ISMARA results: Gcm1

Project

GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Gcm1

Z-value: 0.39

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Transcription factors associated with Gcm1

Gene Symbol	Gene ID	Gene Info
Gcm1 NCBI RGD Ensembl	ENSRNOG00000007932	glial cells missing homolog 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Gcm1	rn6_v1_chr8_+_85355766_85355766	-0.62	2.6e-01	Click!

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_-_115910522 Show fit	0.19	ENSRNOT00000076998 ENSRNOT00000067442	Arc NCBI RGD Ensembl Show fit	activity-regulated cytoskeleton-associated protein
chr14_+_104191517 Show fit	0.17	ENSRNOT00000006573	Spred2 NCBI RGD Ensembl Show fit	sprouty-related, EVH1 domain containing 2
chr7_-_12424367 Show fit	0.14	ENSRNOT00000060698	Midn NCBI RGD Ensembl Show fit	midnolin
chr9_+_118586179 Show fit	0.13	ENSRNOT00000022351	Dlgap1 NCBI RGD Ensembl Show fit	DLG associated protein 1
chr10_+_61685645 Show fit	0.11	ENSRNOT00000003933	Mnt NCBI RGD Ensembl Show fit	MAX network transcriptional repressor
chr3_+_156642464 Show fit	0.11	ENSRNOT00000085354	Top1 NCBI RGD Ensembl Show fit	topoisomerase (DNA) I
chr1_-_125967756 Show fit	0.11	ENSRNOT00000031488	Fam189a1 NCBI RGD Ensembl Show fit	family with sequence similarity 189, member A1
chrX_+_62363757 Show fit	0.10	ENSRNOT00000091240	Arx NCBI RGD Ensembl Show fit	aristaless related homeobox
chr3_+_108944141 Show fit	0.10	ENSRNOT00000034950	Fam98b NCBI RGD Ensembl Show fit	family with sequence similarity 98, member B
chr6_+_135610743 Show fit	0.09	ENSRNOT00000010906	Traf3 NCBI RGD Ensembl Show fit	Tnf receptor-associated factor 3

Showing 1 to 10 of 75 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.2	GO:0021759	globus pallidus development(GO:0021759)
0.2	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1	GO:0070842	aggresome assembly(GO:0070842)
0.1	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.1	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)

Showing 1 to 10 of 11 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	GO:0097109	neuroligin family protein binding(GO:0097109)

Showing 1 to 6 of 6 entries

Results for Gcm1

Z-value: 0.39

Motif logo

Transcription factors associated with Gcm1

Activity-expression correlation:

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: