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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hlf
Z-value: 0.74
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Transcription factors associated with Hlf
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hlf | rn6_v1_chr10_-_77918191_77918191 | 0.17 | 7.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_184188911 Show fit | 0.33 |
ENSRNOT00000055124
ENSRNOT00000014948 |
calcitonin-related polypeptide alpha |
|
| chr15_-_47442664 Show fit | 0.26 |
ENSRNOT00000072994
|
protease, serine, 55 |
|
| chr12_-_35979193 Show fit | 0.22 |
ENSRNOT00000071104
|
transmembrane protein 132B |
|
| chr5_-_168123395 Show fit | 0.22 |
ENSRNOT00000024932
|
period circadian clock 3 |
|
| chr15_+_87722221 Show fit | 0.21 |
ENSRNOT00000082688
|
sciellin |
|
| chr11_-_27080701 Show fit | 0.21 |
ENSRNOT00000002180
|
listerin E3 ubiquitin protein ligase 1 |
|
| chrX_-_10218583 Show fit | 0.20 |
ENSRNOT00000013382
|
nyctalopin |
|
| chr10_+_57239993 Show fit | 0.20 |
ENSRNOT00000067919
|
hypothetical protein LOC687707 |
|
| chr7_+_2435553 Show fit | 0.19 |
ENSRNOT00000065593
|
primase (DNA) subunit 1 |
|
| chr17_+_11683862 Show fit | 0.19 |
ENSRNOT00000024766
|
msh homeobox 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hlf
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0001983 | baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 0.0 | 0.3 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.1 | 0.2 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.0 | 0.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.0 | 0.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.2 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.0 | 0.2 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
| 0.0 | 0.2 | GO:0098880 | maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562) |
| 0.0 | 0.1 | GO:1902211 | regulation of prolactin signaling pathway(GO:1902211) |
| 0.0 | 0.1 | GO:0003322 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.2 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.1 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.0 | 0.1 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.0 | 0.1 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.0 | GO:0044317 | rod spherule(GO:0044317) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.0 | 0.2 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.0 | 0.2 | GO:0098879 | structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919) |
| 0.0 | 0.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.1 | GO:0052723 | inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.0 | 0.1 | GO:0019961 | interferon binding(GO:0019961) |
| 0.0 | 0.1 | GO:0017168 | 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168) |
| 0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.1 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.2 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.0 | 0.1 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |