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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hmx2

Z-value: 0.12

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Transcription factors associated with Hmx2

Gene Symbol Gene ID Gene Info
ENSRNOG00000020638 H6 family homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmx2rn6_v1_chr1_+_203515609_203515609-0.711.7e-01Click!

Activity profile of Hmx2 motif

Sorted Z-values of Hmx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_27603307 0.07 ENSRNOT00000074702

chr5_-_17061837 0.04 ENSRNOT00000011892
proenkephalin
chr19_-_21970103 0.04 ENSRNOT00000074210

chr5_-_17061361 0.04 ENSRNOT00000089318
proenkephalin
chr6_+_8886591 0.03 ENSRNOT00000091510
ENSRNOT00000089174
SIX homeobox 3
chr15_-_34198921 0.03 ENSRNOT00000024991
neural retina leucine zipper
chrX_+_77143892 0.03 ENSRNOT00000085227
ATPase copper transporting alpha
chr4_-_178168690 0.03 ENSRNOT00000020729
SRY box 5
chr3_-_937102 0.03 ENSRNOT00000007471
histamine N-methyltransferase
chr11_-_29710849 0.03 ENSRNOT00000029345
keratin associated protein 11-1
chr3_-_123698072 0.03 ENSRNOT00000077819
similar to RIKEN cDNA 1700037H04
chr6_+_106153045 0.02 ENSRNOT00000092065
signal-induced proliferation-associated 1 like 1
chrX_+_115208863 0.02 ENSRNOT00000072094

chr15_+_41643541 0.02 ENSRNOT00000019646
ADP-ribosylation factor like GTPase 11
chr1_+_66898946 0.02 ENSRNOT00000074063
zinc finger protein 551
chr10_+_3227160 0.02 ENSRNOT00000088075
N-terminal asparagine amidase
chr4_+_2053712 0.02 ENSRNOT00000045086
ring finger protein 32
chr4_-_171176581 0.02 ENSRNOT00000030850
RAS-like, estrogen-regulated, growth-inhibitor
chr10_-_103619083 0.02 ENSRNOT00000029092
Cd300e molecule
chr5_-_78324278 0.02 ENSRNOT00000082642
ENSRNOT00000048904
WD repeat domain 31
chr19_-_55284663 0.02 ENSRNOT00000018387
snail family transcriptional repressor 3
chr2_-_35104963 0.02 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr12_-_19592000 0.02 ENSRNOT00000001855
galactose-3-O-sulfotransferase 4
chr1_+_252409268 0.01 ENSRNOT00000026219
lipase, family member M
chr10_-_10767389 0.01 ENSRNOT00000066754
small integral membrane protein 22
chr1_-_52495582 0.01 ENSRNOT00000067142
phosphodiesterase 10A
chr20_+_42966140 0.01 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr3_+_148327965 0.01 ENSRNOT00000010851
ENSRNOT00000088481
TPX2, microtubule nucleation factor
chr3_+_44025300 0.01 ENSRNOT00000006319
polypeptide N-acetylgalactosaminyltransferase 5
chr15_-_60752106 0.01 ENSRNOT00000058148
A-kinase anchoring protein 11
chr17_+_57031766 0.01 ENSRNOT00000092187
ENSRNOT00000068545
cAMP responsive element modulator
chr4_-_154044493 0.01 ENSRNOT00000076318
IQ motif and Sec7 domain 3
chr4_+_22859622 0.01 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr2_-_138833933 0.01 ENSRNOT00000013343
protocadherin 18
chr15_-_19575914 0.01 ENSRNOT00000043897

chr5_+_57657909 0.01 ENSRNOT00000073017
similar to ribosomal protein S13
chr2_+_143895982 0.01 ENSRNOT00000080026
SPT20 homolog, SAGA complex component
chr14_+_37130743 0.01 ENSRNOT00000031756
leucine rich repeat containing 66
chr3_-_165537940 0.01 ENSRNOT00000071119
ENSRNOT00000070964
spalt-like transcription factor 4
chr2_-_38208719 0.01 ENSRNOT00000019189
kinesin family member 2A
chr11_-_14304603 0.01 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr2_-_189333015 0.01 ENSRNOT00000076424
ENSRNOT00000076952
HCLS1 associated protein X-1
chr5_+_163773509 0.01 ENSRNOT00000072167
60S ribosomal protein L9 pseudogene
chr14_-_34218961 0.01 ENSRNOT00000072588
similar to Exocyst complex component 1 (Exocyst complex component Sec3)
chr4_-_22425381 0.01 ENSRNOT00000011166
ENSRNOT00000037712
ATP binding cassette subfamily B member 1A
chr1_-_16687817 0.01 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr3_-_90751055 0.01 ENSRNOT00000040741
LRRGT00091
chr12_+_10254951 0.01 ENSRNOT00000061129
G protein-coupled receptor 12
chr18_-_37132223 0.01 ENSRNOT00000091634
protein phosphatase 2, regulatory subunit B, beta
chr5_-_140024176 0.01 ENSRNOT00000016492
transmembrane and coiled-coil domains 2
chrX_+_68771100 0.01 ENSRNOT00000043872
StAR-related lipid transfer domain containing 8
chr17_+_69654170 0.01 ENSRNOT00000058351
aldo-keto reductase family 1, member C19
chr2_-_39007976 0.01 ENSRNOT00000064292
zinc finger, SWIM-type containing 6
chr6_-_91250138 0.01 ENSRNOT00000052408
ninein-like
chr18_+_61563053 0.01 ENSRNOT00000022845
gastrin releasing peptide
chrX_+_984798 0.01 ENSRNOT00000073016
zinc finger protein 182
chr6_+_107603580 0.01 ENSRNOT00000036430
dynein, axonemal, light chain 1
chr12_-_6078411 0.01 ENSRNOT00000001197
relaxin/insulin-like family peptide receptor 2
chr15_+_33885106 0.01 ENSRNOT00000024483
dehydrogenase/reductase 2
chr8_+_106816152 0.01 ENSRNOT00000047613
Fas apoptotic inhibitory molecule
chr13_-_55878094 0.01 ENSRNOT00000014218
LIM homeobox 9
chr7_-_54778848 0.01 ENSRNOT00000005399
GLI pathogenesis-related 1
chr8_+_107229832 0.01 ENSRNOT00000045821
Fas apoptotic inhibitory molecule
chr20_+_32450733 0.01 ENSRNOT00000036449
radial spoke head 4 homolog A
chr6_+_72891725 0.01 ENSRNOT00000038074
nucleotide binding protein-like
chr13_-_89343868 0.01 ENSRNOT00000058497
ENSRNOT00000035400
Fc fragment of IgG receptor IIb
chr5_+_154650632 0.01 ENSRNOT00000072132
zinc finger protein 46
chr3_+_149524667 0.01 ENSRNOT00000055345
BPI fold containing family A, member 2F
chr2_-_9472384 0.01 ENSRNOT00000084295
adhesion G protein-coupled receptor V1
chr2_+_189655702 0.01 ENSRNOT00000021502
GATA zinc finger domain containing 2B
chr17_-_69404323 0.01 ENSRNOT00000051342
ENSRNOT00000066282
aldo-keto reductase family 1, member C2
chr11_+_31893489 0.01 ENSRNOT00000042750
intersectin 1
chr2_-_39003552 0.01 ENSRNOT00000078884
zinc finger, SWIM-type containing 6
chr7_-_28711761 0.01 ENSRNOT00000006249
PARP1 binding protein
chrM_+_9451 0.01 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr10_-_104482838 0.01 ENSRNOT00000007246
RecQ like helicase 5
chr4_-_129619142 0.01 ENSRNOT00000047453
leiomodin 3
chr20_-_30975472 0.01 ENSRNOT00000066794
phosphatase domain containing, paladin 1
chr18_-_70184337 0.01 ENSRNOT00000020637
spindle and kinetochore associated complex subunit 1
chr7_+_23854846 0.01 ENSRNOT00000037290
BPI fold containing family C
chr10_-_27427686 0.01 ENSRNOT00000087475

chrM_+_7919 0.01 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr18_-_69780922 0.01 ENSRNOT00000079093
malic enzyme 2
chr15_-_36798814 0.01 ENSRNOT00000065764
centromere protein J
chr2_-_170301348 0.01 ENSRNOT00000088131
sucrase-isomaltase
chr2_-_188559882 0.01 ENSRNOT00000088199
tripartite motif-containing 46
chr18_-_67224566 0.01 ENSRNOT00000064947
DCC netrin 1 receptor
chr4_+_5848722 0.01 ENSRNOT00000082504

chr7_+_72599479 0.01 ENSRNOT00000018963

chr2_-_199354793 0.01 ENSRNOT00000023548
B-cell CLL/lymphoma 9
chr4_+_35279063 0.01 ENSRNOT00000011833
neurexophilin 1
chr4_+_156050054 0.01 ENSRNOT00000039855
C-type lectin domain family 4, member A
chr17_-_48810991 0.01 ENSRNOT00000067636
VPS41 HOPS complex subunit
chr10_-_104522241 0.01 ENSRNOT00000046010
ribosomal protein S18-like 1
chr8_+_126414220 0.01 ENSRNOT00000092142
5-azacytidine induced 2
chrY_-_1305026 0.01 ENSRNOT00000092901
ubiquitin specific peptidase 9, Y-linked
chr8_-_126390801 0.01 ENSRNOT00000089732

chr13_+_82574966 0.01 ENSRNOT00000003844
coiled-coil domain containing 181
chr10_+_65552897 0.01 ENSRNOT00000056217
sperm associated antigen 5
chr1_-_140477796 0.01 ENSRNOT00000067172
mitochondrial ribosomal protein L46
chr9_-_52238564 0.01 ENSRNOT00000005073
collagen type V alpha 2 chain
chr20_+_31234493 0.00 ENSRNOT00000000675
neuropeptide FF receptor 1
chrX_-_45284341 0.00 ENSRNOT00000045436
odorant binding protein I f
chr7_-_122329443 0.00 ENSRNOT00000032232
megakaryoblastic leukemia (translocation) 1
chr10_-_91122018 0.00 ENSRNOT00000080077
dephospho-CoA kinase domain containing
chr2_+_209433103 0.00 ENSRNOT00000024036
ligand dependent nuclear receptor interacting factor 1
chr20_+_4156858 0.00 ENSRNOT00000039553
butyrophilin-like 3
chr12_-_9864791 0.00 ENSRNOT00000073026
general transcription factor III A
chr7_+_71709157 0.00 ENSRNOT00000008211
carboxypeptidase Q
chrX_-_23139694 0.00 ENSRNOT00000033656
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_-_21553949 0.00 ENSRNOT00000031642
submaxillary gland androgen regulated protein 3B
chrX_+_45213228 0.00 ENSRNOT00000088538
odorant-binding protein
chr12_+_41486076 0.00 ENSRNOT00000057242
RBPJ interacting and tubulin associated 1
chr19_-_9765484 0.00 ENSRNOT00000016626
SET domain containing 6
chr9_+_8052210 0.00 ENSRNOT00000073659
adhesion G protein-coupled receptor E4
chrX_-_83864150 0.00 ENSRNOT00000073734
odorant binding protein I f
chr3_-_6054483 0.00 ENSRNOT00000084491
bromodomain containing 3
chrX_+_124894466 0.00 ENSRNOT00000080894
MCTS1, re-initiation and release factor
chr5_-_130085838 0.00 ENSRNOT00000035252
ELAV like RNA binding protein 4
chr8_+_132135187 0.00 ENSRNOT00000091791
transglutaminase 4
chr9_+_47536824 0.00 ENSRNOT00000049349
transmembrane protein 182
chr10_+_62981297 0.00 ENSRNOT00000031618
EF-hand calcium binding domain 5
chr8_+_115546893 0.00 ENSRNOT00000018932
DDB1 and CUL4 associated factor 1
chr15_-_33576331 0.00 ENSRNOT00000021851
solute carrier family 22, member 17
chr16_+_20657099 0.00 ENSRNOT00000027053
KxDL motif containing 1
chr13_+_85465792 0.00 ENSRNOT00000082991
ENSRNOT00000005277
transmembrane and coiled-coil domains 1
chrX_+_124631881 0.00 ENSRNOT00000009329
ATPase Na+/K+ transporting family member beta 4
chr13_+_79378733 0.00 ENSRNOT00000039221
tumor necrosis factor superfamily member 18
chr17_-_9762813 0.00 ENSRNOT00000033749
solute carrier family 34 member 1
chr5_-_99033107 0.00 ENSRNOT00000041306
heat shock protein family A (Hsp70) member 8
chr1_-_174350196 0.00 ENSRNOT00000055158
similar to predicted gene ICRFP703B1614Q5.5
chr5_-_28130803 0.00 ENSRNOT00000093186
solute carrier family 26 member 7
chr16_-_54137660 0.00 ENSRNOT00000085435
pericentriolar material 1
chr17_-_77527894 0.00 ENSRNOT00000032173
BEN domain containing 7
chr2_-_41871858 0.00 ENSRNOT00000039720
Grb2-binding adaptor protein, transmembrane
chr11_+_64472072 0.00 ENSRNOT00000042756
similar to ribosomal protein L27
chr6_+_34071428 0.00 ENSRNOT00000084212
matrilin 3
chr4_+_14070553 0.00 ENSRNOT00000077505
CD36 molecule
chrX_-_113228265 0.00 ENSRNOT00000060001
similar to 40S ribosomal protein S9
chrX_+_123486989 0.00 ENSRNOT00000083861
ENSRNOT00000061455
ubiquitin-conjugating enzyme E2A
chr7_-_120027026 0.00 ENSRNOT00000011215
caspase recruitment domain family, member 10
chr16_-_54137485 0.00 ENSRNOT00000014202
pericentriolar material 1
chr1_+_249574954 0.00 ENSRNOT00000074100
cleavage stimulation factor subunit 2, tau variant
chr7_+_35070284 0.00 ENSRNOT00000009578
nuclear receptor subfamily 2, group C, member 1
chr4_+_25635765 0.00 ENSRNOT00000009340
GTP binding protein 10
chr1_-_198706852 0.00 ENSRNOT00000024074
dCTP pyrophosphatase 1
chr9_+_43834310 0.00 ENSRNOT00000085720
cyclic nucleotide gated channel alpha 3
chr3_-_14112851 0.00 ENSRNOT00000092736
complement C5
chr18_+_73256085 0.00 ENSRNOT00000080660
haloacid dehalogenase-like hydrolase domain containing 2
chr14_+_108143869 0.00 ENSRNOT00000090003
ubiquitin specific peptidase 34
chr18_-_58423196 0.00 ENSRNOT00000025556
piezo-type mechanosensitive ion channel component 2
chr11_+_24266345 0.00 ENSRNOT00000046973
junctional adhesion molecule 2
chr17_+_36691875 0.00 ENSRNOT00000074314
similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a)
chr17_+_47301511 0.00 ENSRNOT00000092051
ENSRNOT00000087178
NME/NM23 family member 8
chr5_+_117509354 0.00 ENSRNOT00000048495
ribosomal protein S18-like
chr8_-_133002201 0.00 ENSRNOT00000008772
C-C motif chemokine receptor 1
chr9_+_47134034 0.00 ENSRNOT00000020108
interleukin 1 receptor-like 1
chrX_+_22342308 0.00 ENSRNOT00000079909
ENSRNOT00000087945
ENSRNOT00000077528
lysine demethylase 5C
chr2_-_181531978 0.00 ENSRNOT00000072029
neuropeptide Y receptor Y2
chr3_+_112228919 0.00 ENSRNOT00000011761
calpain 3
chr13_-_47397890 0.00 ENSRNOT00000005505
complement component 4 binding protein, beta
chr4_-_112707270 0.00 ENSRNOT00000009308
mitochondrial ribosomal protein L19
chr5_-_155709215 0.00 ENSRNOT00000018118
cell division cycle 42
chr1_-_126211439 0.00 ENSRNOT00000014988
tight junction protein 1
chr5_+_163867961 0.00 ENSRNOT00000081495

chr7_+_54859326 0.00 ENSRNOT00000039141
calcyphosine 2
chr1_+_162890475 0.00 ENSRNOT00000034886
glycerophosphodiester phosphodiesterase domain containing 4
chr17_-_76250537 0.00 ENSRNOT00000092693
UPF2 regulator of nonsense transcripts homolog (yeast)
chr14_-_10749120 0.00 ENSRNOT00000003046
COP9 signalosome subunit 4
chr6_-_76552559 0.00 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr10_-_40419054 0.00 ENSRNOT00000039040
coiled-coil domain containing 69
chr11_+_68633160 0.00 ENSRNOT00000063795
SEC22 homolog A, vesicle trafficking protein
chr10_+_15484795 0.00 ENSRNOT00000079826
transmembrane protein 8A
chr4_-_138830117 0.00 ENSRNOT00000008403
interleukin 5 receptor subunit alpha
chr1_-_1116926 0.00 ENSRNOT00000062027
retinoic acid early transcript 1L
chr6_+_73553210 0.00 ENSRNOT00000006562
A-kinase anchoring protein 6
chr15_+_26887767 0.00 ENSRNOT00000016674
olfactory receptor 1627
chr15_+_28023018 0.00 ENSRNOT00000090272
ribonuclease A family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)