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GSE49485: Hypoxia transcriptome sequencing of rat brain.
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Results for Fos
Z-value: 0.63
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Transcription factors associated with Fos
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Fos | rn6_v1_chr6_+_109300433_109300433 | 0.50 | 3.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_+_43357888 Show fit | 0.42 |
ENSRNOT00000022329
|
secretagogin, EF-hand calcium binding protein |
|
| chr10_-_90312386 Show fit | 0.27 |
ENSRNOT00000028445
|
solute carrier family 4 member 1 |
|
| chr20_+_5040337 Show fit | 0.25 |
ENSRNOT00000068435
|
chloride intracellular channel 1 |
|
| chr20_+_295250 Show fit | 0.24 |
ENSRNOT00000000955
|
chloride intracellular channel 2 |
|
| chr5_-_151397603 Show fit | 0.22 |
ENSRNOT00000076866
|
G protein-coupled receptor 3 |
|
| chr4_+_33638709 Show fit | 0.21 |
ENSRNOT00000009888
ENSRNOT00000034719 ENSRNOT00000052333 |
tachykinin, precursor 1 |
|
| chr1_+_91152635 Show fit | 0.21 |
ENSRNOT00000073438
|
dermokine-like |
|
| chr18_+_36371041 Show fit | 0.18 |
ENSRNOT00000025408
|
SH3 domain containing ring finger 2 |
|
| chr4_+_169147243 Show fit | 0.18 |
ENSRNOT00000011580
|
epithelial membrane protein 1 |
|
| chr1_-_124803363 Show fit | 0.18 |
ENSRNOT00000066380
|
Kruppel-like factor 13 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Fos
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.1 | 0.3 | GO:0010037 | response to carbon dioxide(GO:0010037) |
| 0.0 | 0.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.0 | 0.2 | GO:2000851 | positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851) |
| 0.0 | 0.2 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.0 | 0.2 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.0 | 0.1 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.0 | 0.1 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.0 | 0.1 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.0 | 0.1 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.1 | GO:0097413 | Lewy body(GO:0097413) |
| 0.0 | 0.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.0 | GO:1990622 | CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.3 | GO:0015106 | bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.0 | 0.1 | GO:0002134 | UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.0 | 0.1 | GO:0008481 | sphinganine kinase activity(GO:0008481) |
| 0.0 | 0.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.1 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.0 | 0.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 0.1 | GO:0045545 | syndecan binding(GO:0045545) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |