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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Ezh2_Atf2_Ikzf1

Z-value: 0.49

Motif logo

Transcription factors associated with Ezh2_Atf2_Ikzf1

Gene Symbol Gene ID Gene Info
ENSRNOG00000006048 enhancer of zeste 2 polycomb repressive complex 2 subunit
ENSRNOG00000001597 activating transcription factor 2
ENSRNOG00000004444 IKAROS family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf2rn6_v1_chr3_-_60795951_607959511.003.7e-04Click!
Ikzf1rn6_v1_chr14_+_91783514_917835140.977.6e-03Click!
Ezh2rn6_v1_chr4_-_77347011_773470110.247.0e-01Click!

Activity profile of Ezh2_Atf2_Ikzf1 motif

Sorted Z-values of Ezh2_Atf2_Ikzf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_58965552 0.27 ENSRNOT00000002068
mitogen-activated protein kinase kinase kinase 20
chr12_-_10307265 0.23 ENSRNOT00000092627
WAS protein family, member 3
chr1_-_43638161 0.23 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr12_+_13810180 0.22 ENSRNOT00000084865
ENSRNOT00000038203
trinucleotide repeat containing 18
chr14_+_8080565 0.21 ENSRNOT00000092395
mitogen activated protein kinase 10
chr15_-_110046687 0.21 ENSRNOT00000057404
ENSRNOT00000006624
ENSRNOT00000089695
sodium leak channel, non-selective
chr18_+_27558089 0.21 ENSRNOT00000027499
family with sequence similarity 53, member C
chr4_+_22859622 0.20 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr4_-_11497531 0.19 ENSRNOT00000078799
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_+_47019326 0.19 ENSRNOT00000006984
Smith-Magenis syndrome chromosome region, candidate 8
chr7_-_59587382 0.19 ENSRNOT00000091427
ENSRNOT00000066396
CCR4-NOT transcription complex, subunit 2
chr9_+_82571269 0.18 ENSRNOT00000026941
SPEG complex locus
chr10_-_92476109 0.17 ENSRNOT00000089029
KAT8 regulatory NSL complex subunit 1
chr15_-_54528480 0.16 ENSRNOT00000066888
fibronectin type III domain containing 3a
chr16_-_6245644 0.15 ENSRNOT00000040759
calcium voltage-gated channel subunit alpha1 D
chr2_-_157058194 0.15 ENSRNOT00000076409

chr6_-_86713370 0.15 ENSRNOT00000005821
kelch-like family member 28
chr7_+_123510804 0.15 ENSRNOT00000010491
septin 3
chr3_+_82548959 0.15 ENSRNOT00000000009
ALX homeobox 4
chr10_+_42614713 0.15 ENSRNOT00000081136
ENSRNOT00000073148
glutamate ionotropic receptor AMPA type subunit 1
chr18_+_30562178 0.14 ENSRNOT00000040998
protocadherin beta-16-like
chr16_-_20097287 0.14 ENSRNOT00000025162
unc-13 homolog A
chr12_+_21767606 0.14 ENSRNOT00000059602
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr14_+_109533792 0.14 ENSRNOT00000067690
ankyrin repeat domain-containing protein 29-like
chr14_-_84751886 0.13 ENSRNOT00000078838
myotubularin related protein 3
chr10_+_47018974 0.13 ENSRNOT00000079375
Smith-Magenis syndrome chromosome region, candidate 8
chr7_+_119820537 0.13 ENSRNOT00000077256
ENSRNOT00000056221
cytohesin 4
chr20_-_19637958 0.13 ENSRNOT00000074657
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr1_+_187149453 0.13 ENSRNOT00000082738
xylosyltransferase 1
chr6_-_147172022 0.13 ENSRNOT00000080675
integrin subunit beta 8
chr17_+_85364483 0.13 ENSRNOT00000064257
BMI1 proto-oncogene, polycomb ring finger
chr3_-_72052990 0.13 ENSRNOT00000064009
ENSRNOT00000081400
catenin delta 1
chr1_-_101323960 0.13 ENSRNOT00000041513
transient receptor potential cation channel, subfamily M, member 4
chr3_-_113312127 0.12 ENSRNOT00000065285
microfibrillar-associated protein 1A
chr11_+_69484293 0.12 ENSRNOT00000049292
kalirin, RhoGEF kinase
chr1_+_101517714 0.12 ENSRNOT00000028423
pleckstrin homology domain containing A4
chr2_+_201289357 0.12 ENSRNOT00000067358
T-box 15
chr6_+_86713803 0.12 ENSRNOT00000005861
family with sequence similarity 179, member B
chrX_-_19386541 0.11 ENSRNOT00000072722

chr15_-_33250546 0.11 ENSRNOT00000017857
similar to RIKEN cDNA 4931414P19
chr3_+_71114100 0.11 ENSRNOT00000088549
ENSRNOT00000006961
integrin subunit alpha V
chr15_-_43542939 0.11 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr5_-_58469399 0.11 ENSRNOT00000013213
phosphatidylinositol glycan anchor biosynthesis, class O
chr2_+_122368265 0.11 ENSRNOT00000078321
ATPase phospholipid transporting 11B (putative)
chr18_-_75207306 0.11 ENSRNOT00000021717
SET binding protein 1
chr1_+_166125474 0.11 ENSRNOT00000091822
FCH and double SH3 domains 2
chr10_+_35343189 0.11 ENSRNOT00000083688
mitogen-activated protein kinase 9
chr4_-_16654811 0.11 ENSRNOT00000008637
piccolo (presynaptic cytomatrix protein)
chr9_-_63637677 0.10 ENSRNOT00000049259
SATB homeobox 2
chrX_-_116792707 0.10 ENSRNOT00000049482
angiomotin
chr3_+_161149935 0.10 ENSRNOT00000073626
WAP four-disulfide core domain 13
chrX_-_26376467 0.10 ENSRNOT00000051655
ENSRNOT00000036502
Rho GTPase activating protein 6
chr17_-_10766253 0.10 ENSRNOT00000000117
complexin 2
chr8_+_12160067 0.10 ENSRNOT00000036338
mastermind-like transcriptional coactivator 2
chrX_-_152642531 0.10 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr9_+_73433252 0.10 ENSRNOT00000092540
microtubule-associated protein 2
chr4_+_51614676 0.10 ENSRNOT00000060494
ankyrin repeat and SOCS box containing 15
chr17_+_81922329 0.10 ENSRNOT00000031542
calcium voltage-gated channel auxiliary subunit beta 2
chr18_-_18079560 0.10 ENSRNOT00000072093

chr5_+_167141875 0.09 ENSRNOT00000089314
solute carrier family 2 member 5
chr3_+_7035169 0.09 ENSRNOT00000036601
protein phosphatase 1, regulatory subunit 26
chr9_+_118849302 0.09 ENSRNOT00000087592
DLG associated protein 1
chr14_-_5006594 0.09 ENSRNOT00000076571
zinc finger protein 326
chr2_+_207930796 0.09 ENSRNOT00000047827
potassium voltage-gated channel subfamily D member 3
chr3_+_103773459 0.09 ENSRNOT00000079727
solute carrier family 12, member 6
chr15_-_24056073 0.09 ENSRNOT00000015100
WD repeat and HMG-box DNA binding protein 1
chr10_+_42618487 0.09 ENSRNOT00000071615
glutamate ionotropic receptor AMPA type subunit 1
chr1_-_49844547 0.09 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr17_+_9236249 0.09 ENSRNOT00000015878
TIFA inhibitor
chr3_-_7796385 0.09 ENSRNOT00000082489
netrin G2
chr15_-_48445588 0.09 ENSRNOT00000077197
ENSRNOT00000018583
exostosin-like glycosyltransferase 3
chr5_-_158439078 0.09 ENSRNOT00000025517
kelch domain containing 7A
chrX_+_159081445 0.09 ENSRNOT00000056688

chr9_+_60039297 0.09 ENSRNOT00000016262
solute carrier family 39 member 10
chr2_+_36246628 0.08 ENSRNOT00000013618
5-hydroxytryptamine receptor 1A
chr4_+_163358009 0.08 ENSRNOT00000082064
killer cell lectin like receptor D1
chr3_-_72113680 0.08 ENSRNOT00000009708
zinc finger, DHHC-type containing 5
chr18_+_29966245 0.08 ENSRNOT00000074028
protocadherin alpha 4
chr5_+_90818736 0.08 ENSRNOT00000093480
ENSRNOT00000009083
lysine demethylase 4C
chr1_-_126211439 0.08 ENSRNOT00000014988
tight junction protein 1
chr4_-_155563249 0.08 ENSRNOT00000011298
solute carrier family 2 member 3
chr4_+_6282278 0.08 ENSRNOT00000010349
lysine methyltransferase 2C
chr19_-_52186260 0.08 ENSRNOT00000020838
membrane-bound transcription factor peptidase, site 1
chr10_-_65963932 0.08 ENSRNOT00000011726
nemo like kinase
chr6_-_4520604 0.08 ENSRNOT00000042230
ENSRNOT00000043870
ENSRNOT00000070918
ENSRNOT00000046246
ENSRNOT00000052367
ENSRNOT00000042251
solute carrier family 8 member A1
chr2_+_150756185 0.08 ENSRNOT00000088461
ENSRNOT00000036808
muscleblind-like splicing regulator 1
chr18_-_38088457 0.08 ENSRNOT00000077814
janus kinase and microtubule interacting protein 2
chr18_+_30954609 0.08 ENSRNOT00000086893
protocadherin gamma subfamily C, 3
chr10_-_27179254 0.08 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chrX_+_62363757 0.08 ENSRNOT00000091240
aristaless related homeobox
chr6_+_64252970 0.08 ENSRNOT00000093700
patatin-like phospholipase domain containing 8
chr15_-_77736892 0.08 ENSRNOT00000057924
protocadherin 9
chr5_-_168734296 0.08 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr2_+_186980992 0.08 ENSRNOT00000020717
Rho guanine nucleotide exchange factor 11
chr9_-_66033871 0.08 ENSRNOT00000035209
ALS2, alsin Rho guanine nucleotide exchange factor
chr20_+_3823596 0.08 ENSRNOT00000087670
retinoid X receptor beta
chr3_+_8192575 0.08 ENSRNOT00000060977
Rap guanine nucleotide exchange factor 1
chr17_-_58292624 0.08 ENSRNOT00000047512
adenosine deaminase, RNA-specific, B2
chr2_+_266315036 0.08 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr14_-_13058172 0.08 ENSRNOT00000002746
ENSRNOT00000071706
PR/SET domain 8
chr3_+_131351587 0.08 ENSRNOT00000010835
BTB domain containing 3
chr3_-_64554953 0.08 ENSRNOT00000067452
serine/arginine repetitive matrix protein 1-like
chr7_-_120770435 0.07 ENSRNOT00000077000
DEAD-box helicase 17
chr20_-_5485837 0.07 ENSRNOT00000092272
ENSRNOT00000000559
ENSRNOT00000092597
death-domain associated protein
chrX_+_62363953 0.07 ENSRNOT00000083362
aristaless related homeobox
chr20_-_6548179 0.07 ENSRNOT00000093711
LEM domain containing 2
chrX_+_80213332 0.07 ENSRNOT00000042827
SH3 domain binding glutamate-rich protein like
chr20_-_3793985 0.07 ENSRNOT00000049540
ENSRNOT00000086293
RT1 class I, locus CE16
chr9_-_43022998 0.07 ENSRNOT00000063781
ENSRNOT00000089843
lectin, mannose-binding 2-like
chr20_-_31956649 0.07 ENSRNOT00000072429
hexokinase 1
chr4_-_22424862 0.07 ENSRNOT00000082359
ATP binding cassette subfamily B member 1A
chr18_+_30885789 0.07 ENSRNOT00000044434
protocadherin gamma subfamily A, 9
chr6_+_86713604 0.07 ENSRNOT00000059271
family with sequence similarity 179, member B
chr1_+_199037544 0.07 ENSRNOT00000025499
ring finger protein 40
chr10_-_103685844 0.07 ENSRNOT00000064284
Cd300 molecule-like family member F
chr8_-_13906355 0.07 ENSRNOT00000029634
centrosomal protein 295
chr17_+_60059949 0.07 ENSRNOT00000025458
membrane palmitoylated protein 7
chr13_+_57131395 0.07 ENSRNOT00000017884
potassium sodium-activated channel subfamily T member 2
chrX_-_29648359 0.07 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr13_+_50196042 0.07 ENSRNOT00000090858
zinc finger CCCH-type containing 11A
chr8_-_39093277 0.07 ENSRNOT00000043344
roundabout homolog 4-like
chr12_-_44381289 0.07 ENSRNOT00000001493
nitric oxide synthase 1
chr3_+_139695028 0.07 ENSRNOT00000089098
solute carrier family 24 member 3
chr18_-_32670665 0.07 ENSRNOT00000019409
nuclear receptor subfamily 3, group C, member 1
chr15_-_88036354 0.07 ENSRNOT00000014747
endothelin receptor type B
chr7_-_104749552 0.07 ENSRNOT00000079981
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr2_+_104744461 0.07 ENSRNOT00000016083
ENSRNOT00000082627
ceruloplasmin
chr16_-_10296341 0.07 ENSRNOT00000083990
zinc finger protein 488
chr2_+_144191846 0.07 ENSRNOT00000000102
SMAD family member 9
chr17_-_1093873 0.07 ENSRNOT00000086130
patched 1
chr15_-_23606634 0.07 ENSRNOT00000075602
glia maturation factor, beta
chr5_+_64566804 0.07 ENSRNOT00000073192
TGF-beta receptor type-1-like
chr8_-_116893057 0.07 ENSRNOT00000082113
bassoon (presynaptic cytomatrix protein)
chr14_+_79205466 0.06 ENSRNOT00000085534
TBC1 domain family, member 14
chr18_+_30831365 0.06 ENSRNOT00000067185
protocadherin gamma subfamily A, 4
chr20_+_6211420 0.06 ENSRNOT00000000624
potassium channel tetramerization domain containing 20
chr2_+_185590986 0.06 ENSRNOT00000088807
ENSRNOT00000088188
LPS responsive beige-like anchor protein
chr1_-_80471527 0.06 ENSRNOT00000023867
protein phosphatase 1, regulatory subunit 37
chr10_-_36419926 0.06 ENSRNOT00000004902
zinc finger protein 354B
chr1_-_73732118 0.06 ENSRNOT00000077964
leukocyte receptor cluster member 8
chr4_-_157155609 0.06 ENSRNOT00000016330
complement C1s
chr5_-_152762165 0.06 ENSRNOT00000022921
selenoprotein N
chr1_+_100593892 0.06 ENSRNOT00000027062
potassium voltage-gated channel subfamily C member 3
chr10_-_42928461 0.06 ENSRNOT00000058619
family with sequence similarity 114, member A2
chr1_-_92119951 0.06 ENSRNOT00000018153
ENSRNOT00000092121
zinc finger protein 507
chr11_-_62451149 0.06 ENSRNOT00000093686
ENSRNOT00000081443
zinc finger and BTB domain containing 20
chr1_-_4011161 0.06 ENSRNOT00000044778
syntaxin binding protein 5
chr1_+_25174456 0.06 ENSRNOT00000092830
clavesin 2
chr18_+_30913842 0.06 ENSRNOT00000026947
protocadherin gamma subfamily C, 3
chr12_+_6403940 0.06 ENSRNOT00000083484
beta 3-glucosyltransferase
chr7_-_50638798 0.06 ENSRNOT00000048880
synaptotagmin 1
chr13_+_46169963 0.06 ENSRNOT00000005212
thrombospondin type 1 domain containing 7B
chr2_-_173087648 0.06 ENSRNOT00000091079
IQ motif containing J
chr13_+_52667969 0.06 ENSRNOT00000084986
ENSRNOT00000050284
troponin T2, cardiac type
chr3_-_3855391 0.06 ENSRNOT00000025764
inositol polyphosphate-5-phosphatase E
chr13_+_34365147 0.06 ENSRNOT00000093066
cytoplasmic linker associated protein 1
chr17_-_1085885 0.06 ENSRNOT00000026287
patched 1
chr1_-_219388009 0.06 ENSRNOT00000001550
calcium binding protein 4
chr7_+_70753101 0.06 ENSRNOT00000090001
R3H domain containing 2
chr7_+_144503534 0.06 ENSRNOT00000021543
tubulin folding cofactor A
chr2_-_210454737 0.05 ENSRNOT00000079993
adenosylhomocysteinase-like 1
chr1_-_201906286 0.05 ENSRNOT00000064511
ENSRNOT00000036625
similar to RIKEN cDNA 1700063I17
chr18_-_77317969 0.05 ENSRNOT00000090369
nuclear factor of activated T-cells 1
chr4_+_168599331 0.05 ENSRNOT00000086719
cAMP responsive element binding protein-like 2
chr8_+_102304095 0.05 ENSRNOT00000011358
solute carrier family 9 member A9
chr1_+_234252757 0.05 ENSRNOT00000091814
RAR-related orphan receptor B
chr1_+_166478005 0.05 ENSRNOT00000030037
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_17311112 0.05 ENSRNOT00000001732
G protein-coupled estrogen receptor 1
chr6_+_64789940 0.05 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr2_+_186980793 0.05 ENSRNOT00000091336
Rho guanine nucleotide exchange factor 11
chr1_+_128924966 0.05 ENSRNOT00000019267
insulin-like growth factor 1 receptor
chr2_+_188141350 0.05 ENSRNOT00000078913
gon-4 like
chr19_-_58735173 0.05 ENSRNOT00000030077
pecanex homolog 2 (Drosophila)
chr2_+_219628695 0.05 ENSRNOT00000067324
SAS-6 centriolar assembly protein
chr20_+_20105047 0.05 ENSRNOT00000082181
ankyrin 3
chr15_+_120372 0.05 ENSRNOT00000007828
discs large MAGUK scaffold protein 5
chr16_+_2743823 0.05 ENSRNOT00000087873
Rho guanine nucleotide exchange factor 3
chr1_+_87697005 0.05 ENSRNOT00000028158
zinc finger protein 84
chrX_+_53360839 0.05 ENSRNOT00000091467
ENSRNOT00000034372
ENSRNOT00000081061
dystrophin
chr18_+_55505993 0.05 ENSRNOT00000043736
similar to interferon-inducible GTPase
chr14_+_63095720 0.05 ENSRNOT00000006071
PPARG coactivator 1 alpha
chrX_+_71155601 0.05 ENSRNOT00000076453
ENSRNOT00000048521
forkhead box O4
chr18_+_56379890 0.05 ENSRNOT00000078764
platelet derived growth factor receptor beta
chr7_+_73273985 0.05 ENSRNOT00000077730
POP1 homolog, ribonuclease P/MRP subunit
chr18_+_1723565 0.05 ENSRNOT00000033468
growth regulation by estrogen in breast cancer 1 like
chr5_-_147886615 0.05 ENSRNOT00000087556
karyopherin subunit alpha 6
chr2_-_189400323 0.05 ENSRNOT00000024364
ubiquitin associated protein 2-like
chr10_-_85435016 0.05 ENSRNOT00000079921
RIKEN cDNA 4933428G20 gene
chr3_-_111354419 0.05 ENSRNOT00000038365
exonuclease 3'-5' domain containing 1
chr12_-_11175917 0.05 ENSRNOT00000079573
zinc finger with KRAB and SCAN domains 5
chrX_+_68771100 0.05 ENSRNOT00000043872
StAR-related lipid transfer domain containing 8
chr17_+_70262363 0.05 ENSRNOT00000048933
family with sequence similarity 208, member B
chr1_+_87563975 0.05 ENSRNOT00000088772
zinc finger protein 30
chr17_+_49417067 0.05 ENSRNOT00000090024
POU domain, class 6, transcription factor 2
chr6_+_27887797 0.05 ENSRNOT00000015827
additional sex combs like 2, transcriptional regulator
chr10_-_73690860 0.05 ENSRNOT00000004876
ENSRNOT00000075843
integrator complex subunit 2
chr1_+_277459200 0.05 ENSRNOT00000086008

chr1_+_199323628 0.05 ENSRNOT00000036187
zinc finger protein 646
chr6_-_76608864 0.05 ENSRNOT00000010824
Ral GTPase activating protein catalytic alpha subunit 1
chr9_+_71915421 0.05 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing

Network of associatons between targets according to the STRING database.

First level regulatory network of Ezh2_Atf2_Ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.0 0.1 GO:0021997 epidermal cell fate specification(GO:0009957) neural plate axis specification(GO:0021997)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.1 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0071454 cellular response to anoxia(GO:0071454)
0.0 0.1 GO:2000426 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.1 GO:1905235 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:0016203 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.0 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.0 GO:1904708 granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.0 GO:0015675 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
0.0 0.1 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.0 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.0 0.1 GO:0051595 response to methylglyoxal(GO:0051595)
0.0 0.1 GO:0015679 plasma membrane copper ion transport(GO:0015679)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0071000 response to magnetism(GO:0071000)
0.0 0.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.0 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0021540 corpus callosum morphogenesis(GO:0021540)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.0 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.0 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0033222 xylose binding(GO:0033222)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.0 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.0 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA