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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Gli1

Z-value: 0.27

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Transcription factors associated with Gli1

Gene Symbol Gene ID Gene Info
ENSRNOG00000025120 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli1rn6_v1_chr7_-_70630338_70630338-0.355.6e-01Click!

Activity profile of Gli1 motif

Sorted Z-values of Gli1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_216080287 0.16 ENSRNOT00000027682
tyrosine hydroxylase
chr10_-_90312386 0.12 ENSRNOT00000028445
solute carrier family 4 member 1
chr6_-_27190126 0.11 ENSRNOT00000068412
ENSRNOT00000013107
potassium two pore domain channel subfamily K member 3
chr6_+_137997335 0.08 ENSRNOT00000006872
transmembrane protein 121
chr16_-_82439441 0.06 ENSRNOT00000040315

chr1_-_80221417 0.06 ENSRNOT00000072149
FosB proto-oncogene, AP-1 transcription factor subunit
chr3_+_154043873 0.06 ENSRNOT00000072502
ENSRNOT00000034166
neuronatin
chr12_+_47074200 0.05 ENSRNOT00000014910
dynein light chain LC8-type 1
chr18_-_28454756 0.05 ENSRNOT00000040091
spermatogenesis associated 24
chr4_+_24617008 0.05 ENSRNOT00000086607
EWS RNA-binding protein 1
chr1_-_80689171 0.04 ENSRNOT00000045574
basal cell adhesion molecule (Lutheran blood group)
chr4_+_55715744 0.04 ENSRNOT00000010429
ADP-ribosylation factor 5
chr2_-_46544457 0.04 ENSRNOT00000015680
follistatin
chr7_-_12326392 0.04 ENSRNOT00000039728
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr19_-_37938857 0.04 ENSRNOT00000026730
solute carrier family 12 member 4
chr3_+_148579920 0.04 ENSRNOT00000012432
HCK proto-oncogene, Src family tyrosine kinase
chr5_+_131380297 0.04 ENSRNOT00000010548
ATP/GTP binding protein-like 4
chr5_-_17061361 0.04 ENSRNOT00000089318
proenkephalin
chr1_-_84812486 0.04 ENSRNOT00000078369

chr5_-_60871705 0.04 ENSRNOT00000016582
exosome component 3
chr10_+_38889370 0.03 ENSRNOT00000091236
septin 8
chr5_+_63781801 0.03 ENSRNOT00000008302
nuclear receptor subfamily 4, group A, member 3
chr7_-_2712723 0.03 ENSRNOT00000004363
interleukin 23 subunit alpha
chr4_-_170932618 0.03 ENSRNOT00000007779
Rho GDP dissociation inhibitor beta
chr19_+_46761570 0.03 ENSRNOT00000058779
WW domain-containing oxidoreductase
chr7_-_96464049 0.02 ENSRNOT00000006517
hyaluronan synthase 2
chr7_+_121480723 0.02 ENSRNOT00000065304
activating transcription factor 4
chr5_+_172273459 0.02 ENSRNOT00000017957
membrane metallo-endopeptidase-like 1
chr10_+_86860685 0.02 ENSRNOT00000084644
retinoic acid receptor, alpha
chr10_+_59566223 0.02 ENSRNOT00000024068
ENSRNOT00000088245
purinergic receptor P2X 1
chr4_-_117631716 0.02 ENSRNOT00000057475
RNA/RNP complex-1-interacting phosphatase
chr8_-_55177818 0.02 ENSRNOT00000013960
heat shock protein family B (small) member 2
chr1_+_207508414 0.02 ENSRNOT00000054896
neuropeptide S
chr18_+_58270410 0.02 ENSRNOT00000067554
APC down-regulated 1
chr10_+_65448950 0.02 ENSRNOT00000082348
ENSRNOT00000037016
RAB34, member RAS oncogene family
chr16_+_7212488 0.02 ENSRNOT00000024840
5'-nucleotidase domain containing 2
chr3_-_11102515 0.02 ENSRNOT00000035580
family with sequence similarity 78, member A
chr18_+_57011575 0.02 ENSRNOT00000026679
interleukin 17B
chrX_-_72370044 0.02 ENSRNOT00000004224
histone deacetylase 8
chr16_+_54332660 0.02 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr1_+_84304228 0.02 ENSRNOT00000024771
periaxin
chr5_+_135962911 0.02 ENSRNOT00000087353
patched 2
chr8_+_65686648 0.02 ENSRNOT00000017233
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr18_-_19275273 0.02 ENSRNOT00000041707
lateral signaling target protein 2 homolog
chr11_+_47061354 0.02 ENSRNOT00000039997
PEST proteolytic signal containing nuclear protein
chr2_+_225645568 0.02 ENSRNOT00000017878
ATP binding cassette subfamily A member 4
chr1_-_261986759 0.02 ENSRNOT00000021257
pyridine nucleotide-disulphide oxidoreductase domain 2
chr5_+_126164674 0.02 ENSRNOT00000009402
24-dehydrocholesterol reductase
chr17_-_84614228 0.02 ENSRNOT00000043042

chr3_+_152752091 0.01 ENSRNOT00000037177
DLG associated protein 4
chrX_-_115426083 0.01 ENSRNOT00000014756

chr3_-_148312791 0.01 ENSRNOT00000091419
Bcl2-like 1
chr17_-_1093873 0.01 ENSRNOT00000086130
patched 1
chr10_-_108321644 0.01 ENSRNOT00000075171
TBC1 domain family, member 16
chr2_+_198040536 0.01 ENSRNOT00000028744
acidic nuclear phosphoprotein 32 family member E
chr3_-_147481073 0.01 ENSRNOT00000084722
family with sequence similarity 110, member A
chr1_+_192025710 0.01 ENSRNOT00000077457
ubiquitin family domain containing 1
chr10_-_88122233 0.01 ENSRNOT00000083895
ENSRNOT00000005285
keratin 14
chr7_+_14643704 0.01 ENSRNOT00000044642

chr4_+_61924013 0.01 ENSRNOT00000090717
bisphosphoglycerate mutase
chrX_+_15049462 0.01 ENSRNOT00000007015
emopamil binding protein (sterol isomerase)
chr5_+_140923914 0.01 ENSRNOT00000020929
hes-related family bHLH transcription factor with YRPW motif-like
chr9_-_10734073 0.01 ENSRNOT00000071199
lysine demethylase 4B
chr2_+_12102487 0.01 ENSRNOT00000089209
ENSRNOT00000072155
centrin-3-like
chr10_-_13580821 0.01 ENSRNOT00000009735
netrin 3
chr1_-_210739600 0.01 ENSRNOT00000031734
transcription elongation regulator 1-like
chr1_+_144070754 0.01 ENSRNOT00000079989
SH3 domain-containing GRB2-like 3
chr10_+_86669233 0.01 ENSRNOT00000012340
thyroid hormone receptor alpha
chr5_+_126698582 0.01 ENSRNOT00000012427
CUB domain containing protein 2
chr1_-_220467159 0.01 ENSRNOT00000075365
transmembrane protein 151A
chr1_+_113034227 0.01 ENSRNOT00000081831
ENSRNOT00000077877
ENSRNOT00000077594
gamma-aminobutyric acid type A receptor beta 3 subunit
chr20_-_10968432 0.01 ENSRNOT00000001593
cystatin B
chr15_+_34155504 0.01 ENSRNOT00000024782
dehydrogenase/reductase 4
chr5_+_133620706 0.01 ENSRNOT00000053202
predicted gene 12830
chr1_-_170397191 0.01 ENSRNOT00000090181
amyloid beta precursor protein binding family B member 1
chr5_-_6186329 0.01 ENSRNOT00000012610
sulfatase 1
chr1_+_72636959 0.01 ENSRNOT00000023489
interleukin 11
chr1_+_192025357 0.00 ENSRNOT00000025072
ubiquitin family domain containing 1
chr18_+_79406381 0.00 ENSRNOT00000022303
ENSRNOT00000058295
ENSRNOT00000058296
ENSRNOT00000022280
myelin basic protein
chr10_+_20320878 0.00 ENSRNOT00000009714
slit guidance ligand 3
chr8_-_23084879 0.00 ENSRNOT00000018874
zinc finger protein 653
chr5_-_65073012 0.00 ENSRNOT00000007957
glutamate ionotropic receptor NMDA type subunit 3A
chr7_+_133089166 0.00 ENSRNOT00000085280

chr16_+_61758917 0.00 ENSRNOT00000084858
leptin receptor overlapping transcript-like 1
chr8_-_59239954 0.00 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr1_-_91855983 0.00 ENSRNOT00000017172
regulator of G protein signaling 9 binding protein
chr2_+_248715281 0.00 ENSRNOT00000089648
general transcription factor IIB
chr19_+_37330930 0.00 ENSRNOT00000022439
pleckstrin homology and RhoGEF domain containing G4
chr19_+_53055745 0.00 ENSRNOT00000074430
forkhead box L1
chr7_+_141326950 0.00 ENSRNOT00000084075
acid sensing ion channel subunit 1
chr6_+_96871625 0.00 ENSRNOT00000012361
small nuclear RNA activating complex, polypeptide 1
chr3_+_8450612 0.00 ENSRNOT00000040457
outer dense fiber of sperm tails 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0010037 response to carbon dioxide(GO:0010037)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.0 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.0 0.0 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.0 0.0 GO:0051140 positive regulation of memory T cell differentiation(GO:0043382) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) regulation of T-helper 17 cell lineage commitment(GO:2000328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)