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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hey1_Myc_Mxi1

Z-value: 1.02

Motif logo

Transcription factors associated with Hey1_Myc_Mxi1

Gene Symbol Gene ID Gene Info
ENSRNOG00000011593 hes-related family bHLH transcription factor with YRPW motif 1
ENSRNOG00000004500 myelocytomatosis oncogene
ENSRNOG00000034078 MAX interactor 1, dimerization protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mxi1rn6_v1_chr1_+_274030978_2740309780.602.9e-01Click!
Hey1rn6_v1_chr2_+_95320283_95320283-0.108.7e-01Click!
Mycrn6_v1_chr7_+_102586313_1025863130.069.3e-01Click!

Activity profile of Hey1_Myc_Mxi1 motif

Sorted Z-values of Hey1_Myc_Mxi1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_123119460 2.14 ENSRNOT00000028833
arginine vasopressin
chr2_-_197991198 1.61 ENSRNOT00000056322
circadian associated repressor of transcription
chr2_-_197991574 1.52 ENSRNOT00000085632
circadian associated repressor of transcription
chr2_-_187160373 0.87 ENSRNOT00000018961
neurotrophic receptor tyrosine kinase 1
chr2_-_260596777 0.80 ENSRNOT00000009370
LIM homeobox 8
chr17_-_9695292 0.77 ENSRNOT00000036162
proline rich 7 (synaptic)
chr14_+_4362717 0.62 ENSRNOT00000002887
BarH-like homeobox 2
chr4_+_33638709 0.58 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr16_+_49462889 0.57 ENSRNOT00000039909
ankyrin repeat domain 37
chr3_+_113415774 0.57 ENSRNOT00000056151
small EDRK-rich factor 2
chr13_-_90814119 0.47 ENSRNOT00000011208
transgelin 2
chr5_-_147953093 0.47 ENSRNOT00000075270
KH RNA binding domain containing, signal transduction associated 1
chr10_-_44746549 0.47 ENSRNOT00000003841
family with sequence similarity 183, member B
chr1_+_240908483 0.45 ENSRNOT00000019367
Kruppel-like factor 9
chr6_+_42852683 0.43 ENSRNOT00000079185
ornithine decarboxylase 1
chr1_+_73719005 0.42 ENSRNOT00000025110
CDC42 effector protein 5
chr10_+_91710495 0.40 ENSRNOT00000033276
reprimo-like
chr4_-_165629996 0.40 ENSRNOT00000068185
ENSRNOT00000007427
Y box binding protein 3
chr9_-_16848503 0.39 ENSRNOT00000024815
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr3_-_66417741 0.37 ENSRNOT00000007662
neuronal differentiation 1
chr10_-_85574889 0.36 ENSRNOT00000072274
hypothetical protein LOC691153
chr20_-_5533448 0.35 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr20_-_5533600 0.34 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr1_+_168964202 0.34 ENSRNOT00000089102
hemoglobin subunit beta-2-like
chr9_+_98490608 0.33 ENSRNOT00000027232
kelch-like family member 30
chr17_-_13393243 0.32 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr3_+_147643250 0.30 ENSRNOT00000000013
transcription factor 15
chr12_-_31323810 0.29 ENSRNOT00000001247
RAN, member RAS oncogene family
chr1_+_240776969 0.29 ENSRNOT00000049732
similar to ribosomal protein S12
chr10_-_81653717 0.29 ENSRNOT00000003611
NME/NM23 nucleoside diphosphate kinase 2
chr6_+_137997335 0.29 ENSRNOT00000006872
transmembrane protein 121
chr3_-_120306551 0.28 ENSRNOT00000021082
mal, T-cell differentiation protein-like
chr3_+_61685619 0.28 ENSRNOT00000002140
homeo box D1
chr10_+_16542882 0.27 ENSRNOT00000028146
stanniocalcin 2
chr4_-_123118186 0.27 ENSRNOT00000038096
coiled-coil-helix-coiled-coil-helix domain containing 4
chr15_-_27849974 0.27 ENSRNOT00000012790
O-sialoglycoprotein endopeptidase
chr1_-_168972725 0.26 ENSRNOT00000090422
hemoglobin subunit beta
chr12_-_23841049 0.26 ENSRNOT00000031555
heat shock protein family B (small) member 1
chr7_+_128500011 0.26 ENSRNOT00000074625
family with sequence similarity 19 member A5, C-C motif chemokine like
chr9_-_113331319 0.25 ENSRNOT00000020681
VAMP associated protein A
chr1_-_214455039 0.25 ENSRNOT00000071028
RNA polymerase II subunit L
chrX_-_32355296 0.25 ENSRNOT00000081652
ENSRNOT00000065075
adaptor-related protein complex 1, sigma 2 subunit
chr5_+_150080072 0.25 ENSRNOT00000047917
transmembrane protein 200B
chr1_-_78212350 0.25 ENSRNOT00000071098
InaF-motif containing 1
chr15_+_37790141 0.24 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr11_+_32211115 0.24 ENSRNOT00000087452
mitochondrial ribosomal protein S6
chr1_+_82452469 0.24 ENSRNOT00000028026
exosome component 5
chr2_+_189400696 0.24 ENSRNOT00000046919
ENSRNOT00000089801
similar to NICE-3
chr4_+_83391283 0.24 ENSRNOT00000031365
cAMP responsive element binding protein 5
chr5_-_137372524 0.23 ENSRNOT00000009061
transmembrane protein 125
chr8_-_61917125 0.23 ENSRNOT00000085049
similar to human chromosome 15 open reading frame 39
chr5_-_166726794 0.23 ENSRNOT00000022799
solute carrier family 25 member 33
chr7_-_18683440 0.23 ENSRNOT00000068323
ribosomal protein S28
chr14_-_11198194 0.23 ENSRNOT00000003083
enolase-phosphatase 1
chr20_-_13706205 0.22 ENSRNOT00000038623
derlin 3
chr2_-_187668677 0.21 ENSRNOT00000056898
ENSRNOT00000092563
TSSK6 activating co-chaperone
chr9_-_97065817 0.21 ENSRNOT00000026419
gastrulation brain homeobox 2
chr1_-_265899958 0.21 ENSRNOT00000026013
paired-like homeodomain 3
chr7_+_3332788 0.21 ENSRNOT00000010180
Cd63 molecule
chr1_+_163445527 0.21 ENSRNOT00000020520
leucine rich repeat containing 32
chr3_-_7498555 0.21 ENSRNOT00000017725
BarH-like homeobox 1
chr10_+_84135116 0.20 ENSRNOT00000031035
homeo box B7
chr9_+_69953440 0.20 ENSRNOT00000034740
eukaryotic translation elongation factor 1 beta 2
chr10_-_40375605 0.20 ENSRNOT00000014464
annexin A6
chr10_-_83898527 0.20 ENSRNOT00000009815
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr11_-_60613718 0.20 ENSRNOT00000002906
autophagy related 3
chr1_+_261229347 0.20 ENSRNOT00000018485
ubiquitin domain containing 1
chr10_+_83476107 0.19 ENSRNOT00000075733
prohibitin
chr11_-_34598102 0.19 ENSRNOT00000068743
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_199159125 0.19 ENSRNOT00000025618
BCL tumor suppressor 7C
chr15_+_27849979 0.19 ENSRNOT00000013176
apurinic/apyrimidinic endodeoxyribonuclease 1
chr8_+_117117430 0.19 ENSRNOT00000073247
glutathione peroxidase 1
chr5_+_137371825 0.19 ENSRNOT00000072816
transmembrane protein 125
chr1_-_101123402 0.19 ENSRNOT00000027976

chr7_-_11648322 0.19 ENSRNOT00000026871
growth arrest and DNA-damage-inducible, beta
chr1_+_12823363 0.19 ENSRNOT00000086790
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr3_-_81282157 0.19 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr3_-_8852192 0.18 ENSRNOT00000022786
dolichol kinase
chr5_-_152464850 0.18 ENSRNOT00000021937
zinc finger protein 593
chr19_+_16415636 0.18 ENSRNOT00000089975
iroquois homeobox 5
chr7_+_141370491 0.18 ENSRNOT00000087662
glycerol-3-phosphate dehydrogenase 1
chr1_-_259357056 0.18 ENSRNOT00000022000
PDZ and LIM domain 1
chr4_-_129430251 0.18 ENSRNOT00000067881
family with sequence similarity 19 member A4, C-C motif chemokine like
chr1_+_80135391 0.18 ENSRNOT00000021893
G protein-coupled receptor 4
chr10_+_16970626 0.18 ENSRNOT00000005383
dual specificity phosphatase 1
chr6_+_136150785 0.17 ENSRNOT00000078211
ENSRNOT00000015308
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
chr1_+_81230612 0.17 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr2_+_127538659 0.17 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr4_-_78879294 0.17 ENSRNOT00000084543
insulin-like growth factor 2 mRNA binding protein 3
chr14_-_33580566 0.17 ENSRNOT00000063942
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr9_-_9702306 0.17 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr11_-_83985385 0.17 ENSRNOT00000002334
endothelin-converting enzyme 2-like
chr10_+_55940533 0.17 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr5_-_166924136 0.17 ENSRNOT00000085251
splA/ryanodine receptor domain and SOCS box containing 1
chr4_+_7257752 0.17 ENSRNOT00000088357
transmembrane and ubiquitin-like domain containing 1
chrX_+_156863754 0.17 ENSRNOT00000083611
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr1_+_33910912 0.17 ENSRNOT00000044690
iroquois homeobox 1
chr7_+_18683553 0.17 ENSRNOT00000009425
NADH:ubiquinone oxidoreductase subunit A7
chr17_-_9234766 0.17 ENSRNOT00000015893

chr19_+_37226186 0.17 ENSRNOT00000075933
ENSRNOT00000065013
heat shock transcription factor 4
chr17_+_85356042 0.17 ENSRNOT00000022201
COMM domain containing 3
chr5_-_157820889 0.16 ENSRNOT00000024326
MRT4 homolog, ribosome maturation factor
chr10_-_81587858 0.16 ENSRNOT00000003582
UTP18 small subunit processome component
chr12_+_12738812 0.16 ENSRNOT00000092233
ENSRNOT00000001379
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr2_+_206064394 0.16 ENSRNOT00000077739
synaptotagmin 6
chr15_-_34352673 0.16 ENSRNOT00000064916
neural precursor cell expressed, developmentally down-regulated 8
chr8_-_66863476 0.16 ENSRNOT00000018820
ribosomal protein lateral stalk subunit P1
chrX_+_43497763 0.16 ENSRNOT00000005014
peroxiredoxin 4
chr5_-_145423172 0.16 ENSRNOT00000081919
gap junction protein, beta 5
chr1_+_220869805 0.16 ENSRNOT00000015962
cofilin 1
chr5_+_150725654 0.15 ENSRNOT00000089852
ENSRNOT00000017740
DnaJ heat shock protein family (Hsp40) member C8
chr10_-_57275708 0.15 ENSRNOT00000005370
profilin 1
chr4_-_120817377 0.15 ENSRNOT00000021826
podocalyxin-like 2
chr8_-_36314811 0.15 ENSRNOT00000013243
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr17_+_9837402 0.15 ENSRNOT00000076436
RAB24, member RAS oncogene family
chr14_+_86673775 0.15 ENSRNOT00000091873
ENSRNOT00000079015
peptidylprolyl isomerase A
chr5_+_169506138 0.15 ENSRNOT00000014904
ribosomal protein L22
chr1_-_82452281 0.15 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr10_+_55626741 0.15 ENSRNOT00000008492
aurora kinase B
chr6_-_137084739 0.15 ENSRNOT00000060943
transmembrane protein 179
chr15_-_45376476 0.15 ENSRNOT00000065838
deleted in lymphocytic leukemia, 7
chr8_-_52814188 0.15 ENSRNOT00000087265
ENSRNOT00000047633
RNA exonuclease 2
chr4_-_157679962 0.14 ENSRNOT00000050443
glyceraldehyde-3-phosphate dehydrogenase
chr10_-_63499390 0.14 ENSRNOT00000032934
basic helix-loop-helix family, member a9
chr1_+_100393303 0.14 ENSRNOT00000026251
synaptotagmin 3
chrX_+_65226748 0.14 ENSRNOT00000076181
moesin
chr3_+_71020534 0.14 ENSRNOT00000007276
zinc finger CCCH-type containing 15
chr10_-_86509454 0.14 ENSRNOT00000009454
IKAROS family zinc finger 3
chr1_-_24191908 0.14 ENSRNOT00000061157
serum/glucocorticoid regulated kinase 1
chr1_+_222229835 0.14 ENSRNOT00000051749
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr20_+_31265483 0.14 ENSRNOT00000079584
ENSRNOT00000000674
pyrophosphatase (inorganic) 1
chr18_+_70996044 0.14 ENSRNOT00000024950
ENSRNOT00000066336
dymeclin
chr7_+_11724962 0.14 ENSRNOT00000026551
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_123494742 0.14 ENSRNOT00000073268
solute carrier family 41, member 3
chr8_-_115140080 0.14 ENSRNOT00000015851
aminoacylase 1
chr1_-_78333321 0.14 ENSRNOT00000020402
SUMO1 activating enzyme subunit 1
chr1_+_40816107 0.14 ENSRNOT00000060767
A-kinase anchoring protein 12
chr17_-_9837293 0.13 ENSRNOT00000091320
ENSRNOT00000022134
PRELI domain containing 1
chr3_-_173953684 0.13 ENSRNOT00000090468
protein phosphatase 1, regulatory subunit 3D
chr6_-_26486695 0.13 ENSRNOT00000073236
keratinocyte associated protein 3
chr15_-_61564695 0.13 ENSRNOT00000068216
regulator of cell cycle
chr20_+_18493538 0.13 ENSRNOT00000000749
CDGSH iron sulfur domain 1
chr6_+_26797126 0.13 ENSRNOT00000010586
cell growth regulator with EF hand domain 1
chr7_-_18634079 0.13 ENSRNOT00000010031
angiopoietin-like 4
chr2_+_189106039 0.13 ENSRNOT00000028210
ubiquitin conjugating enzyme E2 Q1
chr1_-_164143818 0.13 ENSRNOT00000022557
diacylglycerol O-acyltransferase 2
chr3_+_177374812 0.13 ENSRNOT00000024096
RNA polymerase III subunit K
chr4_+_6827429 0.13 ENSRNOT00000071737
Ras homolog enriched in brain
chr8_-_62386264 0.13 ENSRNOT00000026165
complexin 3
chr19_+_14508616 0.13 ENSRNOT00000019192
heme oxygenase 1
chr9_-_10054359 0.13 ENSRNOT00000072001
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr2_+_19823234 0.13 ENSRNOT00000022348
ribosomal protein S23
chr10_-_14022452 0.13 ENSRNOT00000016554
neuropeptide W
chr16_-_81706664 0.13 ENSRNOT00000026580
lysosomal-associated membrane protein 1
chr11_+_86890585 0.13 ENSRNOT00000002579
RAN binding protein 1
chr1_-_198706852 0.13 ENSRNOT00000024074
dCTP pyrophosphatase 1
chr16_+_80826681 0.12 ENSRNOT00000000123
coordinator of PRMT5 and differentiation stimulator
chr7_+_77966722 0.12 ENSRNOT00000006142
collagen triple helix repeat containing 1
chr3_-_10375826 0.12 ENSRNOT00000093365
argininosuccinate synthase 1
chr19_-_57422093 0.12 ENSRNOT00000025512
similar to RIKEN cDNA 2310022B05
chr7_-_73270308 0.12 ENSRNOT00000007430
reactive intermediate imine deaminase A homolog
chr10_+_40208223 0.12 ENSRNOT00000000772
histidine triad nucleotide binding protein 1
chr1_-_226255886 0.12 ENSRNOT00000027842
flap structure-specific endonuclease 1
chr1_-_89358166 0.12 ENSRNOT00000044532
myelin-associated glycoprotein
chr7_+_72772440 0.12 ENSRNOT00000009989
metadherin
chr1_-_91042230 0.12 ENSRNOT00000073107
DNA-directed RNA polymerase II subunit RPB9
chr7_-_140770647 0.12 ENSRNOT00000081784
complement C1q like 4
chr1_-_100980340 0.12 ENSRNOT00000064272
protein arginine methyltransferase 1
chr15_-_44860604 0.12 ENSRNOT00000018637
neurofilament medium
chr15_+_2631529 0.12 ENSRNOT00000018897
catechol-O-methyltransferase domain containing 1
chr10_+_10889488 0.12 ENSRNOT00000071746
UBA-like domain containing 1
chrX_-_135041027 0.12 ENSRNOT00000006484
zinc finger, DHHC-type containing 9
chr12_-_16934706 0.12 ENSRNOT00000001720
MAF bZIP transcription factor K
chr10_+_89376530 0.12 ENSRNOT00000028089
Rho family GTPase 2
chr10_-_56531483 0.12 ENSRNOT00000022343
eukaryotic translation initiation factor 5A
chr12_+_8976585 0.12 ENSRNOT00000071796
proteasome maturation protein-like
chr10_+_88459490 0.12 ENSRNOT00000080231
ENSRNOT00000067559
tetratricopeptide repeat domain 25
chr14_+_34354503 0.12 ENSRNOT00000002941
neuromedin U
chr2_-_235257464 0.11 ENSRNOT00000093472
GAR1 ribonucleoprotein
chr1_-_84008293 0.11 ENSRNOT00000002053
small nuclear ribonucleoprotein polypeptide A
chr2_+_197682000 0.11 ENSRNOT00000066821
HORMA domain containing 1
chr7_-_13751271 0.11 ENSRNOT00000009931
solute carrier family 1 member 6
chr1_-_222178725 0.11 ENSRNOT00000028697
estrogen related receptor, alpha
chr14_+_60764409 0.11 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr1_+_126979575 0.11 ENSRNOT00000016916
ENSRNOT00000081746
selenoprotein S
chr4_-_117296082 0.11 ENSRNOT00000021097
early growth response 4
chr19_+_55917736 0.11 ENSRNOT00000020635
ribosomal protein L13
chr6_-_93562314 0.11 ENSRNOT00000010871
ENSRNOT00000088790
translocase of inner mitochondrial membrane 9
chr10_+_85257876 0.11 ENSRNOT00000014752
mitochondrial ribosomal protein L45
chr8_+_66296883 0.11 ENSRNOT00000018467
transducin-like enhancer of split 3
chr2_+_188561429 0.11 ENSRNOT00000076458
ENSRNOT00000027867
keratinocyte associated protein 2
chr10_+_64930023 0.11 ENSRNOT00000071102

chr5_-_138470096 0.11 ENSRNOT00000011392
phosphopantothenoylcysteine synthetase
chr10_-_13536899 0.11 ENSRNOT00000008537
amidohydrolase domain containing 2
chr17_-_66397653 0.11 ENSRNOT00000024098
actinin alpha 2
chr5_-_24631679 0.11 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr12_-_30268990 0.11 ENSRNOT00000079546
vitamin K epoxide reductase complex subunit 1-like protein 1
chr15_+_27850151 0.11 ENSRNOT00000087958
apurinic/apyrimidinic endodeoxyribonuclease 1
chr2_-_211017778 0.11 ENSRNOT00000026883
synaptophysin-like 2
chr1_+_40879747 0.11 ENSRNOT00000083702
A-kinase anchoring protein 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Hey1_Myc_Mxi1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.2 0.8 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 0.5 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.4 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.1 3.1 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.6 GO:2000851 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.3 GO:1903544 cellular response to interleukin-11(GO:0071348) response to butyrate(GO:1903544)
0.1 0.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.3 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.1 0.2 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.1 0.2 GO:0009609 response to symbiotic bacterium(GO:0009609)
0.1 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.2 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.2 GO:2000771 regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
0.1 0.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.2 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0034395 heme oxidation(GO:0006788) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.0 0.2 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.3 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:2001137 actin filament uncapping(GO:0051695) positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0060468 peptidyl-tyrosine sulfation(GO:0006478) negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0072143 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:2000417 negative regulation of phagocytosis, engulfment(GO:0060101) negative regulation of eosinophil migration(GO:2000417)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0061198 maintenance of chromatin silencing(GO:0006344) fungiform papilla formation(GO:0061198)
0.0 0.1 GO:1903189 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of removal of superoxide radicals(GO:1904833) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0034443 plasma lipoprotein particle oxidation(GO:0034441) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.0 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.2 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.0 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0060683 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
0.0 0.1 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.0 0.0 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.0 GO:1904373 response to kainic acid(GO:1904373)
0.0 0.0 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0014063 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of serotonin secretion(GO:0014063)
0.0 0.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0060631 meiotic DNA double-strand break formation(GO:0042138) regulation of meiosis I(GO:0060631)
0.0 0.0 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.0 GO:0046016 positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.1 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0015746 citrate transport(GO:0015746)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:1904874 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.0 0.0 GO:0036166 phenotypic switching(GO:0036166)
0.0 0.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.0 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.0 GO:1903165 response to polycyclic arene(GO:1903165)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0014858 positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:1904586 response to sodium phosphate(GO:1904383) response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
0.0 0.1 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.0 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.0 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.0 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.0 0.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0061474 phagolysosome membrane(GO:0061474)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0044393 TCR signalosome(GO:0036398) microspike(GO:0044393)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.0 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.0 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.2 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.4 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0017098 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0016823 oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0019825 oxygen binding(GO:0019825)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.0 GO:1904288 BAT3 complex binding(GO:1904288)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)