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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Esrrb_Esrra

Z-value: 1.85

Motif logo

Transcription factors associated with Esrrb_Esrra

Gene Symbol Gene ID Gene Info
ENSRNOG00000010259 estrogen-related receptor beta
ENSRNOG00000021139 estrogen related receptor, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esrrarn6_v1_chr1_-_222178725_2221787250.513.8e-01Click!
Esrrbrn6_v1_chr6_+_110410141_1104101410.286.4e-01Click!

Activity profile of Esrrb_Esrra motif

Sorted Z-values of Esrrb_Esrra motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_123106694 5.49 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr10_-_71849293 1.56 ENSRNOT00000003799
LIM homeobox 1
chr20_+_14095914 1.37 ENSRNOT00000093404
guanylyl cyclase domain containing 1
chr5_+_50381244 1.22 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr1_+_276659542 1.18 ENSRNOT00000019681
transcription factor 7 like 2
chr10_+_110139783 1.15 ENSRNOT00000054939
solute carrier family 16 member 3
chr2_-_123396147 1.01 ENSRNOT00000079004
transient receptor potential cation channel, subfamily C, member 3
chr2_-_14701903 0.96 ENSRNOT00000051895
cytochrome c oxidase subunit 7C
chr19_-_37427989 0.95 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chrX_-_40086870 0.94 ENSRNOT00000010027
small muscle protein, X-linked
chr4_-_123494742 0.94 ENSRNOT00000073268
solute carrier family 41, member 3
chr4_+_78263866 0.93 ENSRNOT00000033807
expressed sequence AI854703
chr3_+_147609095 0.90 ENSRNOT00000041456
sulfiredoxin 1
chr19_-_57333433 0.90 ENSRNOT00000024917
angiotensinogen
chr18_-_26211445 0.84 ENSRNOT00000027739
neuronal regeneration related protein
chr14_+_84237520 0.78 ENSRNOT00000083580
galactose-3-O-sulfotransferase 1
chr6_-_6842758 0.77 ENSRNOT00000006094
potassium voltage-gated channel modifier subfamily G member 3
chr12_+_47024442 0.76 ENSRNOT00000001545
cytochrome c oxidase subunit 6A1
chr10_-_15235740 0.74 ENSRNOT00000027170
MAPK regulated co-repressor interacting protein 2
chr1_-_167347662 0.68 ENSRNOT00000027641
ENSRNOT00000076592
ras homolog family member G
chr1_-_167005839 0.68 ENSRNOT00000027261
leucine rich repeat containing 51
chr1_+_274245184 0.67 ENSRNOT00000018889
dual specificity phosphatase 5
chr1_-_222468896 0.65 ENSRNOT00000028754
cytochrome c oxidase subunit 8A
chr4_-_148845267 0.64 ENSRNOT00000037397
transmembrane protein 72
chr8_+_48569328 0.60 ENSRNOT00000084030
coiled-coil domain containing 153
chr8_+_59900651 0.60 ENSRNOT00000020410
transmembrane protein 266
chr6_+_3012804 0.60 ENSRNOT00000061980
Rho guanine nucleotide exchange factor 33
chr2_-_123396386 0.59 ENSRNOT00000046700
transient receptor potential cation channel, subfamily C, member 3
chr4_-_165629996 0.59 ENSRNOT00000068185
ENSRNOT00000007427
Y box binding protein 3
chr13_-_85622314 0.58 ENSRNOT00000005719
microsomal glutathione S-transferase 3
chr19_+_52521809 0.57 ENSRNOT00000081019
kelch-like family member 36
chr1_-_222250980 0.57 ENSRNOT00000028734
nudix hydrolase 22
chr9_+_43259709 0.57 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr4_-_123118186 0.56 ENSRNOT00000038096
coiled-coil-helix-coiled-coil-helix domain containing 4
chr12_-_24365324 0.56 ENSRNOT00000032250
tripartite motif-containing 50
chr5_-_56576676 0.56 ENSRNOT00000029712
NADH:ubiquinone oxidoreductase subunit B6
chr8_-_130491998 0.55 ENSRNOT00000064114
HIG1 hypoxia inducible domain family, member 1A
chr9_+_80118029 0.55 ENSRNOT00000023068
insulin-like growth factor binding protein 2
chr7_+_11724962 0.54 ENSRNOT00000026551
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_-_60813869 0.54 ENSRNOT00000058234
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr14_+_43694183 0.53 ENSRNOT00000046342
similar to ribosomal protein S23
chr1_-_167347490 0.53 ENSRNOT00000076499
ras homolog family member G
chr2_-_119140110 0.52 ENSRNOT00000058810

chr7_+_35125424 0.52 ENSRNOT00000085978
ENSRNOT00000010117
NADH:ubiquinone oxidoreductase subunit A12
chr3_+_2480232 0.52 ENSRNOT00000014489
taperin
chr8_+_116094851 0.52 ENSRNOT00000084120
similar to RIKEN cDNA 6430571L13 gene; similar to g20 protein
chr5_-_157573183 0.51 ENSRNOT00000064418
mitochondrial inner membrane organizing system 1
chr8_+_48437918 0.51 ENSRNOT00000085578
membrane frizzled-related protein
chr19_+_10596960 0.50 ENSRNOT00000021769
cytokine induced apoptosis inhibitor 1
chr14_-_84937725 0.48 ENSRNOT00000083839
ubiquinol-cytochrome c reductase, complex III subunit X
chr12_-_30566032 0.48 ENSRNOT00000093378
glioblastoma amplified sequence
chr11_+_64472072 0.47 ENSRNOT00000042756
similar to ribosomal protein L27
chr17_+_15845931 0.47 ENSRNOT00000092083
caspase recruitment domain family, member 19
chr6_-_135939534 0.47 ENSRNOT00000052237
DIRAS family GTPase 3
chr20_-_3818045 0.47 ENSRNOT00000091622
hydroxysteroid (17-beta) dehydrogenase 8
chr12_-_44174583 0.46 ENSRNOT00000001490
tescalcin
chr6_-_135412312 0.46 ENSRNOT00000010610
ankyrin repeat domain 9
chr2_-_140464607 0.45 ENSRNOT00000058190
NADH:ubiquinone oxidoreductase subunit C1
chr19_+_26084903 0.45 ENSRNOT00000004799
peroxiredoxin 2
chr20_-_5618254 0.45 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr4_+_66405166 0.44 ENSRNOT00000077486
ENSRNOT00000067097
C-type lectin domain family 2, member L
chr15_+_41069507 0.43 ENSRNOT00000018533
C1q and tumor necrosis factor related protein 9
chr19_-_54245855 0.43 ENSRNOT00000023855
ER membrane protein complex subunit 8
chrX_+_33443186 0.43 ENSRNOT00000005622
S100 calcium binding protein G
chr6_-_136145837 0.43 ENSRNOT00000015122
creatine kinase B
chr10_-_38782419 0.42 ENSRNOT00000073964
ubiquinol-cytochrome c reductase, complex III subunit VII
chr7_+_2504695 0.42 ENSRNOT00000003965
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr11_-_32088002 0.42 ENSRNOT00000002732
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr4_+_67378188 0.42 ENSRNOT00000030892
NADH:ubiquinone oxidoreductase subunit B2
chr15_+_2631529 0.41 ENSRNOT00000018897
catechol-O-methyltransferase domain containing 1
chr9_+_61692154 0.41 ENSRNOT00000082300
heat shock protein family E member 1
chr10_-_5533695 0.41 ENSRNOT00000051564
ribosomal protein L39-like
chr4_-_130659697 0.41 ENSRNOT00000072374
rCG56280-like
chr10_-_40375605 0.41 ENSRNOT00000014464
annexin A6
chr3_+_113318563 0.39 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr11_-_72109964 0.39 ENSRNOT00000058917

chr8_-_23014499 0.38 ENSRNOT00000017820
coiled-coil domain containing 151
chr9_-_92291220 0.38 ENSRNOT00000093357
delta/notch-like EGF repeat containing
chr18_+_74156553 0.38 ENSRNOT00000022892
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr1_+_72882806 0.36 ENSRNOT00000024640
troponin I3, cardiac type
chr4_+_165732643 0.36 ENSRNOT00000034403
hypothetical protein LOC690326
chr1_+_31264755 0.36 ENSRNOT00000028988
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr2_+_119139717 0.36 ENSRNOT00000016051
NADH:ubiquinone oxidoreductase subunit B5
chr14_+_60764409 0.36 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr20_-_13657943 0.35 ENSRNOT00000032290
pre-B lymphocyte 3
chr14_-_93042182 0.35 ENSRNOT00000005432
protein arginine methyltransferase 1-like
chr10_-_102289837 0.35 ENSRNOT00000044922

chr13_-_36101411 0.35 ENSRNOT00000074471
transmembrane protein 37
chr16_-_81243757 0.34 ENSRNOT00000024677
growth arrest specific 6
chr11_+_70687500 0.34 ENSRNOT00000037432

chr14_+_86673775 0.34 ENSRNOT00000091873
ENSRNOT00000079015
peptidylprolyl isomerase A
chr18_+_70733872 0.34 ENSRNOT00000067018
acetyl-CoA acyltransferase 2
chr10_-_91448477 0.34 ENSRNOT00000038836
Rho GTPase activating protein 27
chr20_-_7208292 0.34 ENSRNOT00000083169
nudix hydrolase 3
chr11_+_37798370 0.34 ENSRNOT00000002679
beta-site APP-cleaving enzyme 2
chr7_+_117409576 0.33 ENSRNOT00000017067
cytochrome c-1
chr6_+_24163026 0.33 ENSRNOT00000061284
limb bud and heart development
chr19_+_54245950 0.32 ENSRNOT00000024033
cytochrome c oxidase subunit 4i1
chr8_+_55037750 0.32 ENSRNOT00000013188
translocase of inner mitochondrial membrane 8 homolog B
chr8_+_106317124 0.32 ENSRNOT00000018411
nicotinamide nucleotide adenylyltransferase 3
chr6_+_128750795 0.32 ENSRNOT00000005781
glutaredoxin 5
chr1_-_253186695 0.32 ENSRNOT00000080928

chr14_-_79464770 0.32 ENSRNOT00000008932
GrpE-like 1, mitochondrial
chr2_-_260115577 0.32 ENSRNOT00000065997
Rab geranylgeranyltransferase, beta subunit
chr1_+_261158261 0.31 ENSRNOT00000071965
phosphoglycerate mutase 1
chr1_+_221773254 0.31 ENSRNOT00000028646
RAS guanyl releasing protein 2
chr8_+_117679278 0.31 ENSRNOT00000042114
ubiquinol-cytochrome c reductase core protein I
chr2_-_88113029 0.31 ENSRNOT00000013354
carbonic anhydrase 2
chr12_+_25264192 0.30 ENSRNOT00000079392
GTF2I repeat domain containing 1
chr10_-_13107771 0.30 ENSRNOT00000005879
FLYWCH-type zinc finger 1
chr14_-_80680738 0.29 ENSRNOT00000077706
smoothelin-like
chr5_+_150032999 0.29 ENSRNOT00000013301
serine and arginine rich splicing factor 4
chr5_+_141560192 0.29 ENSRNOT00000023354
Myc binding protein
chr5_-_75319765 0.28 ENSRNOT00000085698
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr3_+_113319456 0.28 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chr11_-_81379640 0.28 ENSRNOT00000002484
eukaryotic translation initiation factor 4A2
chr7_-_11018160 0.28 ENSRNOT00000092061
amino-terminal enhancer of split
chr10_-_90356242 0.28 ENSRNOT00000028496
solute carrier family 25, member 39
chr4_+_115046693 0.28 ENSRNOT00000031583
bolA family member 3
chr7_-_74735650 0.28 ENSRNOT00000014407
cytochrome c oxidase subunit 6C
chrX_-_113584459 0.28 ENSRNOT00000025923
potassium voltage-gated channel subfamily E regulatory subunit 5
chr1_-_89488223 0.28 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr4_-_157331905 0.28 ENSRNOT00000020647
triosephosphate isomerase 1
chr2_+_202200797 0.27 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr6_+_8669722 0.27 ENSRNOT00000048550
calmodulin-lysine N-methyltransferase
chr1_+_226252226 0.27 ENSRNOT00000039369

chr15_+_33606124 0.27 ENSRNOT00000065210

chr9_-_43127887 0.26 ENSRNOT00000021685
ankyrin repeat domain 39
chr14_+_89314176 0.26 ENSRNOT00000006765
uridine phosphorylase 1
chr8_-_68312909 0.26 ENSRNOT00000066106
similar to ENSANGP00000021391
chr9_+_90880614 0.26 ENSRNOT00000077859
ENSRNOT00000020705
ENSRNOT00000089142
mitochondrial fission factor
chr12_-_40227297 0.26 ENSRNOT00000030600
family with sequence similarity 109, member A
chr9_+_20213776 0.26 ENSRNOT00000071439
triosephosphate isomerase-like
chr7_+_129860327 0.26 ENSRNOT00000043461
Pim-3 proto-oncogene, serine/threonine kinase
chr6_+_55085313 0.25 ENSRNOT00000005458

chr6_+_126434226 0.25 ENSRNOT00000090857
chromogranin A
chr3_-_123702732 0.25 ENSRNOT00000028859
similar to RIKEN cDNA 1700037H04
chr9_+_81566074 0.24 ENSRNOT00000074131
ENSRNOT00000046229
ENSRNOT00000090383
paroxysmal nonkinesigenic dyskinesia
chr4_+_122781095 0.24 ENSRNOT00000008962
histone deacetylase 11
chr8_+_118378059 0.24 ENSRNOT00000043247

chr4_-_157679962 0.24 ENSRNOT00000050443
glyceraldehyde-3-phosphate dehydrogenase
chr3_-_122813583 0.24 ENSRNOT00000009681
isocitrate dehydrogenase 3 (NAD+) beta
chr9_-_16647458 0.24 ENSRNOT00000024380
mitochondrial ribosomal protein L2
chr20_+_18493538 0.24 ENSRNOT00000000749
CDGSH iron sulfur domain 1
chr4_-_28953067 0.24 ENSRNOT00000013989
tissue factor pathway inhibitor 2
chr16_+_19874034 0.23 ENSRNOT00000023579
mitochondrial ribosomal protein L34
chr17_-_2705123 0.23 ENSRNOT00000024940
olfactory receptor 1652
chr20_+_21316826 0.23 ENSRNOT00000000785
similar to RIKEN cDNA 1700040L02
chr8_-_130429132 0.23 ENSRNOT00000026261
hedgehog acyltransferase-like
chr20_-_6961162 0.23 ENSRNOT00000000635
mitochondrial carrier 1
chr3_+_72226613 0.23 ENSRNOT00000010619
translocase of inner mitochondrial membrane 10
chr14_-_44375804 0.23 ENSRNOT00000042825
ribosomal protein P2-like
chr5_+_173640780 0.23 ENSRNOT00000027476
PPARGC1 and ESRR induced regulator, muscle 1
chr8_-_128711221 0.22 ENSRNOT00000055888
xin actin-binding repeat containing 1
chr8_-_128266639 0.22 ENSRNOT00000064555
ENSRNOT00000066932
sodium voltage-gated channel alpha subunit 5
chr3_+_4083864 0.22 ENSRNOT00000006186
family with sequence similarity 69, member B
chr1_+_100593680 0.22 ENSRNOT00000078153
ENSRNOT00000027063
potassium voltage-gated channel subfamily C member 3
chr8_+_116857684 0.22 ENSRNOT00000026711
macrophage stimulating 1
chr5_+_159484370 0.22 ENSRNOT00000010593
succinate dehydrogenase complex iron sulfur subunit B
chr5_+_147185474 0.22 ENSRNOT00000000134
adenylate kinase 2
chr4_+_155313671 0.21 ENSRNOT00000020812
microfibrillar associated protein 5
chr13_-_93677377 0.21 ENSRNOT00000004917
fumarate hydratase
chr9_-_71830730 0.21 ENSRNOT00000019963
crystallin, gamma A
chr1_+_89162639 0.21 ENSRNOT00000028508
ATPase H+/K+ transporting alpha subunit
chr15_+_4351292 0.20 ENSRNOT00000009207
mitochondrial ribosomal protein S16
chr10_+_64556064 0.20 ENSRNOT00000010778
translocase of inner mitochondrial membrane 22
chr3_-_1584946 0.20 ENSRNOT00000031058
paired box 8
chr5_+_151741817 0.20 ENSRNOT00000081318
keratinocyte differentiation factor 1
chr13_-_95943761 0.20 ENSRNOT00000005961
adenylosuccinate synthase
chr3_-_47025128 0.20 ENSRNOT00000011682
RNA binding motif, single stranded interacting protein 1
chr10_+_64930023 0.20 ENSRNOT00000071102

chr17_+_85356042 0.19 ENSRNOT00000022201
COMM domain containing 3
chr7_-_127058056 0.19 ENSRNOT00000022882
ceramide kinase
chr12_-_30180115 0.19 ENSRNOT00000001202
CGRP receptor component
chr8_-_13513337 0.19 ENSRNOT00000071532
lysine-specific demethylase 4D
chr2_+_212257225 0.19 ENSRNOT00000077883
vav guanine nucleotide exchange factor 3
chr5_-_59149625 0.19 ENSRNOT00000040641
ENSRNOT00000084216
sperm associated antigen 8
chr7_-_12519154 0.19 ENSRNOT00000093376
ENSRNOT00000077681
glutathione peroxidase 4
chr2_+_150211898 0.19 ENSRNOT00000018767
succinate receptor 1
chr3_+_61756148 0.19 ENSRNOT00000002134
metaxin 2
chr10_-_56429748 0.19 ENSRNOT00000020675
ENSRNOT00000092704
spermatid maturation 1
chr1_-_263269762 0.19 ENSRNOT00000022309
glutamic-oxaloacetic transaminase 1
chr13_-_51183269 0.19 ENSRNOT00000039540
PTPRF interacting protein alpha 4
chr14_+_17615968 0.18 ENSRNOT00000003470
ring finger and CHY zinc finger domain containing 1
chr10_-_97582188 0.18 ENSRNOT00000005076
regulator of G-protein signaling 9
chr6_-_93562314 0.18 ENSRNOT00000010871
ENSRNOT00000088790
translocase of inner mitochondrial membrane 9
chr7_+_12229379 0.18 ENSRNOT00000060811
ADAMTS-like 5
chr10_+_10967658 0.18 ENSRNOT00000004999
cell death-inducing p53 target 1
chr5_+_157423213 0.18 ENSRNOT00000023431
transmembrane and coiled-coil domains 4
chr5_-_128333805 0.18 ENSRNOT00000037523
zinc finger FYVE-type containing 9
chr10_-_88677055 0.18 ENSRNOT00000025590
GH3 domain containing
chr5_-_2803855 0.18 ENSRNOT00000009490
ribosomal protein S8-like
chr15_+_7871497 0.18 ENSRNOT00000046879
ubiquitin-conjugating enzyme E2E 2
chr7_-_12432130 0.18 ENSRNOT00000077301
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr3_-_103857158 0.17 ENSRNOT00000007612
ER membrane protein complex subunit 4
chrX_+_63542191 0.17 ENSRNOT00000073955
apolipoprotein O
chr9_+_116652530 0.17 ENSRNOT00000029210
l(3)mbt-like 4 (Drosophila)
chr8_-_87213627 0.17 ENSRNOT00000066084
cytochrome c oxidase subunit 7A2
chr10_-_84915471 0.17 ENSRNOT00000087322
Sp2 transcription factor
chr1_+_85460888 0.17 ENSRNOT00000093384
SPT5 homolog, DSIF elongation factor subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrb_Esrra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.5 1.6 GO:0060066 oviduct development(GO:0060066)
0.4 1.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.4 1.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic hindgut morphogenesis(GO:0048619)
0.3 1.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 0.9 GO:0003331 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of renal output by angiotensin(GO:0002019) angiotensin-mediated drinking behavior(GO:0003051) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) positive regulation of gap junction assembly(GO:1903598)
0.3 0.8 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.5 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.4 GO:0021539 subthalamus development(GO:0021539)
0.1 1.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.2 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.5 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 1.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.5 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.1 0.4 GO:0002339 B cell selection(GO:0002339) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.3 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.1 GO:0097214 regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) negative regulation of long term synaptic depression(GO:1900453)
0.1 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.1 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.3 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.2 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 1.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.2 GO:1903059 regulation of protein lipidation(GO:1903059)
0.0 0.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:1901367 response to L-cysteine(GO:1901367)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.3 GO:0046133 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:1905242 slow-twitch skeletal muscle fiber contraction(GO:0031444) response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243)
0.0 0.1 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0009188 ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0072138 cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.6 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.8 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.1 GO:0009751 response to salicylic acid(GO:0009751)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.1 GO:0098705 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0032912 endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta1 production(GO:0032911) negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.2 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.0 GO:1903165 response to polycyclic arene(GO:1903165)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0043179 rhythmic excitation(GO:0043179)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0000105 histidine biosynthetic process(GO:0000105)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0061198 fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.1 GO:2001271 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.0 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 3.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.0 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.5 GO:0045273 respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.3 GO:0045242 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 3.8 GO:0070469 respiratory chain(GO:0070469)
0.1 0.3 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 5.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 2.5 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.2 5.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.2 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.5 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.2 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.4 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.9 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 1.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 7.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 5.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)