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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Hdx
Z-value: 0.44
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Transcription factors associated with Hdx
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hdx | rn6_v1_chrX_-_83151511_83151511 | -0.77 | 1.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_32153794 Show fit | 0.39 |
ENSRNOT00000005348
|
transmembrane protein 27 |
|
| chr4_+_94696965 Show fit | 0.19 |
ENSRNOT00000064696
|
glutamate ionotropic receptor delta type subunit 2 |
|
| chr15_+_24159647 Show fit | 0.14 |
ENSRNOT00000082675
|
galectin 3 |
|
| chr2_+_140708397 Show fit | 0.13 |
ENSRNOT00000088846
|
microsomal glutathione S-transferase 2 |
|
| chr14_+_34354503 Show fit | 0.12 |
ENSRNOT00000002941
|
neuromedin U |
|
| chr20_+_6351458 Show fit | 0.10 |
ENSRNOT00000091731
|
cyclin-dependent kinase inhibitor 1A |
|
| chrX_+_29504349 Show fit | 0.10 |
ENSRNOT00000005981
|
transcription elongation factor A N-terminal and central domain containing |
|
| chr1_-_89358166 Show fit | 0.10 |
ENSRNOT00000044532
|
myelin-associated glycoprotein |
|
| chr11_+_67451549 Show fit | 0.10 |
ENSRNOT00000042777
|
stefin A2-like 2 |
|
| chr10_+_71202456 Show fit | 0.10 |
ENSRNOT00000076893
|
HNF1 homeobox B |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hdx
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.2 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.0 | 0.1 | GO:1903769 | negative regulation of cell proliferation in bone marrow(GO:1903769) |
| 0.0 | 0.1 | GO:0039020 | regulation of pronephros size(GO:0035565) pronephric nephron tubule development(GO:0039020) hepatoblast differentiation(GO:0061017) |
| 0.0 | 0.1 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.0 | 0.1 | GO:0046440 | lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.0 | 0.1 | GO:0036233 | glycine import(GO:0036233) |
| 0.0 | 0.0 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.0 | 0.0 | GO:0071661 | granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) |
| 0.0 | 0.0 | GO:0070637 | nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.0 | 0.1 | GO:0097453 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 0.0 | 0.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 0.0 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.0 | 0.1 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.0 | 0.1 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.0 | 0.1 | GO:0001565 | phorbol ester receptor activity(GO:0001565) |
| 0.0 | 0.1 | GO:0050785 | IgE binding(GO:0019863) advanced glycation end-product receptor activity(GO:0050785) |
| 0.0 | 0.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.1 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.0 | 0.1 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.0 | 0.1 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.1 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |