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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Gcm2

Z-value: 0.86

Motif logo

Transcription factors associated with Gcm2

Gene Symbol Gene ID Gene Info
ENSRNOG00000015008 glial cells missing homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm2rn6_v1_chr17_+_21490402_214904020.019.8e-01Click!

Activity profile of Gcm2 motif

Sorted Z-values of Gcm2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_47551935 0.79 ENSRNOT00000056932
RGD1560398
chr4_+_438668 0.75 ENSRNOT00000008951
engrailed homeobox 2
chr14_-_78707861 0.66 ENSRNOT00000091927
protein phosphatase 2, regulatory subunit B, gamma
chr1_+_274245184 0.57 ENSRNOT00000018889
dual specificity phosphatase 5
chr9_+_10305470 0.53 ENSRNOT00000072592
neurturin
chr10_-_63952726 0.53 ENSRNOT00000090461
double C2 domain beta
chr7_+_11152038 0.52 ENSRNOT00000006168
nuclear factor I/C
chr6_-_99783047 0.52 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr10_-_15166457 0.50 ENSRNOT00000026676
meteorin, glial cell differentiation regulator
chr7_+_11215328 0.47 ENSRNOT00000061194
hypothetical protein LOC690617
chr19_+_41482728 0.43 ENSRNOT00000022943
calbindin 2
chr4_+_78263866 0.41 ENSRNOT00000033807
expressed sequence AI854703
chr8_-_6203515 0.39 ENSRNOT00000087278
ENSRNOT00000031189
ENSRNOT00000008074
ENSRNOT00000085285
ENSRNOT00000007866
yes-associated protein 1
chr16_+_73755539 0.38 ENSRNOT00000088219
tissue-type plasminogen activator-like
chr6_+_33885495 0.37 ENSRNOT00000086633
syndecan 1
chr7_-_123088819 0.35 ENSRNOT00000056077

chr10_-_85574889 0.35 ENSRNOT00000072274
hypothetical protein LOC691153
chr9_+_17841410 0.33 ENSRNOT00000031706
transmembrane protein 151B
chr10_-_88551056 0.33 ENSRNOT00000032737
zinc finger protein 385C
chr5_+_120250616 0.32 ENSRNOT00000070967
adenylate kinase 4
chr16_-_71319449 0.32 ENSRNOT00000029284
Fibroblast growth factor receptor 1
chr7_-_107634287 0.30 ENSRNOT00000093672
ENSRNOT00000087116
src-like adaptor
chr10_-_61361250 0.30 ENSRNOT00000092203
RAP1 GTPase activating protein 2
chr14_-_82055290 0.29 ENSRNOT00000058062
RGD1560394
chr7_-_13751271 0.29 ENSRNOT00000009931
solute carrier family 1 member 6
chr3_+_175144495 0.29 ENSRNOT00000082601
ENSRNOT00000088026
cadherin 4
chr5_-_21345805 0.28 ENSRNOT00000081296
ENSRNOT00000007802
carbonic anhydrase 8
chr3_-_114307250 0.28 ENSRNOT00000064592
Src homology 2 domain containing F
chr8_-_98738446 0.28 ENSRNOT00000019860
Zic family member 1
chr8_-_45215974 0.27 ENSRNOT00000010792
cytotoxic and regulatory T cell molecule
chr3_-_11382004 0.27 ENSRNOT00000047921
ENSRNOT00000064039
dynamin 1
chr10_+_109446444 0.25 ENSRNOT00000066736
BAH domain and coiled-coil containing 1
chrX_-_39956841 0.25 ENSRNOT00000050708
kelch-like family member 34
chr10_+_55940533 0.24 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr5_-_138697641 0.24 ENSRNOT00000012062
guanylate cyclase activator 2B
chr1_+_87650207 0.24 ENSRNOT00000077161
zinc finger protein 84
chr5_-_153625869 0.24 ENSRNOT00000024464
chloride intracellular channel 4
chr8_+_62723788 0.24 ENSRNOT00000010620
semaphorin 7A (John Milton Hagen blood group)
chr10_-_53037816 0.23 ENSRNOT00000057509
shisa family member 6
chr7_+_121311024 0.23 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr15_-_4035064 0.22 ENSRNOT00000012300
fucosyltransferase 11
chr15_+_37790141 0.22 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr4_-_66336901 0.22 ENSRNOT00000035326

chr2_-_77632628 0.22 ENSRNOT00000073915
brain abundant, membrane attached signal protein 1
chr10_+_86399827 0.22 ENSRNOT00000009299
growth factor receptor bound protein 7
chr12_-_38782010 0.22 ENSRNOT00000001813
WD repeat domain 66
chr15_-_56970365 0.22 ENSRNOT00000047192
leucine rich repeats and calponin homology domain containing 1
chr8_-_116893057 0.22 ENSRNOT00000082113
bassoon (presynaptic cytomatrix protein)
chr12_-_40227297 0.21 ENSRNOT00000030600
family with sequence similarity 109, member A
chr3_+_161121697 0.21 ENSRNOT00000036020
WAP four-disulfide core domain 10A
chr10_+_40553180 0.21 ENSRNOT00000087763
solute carrier family 36 member 1
chr6_+_132219088 0.21 ENSRNOT00000034883
HHIP-like 1
chr5_-_82168347 0.20 ENSRNOT00000084959
ENSRNOT00000084147
astrotactin 2
chr10_-_40953651 0.20 ENSRNOT00000063889
glycine receptor, alpha 1
chr9_-_38495126 0.20 ENSRNOT00000016933
ENSRNOT00000090385
RAB23, member RAS oncogene family
chr14_-_80680738 0.20 ENSRNOT00000077706
smoothelin-like
chr4_+_148139528 0.20 ENSRNOT00000092594
ENSRNOT00000015620
ENSRNOT00000092613
WASH complex subunit 2C
chr18_-_80865584 0.20 ENSRNOT00000021750
teashirt zinc finger homeobox 1
chr8_+_12160067 0.20 ENSRNOT00000036338
mastermind-like transcriptional coactivator 2
chr3_-_153188915 0.20 ENSRNOT00000079893
suppressor of glucose, autophagy associated 1
chr10_+_36098051 0.19 ENSRNOT00000083971
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr3_+_147358858 0.19 ENSRNOT00000012951
R-spondin 4
chr4_-_123713319 0.19 ENSRNOT00000012875
ENSRNOT00000086982
solute carrier family 6 member 6
chr5_+_59080765 0.19 ENSRNOT00000021888
ENSRNOT00000064419
RGP1 homolog, RAB6A GEF complex partner 1
chr10_+_92191718 0.19 ENSRNOT00000006764
ENSRNOT00000032941
corticotropin releasing hormone receptor 1
chr16_-_59366824 0.19 ENSRNOT00000015062
similar to 6430573F11Rik protein
chr18_-_31343797 0.19 ENSRNOT00000081850
protocadherin 1
chr10_-_103848035 0.18 ENSRNOT00000029001
fatty acid desaturase 6
chr4_-_147163467 0.18 ENSRNOT00000010748
tissue inhibitor of metalloproteinase 4
chr8_+_130762674 0.18 ENSRNOT00000005422
SNF related kinase
chr19_-_25288335 0.18 ENSRNOT00000050214
nanos C2HC-type zinc finger 3
chrX_-_73778595 0.18 ENSRNOT00000076081
ENSRNOT00000075926
ENSRNOT00000003782
ring finger protein, LIM domain interacting
chr14_+_16491573 0.18 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chrX_+_18998532 0.18 ENSRNOT00000004213

chr19_+_24800072 0.18 ENSRNOT00000005470
prostaglandin E receptor 1
chr3_-_72289310 0.18 ENSRNOT00000038250
reticulon 4 receptor-like 2
chr6_-_102196138 0.18 ENSRNOT00000014132
transmembrane protein 229B
chr19_-_59502161 0.17 ENSRNOT00000075292
interferon regulatory factor 2 binding protein 2
chr1_-_78212350 0.17 ENSRNOT00000071098
InaF-motif containing 1
chr1_+_214927172 0.17 ENSRNOT00000027134
BR serine/threonine kinase 2
chr3_+_56766475 0.17 ENSRNOT00000078819
Sp5 transcription factor
chr7_-_117151256 0.17 ENSRNOT00000078846
nuclear receptor binding protein 2
chrX_+_33895769 0.17 ENSRNOT00000085993
ENSRNOT00000079365
RALBP1 associated Eps domain containing protein 2
chr1_-_201906286 0.17 ENSRNOT00000064511
ENSRNOT00000036625
similar to RIKEN cDNA 1700063I17
chr1_-_101388125 0.17 ENSRNOT00000028176
ENSRNOT00000049957
small nuclear ribonucleoprotein U1 subunit 70
chr10_-_70172739 0.17 ENSRNOT00000010015
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr4_-_145147397 0.16 ENSRNOT00000010347
lipoma HMGIC fusion partner-like 4
chr12_-_2555164 0.16 ENSRNOT00000084460
ENSRNOT00000061821
mitogen activated protein kinase kinase 7
chr17_+_70684134 0.16 ENSRNOT00000025731
ENSRNOT00000068354
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_89539210 0.16 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr6_-_125853461 0.16 ENSRNOT00000007505
ataxin 3
chr6_+_137824213 0.16 ENSRNOT00000056880
phosphofurin acidic cluster sorting protein 2
chr7_-_141307233 0.16 ENSRNOT00000071885
Rac GTPase-activating protein 1
chr12_-_45801842 0.16 ENSRNOT00000078837

chr9_+_40972089 0.16 ENSRNOT00000067928
protein tyrosine phosphatase, non-receptor type 18
chr7_+_130498199 0.16 ENSRNOT00000092684
ENSRNOT00000092431
SH3 and multiple ankyrin repeat domains 3
chr10_-_76166251 0.16 ENSRNOT00000003251
ENSRNOT00000055683
A-kinase anchoring protein 1
chr7_-_101140308 0.16 ENSRNOT00000006279
family with sequence similarity 84, member B
chr4_-_150244372 0.16 ENSRNOT00000047685
ret proto-oncogene
chr11_+_57207656 0.15 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_-_126582034 0.15 ENSRNOT00000010656
ENSRNOT00000080829
inositol-tetrakisphosphate 1-kinase
chr17_-_89881919 0.15 ENSRNOT00000090982
acyl-CoA-binding domain-containing protein 5-like
chr4_+_153774486 0.15 ENSRNOT00000074096
tubulin, alpha 8
chr5_-_150163395 0.15 ENSRNOT00000079935
erythrocyte membrane protein band 4.1
chr3_-_176926722 0.15 ENSRNOT00000020168
zinc finger and BTB domain containing 46
chr7_-_142210738 0.15 ENSRNOT00000006095
POU class 6 homeobox 1
chr1_-_261090437 0.15 ENSRNOT00000072055
FRAT2, WNT signaling pathway regulator
chr3_+_177226417 0.15 ENSRNOT00000031328
opioid related nociceptin receptor 1
chr12_-_35979193 0.15 ENSRNOT00000071104
transmembrane protein 132B
chr1_+_185356975 0.15 ENSRNOT00000086681
pleckstrin homology domain containing A7
chr14_-_82658891 0.15 ENSRNOT00000006841
UV-stimulated scaffold protein A
chr17_+_13516456 0.15 ENSRNOT00000018378
semaphorin 4D
chr14_-_112946875 0.15 ENSRNOT00000081981
coiled-coil domain-containing protein 85A-like
chr9_-_121931564 0.15 ENSRNOT00000056243
thymidylate synthetase
chr20_-_1980101 0.15 ENSRNOT00000084582
ENSRNOT00000085050
ENSRNOT00000082545
ENSRNOT00000088396
gamma-aminobutyric acid type B receptor subunit 1
chr3_+_175408629 0.15 ENSRNOT00000081344
LSM family member 14B
chr3_-_9936352 0.14 ENSRNOT00000011224
ENSRNOT00000042798
formin binding protein 1
chr7_+_11660934 0.14 ENSRNOT00000022336
lamin B2
chr6_+_104291071 0.14 ENSRNOT00000006798
solute carrier family 39, member 9
chr5_+_152613255 0.14 ENSRNOT00000037097
platelet-activating factor acetylhydrolase 2
chr4_-_68597586 0.14 ENSRNOT00000015921
similar to RIKEN cDNA E330009J07 gene
chr10_-_90940118 0.14 ENSRNOT00000093143
elongation factor Tu GTP binding domain containing 2
chr17_-_13393243 0.14 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr10_-_40953467 0.14 ENSRNOT00000092189
glycine receptor, alpha 1
chr1_+_266953139 0.14 ENSRNOT00000054696
neuralized E3 ubiquitin protein ligase 1
chr5_-_137014375 0.14 ENSRNOT00000066165
ENSRNOT00000091866
lysine demethylase 4A
chr12_-_22245100 0.14 ENSRNOT00000001912
GRB10 interacting GYF protein 1
chr16_+_67350539 0.14 ENSRNOT00000085659
ENSRNOT00000015879
unc-5 netrin receptor D
chr12_+_28381982 0.14 ENSRNOT00000076101
Williams-Beuren syndrome chromosome region 17
chr5_-_150994913 0.14 ENSRNOT00000075506
similar to RIKEN cDNA 2900010J23
chr3_-_156777999 0.14 ENSRNOT00000032588
ENSRNOT00000091208
zinc fingers and homeoboxes 3
chr6_+_135610743 0.14 ENSRNOT00000010906
Tnf receptor-associated factor 3
chr5_-_60871705 0.14 ENSRNOT00000016582
exosome component 3
chr1_+_40891597 0.14 ENSRNOT00000026482
A-kinase anchoring protein 12
chr10_+_14035149 0.14 ENSRNOT00000065827
zinc finger protein 598
chr20_+_7431355 0.13 ENSRNOT00000049592
UHRF1 binding protein 1
chr2_+_123734199 0.13 ENSRNOT00000038729
similar to RIKEN cDNA D630029K19
chr9_-_81400987 0.13 ENSRNOT00000035277
tensin 1
chr7_-_127081704 0.13 ENSRNOT00000055893
uncharacterized LOC108351584
chr12_-_10391270 0.13 ENSRNOT00000092340
WAS protein family, member 3
chr15_+_47470863 0.13 ENSRNOT00000072438
similar to Plasma kallikrein precursor (Plasma prekallikrein) (Kininogenin) (Fletcher factor)
chr3_-_110492398 0.13 ENSRNOT00000056450
ankyrin repeat domain 63
chr10_+_15241590 0.13 ENSRNOT00000037372
ENSRNOT00000037381
methyltransferase like 26
chr4_-_156427755 0.13 ENSRNOT00000085675
ENSRNOT00000014030
peroxisomal targeting signal 1 receptor-like
chr16_+_20740826 0.13 ENSRNOT00000038057
CREB regulated transcription coactivator 1
chr17_-_48562838 0.13 ENSRNOT00000017102
ENSRNOT00000084702
amphiphysin
chr9_+_15166118 0.13 ENSRNOT00000020432
MyoD family inhibitor
chr7_-_2353875 0.13 ENSRNOT00000074873
zinc finger protein 36, C3H1 type-like 2-like
chr18_+_73564247 0.13 ENSRNOT00000077679
ENSRNOT00000035317
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_+_144646308 0.13 ENSRNOT00000078337
ENSRNOT00000093407
doublecortin-like kinase 1
chr4_+_77592016 0.13 ENSRNOT00000009054
Zinc finger protein 212
chr7_-_71048383 0.13 ENSRNOT00000005693
G protein-coupled receptor 182
chr2_-_113345577 0.13 ENSRNOT00000034096
fibronectin type III domain containing 3B
chr4_-_157008947 0.13 ENSRNOT00000073341
peroxisomal biogenesis factor 5
chr7_-_11003785 0.13 ENSRNOT00000061279
transducin-like enhancer of split 2
chr3_+_175426752 0.13 ENSRNOT00000085718
SS18L1, nBAF chromatin remodeling complex subunit
chr1_-_261446570 0.13 ENSRNOT00000020182
secreted frizzled-related protein 5
chr3_-_11410732 0.13 ENSRNOT00000034930
similar to Hypothetical UPF0184 protein C9orf16 homolog
chr17_+_77185053 0.13 ENSRNOT00000091561
optineurin
chr10_+_36741434 0.12 ENSRNOT00000064078
collagen type XXIII alpha 1 chain
chr19_-_15840990 0.12 ENSRNOT00000015583
iroquois homeobox 3
chr13_-_70922245 0.12 ENSRNOT00000064860
DExH-box helicase 9
chr10_-_108473377 0.12 ENSRNOT00000070934
N-sulfoglucosamine sulfohydrolase
chr8_+_116094851 0.12 ENSRNOT00000084120
similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr1_+_33910912 0.12 ENSRNOT00000044690
iroquois homeobox 1
chr1_-_87777668 0.12 ENSRNOT00000037288

chr8_+_64489942 0.12 ENSRNOT00000083666
pyruvate kinase, muscle
chr9_-_82699551 0.12 ENSRNOT00000020673
obscurin-like 1
chr4_+_170149029 0.12 ENSRNOT00000073287
histone H2A.J
chr18_-_77317969 0.12 ENSRNOT00000090369
nuclear factor of activated T-cells 1
chr7_+_70364813 0.12 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_-_79282493 0.12 ENSRNOT00000049832
protein tyrosine phosphatase, receptor type, J
chr1_+_78029555 0.12 ENSRNOT00000047289
solute carrier family 8 member A2
chr1_+_81372650 0.12 ENSRNOT00000088829
zinc finger protein 428
chr15_+_23665202 0.12 ENSRNOT00000089226
sterile alpha motif domain containing 4A
chr4_-_126644895 0.12 ENSRNOT00000017384
ENSRNOT00000072624
leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_117126822 0.12 ENSRNOT00000086720
RAB11 family interacting protein 5
chr10_-_64642292 0.12 ENSRNOT00000084670
active BCR-related
chr10_-_29450644 0.12 ENSRNOT00000087937
adrenoceptor alpha 1B
chr6_+_35314444 0.12 ENSRNOT00000005666
odd-skipped related transciption factor 1
chr12_+_40244081 0.12 ENSRNOT00000030583
SH2B adaptor protein 3
chr14_-_35149608 0.12 ENSRNOT00000003050
ENSRNOT00000090654
KIT proto-oncogene receptor tyrosine kinase
chr1_-_262013619 0.12 ENSRNOT00000021278
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr4_-_180505916 0.12 ENSRNOT00000086465

chr1_-_88112683 0.11 ENSRNOT00000090615
sprouty-related, EVH1 domain containing 3
chr8_-_21968415 0.11 ENSRNOT00000067325
ENSRNOT00000064932
DNA methyltransferase 1
chr2_-_88314254 0.11 ENSRNOT00000038546
carbonic anhydrase 13
chr1_-_163129641 0.11 ENSRNOT00000083055
calpain 5
chr9_-_10054359 0.11 ENSRNOT00000072001
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr19_+_41932221 0.11 ENSRNOT00000059225
alanine and glycine-rich protein-like
chr2_-_261402880 0.11 ENSRNOT00000052396
ENSRNOT00000077839
ENSRNOT00000088561
fucose-1-phosphate guanylyltransferase
chr13_+_52667969 0.11 ENSRNOT00000084986
ENSRNOT00000050284
troponin T2, cardiac type
chr12_+_37878653 0.11 ENSRNOT00000091084
phosphatidylinositol transfer protein, membrane-associated 2
chrX_-_19386541 0.11 ENSRNOT00000072722

chr13_-_51076852 0.11 ENSRNOT00000078993
adenosine A1 receptor
chr1_-_125967756 0.11 ENSRNOT00000031488
family with sequence similarity 189, member A1
chr4_+_13405136 0.11 ENSRNOT00000091004
G protein subunit alpha i1
chr7_-_117364322 0.11 ENSRNOT00000080724
5-oxoprolinase (ATP-hydrolysing)
chr3_+_148541909 0.11 ENSRNOT00000012187
CCM2 like scaffolding protein
chr1_+_190666149 0.11 ENSRNOT00000089361
uncharacterized LOC102547219

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048372 ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.4 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.2 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1 0.2 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.1 0.2 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 0.4 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.2 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.2 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.2 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0046078 pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
0.0 0.2 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.0 GO:1905072 cardiac jelly development(GO:1905072)
0.0 0.1 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.0 0.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.3 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0070256 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
0.0 0.2 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0097394 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0032902 nerve growth factor production(GO:0032902)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:1990859 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
0.0 0.1 GO:1900158 regulation of chondrocyte development(GO:0061181) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0050713 PML body organization(GO:0030578) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350) GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:0061744 motor behavior(GO:0061744)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.0 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382) regulation of RNA interference(GO:1900368)
0.0 0.0 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934) protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.0 GO:1901423 response to benzene(GO:1901423)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0072642 negative regulation of B cell differentiation(GO:0045578) type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.0 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.0 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0071847 circadian temperature homeostasis(GO:0060086) TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0021747 cochlear nucleus development(GO:0021747)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.0 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.0 GO:0072248 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.0 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.0 GO:0072054 renal outer medulla development(GO:0072054)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.0 GO:0050893 sensory processing(GO:0050893)
0.0 0.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.0 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.0 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.0 GO:1990743 protein sialylation(GO:1990743)
0.0 0.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0060717 chorion development(GO:0060717)
0.0 0.1 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243) Notch signaling involved in heart development(GO:0061314)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.0 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:1990423 RZZ complex(GO:1990423)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.0 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030977 taurine binding(GO:0030977)
0.1 0.2 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.1 0.2 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0102390 mycophenolic acid acyl-glucuronide esterase activity(GO:0102390)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.1 GO:0015368 calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0001054 RNA polymerase I activity(GO:0001054)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling