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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Gata4

Z-value: 0.23

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Transcription factors associated with Gata4

Gene Symbol Gene ID Gene Info
ENSRNOG00000010708 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata4rn6_v1_chr15_-_46432965_464329650.484.1e-01Click!

Activity profile of Gata4 motif

Sorted Z-values of Gata4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_50381244 0.13 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr17_-_22143324 0.10 ENSRNOT00000019361
endothelin 1
chr1_+_279798187 0.10 ENSRNOT00000024065
pancreatic lipase
chr9_-_82146874 0.10 ENSRNOT00000024190
FEV, ETS transcription factor
chr1_+_72882806 0.10 ENSRNOT00000024640
troponin I3, cardiac type
chr1_-_261446570 0.10 ENSRNOT00000020182
secreted frizzled-related protein 5
chr1_-_164205222 0.06 ENSRNOT00000035774
monoacylglycerol O-acyltransferase 2
chr10_+_103874383 0.05 ENSRNOT00000038935
otopetrin 2
chr8_+_50525091 0.04 ENSRNOT00000074357
apolipoprotein A1
chr15_+_67555835 0.04 ENSRNOT00000045882
protocadherin 17
chr3_+_160852164 0.04 ENSRNOT00000019127
recombination signal binding protein for immunoglobulin kappa J region-like
chr8_-_33661049 0.04 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr18_-_16542165 0.04 ENSRNOT00000079381
solute carrier family 39 member 6
chrX_+_112270986 0.04 ENSRNOT00000091441
ENSRNOT00000082652
V-set and immunoglobulin domain containing 1
chr5_+_138685624 0.04 ENSRNOT00000011867
guanylate cyclase activator 2A
chr1_+_175445088 0.04 ENSRNOT00000036718
adrenomedullin
chr13_-_53870428 0.03 ENSRNOT00000000812
nuclear receptor subfamily 5, group A, member 2
chr19_-_14945302 0.03 ENSRNOT00000079391

chr8_-_117820413 0.02 ENSRNOT00000075819
translation machinery associated 7 homolog
chr4_-_181477281 0.02 ENSRNOT00000055463
MANSC domain containing 4
chrX_-_78496847 0.02 ENSRNOT00000003265
integral membrane protein 2A
chr10_-_15610826 0.02 ENSRNOT00000027851
hemoglobin subunit zeta
chr6_+_50725085 0.02 ENSRNOT00000009473
solute carrier family 26 member 3
chr20_-_2191640 0.02 ENSRNOT00000001016
tripartite motif-containing 10
chr4_+_119225040 0.02 ENSRNOT00000012365
bone morphogenetic protein 10
chrX_-_13601069 0.02 ENSRNOT00000004686
ornithine carbamoyltransferase
chr10_-_87232723 0.02 ENSRNOT00000015150
keratin 25
chr15_-_61772516 0.02 ENSRNOT00000015605
ENSRNOT00000093399
WW domain binding protein 4
chr19_-_10450186 0.02 ENSRNOT00000088048
adhesion G protein-coupled receptor G1
chr11_-_60679555 0.02 ENSRNOT00000059735
coiled-coil domain containing 80
chr3_+_79918969 0.02 ENSRNOT00000016306
Spi-1 proto-oncogene
chr11_-_33003021 0.02 ENSRNOT00000084134
runt-related transcription factor 1
chr1_-_226732736 0.02 ENSRNOT00000072343
pepsin F-like
chr4_+_163162211 0.02 ENSRNOT00000082537
C-type lectin domain family 1, member B
chr6_+_22696397 0.02 ENSRNOT00000011630
anaplastic lymphoma receptor tyrosine kinase
chr2_+_116970344 0.02 ENSRNOT00000039603
EGF-like and EMI domain containing 1
chr11_-_35749464 0.02 ENSRNOT00000078818
ENSRNOT00000078425
ERG, ETS transcription factor
chr8_+_22047697 0.02 ENSRNOT00000067741
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr3_-_112985318 0.02 ENSRNOT00000015556
erythrocyte membrane protein band 4.2
chr2_+_42726809 0.02 ENSRNOT00000036860

chr9_+_95256627 0.02 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr7_+_11490852 0.02 ENSRNOT00000044484
cAMP responsive element binding protein 3-like 3
chr5_+_133864798 0.01 ENSRNOT00000091977
TAL bHLH transcription factor 1, erythroid differentiation factor
chr6_+_137164535 0.01 ENSRNOT00000018225
inverted formin, FH2 and WH2 domain containing
chr5_-_28130803 0.01 ENSRNOT00000093186
solute carrier family 26 member 7
chr6_+_7961413 0.01 ENSRNOT00000007638
ENSRNOT00000061871
ATP binding cassette subfamily G member 8
chr5_+_154077944 0.01 ENSRNOT00000031512
interleukin 22 receptor subunit alpha 1
chr11_-_64952687 0.01 ENSRNOT00000087892
popeye domain containing 2
chr5_+_14890408 0.01 ENSRNOT00000033116
SRY box 17
chr2_-_60657712 0.01 ENSRNOT00000040348
retinoic acid induced 14
chr3_+_159936856 0.01 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chrX_+_83678339 0.01 ENSRNOT00000005997
apolipoprotein O-like
chr2_+_189423559 0.01 ENSRNOT00000029076
tropomyosin 3
chr13_+_48513008 0.01 ENSRNOT00000009742
solute carrier family 26 member 9
chr16_+_49266903 0.01 ENSRNOT00000014704
solute carrier family 25 member 4
chr15_+_33632416 0.01 ENSRNOT00000068212

chr17_-_21677477 0.01 ENSRNOT00000035448
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr19_-_25166528 0.01 ENSRNOT00000007775
relaxin 3
chr1_+_17602281 0.01 ENSRNOT00000075461
jouberin-like
chr10_-_90415070 0.01 ENSRNOT00000055179
integrin subunit alpha 2b
chr3_+_55910177 0.01 ENSRNOT00000009969
kelch-like family member 41
chr6_-_26385761 0.01 ENSRNOT00000073228
glucokinase regulator
chr3_-_2453933 0.01 ENSRNOT00000014060
solute carrier family 34 member 3
chr2_-_77784522 0.01 ENSRNOT00000030328
similar to RIKEN cDNA 0610040D20
chr17_-_84247038 0.01 ENSRNOT00000068553
nebulette
chr17_-_21705773 0.01 ENSRNOT00000078010
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_-_259382765 0.01 ENSRNOT00000091407
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr8_-_48672732 0.01 ENSRNOT00000079275
hydroxymethylbilane synthase
chr3_-_93216495 0.01 ENSRNOT00000010580
ets homologous factor
chr5_-_28131133 0.01 ENSRNOT00000067331
solute carrier family 26 member 7
chr10_+_70262361 0.01 ENSRNOT00000064625
ENSRNOT00000076973
unc-45 myosin chaperone B
chr2_-_192027225 0.01 ENSRNOT00000016430
proline rich 9
chr6_-_23291568 0.01 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr6_-_132797675 0.01 ENSRNOT00000006128
tryptophanyl-tRNA synthetase
chr19_-_38344845 0.00 ENSRNOT00000072666

chrX_-_104932508 0.00 ENSRNOT00000075325
NADPH oxidase 1
chr11_+_80736576 0.00 ENSRNOT00000047678
mannan-binding lectin serine peptidase 1
chr16_+_50022998 0.00 ENSRNOT00000087986
toll-like receptor 3
chr7_+_60099120 0.00 ENSRNOT00000007338
leucine-rich repeat-containing protein 10-like
chr4_-_163261958 0.00 ENSRNOT00000086390
oxidized low density lipoprotein (lectin-like) receptor 1
chr20_+_7718282 0.00 ENSRNOT00000000593
signal peptide, CUB domain and EGF like domain containing 3
chr2_+_212257225 0.00 ENSRNOT00000077883
vav guanine nucleotide exchange factor 3
chrX_+_20351486 0.00 ENSRNOT00000093675
ENSRNOT00000047444
WNK lysine deficient protein kinase 3
chrX_-_119162518 0.00 ENSRNOT00000073176
ubiquitin-conjugating enzyme E2 W
chr1_-_85220237 0.00 ENSRNOT00000026907
syncollin
chr14_-_45165207 0.00 ENSRNOT00000002960
Kruppel like factor 3
chr20_-_27657983 0.00 ENSRNOT00000057313
family with sequence similarity 26, member E
chr6_-_7961207 0.00 ENSRNOT00000007174
ATP binding cassette subfamily G member 5
chr15_-_11812485 0.00 ENSRNOT00000030991
ENSRNOT00000007795
NIMA-related kinase 10
chr2_+_147496229 0.00 ENSRNOT00000022105
transmembrane 4 L six family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
0.0 0.1 GO:2000041 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones