show fit | 0.08 |
ENSRNOT00000088716
|
phospholipid phosphatase related 1 |
|
| chr13_-_50549981 Show fit | 0.08 |
ENSRNOT00000003918
ENSRNOT00000080486 |
golgi transport 1A |
|
| chr3_-_54625414 Show fit | 0.08 |
ENSRNOT00000037133
|
serine threonine kinase 39 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hnf1a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.1 | GO:1902569 | regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569) |
| 0.0 | 0.1 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.0 | 0.1 | GO:0034441 | plasma lipoprotein particle oxidation(GO:0034441) negative regulation of lipoprotein oxidation(GO:0034443) |
| 0.0 | 0.1 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 0.0 | 0.1 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.0 | 0.1 | GO:1904975 | response to bleomycin(GO:1904975) |
| 0.0 | 0.1 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 0.1 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.0 | 0.1 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.0 | GO:0043159 | acrosomal matrix(GO:0043159) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.0 | 0.1 | GO:0031714 | C5a anaphylatoxin chemotactic receptor binding(GO:0031714) |
| 0.0 | 0.1 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.0 | 0.1 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.1 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.0 | 0.1 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.0 | 0.1 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.0 | 0.0 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.0 | 0.0 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |