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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Gcm1

Z-value: 0.39

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Transcription factors associated with Gcm1

Gene Symbol Gene ID Gene Info
ENSRNOG00000007932 glial cells missing homolog 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm1rn6_v1_chr8_+_85355766_85355766-0.622.6e-01Click!

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_115910522 0.19 ENSRNOT00000076998
ENSRNOT00000067442
activity-regulated cytoskeleton-associated protein
chr14_+_104191517 0.17 ENSRNOT00000006573
sprouty-related, EVH1 domain containing 2
chr7_-_12424367 0.14 ENSRNOT00000060698
midnolin
chr9_+_118586179 0.13 ENSRNOT00000022351
DLG associated protein 1
chr10_+_61685645 0.11 ENSRNOT00000003933
MAX network transcriptional repressor
chr3_+_156642464 0.11 ENSRNOT00000085354
topoisomerase (DNA) I
chr1_-_125967756 0.11 ENSRNOT00000031488
family with sequence similarity 189, member A1
chrX_+_62363757 0.10 ENSRNOT00000091240
aristaless related homeobox
chr3_+_108944141 0.10 ENSRNOT00000034950
family with sequence similarity 98, member B
chr6_+_135610743 0.09 ENSRNOT00000010906
Tnf receptor-associated factor 3
chrX_+_62363953 0.09 ENSRNOT00000083362
aristaless related homeobox
chr13_+_75105615 0.09 ENSRNOT00000076653
tumor protein p53 inducible protein 3
chr7_-_12831675 0.09 ENSRNOT00000011936
fibroblast growth factor 22
chrX_+_55331389 0.09 ENSRNOT00000075300

chr6_-_49324450 0.09 ENSRNOT00000066904
syntrophin, gamma 2
chr8_-_116361343 0.08 ENSRNOT00000066296
semaphorin 3B
chr7_-_122247139 0.08 ENSRNOT00000064515
megakaryoblastic leukemia (translocation) 1
chrX_+_68782872 0.07 ENSRNOT00000075995
StAR-related lipid transfer domain containing 8
chr10_+_102136283 0.07 ENSRNOT00000003735
somatostatin receptor 2
chr15_+_34187223 0.07 ENSRNOT00000024978
copine 6
chr14_-_78377825 0.06 ENSRNOT00000068104

chr3_+_33440191 0.06 ENSRNOT00000034632
ENSRNOT00000092907
methyl-CpG binding domain protein 5
chr8_+_96551245 0.06 ENSRNOT00000039850
BCL2-related protein A1
chr11_-_87158597 0.05 ENSRNOT00000002517
pre-B lymphocyte gene 2
chr2_-_186480278 0.05 ENSRNOT00000031743
kin of IRRE like (Drosophila)
chr5_+_139468546 0.05 ENSRNOT00000013193
schlafen-like 1
chr6_-_147172022 0.05 ENSRNOT00000080675
integrin subunit beta 8
chr3_-_122947075 0.05 ENSRNOT00000082369
PC-esterase domain containing 1A
chr1_-_101131413 0.05 ENSRNOT00000093729
fms-related tyrosine kinase 3 ligand
chr2_+_127459012 0.04 ENSRNOT00000093685
ENSRNOT00000072675
inturned planar cell polarity protein
chr9_+_49479023 0.04 ENSRNOT00000050922
ENSRNOT00000077111
POU class 3 homeobox 3
chr5_-_151397603 0.04 ENSRNOT00000076866
G protein-coupled receptor 3
chr14_-_20953095 0.04 ENSRNOT00000004440
deoxycytidine kinase
chr8_+_7128656 0.04 ENSRNOT00000038313
progesterone receptor
chr9_+_47386626 0.04 ENSRNOT00000021270
solute carrier family 9 member A2
chr1_+_266530477 0.03 ENSRNOT00000054699
cyclin and CBS domain divalent metal cation transport mediator 2
chr13_-_111849653 0.03 ENSRNOT00000006395
digestive organ expansion factor homolog (zebrafish)
chr11_-_86276430 0.03 ENSRNOT00000075164
histone cell cycle regulator
chr6_+_18821815 0.03 ENSRNOT00000062057
myotubularin 1
chr1_-_101131012 0.03 ENSRNOT00000082283
ENSRNOT00000093498
ENSRNOT00000093559
fms-related tyrosine kinase 3 ligand
ribosomal protein L13A
chr2_+_57206613 0.03 ENSRNOT00000082694
ENSRNOT00000046069
nucleoporin 155
chr14_-_104523297 0.03 ENSRNOT00000039523
centrosomal protein 68
chr3_+_122308025 0.03 ENSRNOT00000008071
serine/threonine kinase 35
chrX_+_18998532 0.02 ENSRNOT00000004213

chr15_+_3996328 0.02 ENSRNOT00000088252
N-deacetylase and N-sulfotransferase 2
chr1_-_220165678 0.02 ENSRNOT00000026915
Bardet-Biedl syndrome 1
chr1_+_220423426 0.02 ENSRNOT00000072647
breast cancer metastasis-suppressor 1
chr7_+_117963740 0.02 ENSRNOT00000075405
COMM domain-containing protein 5
chr2_+_243502073 0.02 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_7311807 0.02 ENSRNOT00000012222
ENSRNOT00000089817
ATP binding cassette subfamily B member 8
chr15_+_3996048 0.02 ENSRNOT00000078653
N-deacetylase and N-sulfotransferase 2
chr10_+_1464765 0.01 ENSRNOT00000004217
bifunctional apoptosis regulator
chr5_-_141033511 0.01 ENSRNOT00000045922
bone morphogenetic protein 8a
chr4_-_113764532 0.01 ENSRNOT00000009269
ssemaphorin 4F
chr1_-_201906286 0.01 ENSRNOT00000064511
ENSRNOT00000036625
similar to RIKEN cDNA 1700063I17
chr18_+_3958432 0.01 ENSRNOT00000073509
tetratricopeptide repeat domain 39C
chr19_+_37127508 0.01 ENSRNOT00000019656
core-binding factor, beta subunit
chr6_-_50846965 0.01 ENSRNOT00000087300
solute carrier family 26 member 4
chr20_+_50394650 0.01 ENSRNOT00000076010
ENSRNOT00000077065
ENSRNOT00000073259
popeye domain containing 3
chr1_+_53360157 0.01 ENSRNOT00000017809
ribosomal protein S6 kinase A2
chr5_+_157165341 0.01 ENSRNOT00000087072
phospholipase A2, group IIC
chr1_-_259089632 0.01 ENSRNOT00000020940
ENSRNOT00000091297
aldehyde dehydrogenase 18 family, member A1
chr5_-_153252021 0.01 ENSRNOT00000023221
transmembrane protein 50A
chr1_-_259674425 0.01 ENSRNOT00000091116
delta-1-pyrroline-5-carboxylate synthase
chr10_+_105861743 0.01 ENSRNOT00000064410
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr16_+_81089292 0.01 ENSRNOT00000087192
ENSRNOT00000026150
transcription factor Dp-1
chr7_-_117267402 0.01 ENSRNOT00000088945
plectin
chr12_-_21450204 0.00 ENSRNOT00000065866
zinc finger CW-type PWWP domain protein 1-like
chr19_-_17346808 0.00 ENSRNOT00000017361
RB transcriptional corepressor like 2
chr9_-_85528860 0.00 ENSRNOT00000063834
ENSRNOT00000088963
WD repeat and FYVE domain containing 1
chr6_-_147172813 0.00 ENSRNOT00000066545
integrin subunit beta 8
chr14_-_3389943 0.00 ENSRNOT00000037101
epoxide hydrolase 4
chr2_-_123323170 0.00 ENSRNOT00000021453
Bardet-Biedl syndrome 7
chr1_+_274245184 0.00 ENSRNOT00000018889
dual specificity phosphatase 5
chr10_+_105796680 0.00 ENSRNOT00000000264
major facilitator superfamily domain containing 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)