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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Glis2

Z-value: 0.32

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Transcription factors associated with Glis2

Gene Symbol Gene ID Gene Info
ENSRNOG00000004766 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Glis2rn6_v1_chr10_-_11174861_111748610.079.1e-01Click!

Activity profile of Glis2 motif

Sorted Z-values of Glis2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_123445613 0.37 ENSRNOT00000070937
shisa family member 8
chr10_-_88551056 0.15 ENSRNOT00000032737
zinc finger protein 385C
chr12_-_38782010 0.14 ENSRNOT00000001813
WD repeat domain 66
chr5_-_151709877 0.12 ENSRNOT00000080602
TMF1-regulated nuclear protein 1
chr7_+_11737293 0.09 ENSRNOT00000046059
leucine rich repeat and Ig domain containing 3
chr17_-_1093873 0.09 ENSRNOT00000086130
patched 1
chr7_-_28040510 0.08 ENSRNOT00000005674
achaete-scute family bHLH transcription factor 1
chr16_-_50501716 0.07 ENSRNOT00000067486
FAT atypical cadherin 1
chr10_+_72486152 0.07 ENSRNOT00000004193
similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1)
chr14_-_35149608 0.07 ENSRNOT00000003050
ENSRNOT00000090654
KIT proto-oncogene receptor tyrosine kinase
chr10_+_91710495 0.06 ENSRNOT00000033276
reprimo-like
chr1_-_87468288 0.06 ENSRNOT00000042207
signal-induced proliferation-associated 1 like 3
chr10_+_40553180 0.06 ENSRNOT00000087763
solute carrier family 36 member 1
chr10_-_85938085 0.06 ENSRNOT00000043561
plexin domain containing 1
chr4_-_123494742 0.06 ENSRNOT00000073268
solute carrier family 41, member 3
chr3_+_148541909 0.05 ENSRNOT00000012187
CCM2 like scaffolding protein
chr10_+_61403130 0.05 ENSRNOT00000092490
ENSRNOT00000077649
coiled-coil domain containing 92B
chr12_-_47793534 0.05 ENSRNOT00000001588
family with sequence similarity 222, member A
chr10_-_82197520 0.05 ENSRNOT00000092024
calcium voltage-gated channel subunit alpha1 G
chr7_-_120490061 0.05 ENSRNOT00000016247
solute carrier family 16 member 8
chr14_+_34389991 0.05 ENSRNOT00000002953
phosducin-like 2
chr15_+_57505449 0.05 ENSRNOT00000064945
siah E3 ubiquitin protein ligase family member 3
chr3_+_148579920 0.05 ENSRNOT00000012432
HCK proto-oncogene, Src family tyrosine kinase
chr12_+_2046472 0.05 ENSRNOT00000001289
zinc finger protein 358
chr15_+_34520142 0.05 ENSRNOT00000074659
NYN domain and retroviral integrase containing
chr17_+_80882666 0.05 ENSRNOT00000024430
vimentin
chr12_+_9360672 0.05 ENSRNOT00000088957
fms-related tyrosine kinase 3
chr1_-_219719272 0.05 ENSRNOT00000026152
synaptotagmin 12
chr1_-_101596822 0.05 ENSRNOT00000028490
fibroblast growth factor 21
chr1_-_184188911 0.04 ENSRNOT00000055124
ENSRNOT00000014948
calcitonin-related polypeptide alpha
chr6_-_107325345 0.04 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
NUMB, endocytic adaptor protein
chr10_+_56381813 0.04 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr11_+_60073383 0.04 ENSRNOT00000087508
transgelin 3
chr8_+_130581062 0.04 ENSRNOT00000014323
family with sequence similarity 198, member A
chr11_+_57505005 0.04 ENSRNOT00000002942
transgelin-3
chr3_-_72289310 0.04 ENSRNOT00000038250
reticulon 4 receptor-like 2
chr16_+_2743823 0.04 ENSRNOT00000087873
Rho guanine nucleotide exchange factor 3
chr1_+_124625985 0.04 ENSRNOT00000021068
OTU deubiquitinase 7A
chr9_+_16702460 0.04 ENSRNOT00000061432
protein tyrosine kinase 7
chr1_+_177193735 0.03 ENSRNOT00000043017
MICAL C-terminal like
chr1_-_164308317 0.03 ENSRNOT00000022983
serpin family H member 1
chr15_+_40665041 0.03 ENSRNOT00000018300
APC membrane recruitment protein 2
chr9_-_79545024 0.03 ENSRNOT00000021152
melanoregulin
chr18_-_71614980 0.03 ENSRNOT00000032563
peroxisomal biogenesis factor 19-like
chr7_+_70556019 0.03 ENSRNOT00000087495
ENSRNOT00000008120
dynactin subunit 2
chr14_-_28856214 0.03 ENSRNOT00000044659
adhesion G protein-coupled receptor L3
chr12_+_25119355 0.03 ENSRNOT00000034629
linker for activation of T cells family, member 2
chr3_-_143063983 0.03 ENSRNOT00000006329
NSF attachment protein beta
chr7_-_12311149 0.03 ENSRNOT00000046886
DAZ associated protein 1
chr17_+_23135985 0.03 ENSRNOT00000090794
neural precursor cell expressed, developmentally down-regulated 9
chr5_-_58078545 0.03 ENSRNOT00000075777
ciliary neurotrophic factor receptor
chr7_-_129724303 0.03 ENSRNOT00000006034
bromodomain containing 1
chr12_+_15857805 0.03 ENSRNOT00000001667
IQ motif containing E
chr9_-_81565416 0.03 ENSRNOT00000083582
angio-associated, migratory cell protein
chr10_-_70202398 0.03 ENSRNOT00000076089
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr17_-_44840131 0.02 ENSRNOT00000083417
histone cluster 1, H3b
chr3_-_148407778 0.02 ENSRNOT00000011262
forkhead box S1
chr1_+_100832324 0.02 ENSRNOT00000056364
interleukin 4 induced 1
chr8_-_13109487 0.02 ENSRNOT00000061616
angiomotin-like 1
chr8_+_116754178 0.02 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chr11_-_89260297 0.02 ENSRNOT00000057502
scaffolding protein involved in DNA repair
chr1_-_127292090 0.02 ENSRNOT00000016959
leucine-rich repeat kinase 1
chr20_-_4508197 0.02 ENSRNOT00000086027
ENSRNOT00000000514
complement component 4A (Rodgers blood group)
chr9_-_110936631 0.02 ENSRNOT00000064431
F-box and leucine-rich repeat protein 17
chr1_+_170471238 0.02 ENSRNOT00000076961
ENSRNOT00000075597
ENSRNOT00000076631
ENSRNOT00000076783
translocase of inner mitochondrial membrane 10B
dynein heavy chain domain 1
chr5_-_150925727 0.02 ENSRNOT00000017618
XK related 8
chr15_-_38276159 0.02 ENSRNOT00000084698
ENSRNOT00000015233
mitochondrial calcium uptake 2
chr6_+_123897956 0.02 ENSRNOT00000005167
tyrosyl-DNA phosphodiesterase 1
chr14_+_85250042 0.02 ENSRNOT00000057407
adaptor-related protein complex 1, beta 1 subunit
chr20_-_1980101 0.02 ENSRNOT00000084582
ENSRNOT00000085050
ENSRNOT00000082545
ENSRNOT00000088396
gamma-aminobutyric acid type B receptor subunit 1
chr10_+_107455845 0.02 ENSRNOT00000004373
C1q and tumor necrosis factor related protein 1
chr7_-_119768082 0.02 ENSRNOT00000009612
somatostatin receptor 3
chr1_+_199196059 0.02 ENSRNOT00000090428
F-box and leucine-rich repeat protein 19
chr3_+_80556668 0.02 ENSRNOT00000079118
Rho GTPase activating protein 1
chr16_-_18860086 0.02 ENSRNOT00000074814
SIN3 transcription regulator family member B
chr2_-_164126783 0.02 ENSRNOT00000016843
short stature homeobox 2
chr11_+_60072727 0.02 ENSRNOT00000090230
transgelin 3
chr3_-_148312791 0.02 ENSRNOT00000091419
Bcl2-like 1
chr13_+_90514336 0.02 ENSRNOT00000088996
ENSRNOT00000085377
peroxisomal biogenesis factor 19
chr12_-_13157570 0.02 ENSRNOT00000001437
ENSRNOT00000067332
ENSRNOT00000092238
diacylglycerol lipase, beta
chr20_+_28572242 0.02 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr19_+_37226186 0.02 ENSRNOT00000075933
ENSRNOT00000065013
heat shock transcription factor 4
chr1_-_220502272 0.02 ENSRNOT00000041238
kinesin light chain 2
chr2_+_62360754 0.01 ENSRNOT00000017276
golgi phosphoprotein 3
chrX_+_65566047 0.01 ENSRNOT00000092103
hephaestin
chr10_-_57436368 0.01 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr18_-_24057917 0.01 ENSRNOT00000023874
Ras-like without CAAX 2
chr20_-_2212171 0.01 ENSRNOT00000085912
tripartite motif-containing 26
chr8_+_133197032 0.01 ENSRNOT00000075564
chemokine (C-C motif) receptor 5
chr20_+_11114164 0.01 ENSRNOT00000001602
1-acylglycerol-3-phosphate O-acyltransferase 3
chr3_+_149424392 0.01 ENSRNOT00000044574
BPI fold containing family B, member 4
chr20_-_2211995 0.01 ENSRNOT00000077201
tripartite motif-containing 26
chrX_-_123515720 0.01 ENSRNOT00000092343
NFKB repressing factor
chr11_-_88273254 0.01 ENSRNOT00000002533
mitogen activated protein kinase 1
chr2_-_198719202 0.01 ENSRNOT00000028801
RNA polymerase III subunit G like
chr13_-_89594738 0.01 ENSRNOT00000004641
translocase of outer mitochondrial membrane 40 like
chr1_+_82480195 0.01 ENSRNOT00000028051
transforming growth factor, beta 1
chr10_-_37311625 0.01 ENSRNOT00000043343
jade family PHD finger 2
chr7_+_70328391 0.01 ENSRNOT00000075544
methyltransferase like 1
chr1_+_123015746 0.01 ENSRNOT00000013483
MAGE family member L2
chr5_-_138470096 0.01 ENSRNOT00000011392
phosphopantothenoylcysteine synthetase
chr3_-_111469518 0.01 ENSRNOT00000006874
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr12_+_22466601 0.01 ENSRNOT00000074544

chr20_-_10257044 0.01 ENSRNOT00000068289
WD repeat domain 4
chr3_+_111160205 0.01 ENSRNOT00000019392
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
chr18_+_15738809 0.01 ENSRNOT00000075444
microtubule-associated protein, RP/EB family, member 2
chr7_+_70364813 0.01 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_43538160 0.01 ENSRNOT00000089217
CCR4-NOT transcription complex, subunit 8
chrX_+_65226748 0.01 ENSRNOT00000076181
moesin
chr12_+_25036605 0.01 ENSRNOT00000001996
ENSRNOT00000084427
LIM domain kinase 1
chrX_+_71324365 0.01 ENSRNOT00000004911
non-POU domain containing, octamer-binding
chr2_+_196139755 0.01 ENSRNOT00000040501
phosphatidylinositol 4-kinase beta
chrX_+_5825711 0.01 ENSRNOT00000037360
EF-hand domain containing 2
chr16_-_7007287 0.01 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr4_+_147333056 0.01 ENSRNOT00000012137
peroxisome proliferator-activated receptor gamma
chr11_+_45751812 0.01 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr16_-_23156962 0.01 ENSRNOT00000018543
SH2 domain containing 4A
chr1_-_219853329 0.01 ENSRNOT00000026169
leucine rich repeat and fibronectin type III domain containing 4
chr10_+_67494984 0.01 ENSRNOT00000056273
ArfGAP with dual PH domains 2
chr10_+_90984227 0.01 ENSRNOT00000003890
ENSRNOT00000093707
coiled-coil domain containing 103
chr1_+_85162452 0.01 ENSRNOT00000093347
p21 (RAC1) activated kinase 4
chr9_+_81656116 0.01 ENSRNOT00000083421
solute carrier family 11 member 1
chr2_-_178057157 0.00 ENSRNOT00000091135
Rap guanine nucleotide exchange factor 2
chr20_+_30791422 0.00 ENSRNOT00000047394
ENSRNOT00000000683
thymus, brain and testes associated
chr8_+_21890319 0.00 ENSRNOT00000027949
hypothetical protein LOC500956
chr20_-_2678141 0.00 ENSRNOT00000072377
ENSRNOT00000083833
complement component 4A (Rodgers blood group)
chr12_+_23544287 0.00 ENSRNOT00000001938
ORAI calcium release-activated calcium modulator 2
chr12_-_29958050 0.00 ENSRNOT00000058725
transmembrane protein 248
chr15_+_34234193 0.00 ENSRNOT00000077584
DDB1 and CUL4 associated factor 11
chr5_+_135574172 0.00 ENSRNOT00000023416
testis-specific kinase 2
chr7_+_143629455 0.00 ENSRNOT00000073951
keratin 18
chr2_-_188645196 0.00 ENSRNOT00000083793
ephrin A3
chr6_+_136084605 0.00 ENSRNOT00000092806
microtubule affinity regulating kinase 3
chr3_+_2506426 0.00 ENSRNOT00000015242
leucine rich repeat containing 26
chr4_+_27175243 0.00 ENSRNOT00000009985
cytochrome P450, family 51
chr4_-_7885301 0.00 ENSRNOT00000035034
RAD50 interactor 1
chr20_-_5441706 0.00 ENSRNOT00000000549
VPS52 GARP complex subunit
chr3_+_172385672 0.00 ENSRNOT00000090989
GNAS complex locus
chr4_+_161685258 0.00 ENSRNOT00000008012
ENSRNOT00000008003
forkhead box M1
chr3_+_11756384 0.00 ENSRNOT00000087762
SH2 domain containing 3C
chr7_-_124317379 0.00 ENSRNOT00000013398
protein kinase C and casein kinase substrate in neurons 2
chr8_+_117574161 0.00 ENSRNOT00000077078
inositol hexakisphosphate kinase 2
chr1_+_16819170 0.00 ENSRNOT00000019734
ENSRNOT00000086756
HBS1-like translational GTPase
chr10_+_88490798 0.00 ENSRNOT00000023872
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_-_157155609 0.00 ENSRNOT00000016330
complement C1s
chr19_+_37305248 0.00 ENSRNOT00000068299
solute carrier family 9 member A5
chr1_+_72425707 0.00 ENSRNOT00000058956
SH3 domain binding kinase family, member 2
chr6_-_25507073 0.00 ENSRNOT00000061176
phospholipase B1
chr1_-_80580662 0.00 ENSRNOT00000024779
cleft lip and palate associated transmembrane protein 1
chr16_+_6970342 0.00 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr2_+_250600823 0.00 ENSRNOT00000083750
selenoprotein 15
chr14_+_21972274 0.00 ENSRNOT00000060265
casein beta
chr7_-_144269486 0.00 ENSRNOT00000090051
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_-_116532169 0.00 ENSRNOT00000085364
RNA binding motif protein 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957) response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.0 0.1 GO:0021550 neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0097324 Kit signaling pathway(GO:0038109) melanocyte migration(GO:0097324) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.0 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)