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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Foxa3
Z-value: 0.42
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Transcription factors associated with Foxa3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxa3 | rn6_v1_chr1_-_79930263_79930263 | -0.66 | 2.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_51614676 Show fit | 0.22 |
ENSRNOT00000060494
|
ankyrin repeat and SOCS box containing 15 |
|
| chr12_-_36398206 Show fit | 0.22 |
ENSRNOT00000090944
ENSRNOT00000058492 |
transmembrane protein 132B |
|
| chr9_+_27034022 Show fit | 0.20 |
ENSRNOT00000029696
|
progestin and adipoQ receptor family member 8 |
|
| chr10_-_27179900 Show fit | 0.18 |
ENSRNOT00000082445
|
gamma-aminobutyric acid type A receptor gamma 2 subunit |
|
| chr3_-_158328881 Show fit | 0.17 |
ENSRNOT00000044466
|
protein tyrosine phosphatase, receptor type, T |
|
| chr1_-_78521999 Show fit | 0.17 |
ENSRNOT00000021223
|
Rho GTPase activating protein 35 |
|
| chr10_-_37311625 Show fit | 0.16 |
ENSRNOT00000043343
|
jade family PHD finger 2 |
|
| chr7_+_23403891 Show fit | 0.15 |
ENSRNOT00000037918
|
synapsin III |
|
| chr13_+_43850751 Show fit | 0.14 |
ENSRNOT00000004995
|
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
|
| chr18_+_30890869 Show fit | 0.14 |
ENSRNOT00000060466
|
protocadherin gamma subfamily B, 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Foxa3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.0 | 0.2 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.0 | 0.2 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 0.1 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) |
| 0.0 | 0.1 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.0 | 0.1 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
| 0.0 | 0.1 | GO:2000426 | regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.0 | 0.1 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.0 | 0.1 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.1 | GO:0072675 | osteoclast fusion(GO:0072675) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.1 | GO:0070110 | interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110) |
| 0.0 | 0.1 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097) |
| 0.0 | 0.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 0.1 | GO:0001605 | adrenomedullin receptor activity(GO:0001605) |
| 0.0 | 0.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.0 | 0.1 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.1 | GO:0016890 | site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) |
| 0.0 | 0.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.1 | GO:0001846 | opsonin binding(GO:0001846) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.2 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 0.2 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.1 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |