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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Ets1

Z-value: 0.79

Motif logo

Transcription factors associated with Ets1

Gene Symbol Gene ID Gene Info
ENSRNOG00000008941 ETS proto-oncogene 1, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ets1rn6_v1_chr8_+_33816386_338163860.622.6e-01Click!

Activity profile of Ets1 motif

Sorted Z-values of Ets1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_73778595 0.49 ENSRNOT00000076081
ENSRNOT00000075926
ENSRNOT00000003782
ring finger protein, LIM domain interacting
chr10_-_64642292 0.45 ENSRNOT00000084670
active BCR-related
chr6_+_104291071 0.45 ENSRNOT00000006798
solute carrier family 39, member 9
chr8_-_21968415 0.44 ENSRNOT00000067325
ENSRNOT00000064932
DNA methyltransferase 1
chr2_+_190003223 0.38 ENSRNOT00000015712
S100 calcium binding protein A5
chr3_-_152382529 0.38 ENSRNOT00000027076
SCAN domain-containing 1
chr15_-_57805184 0.36 ENSRNOT00000000168
component of oligomeric golgi complex 3
chr3_-_38277440 0.36 ENSRNOT00000037857
signal transducing adaptor molecule 2
chr4_-_63039422 0.34 ENSRNOT00000015808
myotrophin
chr5_-_169630340 0.33 ENSRNOT00000087043
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr7_+_143707237 0.29 ENSRNOT00000074212
tensin 2
chr3_+_101010899 0.28 ENSRNOT00000073258
lin-7 homolog C, crumbs cell polarity complex component
chr9_-_41337498 0.27 ENSRNOT00000039480
family with sequence similarity 168, member B
chr3_-_148932878 0.27 ENSRNOT00000013881
nucleolar protein 4-like
chr11_+_61531416 0.27 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr10_+_85301875 0.26 ENSRNOT00000080935
suppressor of cytokine signaling 7
chr10_-_64657089 0.26 ENSRNOT00000080703
active BCR-related
chr11_+_71151132 0.26 ENSRNOT00000082594
ENSRNOT00000082435
RUN and cysteine rich domain containing beclin 1 interacting protein
chr3_-_92242318 0.25 ENSRNOT00000007018
tripartite motif-containing 44
chr1_-_78521999 0.25 ENSRNOT00000021223
Rho GTPase activating protein 35
chr16_+_71058022 0.25 ENSRNOT00000066901
BCL2-associated athanogene 4
chr11_-_30428073 0.24 ENSRNOT00000047741
SR-related CTD-associated factor 4
chr9_+_14551758 0.24 ENSRNOT00000017157
nuclear transcription factor Y subunit alpha
chr11_+_16826399 0.24 ENSRNOT00000050701
coxsackie virus and adenovirus receptor
chr2_-_183582553 0.24 ENSRNOT00000014236
ADP-ribosylation factor interacting protein 1
chr1_-_72339395 0.24 ENSRNOT00000021772
zinc finger protein 580
chr13_-_37287458 0.23 ENSRNOT00000003391
insulin induced gene 2
chr8_+_70522092 0.23 ENSRNOT00000025873
dipeptidylpeptidase 8
chr11_+_64601029 0.23 ENSRNOT00000004138
Rho GTPase activating protein 31
chr13_+_97838361 0.23 ENSRNOT00000003641
consortin, connexin sorting protein
chr19_-_11451278 0.23 ENSRNOT00000026118
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr20_+_5646097 0.23 ENSRNOT00000090925
inositol 1,4,5-trisphosphate receptor, type 3
chr1_+_274245184 0.23 ENSRNOT00000018889
dual specificity phosphatase 5
chr4_+_148139528 0.21 ENSRNOT00000092594
ENSRNOT00000015620
ENSRNOT00000092613
WASH complex subunit 2C
chr5_-_146973932 0.21 ENSRNOT00000007761
zinc finger protein 362
chr5_-_173653905 0.20 ENSRNOT00000038556
pleckstrin homology domain containing N1
chr10_-_56530842 0.20 ENSRNOT00000077451

chr17_+_15749978 0.20 ENSRNOT00000067311
FYVE, RhoGEF and PH domain containing 3
chr10_-_14299167 0.20 ENSRNOT00000042066
mitogen-activated protein kinase 8 interacting protein 3
chr5_-_79222687 0.20 ENSRNOT00000010516
AT-hook transcription factor
chrX_-_20070537 0.20 ENSRNOT00000093602
ENSRNOT00000003397
G protein nucleolar 3 like
chr14_-_13058172 0.20 ENSRNOT00000002746
ENSRNOT00000071706
PR/SET domain 8
chr15_+_37790141 0.20 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr3_+_71114100 0.19 ENSRNOT00000088549
ENSRNOT00000006961
integrin subunit alpha V
chr10_-_85435016 0.19 ENSRNOT00000079921
RIKEN cDNA 4933428G20 gene
chr1_-_198316882 0.19 ENSRNOT00000085304
ENSRNOT00000064985
TAO kinase 2
chr6_-_86713370 0.19 ENSRNOT00000005821
kelch-like family member 28
chr5_-_60559533 0.19 ENSRNOT00000092899
zinc finger and BTB domain containing 5
chr10_+_47018974 0.19 ENSRNOT00000079375
Smith-Magenis syndrome chromosome region, candidate 8
chr8_-_63034226 0.19 ENSRNOT00000043434
promyelocytic leukemia
chr14_-_86333424 0.18 ENSRNOT00000083191
NudC domain containing 3
chr3_+_80555196 0.18 ENSRNOT00000067318
Rho GTPase activating protein 1
chr14_-_84393421 0.18 ENSRNOT00000006911
coiled-coil domain containing 157
chr7_+_2795901 0.18 ENSRNOT00000047462
ankyrin repeat domain 52
chr12_+_38144855 0.18 ENSRNOT00000032274
hydroxycarboxylic acid receptor 1
chr13_-_88536728 0.18 ENSRNOT00000003950
U2AF homology motif kinase 1
chr10_+_47019326 0.18 ENSRNOT00000006984
Smith-Magenis syndrome chromosome region, candidate 8
chr20_-_5441706 0.18 ENSRNOT00000000549
VPS52 GARP complex subunit
chr1_-_72311856 0.18 ENSRNOT00000021286
Epsin 1
chr3_+_11679530 0.17 ENSRNOT00000074562
ENSRNOT00000071801
endoglin
chr4_-_155563249 0.17 ENSRNOT00000011298
solute carrier family 2 member 3
chr4_-_117296082 0.17 ENSRNOT00000021097
early growth response 4
chr7_+_133400485 0.17 ENSRNOT00000006219
contactin 1
chr2_-_252691886 0.17 ENSRNOT00000068739
protein kinase cAMP-activated catalytic subunit beta
chr10_-_14443010 0.17 ENSRNOT00000022142
transmembrane protein 204
chr6_+_107169528 0.17 ENSRNOT00000012495
presenilin 1
chr19_+_45938915 0.17 ENSRNOT00000065508
MON1 homolog B, secretory trafficking associated
chr6_+_28235695 0.17 ENSRNOT00000047210
DNA methyltransferase 3 alpha
chr4_+_163162211 0.17 ENSRNOT00000082537
C-type lectin domain family 1, member B
chr4_+_157523110 0.17 ENSRNOT00000081640
zinc finger protein 384
chr1_+_85437780 0.16 ENSRNOT00000093740
SPT5 homolog, DSIF elongation factor subunit
chr7_-_140245723 0.16 ENSRNOT00000088999
cyclin T1
chr3_-_162579201 0.16 ENSRNOT00000068328
zinc finger, MYND-type containing 8
chr7_-_11223649 0.16 ENSRNOT00000061191
major facilitator superfamily domain containing 12
chr10_+_89646195 0.16 ENSRNOT00000048140
DEAH-box helicase 8
chr2_-_118745766 0.16 ENSRNOT00000013858
zinc finger, matrin type 3
chr6_+_137824213 0.16 ENSRNOT00000056880
phosphofurin acidic cluster sorting protein 2
chr10_-_109333899 0.15 ENSRNOT00000006225
solute carrier family 38, member 10
chr2_-_204341676 0.15 ENSRNOT00000021713
solute carrier family 22, member 15
chr20_-_19637958 0.15 ENSRNOT00000074657
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr6_-_64170122 0.15 ENSRNOT00000093248
ENSRNOT00000005363
DnaJ heat shock protein family (Hsp40) member B9
chr10_+_59529785 0.15 ENSRNOT00000064840
ENSRNOT00000065181
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr1_+_81779380 0.15 ENSRNOT00000065865
ENSRNOT00000080143
ENSRNOT00000089592
ENSRNOT00000080840
Rho guanine nucleotide exchange factor 1
chrX_+_10964067 0.15 ENSRNOT00000093181
ENSRNOT00000066480
mediator complex subunit 14
chr13_+_50196042 0.15 ENSRNOT00000090858
zinc finger CCCH-type containing 11A
chr8_-_45215974 0.15 ENSRNOT00000010792
cytotoxic and regulatory T cell molecule
chr5_-_60559329 0.15 ENSRNOT00000017046
zinc finger and BTB domain containing 5
chr13_-_82607379 0.15 ENSRNOT00000051763
basic leucine zipper nuclear factor 1
chr11_+_24263281 0.14 ENSRNOT00000086946
GA binding protein transcription factor, alpha subunit
chr14_+_16491573 0.14 ENSRNOT00000002995
sosondowah ankyrin repeat domain family member B
chr3_+_122114108 0.14 ENSRNOT00000091935
signal-regulatory protein alpha
chr5_+_82587420 0.14 ENSRNOT00000014020
toll-like receptor 4
chr1_-_215846911 0.14 ENSRNOT00000089171
insulin-like growth factor 2
chr16_-_2367253 0.14 ENSRNOT00000083573
phosphodiesterase 12
chr7_-_130151414 0.14 ENSRNOT00000010467
plexin B2
chr7_-_93826665 0.14 ENSRNOT00000011344
TNF receptor superfamily member 11B
chr10_+_71278650 0.14 ENSRNOT00000092020
synergin, gamma
chr6_+_110093819 0.14 ENSRNOT00000013602
G patch domain containing 2-like
chr4_+_34282625 0.14 ENSRNOT00000011138
ENSRNOT00000086735
glucocorticoid induced 1
chrX_-_69218526 0.14 ENSRNOT00000092321
ENSRNOT00000074071
ENSRNOT00000092571
praja ring finger ubiquitin ligase 1
chr16_+_10727571 0.14 ENSRNOT00000084422
multimerin 2
chr7_-_2712723 0.14 ENSRNOT00000004363
interleukin 23 subunit alpha
chr20_+_4355175 0.14 ENSRNOT00000000510
G-protein signaling modulator 3
chr2_+_41157823 0.14 ENSRNOT00000066384
phosphodiesterase 4D
chr3_-_10269693 0.14 ENSRNOT00000021871
far upstream element binding protein 3
chr1_-_198577226 0.14 ENSRNOT00000055013
sialophorin
chr3_-_43117337 0.14 ENSRNOT00000078001
nuclear receptor subfamily 4, group A, member 2
chr10_-_85084850 0.14 ENSRNOT00000012462
TBK1 binding protein 1
chr15_-_4022223 0.14 ENSRNOT00000081997
zinc finger, SWIM-type containing 8
chr4_+_87026530 0.13 ENSRNOT00000018425
AVL9 cell migration associated
chr16_+_19068783 0.13 ENSRNOT00000017424
calcium homeostasis endoplasmic reticulum protein
chr12_+_18074033 0.13 ENSRNOT00000001727
integrator complex subunit 1-like
chr5_-_155316495 0.13 ENSRNOT00000017559
Eph receptor A8
chr4_-_78342863 0.13 ENSRNOT00000049038
GTPase, IMAP family member 6
chr7_+_14037620 0.13 ENSRNOT00000009606
synapse defective Rho GTPase homolog 1
chr14_+_84393182 0.13 ENSRNOT00000008355
splicing factor 3a, subunit 1
chr7_+_127081978 0.13 ENSRNOT00000022945
TBC1 domain family, member 22a
chr1_-_190965115 0.13 ENSRNOT00000023483

chr8_+_117280705 0.13 ENSRNOT00000085038
ubiquitin specific peptidase 19
chr12_-_6956914 0.13 ENSRNOT00000072129
ENSRNOT00000001210
ubiquitin specific peptidase like 1
chr19_-_19832812 0.13 ENSRNOT00000084657
poly(A) RNA polymerase D5, non-canonical
chr17_+_5225835 0.13 ENSRNOT00000022373
zinc finger CCHC-type containing 6
chr17_+_13670520 0.13 ENSRNOT00000019442
SHC adaptor protein 3
chr18_-_56115593 0.13 ENSRNOT00000045041
treacle ribosome biogenesis factor 1
chr7_-_107616038 0.13 ENSRNOT00000088752
src-like adaptor
chr15_+_24078280 0.13 ENSRNOT00000015511
ENSRNOT00000063807
mitogen-activated protein kinase 1 interacting protein 1-like
chr8_+_117246376 0.12 ENSRNOT00000074493
coiled-coil domain containing 71
chr13_-_51076852 0.12 ENSRNOT00000078993
adenosine A1 receptor
chr10_-_56491715 0.12 ENSRNOT00000020970
potassium channel tetramerization domain containing 11
chr18_+_56379890 0.12 ENSRNOT00000078764
platelet derived growth factor receptor beta
chr13_-_83202864 0.12 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr14_+_1463359 0.12 ENSRNOT00000070834
colony stimulating factor 2 receptor alpha subunit
chr1_+_199037544 0.12 ENSRNOT00000025499
ring finger protein 40
chr1_+_13595295 0.12 ENSRNOT00000079250
NHS-like 1
chr17_-_46794845 0.12 ENSRNOT00000077910
ENSRNOT00000090663
ENSRNOT00000078331
engulfment and cell motility 1
chr15_+_25933483 0.12 ENSRNOT00000018972
adaptor-related protein complex 5, mu 1 subunit
chr4_+_2711385 0.12 ENSRNOT00000035996
DnaJ heat shock protein family (Hsp40) member B6
chr12_+_12374790 0.12 ENSRNOT00000001347
tectonin beta-propeller repeat containing 1
chr6_-_132802206 0.12 ENSRNOT00000080163
ENSRNOT00000050350
tryptophanyl-tRNA synthetase
chr19_-_52252587 0.12 ENSRNOT00000020990
TATA-box binding protein associated factor, RNA polymerase 1 subunit C
chr2_-_190100276 0.12 ENSRNOT00000015351
S100 calcium binding protein A9
chr3_+_176865156 0.12 ENSRNOT00000019084
zinc finger CCCH-type and G-patch domain containing
chr2_-_211715311 0.12 ENSRNOT00000027738
pre-mRNA processing factor 38B
chr3_+_6211789 0.12 ENSRNOT00000012892
retinoid X receptor alpha
chr3_+_95707386 0.12 ENSRNOT00000005882
paired box 6
chr19_-_54652381 0.12 ENSRNOT00000065472
kelch domain containing 4
chr1_+_220428481 0.12 ENSRNOT00000027335
ras and Rab interactor 1
chr20_+_27954433 0.12 ENSRNOT00000064288
LIM zinc finger domain containing 1
chr19_-_22281778 0.12 ENSRNOT00000049624
phosphorylase kinase regulatory subunit beta
chr8_+_109455786 0.12 ENSRNOT00000039593
male-specific lethal 2 homolog (Drosophila)
chr10_-_13892997 0.11 ENSRNOT00000004192
TNF receptor associated factor 7
chr10_+_43067299 0.11 ENSRNOT00000003447
polypeptide N-acetylgalactosaminyltransferase 10
chr3_-_164239250 0.11 ENSRNOT00000012604
spermatogenesis associated 2
chr13_-_47979797 0.11 ENSRNOT00000080035
Ras association domain family member 5
chr17_-_27112820 0.11 ENSRNOT00000018359
bone morphogenetic protein 6
chr3_+_48096954 0.11 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr10_-_12916784 0.11 ENSRNOT00000004589
zinc finger protein 13
chr2_-_211831551 0.11 ENSRNOT00000039225
ENSRNOT00000090561
family with sequence similarity 102, member B
chr8_-_105462141 0.11 ENSRNOT00000066731
ENSRNOT00000078760
calsyntenin 2
chr7_-_36408588 0.11 ENSRNOT00000063946
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_199197138 0.11 ENSRNOT00000065187
F-box and leucine-rich repeat protein 19
chrX_+_82143789 0.11 ENSRNOT00000003724
POU class 3 homeobox 4
chr7_-_142180997 0.11 ENSRNOT00000087632
transcription factor CP2
chr1_+_222746023 0.11 ENSRNOT00000028787
atlastin GTPase 3
chr1_+_81365138 0.11 ENSRNOT00000026793
cell adhesion molecule 4
chr1_+_224882439 0.11 ENSRNOT00000024785
cholinergic receptor, muscarinic 1
chr7_-_122403667 0.11 ENSRNOT00000088814
megakaryoblastic leukemia (translocation) 1
chr10_+_90230441 0.11 ENSRNOT00000082722
transmembrane and ubiquitin-like domain containing 2
chr7_-_139907640 0.11 ENSRNOT00000045473
zinc finger protein 641
chr6_+_86713803 0.11 ENSRNOT00000005861
family with sequence similarity 179, member B
chr10_-_90995982 0.11 ENSRNOT00000093266
glial fibrillary acidic protein
chr5_-_160742479 0.11 ENSRNOT00000019447
kazrin, periplakin interacting protein
chr7_-_12673659 0.10 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
polypyrimidine tract binding protein 1
chr15_-_56970365 0.10 ENSRNOT00000047192
leucine rich repeats and calponin homology domain containing 1
chr8_+_4440876 0.10 ENSRNOT00000049325
ENSRNOT00000076529
ENSRNOT00000076748
platelet derived growth factor D
chr18_-_31071371 0.10 ENSRNOT00000060432
diaphanous-related formin 1
chrX_-_123515720 0.10 ENSRNOT00000092343
NFKB repressing factor
chr14_+_85230648 0.10 ENSRNOT00000089866
adaptor-related protein complex 1, beta 1 subunit
chr5_-_159602251 0.10 ENSRNOT00000011394
NECAP endocytosis associated 2
chr6_-_79306443 0.10 ENSRNOT00000030706
C-type lectin domain family 14, member A
chr8_+_49354115 0.10 ENSRNOT00000032837
myelin protein zero-like 3
chr8_-_128754514 0.10 ENSRNOT00000025019
C-X3-C motif chemokine receptor 1
chr5_-_113532878 0.10 ENSRNOT00000010173
caspase activity and apoptosis inhibitor 1
chr18_-_76984203 0.10 ENSRNOT00000089122
CTD phosphatase subunit 1
chr2_-_140334912 0.10 ENSRNOT00000015067
E74-like factor 2
chr4_+_140247313 0.10 ENSRNOT00000040255
ENSRNOT00000064025
ENSRNOT00000041130
ENSRNOT00000043646
inositol 1,4,5-trisphosphate receptor, type 1
chr5_+_173660921 0.10 ENSRNOT00000066561
NOC2-like nucleolar associated transcriptional repressor
chr20_-_6864387 0.10 ENSRNOT00000068527
peptidylprolyl isomerase like 1
chr7_+_12022285 0.10 ENSRNOT00000024080
RNA exonuclease 1 homolog
chr3_+_119484677 0.10 ENSRNOT00000037390
adaptor-related protein complex 4, epsilon 1 subunit
chr16_-_19918644 0.10 ENSRNOT00000083345
ENSRNOT00000023926
plasmalemma vesicle associated protein
chr4_-_125929002 0.10 ENSRNOT00000083271
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_+_157524423 0.10 ENSRNOT00000036654
zinc finger protein 384
chr2_+_116032455 0.10 ENSRNOT00000066495
polyhomeotic homolog 3
chr3_-_80875817 0.09 ENSRNOT00000091265
diacylglycerol kinase zeta
chr10_-_15211325 0.09 ENSRNOT00000027083
ras homolog family member T2
chr8_+_62368998 0.09 ENSRNOT00000025885
unc-51 like kinase 3
chr6_-_50786967 0.09 ENSRNOT00000009566
Cbl proto-oncogene like 1
chr4_+_56625561 0.09 ENSRNOT00000008356
ENSRNOT00000090808
ENSRNOT00000008972
calumenin
chr2_+_188139730 0.09 ENSRNOT00000056789
ENSRNOT00000077698
gon-4 like

Network of associatons between targets according to the STRING database.

First level regulatory network of Ets1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 0.5 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:0090309 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0019086 late viral transcription(GO:0019086)
0.1 0.2 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.2 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.3 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:0050713 PML body organization(GO:0030578) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:0051142 positive regulation of memory T cell differentiation(GO:0043382) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.2 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696)
0.0 0.1 GO:0002884 type IV hypersensitivity(GO:0001806) negative regulation of hypersensitivity(GO:0002884)
0.0 0.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.1 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0038091 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:2000860 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080) regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:1904844 regulation of renal output by angiotensin(GO:0002019) response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 0.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0060687 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0071899 odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:0010625 positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0007290 spermatid nucleus elongation(GO:0007290) epidermal stem cell homeostasis(GO:0036334)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0060717 chorion development(GO:0060717)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.0 GO:2000836 positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.0 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.0 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 0.2 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0036396 MIS complex(GO:0036396)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.0 GO:1990590 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0033222 xylose binding(GO:0033222)
0.1 0.2 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.0 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins