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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Foxc1

Z-value: 0.36

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Transcription factors associated with Foxc1

Gene Symbol Gene ID Gene Info
ENSRNOG00000017800 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxc1rn6_v1_chr17_-_33951484_339514840.424.8e-01Click!

Activity profile of Foxc1 motif

Sorted Z-values of Foxc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_74485139 0.13 ENSRNOT00000022598
solute carrier family 14 member 1
chr5_+_118574801 0.12 ENSRNOT00000035949
ubiquitin-conjugating enzyme E2U (putative)
chr5_-_105579959 0.10 ENSRNOT00000010827
solute carrier family 24 member 2
chr5_+_76092287 0.10 ENSRNOT00000020207
zinc finger protein 483
chr2_-_149444548 0.10 ENSRNOT00000018600
purinergic receptor P2Y12
chr14_+_71533063 0.09 ENSRNOT00000004231
prominin 1
chr7_-_49250953 0.08 ENSRNOT00000066975
ENSRNOT00000082141
acyl-CoA synthetase short-chain family member 3
chr12_-_5773036 0.08 ENSRNOT00000041365
FRY microtubule binding protein
chr17_-_77261731 0.08 ENSRNOT00000066850
upper zone of growth plate and cartilage matrix associated
chr2_+_95077577 0.08 ENSRNOT00000046368
mitochondrial ribosomal protein S28
chr7_-_113937941 0.08 ENSRNOT00000012408
potassium two pore domain channel subfamily K member 9
chr18_+_56379890 0.08 ENSRNOT00000078764
platelet derived growth factor receptor beta
chr4_+_158243086 0.08 ENSRNOT00000032112
anoctamin 2
chr9_-_94495333 0.06 ENSRNOT00000021507
potassium voltage-gated channel subfamily J member 13
chr15_-_83494423 0.06 ENSRNOT00000037588
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
chr6_+_99402360 0.06 ENSRNOT00000078498
zinc finger and BTB domain containing 1
chr3_+_79823945 0.06 ENSRNOT00000014484
CUGBP, Elav-like family member 1
chr17_+_76532611 0.06 ENSRNOT00000024099
calcium/calmodulin-dependent protein kinase ID
chr6_+_64252970 0.06 ENSRNOT00000093700
patatin-like phospholipase domain containing 8
chr1_-_236729412 0.06 ENSRNOT00000054794
prune homolog 2
chr10_-_38969501 0.06 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr13_-_103080920 0.06 ENSRNOT00000034990

chr3_+_60024013 0.05 ENSRNOT00000025255
secernin 3
chr3_-_123849788 0.05 ENSRNOT00000028869
ring finger protein 24
chr13_-_35668968 0.05 ENSRNOT00000042862
ENSRNOT00000003428
erythrocyte membrane protein band 4.1 like 5
chr1_+_27476375 0.05 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr1_+_141120166 0.05 ENSRNOT00000050759
Fanconi anemia, complementation group I
chr7_+_112057030 0.04 ENSRNOT00000035216

chr15_-_61648267 0.04 ENSRNOT00000071805
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr2_-_258997138 0.04 ENSRNOT00000045020
ENSRNOT00000042256
adhesion G protein-coupled receptor L2
chr6_+_64297888 0.04 ENSRNOT00000050222
ENSRNOT00000083088
ENSRNOT00000093147
neuronal cell adhesion molecule
chr3_+_176865156 0.04 ENSRNOT00000019084
zinc finger CCCH-type and G-patch domain containing
chr2_+_84678948 0.04 ENSRNOT00000046325
family with sequence similarity 173, member B
chr3_-_162579201 0.04 ENSRNOT00000068328
zinc finger, MYND-type containing 8
chr3_+_62648447 0.04 ENSRNOT00000002111
alkylglycerone phosphate synthase
chr4_-_165456677 0.04 ENSRNOT00000082207
killer cell lectin-like receptor, subfamily A, member 2
chr14_-_5428757 0.04 ENSRNOT00000002897
leucine rich repeat containing 8 family, member B
chr1_+_215610368 0.04 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr17_-_53688966 0.04 ENSRNOT00000078643
AT-rich interactive domain-containing protein 4B-like
chr11_+_44001579 0.03 ENSRNOT00000002258
G protein-coupled receptor 15
chrX_+_88298266 0.03 ENSRNOT00000041508

chr7_+_130308532 0.03 ENSRNOT00000011941
myo-inositol oxygenase
chr8_-_49308806 0.03 ENSRNOT00000047291
CD3e molecule
chr2_-_30458542 0.03 ENSRNOT00000072926
NLR family, apoptosis inhibitory protein 6
chr6_+_106052212 0.03 ENSRNOT00000010626
signal-induced proliferation-associated 1 like 1
chr11_-_64952687 0.03 ENSRNOT00000087892
popeye domain containing 2
chr13_-_70980913 0.03 ENSRNOT00000003713
N-acetylneuraminate pyruvate lyase
chr16_-_79973735 0.03 ENSRNOT00000057845
ENSRNOT00000086896
DLG associated protein 2
chr1_-_44615760 0.03 ENSRNOT00000022148
NADPH oxidase 3
chr16_-_32439421 0.03 ENSRNOT00000043100
NIMA-related kinase 1
chr3_-_112876773 0.03 ENSRNOT00000015086
ubiquitin protein ligase E3 component n-recognin 1
chr3_+_8802852 0.03 ENSRNOT00000033934
leucine rich repeat containing 8 family, member A
chr2_-_178616719 0.03 ENSRNOT00000078610
transmembrane protein 144
chr4_-_66955732 0.03 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr8_+_132828091 0.02 ENSRNOT00000008269
C-C motif chemokine receptor 9
chr13_-_111972603 0.02 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr11_+_61748883 0.02 ENSRNOT00000093552
queuine tRNA-ribosyltransferase accessory subunit 2
chr1_-_81127059 0.02 ENSRNOT00000026252
zinc finger protein 94
chr1_+_154131926 0.02 ENSRNOT00000035257
ferritin light chain 1-like
chr1_-_253000760 0.02 ENSRNOT00000030024
solute carrier family 16, member 12
chr5_-_50138475 0.02 ENSRNOT00000011969
solute carrier family 35 member A1
chr1_+_88885937 0.02 ENSRNOT00000029719
NFKB inhibitor delta
chr1_+_215609645 0.02 ENSRNOT00000076140
ENSRNOT00000027487
troponin I2, fast skeletal type
chr9_-_81772851 0.02 ENSRNOT00000032719
ubiquitin specific peptidase 37
chr10_-_84698886 0.02 ENSRNOT00000067542
nuclear factor, erythroid 2-like 1
chr14_+_81858737 0.02 ENSRNOT00000029784
ENSRNOT00000058068
ENSRNOT00000058067
DNA polymerase nu
chr20_+_2501252 0.02 ENSRNOT00000079307
ENSRNOT00000084559
tripartite motif-containing 39
chr16_+_35573058 0.02 ENSRNOT00000059580
polypeptide N-acetylgalactosaminyltransferase-like 6
chr19_+_52086325 0.02 ENSRNOT00000020341
N-terminal EF-hand calcium binding protein 2
chr5_+_117583502 0.02 ENSRNOT00000010933
ubiquitin specific peptidase 1
chr3_+_172719432 0.02 ENSRNOT00000033863
zinc finger protein 831
chr3_-_160301552 0.02 ENSRNOT00000014498
regulating synaptic membrane exocytosis 4
chr3_+_122544788 0.02 ENSRNOT00000063828
transglutaminase 3
chr3_+_128756799 0.02 ENSRNOT00000049855
ENSRNOT00000042853
phospholipase C, beta 4
chr8_-_103190243 0.02 ENSRNOT00000075305
carbohydrate sulfotransferase 2
chr6_-_26875376 0.02 ENSRNOT00000011838
transmembrane protein 214
chr10_-_91986632 0.02 ENSRNOT00000087824
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr13_-_86671515 0.02 ENSRNOT00000082869

chr11_+_28692708 0.02 ENSRNOT00000002135
keratin associated protein 13-1
chr8_-_109560747 0.02 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr9_-_92405117 0.02 ENSRNOT00000079452
thyroid hormone receptor interactor 12
chr8_+_79489790 0.02 ENSRNOT00000091722
protogenin
chr20_-_45126062 0.02 ENSRNOT00000000720
similar to KIAA1919 protein
chr1_-_261669584 0.02 ENSRNOT00000020568
ENSRNOT00000076555
cartilage acidic protein 1
chrX_+_71342775 0.02 ENSRNOT00000004888
integrin subunit beta 1 binding protein 2
chr16_+_16949232 0.01 ENSRNOT00000047499

chr8_+_57936650 0.01 ENSRNOT00000089686
exophilin 5
chr18_+_30375798 0.01 ENSRNOT00000060497
protocadherin beta 2
chr5_-_75116490 0.01 ENSRNOT00000042788
thioredoxin domain containing 8
chr8_+_59457018 0.01 ENSRNOT00000017900
iron responsive element binding protein 2
chr1_-_175895510 0.01 ENSRNOT00000064535
eukaryotic translation initiation factor 4, gamma 2
chr3_+_94035905 0.01 ENSRNOT00000014767
similar to RIKEN cDNA A930018P22
chr15_+_27739251 0.01 ENSRNOT00000011840
poly (ADP-ribose) polymerase 2
chr10_+_11786121 0.01 ENSRNOT00000033919
SLX4 structure-specific endonuclease subunit
chr2_+_60131776 0.01 ENSRNOT00000080786
prolactin receptor
chr7_+_138707426 0.01 ENSRNOT00000037874
PC-esterase domain containing 1B
chr15_-_37926715 0.01 ENSRNOT00000013901
exportin 4
chr3_+_80468154 0.01 ENSRNOT00000021837
cytoskeleton associated protein 5
chr19_+_39063998 0.01 ENSRNOT00000081116
hyaluronan synthase 3
chr5_-_77031120 0.01 ENSRNOT00000022987
INTS3 and NABP interacting protein
chr9_-_11108741 0.01 ENSRNOT00000072357
coiled-coil domain containing 94
chr10_-_78690857 0.01 ENSRNOT00000089255
similar to glyceraldehyde-3-phosphate dehydrogenase
chr10_+_53713938 0.01 ENSRNOT00000004236
ENSRNOT00000086599
ENSRNOT00000085582
myosin heavy chain 2
chr18_+_29951094 0.01 ENSRNOT00000027402
protocadherin alpha-1-like
chr3_+_80556668 0.01 ENSRNOT00000079118
Rho GTPase activating protein 1
chr14_+_11199404 0.01 ENSRNOT00000003106
heterogeneous nuclear ribonucleoprotein D-like
chr8_+_22423467 0.01 ENSRNOT00000085320
interleukin enhancer binding factor 3
chr15_+_105851542 0.01 ENSRNOT00000086959
RAS related protein 2a
chr10_-_98544447 0.01 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chr10_+_53781239 0.01 ENSRNOT00000082871
myosin heavy chain 2
chr16_+_26906716 0.01 ENSRNOT00000064297
carboxypeptidase E
chr15_+_32809069 0.00 ENSRNOT00000070848

chr7_-_117068332 0.00 ENSRNOT00000082433
family with sequence similarity 83, member H
chr12_-_50314406 0.00 ENSRNOT00000079256
Hermansky-Pudlak syndrome 4
chr7_+_13996966 0.00 ENSRNOT00000009615
olfactory receptor 1087
chr9_+_100137881 0.00 ENSRNOT00000036328
G protein-coupled receptor 35
chr14_+_37116492 0.00 ENSRNOT00000002921
sarcoglycan, beta
chrX_+_15598652 0.00 ENSRNOT00000082383
coiled-coil domain containing 120
chr1_-_174119815 0.00 ENSRNOT00000019368
tripartite motif-containing 66
chr14_-_14689554 0.00 ENSRNOT00000002814
Fraser extracellular matrix complex subunit 1
chr18_-_35817117 0.00 ENSRNOT00000015172
ENSRNOT00000085714
mutated in colorectal cancers
chr18_+_2416871 0.00 ENSRNOT00000081399
GATA binding protein 6
chr1_+_44311513 0.00 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr15_-_29993639 0.00 ENSRNOT00000071822

chr1_+_125367280 0.00 ENSRNOT00000022049
amyloid beta precursor protein binding family A member 2
chr9_-_71798265 0.00 ENSRNOT00000043766
crystallin, gamma B
chr3_+_170380719 0.00 ENSRNOT00000055101
cleavage stimulation factor subunit 1
chr10_-_5344121 0.00 ENSRNOT00000003479
nucleotide binding protein 1
chr1_-_66645214 0.00 ENSRNOT00000084168
eukaryotic translation initiation factor 3, subunit 6 48kDa-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0038086 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0071914 prominosome(GO:0071914)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)