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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Gli2
Z-value: 0.39
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Transcription factors associated with Gli2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gli2 | rn6_v1_chr13_-_35048444_35048444 | 0.60 | 2.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_12658065 Show fit | 0.25 |
ENSRNOT00000072951
ENSRNOT00000001679 |
collagen type VI alpha 1 chain |
|
| chr7_-_70552897 Show fit | 0.18 |
ENSRNOT00000080594
|
kinesin family member 5A |
|
| chr1_+_141767940 Show fit | 0.14 |
ENSRNOT00000064034
|
zinc finger protein 710 |
|
| chr3_+_56125924 Show fit | 0.14 |
ENSRNOT00000011380
|
ubiquitin protein ligase E3 component n-recognin 3 |
|
| chr8_+_116332796 Show fit | 0.13 |
ENSRNOT00000021408
|
hyaluronoglucosaminidase 1 |
|
| chr10_-_27179254 Show fit | 0.12 |
ENSRNOT00000004619
|
gamma-aminobutyric acid type A receptor gamma 2 subunit |
|
| chr8_-_116531784 Show fit | 0.12 |
ENSRNOT00000024529
|
RNA binding motif protein 5 |
|
| chrX_-_20070537 Show fit | 0.12 |
ENSRNOT00000093602
ENSRNOT00000003397 |
G protein nucleolar 3 like |
|
| chr6_+_58468155 Show fit | 0.12 |
ENSRNOT00000091263
|
ets variant 1 |
|
| chr6_+_132702448 Show fit | 0.11 |
ENSRNOT00000005743
|
YY1 transcription factor |
Network of associatons between targets according to the STRING database.
First level regulatory network of Gli2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 0.2 | GO:0098971 | anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) |
| 0.0 | 0.2 | GO:0030070 | insulin processing(GO:0030070) |
| 0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.0 | 0.1 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.0 | 0.1 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.0 | 0.1 | GO:0034696 | response to prostaglandin F(GO:0034696) |
| 0.0 | 0.1 | GO:2000537 | immunoglobulin production in mucosal tissue(GO:0002426) T-helper 1 cell activation(GO:0035711) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) regulation of thymocyte migration(GO:2000410) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.0 | 0.1 | GO:0021627 | muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629) |
| 0.0 | 0.1 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.1 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.2 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.1 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 0.1 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.0 | 0.1 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.0 | 0.1 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.0 | GO:0000829 | inositol heptakisphosphate kinase activity(GO:0000829) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |